IMP

Process View

Homo sapiens

12 genes annotated in human

Multi-species View

positive regulation of b cell proliferation

GO:0030890

Any process that activates or increases the rate or extent of B cell proliferation.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of b cell proliferation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of b cell proliferation" (in gray)

Name	Description	Probability	Func Analog Organism
BCL2L1	BCL2-like 1	0.989	Human
BCL2	B-cell CLL/lymphoma 2	0.788
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.510
LAT	linker for activation of T cells	0.320
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.276	Human
GRB2	growth factor receptor-bound protein 2	0.238
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.211
IL4R	interleukin 4 receptor	0.195
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.164
SMN1	survival of motor neuron 1, telomeric	0.161
TICAM2	toll-like receptor adaptor molecule 2	0.138
MYD88	myeloid differentiation primary response gene (88)	0.133
BAX	BCL2-associated X protein	0.113	Human
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.098
TAL1	T-cell acute lymphocytic leukemia 1	0.082
EP300	E1A binding protein p300	0.071
IRAK1	interleukin-1 receptor-associated kinase 1	0.069
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.064
BAD	BCL2-associated agonist of cell death	0.060
BAK1	BCL2-antagonist/killer 1	0.055
SH3BP2	SH3-domain binding protein 2	0.055
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.054
IRAK2	interleukin-1 receptor-associated kinase 2	0.053
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.047
SYK	spleen tyrosine kinase	0.047
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.045
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.042
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.042
GAS7	growth arrest-specific 7	0.039
TRAF6	TNF receptor-associated factor 6	0.038
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.037
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.037
TRAF1	TNF receptor-associated factor 1	0.035
CD247	CD247 molecule	0.034
ADAM15	ADAM metallopeptidase domain 15	0.030
TLR4	toll-like receptor 4	0.028	Mouse
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.028
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.027
NCOR2	nuclear receptor corepressor 2	0.027
LY96	lymphocyte antigen 96	0.027
PCDH9	protocadherin 9	0.026
RNF2	ring finger protein 2	0.026
IRS1	insulin receptor substrate 1	0.026
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.025
IL2RG	interleukin 2 receptor, gamma	0.024
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.023
BID	BH3 interacting domain death agonist	0.023
HDAC9	histone deacetylase 9	0.023
CXCR4	chemokine (C-X-C motif) receptor 4	0.022
GRB10	growth factor receptor-bound protein 10	0.022
TRAF3	TNF receptor-associated factor 3	0.021
LCK	lymphocyte-specific protein tyrosine kinase	0.021
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.020	Mouse
RUNX1	runt-related transcription factor 1	0.019
BCL10	B-cell CLL/lymphoma 10	0.019
TCF4	transcription factor 4	0.019	Human
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.018
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.018
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.017
RNF144B	ring finger protein 144B	0.017
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.017
HDAC4	histone deacetylase 4	0.017
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.017
BIRC3	baculoviral IAP repeat containing 3	0.016
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.016
TRAF2	TNF receptor-associated factor 2	0.016
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.016
CYSLTR1	cysteinyl leukotriene receptor 1	0.015	Human
BLNK	B-cell linker	0.015
SOS1	son of sevenless homolog 1 (Drosophila)	0.015
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.014
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.014
SLA	Src-like-adaptor	0.013
PRKCQ	protein kinase C, theta	0.013
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.013
SIRT1	sirtuin 1	0.013
FERMT2	fermitin family member 2	0.012
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.012
INSR	insulin receptor	0.012
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.012
PTEN	phosphatase and tensin homolog	0.012
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.011
CD22	CD22 molecule	0.011
NCOA3	nuclear receptor coactivator 3	0.011
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.011
TCF12	transcription factor 12	0.011	Human
GPI	glucose-6-phosphate isomerase	0.011
ADRB2	adrenergic, beta-2-, receptor, surface	0.010
CHN2	chimerin (chimaerin) 2	0.010
SH2D2A	SH2 domain containing 2A	0.010