IMP

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Homo sapiens

51 genes annotated in human

retinitis pigmentosa

DOID:10584

A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "retinitis pigmentosa"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "retinitis pigmentosa" (in gray)

Name	Description	Probability	Func Analog Organism
PRPF8	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	0.959
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.956
CD2BP2	CD2 (cytoplasmic tail) binding protein 2	0.789
PRPF6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	0.784
SF3B2	splicing factor 3b, subunit 2, 145kDa	0.739
PRPF31	PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)	0.679
C2orf65	chromosome 2 open reading frame 65	0.467
SART3	squamous cell carcinoma antigen recognized by T cells 3	0.435
SLU7	SLU7 splicing factor homolog (S. cerevisiae)	0.403
IK	IK cytokine, down-regulator of HLA II	0.329
SART1	squamous cell carcinoma antigen recognized by T cells	0.280
USP39	ubiquitin specific peptidase 39	0.232
SF3A2	splicing factor 3a, subunit 2, 66kDa	0.227
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.165
RNF113A	ring finger protein 113A	0.086
PHF5A	PHD finger protein 5A	0.082
CDK9	cyclin-dependent kinase 9	0.066
PLXND1	plexin D1	0.066
SRRM2	serine/arginine repetitive matrix 2	0.064
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.052
PPIH	peptidylprolyl isomerase H (cyclophilin H)	0.049
SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)	0.048
INADL	InaD-like (Drosophila)	0.045
CEP72	centrosomal protein 72kDa	0.042
SNRNP40	small nuclear ribonucleoprotein 40kDa (U5)	0.038
HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')	0.033
SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.031
PLXNB2	plexin B2	0.031
ARL3	ADP-ribosylation factor-like 3	0.029
MEPCE	methylphosphate capping enzyme	0.028
HUWE1	HECT, UBA and WWE domain containing 1	0.027
PFDN4	prefoldin subunit 4	0.026
BUD13	BUD13 homolog (S. cerevisiae)	0.026
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.026
PDE6D	phosphodiesterase 6D, cGMP-specific, rod, delta	0.026
TXNL4A	thioredoxin-like 4A	0.025
RBM4	RNA binding motif protein 4	0.025
MYBBP1A	MYB binding protein (P160) 1a	0.024
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.024
NSFL1C	NSFL1 (p97) cofactor (p47)	0.023
WBP11	WW domain binding protein 11	0.023
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.023
SMNDC1	survival motor neuron domain containing 1	0.023
GPKOW	G patch domain and KOW motifs	0.023
IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha	0.023
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.022
PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	0.021
HDAC3	histone deacetylase 3	0.021
PQBP1	polyglutamine binding protein 1	0.020
AKNA	AT-hook transcription factor	0.020
DHX16	DEAH (Asp-Glu-Ala-His) box polypeptide 16	0.020
PRPF3	PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)	0.019
WDR83	WD repeat domain 83	0.019
SLC25A3	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3	0.019
NAA38	N(alpha)-acetyltransferase 38, NatC auxiliary subunit	0.018
OXA1L	oxidase (cytochrome c) assembly 1-like	0.018
MMS19	MMS19 nucleotide excision repair homolog (S. cerevisiae)	0.018
MAX	MYC associated factor X	0.017
ARL2	ADP-ribosylation factor-like 2	0.017
TSR2	TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)	0.016
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.016
FBXW8	F-box and WD repeat domain containing 8	0.016
ARR3	arrestin 3, retinal (X-arrestin)	0.016	Human
RBM25	RNA binding motif protein 25	0.016
PCBP2	poly(rC) binding protein 2	0.016
C20orf43	chromosome 20 open reading frame 43	0.016
GFAP	glial fibrillary acidic protein	0.016
POLR3F	polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa	0.015
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.015
GOT2	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)	0.015
CRY1	cryptochrome 1 (photolyase-like)	0.015
SLC1A7	solute carrier family 1 (glutamate transporter), member 7	0.015
C20orf4	chromosome 20 open reading frame 4	0.015
BFAR	bifunctional apoptosis regulator	0.015
GMEB1	glucocorticoid modulatory element binding protein 1	0.015
MDFI	MyoD family inhibitor	0.015
GNAT1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	0.014
PDE6G	phosphodiesterase 6G, cGMP-specific, rod, gamma	0.014
PIGA	phosphatidylinositol glycan anchor biosynthesis, class A	0.014
ZNRF1	zinc and ring finger 1	0.014
NDUFV1	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa	0.014
FIZ1	FLT3-interacting zinc finger 1	0.014
ZCCHC7	zinc finger, CCHC domain containing 7	0.014
BCL10	B-cell CLL/lymphoma 10	0.013
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.013
ARFGAP2	ADP-ribosylation factor GTPase activating protein 2	0.013
HNF1A	HNF1 homeobox A	0.013
HADHA	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit	0.013
CDK5RAP1	CDK5 regulatory subunit associated protein 1	0.013
CAMK2D	calcium/calmodulin-dependent protein kinase II delta	0.013
ZNF707	zinc finger protein 707	0.013
ACSM1	acyl-CoA synthetase medium-chain family member 1	0.012
PRPF4B	PRP4 pre-mRNA processing factor 4 homolog B (yeast)	0.012
TRIM39	tripartite motif containing 39	0.012
RPP14	ribonuclease P/MRP 14kDa subunit	0.012
SMU1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)	0.012
FAM82A2	family with sequence similarity 82, member A2	0.012
RS1	retinoschisin 1	0.012
ACO2	aconitase 2, mitochondrial	0.012
ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4	0.012
MFSD7	major facilitator superfamily domain containing 7	0.012
IFNW1	interferon, omega 1	0.012
SIAH1	seven in absentia homolog 1 (Drosophila)	0.012
NDUFA10	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa	0.012
NYX	nyctalopin	0.012
MEX3B	mex-3 homolog B (C. elegans)	0.012
RBM42	RNA binding motif protein 42	0.012
TBL3	transducin (beta)-like 3	0.012
MPP5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.012
CLSPN	claspin	0.012
THAP11	THAP domain containing 11	0.011
RNF130	ring finger protein 130	0.011
SLC6A13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	0.011
BFSP2	beaded filament structural protein 2, phakinin	0.011
HEXIM1	hexamethylene bis-acetamide inducible 1	0.011
CCDC57	coiled-coil domain containing 57	0.011
ZNF267	zinc finger protein 267	0.011
TBX6	T-box 6	0.011
AANAT	aralkylamine N-acetyltransferase	0.011
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.011
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.011
POLR2C	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	0.011
CDK20	cyclin-dependent kinase 20	0.011
NOSIP	nitric oxide synthase interacting protein	0.011
AMPD2	adenosine monophosphate deaminase 2	0.011
DDX23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	0.011
ANAPC11	anaphase promoting complex subunit 11	0.011
SIGLEC15	sialic acid binding Ig-like lectin 15	0.011
GUCA1B	guanylate cyclase activator 1B (retina)	0.011
ZNF830	zinc finger protein 830	0.011
SFTPD	surfactant protein D	0.011
PPM1F	protein phosphatase, Mg2+/Mn2+ dependent, 1F	0.011
MUSK	muscle, skeletal, receptor tyrosine kinase	0.011
MFAP1	microfibrillar-associated protein 1	0.011
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.011
DIABLO	diablo, IAP-binding mitochondrial protein	0.011
XIAP	X-linked inhibitor of apoptosis	0.011
RNF38	ring finger protein 38	0.011
UBAC1	UBA domain containing 1	0.011
S1PR2	sphingosine-1-phosphate receptor 2	0.011
PLXNB1	plexin B1	0.011
PLEKHA5	pleckstrin homology domain containing, family A member 5	0.011
EDN3	endothelin 3	0.011
GNAT2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.011
CTAG2	cancer/testis antigen 2	0.011
GRK1	G protein-coupled receptor kinase 1	0.011
TJP3	tight junction protein 3 (zona occludens 3)	0.011
SUCLG1	succinate-CoA ligase, alpha subunit	0.011
CHFR	checkpoint with forkhead and ring finger domains	0.011
BFSP1	beaded filament structural protein 1, filensin	0.011
BIN1	bridging integrator 1	0.011
ZNF670	zinc finger protein 670	0.011
FAM126A	family with sequence similarity 126, member A	0.011
MAGED1	melanoma antigen family D, 1	0.011
SAMM50	sorting and assembly machinery component 50 homolog (S. cerevisiae)	0.011
CYP11B2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.011
TSKS	testis-specific serine kinase substrate	0.010
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.010
CNGB1	cyclic nucleotide gated channel beta 1	0.010
OR3A3	olfactory receptor, family 3, subfamily A, member 3	0.010
GPR44	G protein-coupled receptor 44	0.010
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.010
RENBP	renin binding protein	0.010
GPHN	gephyrin	0.010
CDKL2	cyclin-dependent kinase-like 2 (CDC2-related kinase)	0.010
PLEKHH3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3	0.010
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.010
SIX1	SIX homeobox 1	0.010
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.010
CHRM5	cholinergic receptor, muscarinic 5	0.010
SLC27A1	solute carrier family 27 (fatty acid transporter), member 1	0.010
PRL	prolactin	0.010
C7orf70	chromosome 7 open reading frame 70	0.010
NRTN	neurturin	0.010
KIF25	kinesin family member 25	0.010
CCNT1	cyclin T1	0.010
SOX3	SRY (sex determining region Y)-box 3	0.010
GABRR1	gamma-aminobutyric acid (GABA) receptor, rho 1	0.010
RHO	rhodopsin	0.010
DDX41	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41	0.010
BNIP1	BCL2/adenovirus E1B 19kDa interacting protein 1	0.010
ADCY10	adenylate cyclase 10 (soluble)	0.010
ADAM20	ADAM metallopeptidase domain 20	0.010
MFN2	mitofusin 2	0.010
COQ9	coenzyme Q9 homolog (S. cerevisiae)	0.010
GUCA2B	guanylate cyclase activator 2B (uroguanylin)	0.010
GHRHR	growth hormone releasing hormone receptor	0.010
ZP2	zona pellucida glycoprotein 2 (sperm receptor)	0.010
PRX	periaxin	0.010
SLC7A4	solute carrier family 7 (cationic amino acid transporter, y+ system), member 4	0.010	Human
NRL	neural retina leucine zipper	0.010
C22orf31	chromosome 22 open reading frame 31	0.010
NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)	0.010
DHPS	deoxyhypusine synthase	0.010
RPGR	retinitis pigmentosa GTPase regulator	0.010
CRX	cone-rod homeobox	0.010
PRPF4	PRP4 pre-mRNA processing factor 4 homolog (yeast)	0.009
RP2	retinitis pigmentosa 2 (X-linked recessive)	0.009
SAG	S-antigen; retina and pineal gland (arrestin)	0.009
RP1	retinitis pigmentosa 1 (autosomal dominant)	0.009
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.008
TULP1	tubby like protein 1	0.008
MAK	male germ cell-associated kinase	0.008
PDE6A	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.008
RGR	retinal G protein coupled receptor	0.008
SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A	0.008
BEST1	bestrophin 1	0.007
PDE6B	phosphodiesterase 6B, cGMP-specific, rod, beta	0.007
RPE65	retinal pigment epithelium-specific protein 65kDa	0.007
CLRN1	clarin 1	0.007
MERTK	c-mer proto-oncogene tyrosine kinase	0.007
IMPG2	interphotoreceptor matrix proteoglycan 2	0.007
ROM1	retinal outer segment membrane protein 1	0.007
CNGA1	cyclic nucleotide gated channel alpha 1	0.007
PRPH2	peripherin 2 (retinal degeneration, slow)	0.007
DHDDS	dehydrodolichyl diphosphate synthase	0.007
FSCN2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.007
CRB1	crumbs homolog 1 (Drosophila)	0.007
ZNF513	zinc finger protein 513	0.007
PROM1	prominin 1	0.007
CA4	carbonic anhydrase IV	0.006
EYS	eyes shut homolog (Drosophila)	0.006
ARL2BP	ADP-ribosylation factor-like 2 binding protein	0.006
RDH12	retinol dehydrogenase 12 (all-trans/9-cis/11-cis)	0.006
PRCD	progressive rod-cone degeneration	0.005
IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1	0.005
FAM161A	family with sequence similarity 161, member A	0.005
PLK1S1	polo-like kinase 1 substrate 1	0.005
SLC7A14	solute carrier family 7 (cationic amino acid transporter, y+ system), member 14	0.005
C2orf71	chromosome 2 open reading frame 71	0.005
TOPORS	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	0.005
CERKL	ceramide kinase-like	0.003
IDH3B	isocitrate dehydrogenase 3 (NAD+) beta	0.002
KLHL7	kelch-like 7 (Drosophila)	0.002