Process View
51 genes annotated in human
DOID:10584
A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "retinitis pigmentosa"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
PRPF8 | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 0.959 | ||
DHX30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.956 | ||
CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 | 0.789 | ||
PRPF6 | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 0.784 | ||
SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.739 | ||
PRPF31 | PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) | 0.679 | ||
C2orf65 | chromosome 2 open reading frame 65 | 0.467 | ||
SART3 | squamous cell carcinoma antigen recognized by T cells 3 | 0.435 | ||
SLU7 | SLU7 splicing factor homolog (S. cerevisiae) | 0.403 | ||
IK | IK cytokine, down-regulator of HLA II | 0.329 | ||
SART1 | squamous cell carcinoma antigen recognized by T cells | 0.280 | ||
USP39 | ubiquitin specific peptidase 39 | 0.232 | ||
SF3A2 | splicing factor 3a, subunit 2, 66kDa | 0.227 | ||
EFTUD2 | elongation factor Tu GTP binding domain containing 2 | 0.165 | ||
RNF113A | ring finger protein 113A | 0.086 | ||
PHF5A | PHD finger protein 5A | 0.082 | ||
CDK9 | cyclin-dependent kinase 9 | 0.066 | ||
PLXND1 | plexin D1 | 0.066 | ||
SRRM2 | serine/arginine repetitive matrix 2 | 0.064 | ||
UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.052 | ||
PPIH | peptidylprolyl isomerase H (cyclophilin H) | 0.049 | ||
SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.048 | ||
INADL | InaD-like (Drosophila) | 0.045 | ||
CEP72 | centrosomal protein 72kDa | 0.042 | ||
SNRNP40 | small nuclear ribonucleoprotein 40kDa (U5) | 0.038 | ||
HNRNPH2 | heterogeneous nuclear ribonucleoprotein H2 (H') | 0.033 | ||
SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.031 | ||
PLXNB2 | plexin B2 | 0.031 | ||
ARL3 | ADP-ribosylation factor-like 3 | 0.029 | ||
MEPCE | methylphosphate capping enzyme | 0.028 | ||
HUWE1 | HECT, UBA and WWE domain containing 1 | 0.027 | ||
PFDN4 | prefoldin subunit 4 | 0.026 | ||
BUD13 | BUD13 homolog (S. cerevisiae) | 0.026 | ||
SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.026 | ||
PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta | 0.026 | ||
TXNL4A | thioredoxin-like 4A | 0.025 | ||
RBM4 | RNA binding motif protein 4 | 0.025 | ||
MYBBP1A | MYB binding protein (P160) 1a | 0.024 | ||
CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.024 | ||
NSFL1C | NSFL1 (p97) cofactor (p47) | 0.023 | ||
WBP11 | WW domain binding protein 11 | 0.023 | ||
SLC4A1 | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) | 0.023 | ||
SMNDC1 | survival motor neuron domain containing 1 | 0.023 | ||
GPKOW | G patch domain and KOW motifs | 0.023 | ||
IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha | 0.023 | ||
FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.022 | ||
PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.021 | ||
HDAC3 | histone deacetylase 3 | 0.021 | ||
PQBP1 | polyglutamine binding protein 1 | 0.020 | ||
AKNA | AT-hook transcription factor | 0.020 | ||
DHX16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 0.020 | ||
PRPF3 | PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae) | 0.019 | ||
WDR83 | WD repeat domain 83 | 0.019 | ||
SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.019 | ||
NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit | 0.018 | ||
OXA1L | oxidase (cytochrome c) assembly 1-like | 0.018 | ||
MMS19 | MMS19 nucleotide excision repair homolog (S. cerevisiae) | 0.018 | ||
MAX | MYC associated factor X | 0.017 | ||
ARL2 | ADP-ribosylation factor-like 2 | 0.017 | ||
TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.016 | ||
ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.016 | ||
FBXW8 | F-box and WD repeat domain containing 8 | 0.016 | ||
ARR3 | arrestin 3, retinal (X-arrestin) | 0.016 | Human | |
RBM25 | RNA binding motif protein 25 | 0.016 | ||
PCBP2 | poly(rC) binding protein 2 | 0.016 | ||
C20orf43 | chromosome 20 open reading frame 43 | 0.016 | ||
GFAP | glial fibrillary acidic protein | 0.016 | ||
POLR3F | polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa | 0.015 | ||
DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.015 | ||
GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 0.015 | ||
CRY1 | cryptochrome 1 (photolyase-like) | 0.015 | ||
SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 | 0.015 | ||
C20orf4 | chromosome 20 open reading frame 4 | 0.015 | ||
BFAR | bifunctional apoptosis regulator | 0.015 | ||
GMEB1 | glucocorticoid modulatory element binding protein 1 | 0.015 | ||
MDFI | MyoD family inhibitor | 0.015 | ||
GNAT1 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 | 0.014 | ||
PDE6G | phosphodiesterase 6G, cGMP-specific, rod, gamma | 0.014 | ||
PIGA | phosphatidylinositol glycan anchor biosynthesis, class A | 0.014 | ||
ZNRF1 | zinc and ring finger 1 | 0.014 | ||
NDUFV1 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | 0.014 | ||
FIZ1 | FLT3-interacting zinc finger 1 | 0.014 | ||
ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.014 | ||
BCL10 | B-cell CLL/lymphoma 10 | 0.013 | ||
HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.013 | ||
ARFGAP2 | ADP-ribosylation factor GTPase activating protein 2 | 0.013 | ||
HNF1A | HNF1 homeobox A | 0.013 | ||
HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.013 | ||
CDK5RAP1 | CDK5 regulatory subunit associated protein 1 | 0.013 | ||
CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.013 | ||
ZNF707 | zinc finger protein 707 | 0.013 | ||
ACSM1 | acyl-CoA synthetase medium-chain family member 1 | 0.012 | ||
PRPF4B | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 0.012 | ||
TRIM39 | tripartite motif containing 39 | 0.012 | ||
RPP14 | ribonuclease P/MRP 14kDa subunit | 0.012 | ||
SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) | 0.012 | ||
FAM82A2 | family with sequence similarity 82, member A2 | 0.012 | ||
RS1 | retinoschisin 1 | 0.012 | ||
ACO2 | aconitase 2, mitochondrial | 0.012 | ||
ABCA4 | ATP-binding cassette, sub-family A (ABC1), member 4 | 0.012 | ||
MFSD7 | major facilitator superfamily domain containing 7 | 0.012 | ||
IFNW1 | interferon, omega 1 | 0.012 | ||
SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.012 | ||
NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 0.012 | ||
NYX | nyctalopin | 0.012 | ||
MEX3B | mex-3 homolog B (C. elegans) | 0.012 | ||
RBM42 | RNA binding motif protein 42 | 0.012 | ||
TBL3 | transducin (beta)-like 3 | 0.012 | ||
MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) | 0.012 | ||
CLSPN | claspin | 0.012 | ||
THAP11 | THAP domain containing 11 | 0.011 | ||
RNF130 | ring finger protein 130 | 0.011 | ||
SLC6A13 | solute carrier family 6 (neurotransmitter transporter, GABA), member 13 | 0.011 | ||
BFSP2 | beaded filament structural protein 2, phakinin | 0.011 | ||
HEXIM1 | hexamethylene bis-acetamide inducible 1 | 0.011 | ||
CCDC57 | coiled-coil domain containing 57 | 0.011 | ||
ZNF267 | zinc finger protein 267 | 0.011 | ||
TBX6 | T-box 6 | 0.011 | ||
AANAT | aralkylamine N-acetyltransferase | 0.011 | ||
SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.011 | ||
MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | 0.011 | ||
POLR2C | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | 0.011 | ||
CDK20 | cyclin-dependent kinase 20 | 0.011 | ||
NOSIP | nitric oxide synthase interacting protein | 0.011 | ||
AMPD2 | adenosine monophosphate deaminase 2 | 0.011 | ||
DDX23 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 | 0.011 | ||
ANAPC11 | anaphase promoting complex subunit 11 | 0.011 | ||
SIGLEC15 | sialic acid binding Ig-like lectin 15 | 0.011 | ||
GUCA1B | guanylate cyclase activator 1B (retina) | 0.011 | ||
ZNF830 | zinc finger protein 830 | 0.011 | ||
SFTPD | surfactant protein D | 0.011 | ||
PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F | 0.011 | ||
MUSK | muscle, skeletal, receptor tyrosine kinase | 0.011 | ||
MFAP1 | microfibrillar-associated protein 1 | 0.011 | ||
U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.011 | ||
DIABLO | diablo, IAP-binding mitochondrial protein | 0.011 | ||
XIAP | X-linked inhibitor of apoptosis | 0.011 | ||
RNF38 | ring finger protein 38 | 0.011 | ||
UBAC1 | UBA domain containing 1 | 0.011 | ||
S1PR2 | sphingosine-1-phosphate receptor 2 | 0.011 | ||
PLXNB1 | plexin B1 | 0.011 | ||
PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.011 | ||
EDN3 | endothelin 3 | 0.011 | ||
GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 | 0.011 | ||
CTAG2 | cancer/testis antigen 2 | 0.011 | ||
GRK1 | G protein-coupled receptor kinase 1 | 0.011 | ||
TJP3 | tight junction protein 3 (zona occludens 3) | 0.011 | ||
SUCLG1 | succinate-CoA ligase, alpha subunit | 0.011 | ||
CHFR | checkpoint with forkhead and ring finger domains | 0.011 | ||
BFSP1 | beaded filament structural protein 1, filensin | 0.011 | ||
BIN1 | bridging integrator 1 | 0.011 | ||
ZNF670 | zinc finger protein 670 | 0.011 | ||
FAM126A | family with sequence similarity 126, member A | 0.011 | ||
MAGED1 | melanoma antigen family D, 1 | 0.011 | ||
SAMM50 | sorting and assembly machinery component 50 homolog (S. cerevisiae) | 0.011 | ||
CYP11B2 | cytochrome P450, family 11, subfamily B, polypeptide 2 | 0.011 | ||
TSKS | testis-specific serine kinase substrate | 0.010 | ||
DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.010 | ||
CNGB1 | cyclic nucleotide gated channel beta 1 | 0.010 | ||
OR3A3 | olfactory receptor, family 3, subfamily A, member 3 | 0.010 | ||
GPR44 | G protein-coupled receptor 44 | 0.010 | ||
PRKAB1 | protein kinase, AMP-activated, beta 1 non-catalytic subunit | 0.010 | ||
RENBP | renin binding protein | 0.010 | ||
GPHN | gephyrin | 0.010 | ||
CDKL2 | cyclin-dependent kinase-like 2 (CDC2-related kinase) | 0.010 | ||
PLEKHH3 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 | 0.010 | ||
LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 | 0.010 | ||
SIX1 | SIX homeobox 1 | 0.010 | ||
CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.010 | ||
CHRM5 | cholinergic receptor, muscarinic 5 | 0.010 | ||
SLC27A1 | solute carrier family 27 (fatty acid transporter), member 1 | 0.010 | ||
PRL | prolactin | 0.010 | ||
C7orf70 | chromosome 7 open reading frame 70 | 0.010 | ||
NRTN | neurturin | 0.010 | ||
KIF25 | kinesin family member 25 | 0.010 | ||
CCNT1 | cyclin T1 | 0.010 | ||
SOX3 | SRY (sex determining region Y)-box 3 | 0.010 | ||
GABRR1 | gamma-aminobutyric acid (GABA) receptor, rho 1 | 0.010 | ||
RHO | rhodopsin | 0.010 | ||
DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.010 | ||
BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 | 0.010 | ||
ADCY10 | adenylate cyclase 10 (soluble) | 0.010 | ||
ADAM20 | ADAM metallopeptidase domain 20 | 0.010 | ||
MFN2 | mitofusin 2 | 0.010 | ||
COQ9 | coenzyme Q9 homolog (S. cerevisiae) | 0.010 | ||
GUCA2B | guanylate cyclase activator 2B (uroguanylin) | 0.010 | ||
GHRHR | growth hormone releasing hormone receptor | 0.010 | ||
ZP2 | zona pellucida glycoprotein 2 (sperm receptor) | 0.010 | ||
PRX | periaxin | 0.010 | ||
SLC7A4 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 | 0.010 | Human | |
NRL | neural retina leucine zipper | 0.010 | ||
C22orf31 | chromosome 22 open reading frame 31 | 0.010 | ||
NDUFS2 | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 0.010 | ||
DHPS | deoxyhypusine synthase | 0.010 | ||
RPGR | retinitis pigmentosa GTPase regulator | 0.010 | ||
CRX | cone-rod homeobox | 0.010 | ||
PRPF4 | PRP4 pre-mRNA processing factor 4 homolog (yeast) | 0.009 | ||
RP2 | retinitis pigmentosa 2 (X-linked recessive) | 0.009 | ||
SAG | S-antigen; retina and pineal gland (arrestin) | 0.009 | ||
RP1 | retinitis pigmentosa 1 (autosomal dominant) | 0.009 | ||
NR2E3 | nuclear receptor subfamily 2, group E, member 3 | 0.008 | ||
TULP1 | tubby like protein 1 | 0.008 | ||
MAK | male germ cell-associated kinase | 0.008 | ||
PDE6A | phosphodiesterase 6A, cGMP-specific, rod, alpha | 0.008 | ||
RGR | retinal G protein coupled receptor | 0.008 | ||
SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.008 | ||
BEST1 | bestrophin 1 | 0.007 | ||
PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta | 0.007 | ||
RPE65 | retinal pigment epithelium-specific protein 65kDa | 0.007 | ||
CLRN1 | clarin 1 | 0.007 | ||
MERTK | c-mer proto-oncogene tyrosine kinase | 0.007 | ||
IMPG2 | interphotoreceptor matrix proteoglycan 2 | 0.007 | ||
ROM1 | retinal outer segment membrane protein 1 | 0.007 | ||
CNGA1 | cyclic nucleotide gated channel alpha 1 | 0.007 | ||
PRPH2 | peripherin 2 (retinal degeneration, slow) | 0.007 | ||
DHDDS | dehydrodolichyl diphosphate synthase | 0.007 | ||
FSCN2 | fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) | 0.007 | ||
CRB1 | crumbs homolog 1 (Drosophila) | 0.007 | ||
ZNF513 | zinc finger protein 513 | 0.007 | ||
PROM1 | prominin 1 | 0.007 | ||
CA4 | carbonic anhydrase IV | 0.006 | ||
EYS | eyes shut homolog (Drosophila) | 0.006 | ||
ARL2BP | ADP-ribosylation factor-like 2 binding protein | 0.006 | ||
RDH12 | retinol dehydrogenase 12 (all-trans/9-cis/11-cis) | 0.006 | ||
PRCD | progressive rod-cone degeneration | 0.005 | ||
IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 | 0.005 | ||
FAM161A | family with sequence similarity 161, member A | 0.005 | ||
PLK1S1 | polo-like kinase 1 substrate 1 | 0.005 | ||
SLC7A14 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 14 | 0.005 | ||
C2orf71 | chromosome 2 open reading frame 71 | 0.005 | ||
TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 0.005 | ||
CERKL | ceramide kinase-like | 0.003 | ||
IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | 0.002 | ||
KLHL7 | kelch-like 7 (Drosophila) | 0.002 |