IMP

Process View

Homo sapiens

3 genes annotated in human

proteasomal ubiquitin independent protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "proteasomal ubiquitin independent protein catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "proteasomal ubiquitin independent protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	0.999	Yeast
PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6	0.998	Yeast
PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	0.998	Yeast
POMP	proteasome maturation protein	0.997
PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7	0.997	Yeast
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.996
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	0.994	Yeast
PSMB4	proteasome (prosome, macropain) subunit, beta type, 4	0.994	Yeast
PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	0.994
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.992
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	0.992	Yeast
PSMB1	proteasome (prosome, macropain) subunit, beta type, 1	0.991	Yeast
CUL3	cullin 3	0.988
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.985
PSMB3	proteasome (prosome, macropain) subunit, beta type, 3	0.984	Yeast
PSMB6	proteasome (prosome, macropain) subunit, beta type, 6	0.984	Yeast
PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	0.982	Yeast
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.980
PSMB5	proteasome (prosome, macropain) subunit, beta type, 5	0.949	Yeast
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	0.938
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.934
PSMB2	proteasome (prosome, macropain) subunit, beta type, 2	0.925	Yeast
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.890
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.880
PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.875
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.873
PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	0.837	Yeast
PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.802
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.714
PSMB10	proteasome (prosome, macropain) subunit, beta type, 10	0.668	Yeast
KEAP1	kelch-like ECH-associated protein 1	0.649
PSMD8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	0.598
WNK4	WNK lysine deficient protein kinase 4	0.588
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.534
DAPK1	death-associated protein kinase 1	0.513
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	0.443
PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	0.395	Yeast
PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.341
PSMD14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	0.279
PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.257
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.126
NFE2L1	nuclear factor (erythroid-derived 2)-like 1	0.126	Human
BTBD10	BTB (POZ) domain containing 10	0.084
PRDX1	peroxiredoxin 1	0.082
KBTBD7	kelch repeat and BTB (POZ) domain containing 7	0.082
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.077
SPOP	speckle-type POZ protein	0.073
CSNK1A1	casein kinase 1, alpha 1	0.069
COIL	coilin	0.059
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.059
RAD23A	RAD23 homolog A (S. cerevisiae)	0.058
SLX1B	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)	0.054
MED28	mediator complex subunit 28	0.046
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.043
LNX1	ligand of numb-protein X 1	0.041
TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.038
TBCB	tubulin folding cofactor B	0.037
SHFM1	split hand/foot malformation (ectrodactyly) type 1	0.032
TRIP12	thyroid hormone receptor interactor 12	0.028
MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)	0.027
TAPBPL	TAP binding protein-like	0.026
NMI	N-myc (and STAT) interactor	0.026
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.026
PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.025
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.025	Human
PRR13	proline rich 13	0.024
DPP3	dipeptidyl-peptidase 3	0.022
ZFAND5	zinc finger, AN1-type domain 5	0.021
TSC22D4	TSC22 domain family, member 4	0.021
PRMT6	protein arginine methyltransferase 6	0.021
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.020
PFN2	profilin 2	0.018
UCHL5	ubiquitin carboxyl-terminal hydrolase L5	0.018
KLHDC5	kelch domain containing 5	0.018
BAG3	BCL2-associated athanogene 3	0.018
KLHL20	kelch-like 20 (Drosophila)	0.018	Human
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.016
EIF2AK3	eukaryotic translation initiation factor 2-alpha kinase 3	0.016
SNX20	sorting nexin 20	0.016
DCUN1D5	DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)	0.015
TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	0.015
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.015
FOXP1	forkhead box P1	0.014
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.014
AHR	aryl hydrocarbon receptor	0.013
CUL1	cullin 1	0.013
GSTO1	glutathione S-transferase omega 1	0.013
SGMS1	sphingomyelin synthase 1	0.012
BANP	BTG3 associated nuclear protein	0.012
DDIT3	DNA-damage-inducible transcript 3	0.012
KLHL2	kelch-like 2, Mayven (Drosophila)	0.012	Human
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.012
CPSF6	cleavage and polyadenylation specific factor 6, 68kDa	0.012
HOOK3	hook homolog 3 (Drosophila)	0.012
TXNL1	thioredoxin-like 1	0.012
ARMC8	armadillo repeat containing 8	0.012
OSTF1	osteoclast stimulating factor 1	0.012
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.011
TMSB10	thymosin beta 10	0.011
FAM98A	family with sequence similarity 98, member A	0.011
LARP4B	La ribonucleoprotein domain family, member 4B	0.011
CSDE1	cold shock domain containing E1, RNA-binding	0.011
C20orf24	chromosome 20 open reading frame 24	0.011
KIAA0232	KIAA0232	0.011
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.011
SERGEF	secretion regulating guanine nucleotide exchange factor	0.010
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.010
PDCD6	programmed cell death 6	0.010
KBTBD2	kelch repeat and BTB (POZ) domain containing 2	0.010
ZBTB43	zinc finger and BTB domain containing 43	0.010