IMP

Process View

Homo sapiens

13 genes annotated in human

Multi-species View

tyrosine phosphorylation of stat5 protein

GO:0042506

The process of introducing a phosphate group to a tyrosine residue of a Stat5 protein.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "tyrosine phosphorylation of stat5 protein"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "tyrosine phosphorylation of stat5 protein" (in gray)

Name	Description	Probability	Func Analog Organism
EGFR	epidermal growth factor receptor	1.000	Human
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	1.000	Human
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	1.000	Human
FYN	FYN oncogene related to SRC, FGR, YES	1.000	Human
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.998	Human
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.997
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.995
GRB2	growth factor receptor-bound protein 2	0.987
SYK	spleen tyrosine kinase	0.950
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.927
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.917
GH1	growth hormone 1	0.857
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.830
PTPRB	protein tyrosine phosphatase, receptor type, B	0.692
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.664	Human
IL4R	interleukin 4 receptor	0.645
VEGFA	vascular endothelial growth factor A	0.619
PLCG1	phospholipase C, gamma 1	0.600
CSH1	chorionic somatomammotropin hormone 1 (placental lactogen)	0.592	Human
IL23A	interleukin 23, alpha subunit p19	0.561
JAK2	Janus kinase 2	0.534	Mouse Rat
SOCS3	suppressor of cytokine signaling 3	0.461
GHR	growth hormone receptor	0.458
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.413
NRP1	neuropilin 1	0.413
HCK	hemopoietic cell kinase	0.407	Human
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.384
CSH2	chorionic somatomammotropin hormone 2	0.360	Human
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.266
GAB1	GRB2-associated binding protein 1	0.259
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.258
MED28	mediator complex subunit 28	0.237
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.232
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.231
EPOR	erythropoietin receptor	0.225
IRS1	insulin receptor substrate 1	0.221
CD44	CD44 molecule (Indian blood group)	0.219
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.206	Human
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.198
SPRR2A	small proline-rich protein 2A	0.185
SLA	Src-like-adaptor	0.177
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.175	Human
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.173
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.172
SH3KBP1	SH3-domain kinase binding protein 1	0.169
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.164	Human
GRB7	growth factor receptor-bound protein 7	0.150
CSHL1	chorionic somatomammotropin hormone-like 1	0.146	Human
INSR	insulin receptor	0.139
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.130
GH2	growth hormone 2	0.127	Human
BLNK	B-cell linker	0.125
LAT	linker for activation of T cells	0.115
SOS1	son of sevenless homolog 1 (Drosophila)	0.113
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.108
IGF1R	insulin-like growth factor 1 receptor	0.104
STAT5A	signal transducer and activator of transcription 5A	0.104
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.099
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.098
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.097
ITGB1BP3	integrin beta 1 binding protein 3	0.088
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.084
SCHIP1	schwannomin interacting protein 1	0.078
FGFR1	fibroblast growth factor receptor 1	0.078
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.069
IGF2R	insulin-like growth factor 2 receptor	0.064
PTEN	phosphatase and tensin homolog	0.063
CDH5	cadherin 5, type 2 (vascular endothelium)	0.059
PGF	placental growth factor	0.055
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.054
CD2AP	CD2-associated protein	0.050
GAB2	GRB2-associated binding protein 2	0.049
PDCD6IP	programmed cell death 6 interacting protein	0.048
CAV2	caveolin 2	0.042
PDGFA	platelet-derived growth factor alpha polypeptide	0.041
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.041
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.039
IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	0.037
JAK1	Janus kinase 1	0.037
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.037
DLG4	discs, large homolog 4 (Drosophila)	0.035
KITLG	KIT ligand	0.035
LCK	lymphocyte-specific protein tyrosine kinase	0.034	Human Mouse
PROX1	prospero homeobox 1	0.031
ITK	IL2-inducible T-cell kinase	0.029
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.028
SREBF2	sterol regulatory element binding transcription factor 2	0.026
PDGFC	platelet derived growth factor C	0.026
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.024
UBASH3B	ubiquitin associated and SH3 domain containing B	0.023
CD33	CD33 molecule	0.023
IFNGR1	interferon gamma receptor 1	0.022
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.022	Human
NCK1	NCK adaptor protein 1	0.020
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.020
SOCS1	suppressor of cytokine signaling 1	0.020
VAV1	vav 1 guanine nucleotide exchange factor	0.020
VAV3	vav 3 guanine nucleotide exchange factor	0.020
PRKCQ	protein kinase C, theta	0.019
PECAM1	platelet/endothelial cell adhesion molecule	0.019
RET	ret proto-oncogene	0.019
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.018
EZR	ezrin	0.017	Human
STAT1	signal transducer and activator of transcription 1, 91kDa	0.017
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.016
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.016
BCAR1	breast cancer anti-estrogen resistance 1	0.016
FAF1	Fas (TNFRSF6) associated factor 1	0.016
ESRRG	estrogen-related receptor gamma	0.016
SH3BP2	SH3-domain binding protein 2	0.015
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.014
DCN	decorin	0.014
ITGA1	integrin, alpha 1	0.014
BTK	Bruton agammaglobulinemia tyrosine kinase	0.014	Human
IGFBP3	insulin-like growth factor binding protein 3	0.013
SPRY4	sprouty homolog 4 (Drosophila)	0.013
NRG1	neuregulin 1	0.013
TNS4	tensin 4	0.012
JAK3	Janus kinase 3	0.012	Rat
HCLS1	hematopoietic cell-specific Lyn substrate 1	0.012
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.011
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.011
FRS2	fibroblast growth factor receptor substrate 2	0.011
CNTF	ciliary neurotrophic factor	0.011
FYB	FYN binding protein	0.011
CD22	CD22 molecule	0.011
TAGLN2	transgelin 2	0.011
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.011
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.010
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.010
VAV2	vav 2 guanine nucleotide exchange factor	0.010
SH2B2	SH2B adaptor protein 2	0.010
YAP1	Yes-associated protein 1	0.010