IMP

Process View

Homo sapiens

13 genes annotated in human

negative regulation of cytokine production involved in immune response

Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cytokine production involved in immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of cytokine production involved in immune response" (in gray)

Name	Description	Probability	Func Analog Organism
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.983
ALB	albumin	0.975
CCR5	chemokine (C-C motif) receptor 5	0.970
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.956
CCL4	chemokine (C-C motif) ligand 4	0.909	Human
PILRA	paired immunoglobin-like type 2 receptor alpha	0.828
CXCL9	chemokine (C-X-C motif) ligand 9	0.726
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.699	Human
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.657	Human
CCL5	chemokine (C-C motif) ligand 5	0.623	Human
CCR1	chemokine (C-C motif) receptor 1	0.591
HK3	hexokinase 3 (white cell)	0.532
HP	haptoglobin	0.492
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.448
IL10RA	interleukin 10 receptor, alpha	0.432
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.431
SIGLEC7	sialic acid binding Ig-like lectin 7	0.426
CCL8	chemokine (C-C motif) ligand 8	0.414	Human
IL1B	interleukin 1, beta	0.390
APOC1	apolipoprotein C-I	0.375
IFNG	interferon, gamma	0.345
IRAK2	interleukin-1 receptor-associated kinase 2	0.305
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.277	Human
IL22RA1	interleukin 22 receptor, alpha 1	0.258
A2M	alpha-2-macroglobulin	0.253
IDE	insulin-degrading enzyme	0.237
CCL22	chemokine (C-C motif) ligand 22	0.210	Human
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.206	Human
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.200
CCR7	chemokine (C-C motif) receptor 7	0.197
IL22RA2	interleukin 22 receptor, alpha 2	0.193
DPP4	dipeptidyl-peptidase 4	0.183
CCL7	chemokine (C-C motif) ligand 7	0.147	Human
CCL13	chemokine (C-C motif) ligand 13	0.132	Human
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.130
APOA1	apolipoprotein A-I	0.120
CCR4	chemokine (C-C motif) receptor 4	0.116
CCL3	chemokine (C-C motif) ligand 3	0.104	Human
CCL2	chemokine (C-C motif) ligand 2	0.104	Human
CXCL10	chemokine (C-X-C motif) ligand 10	0.103
PTAFR	platelet-activating factor receptor	0.102
SOCS3	suppressor of cytokine signaling 3	0.099
NLRP3	NLR family, pyrin domain containing 3	0.091
CXCL13	chemokine (C-X-C motif) ligand 13	0.090
TREM1	triggering receptor expressed on myeloid cells 1	0.088
FPR3	formyl peptide receptor 3	0.086
EBI3	Epstein-Barr virus induced 3	0.084
HDAC9	histone deacetylase 9	0.080
TGFB1	transforming growth factor, beta 1	0.076
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.075
IL8	interleukin 8	0.074
ENG	endoglin	0.070
CXCL11	chemokine (C-X-C motif) ligand 11	0.069
CD14	CD14 molecule	0.068
CCL19	chemokine (C-C motif) ligand 19	0.066	Human
CD80	CD80 molecule	0.066
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.064
IL6	interleukin 6 (interferon, beta 2)	0.061
IL10	interleukin 10	0.061
IL2RB	interleukin 2 receptor, beta	0.061
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.060
IL1RN	interleukin 1 receptor antagonist	0.060
FSTL1	follistatin-like 1	0.059
CD86	CD86 molecule	0.058
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.057
IL18RAP	interleukin 18 receptor accessory protein	0.056
CXCL2	chemokine (C-X-C motif) ligand 2	0.054
TYMP	thymidine phosphorylase	0.053
AQP9	aquaporin 9	0.051
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.046
PRF1	perforin 1 (pore forming protein)	0.043
CCL11	chemokine (C-C motif) ligand 11	0.041	Human
SLAMF7	SLAM family member 7	0.040
PCDH9	protocadherin 9	0.039
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.039
APOC2	apolipoprotein C-II	0.039
IRF4	interferon regulatory factor 4	0.038
ANGPT2	angiopoietin 2	0.033
CXCL3	chemokine (C-X-C motif) ligand 3	0.030
C2	complement component 2	0.030
LCAT	lecithin-cholesterol acyltransferase	0.030
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.030
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.029	Human
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.029
IL2RG	interleukin 2 receptor, gamma	0.028
CXCL5	chemokine (C-X-C motif) ligand 5	0.027
FPR2	formyl peptide receptor 2	0.027
ICAM1	intercellular adhesion molecule 1	0.027
NRP1	neuropilin 1	0.026
TNF	tumor necrosis factor	0.026
EPOR	erythropoietin receptor	0.026
TEK	TEK tyrosine kinase, endothelial	0.026
CCR3	chemokine (C-C motif) receptor 3	0.026
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.025
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.025
CCL1	chemokine (C-C motif) ligand 1	0.025	Human
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.024
BATF	basic leucine zipper transcription factor, ATF-like	0.023
CMKLR1	chemokine-like receptor 1	0.023
FCAR	Fc fragment of IgA, receptor for	0.023	Human
NCOR2	nuclear receptor corepressor 2	0.023
ADAMDEC1	ADAM-like, decysin 1	0.022
AOAH	acyloxyacyl hydrolase (neutrophil)	0.022
CD83	CD83 molecule	0.022
IL21R	interleukin 21 receptor	0.021
S100A12	S100 calcium binding protein A12	0.021
XCL1	chemokine (C motif) ligand 1	0.021
CSF3	colony stimulating factor 3 (granulocyte)	0.021
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.020
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.020
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.020
HAMP	hepcidin antimicrobial peptide	0.020
IL2RA	interleukin 2 receptor, alpha	0.019
KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	0.018
IL1A	interleukin 1, alpha	0.018
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.018
MARCO	macrophage receptor with collagenous structure	0.018
TGFB3	transforming growth factor, beta 3	0.018
CD33	CD33 molecule	0.017
CD40LG	CD40 ligand	0.017
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.017
IL13	interleukin 13	0.017
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.017
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.017
SIGLEC9	sialic acid binding Ig-like lectin 9	0.017
PPAP2B	phosphatidic acid phosphatase type 2B	0.016
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.016
IL4	interleukin 4	0.016
MSC	musculin	0.016
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.016
TGFBR1	transforming growth factor, beta receptor 1	0.015
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.015
CLEC5A	C-type lectin domain family 5, member A	0.015
CCL20	chemokine (C-C motif) ligand 20	0.015	Human
SIRPB1	signal-regulatory protein beta 1	0.015
CCL23	chemokine (C-C motif) ligand 23	0.015	Human
ZC3H12A	zinc finger CCCH-type containing 12A	0.015
ICOS	inducible T-cell co-stimulator	0.015
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.015
PLEK	pleckstrin	0.015
IL1R2	interleukin 1 receptor, type II	0.015
IL7R	interleukin 7 receptor	0.014
IFNB1	interferon, beta 1, fibroblast	0.014
IRAK1	interleukin-1 receptor-associated kinase 1	0.013
CH25H	cholesterol 25-hydroxylase	0.013
APOC3	apolipoprotein C-III	0.013
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.013
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.013
LGALS2	lectin, galactoside-binding, soluble, 2	0.013
LILRA5	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5	0.013	Human
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.013
TRAF1	TNF receptor-associated factor 1	0.012
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.012
SLAMF8	SLAM family member 8	0.012
CXCR3	chemokine (C-X-C motif) receptor 3	0.012
ROS1	c-ros oncogene 1 , receptor tyrosine kinase	0.012
INHBA	inhibin, beta A	0.012
HDAC5	histone deacetylase 5	0.012
GNLY	granulysin	0.012
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.012
TGFBR3	transforming growth factor, beta receptor III	0.012
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.011
STAT4	signal transducer and activator of transcription 4	0.011
OSM	oncostatin M	0.011
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.011
ARRB1	arrestin, beta 1	0.011
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.011
CSF1	colony stimulating factor 1 (macrophage)	0.011
CCL17	chemokine (C-C motif) ligand 17	0.011	Human
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.011
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.011	Human
NKG7	natural killer cell group 7 sequence	0.011
SLAMF1	signaling lymphocytic activation molecule family member 1	0.011
XCL2	chemokine (C motif) ligand 2	0.011	Human
EMR3	egf-like module containing, mucin-like, hormone receptor-like 3	0.010
SELE	selectin E	0.010
IL24	interleukin 24	0.010	Human
CXCR6	chemokine (C-X-C motif) receptor 6	0.010