IMP
Process View
regulation of epidermal growth factor activated receptor activity
Any process that modulates the frequency, rate or extent of EGF-activated receptor activity.
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Click on a gene's description to view its network relationships with genes known to be involved in "regulation of epidermal growth factor activated receptor activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| EGFR | epidermal growth factor receptor | 0.977 | ||
| GRB2 | growth factor receptor-bound protein 2 | 0.957 | Fly | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.643 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.527 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.355 | ||
| ABI2 | abl-interactor 2 | 0.334 | ||
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.322 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.301 | Human Fly | |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.239 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.236 | ||
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.231 | ||
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.211 | ||
| ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.200 | ||
| EPOR | erythropoietin receptor | 0.170 | ||
| PSEN1 | presenilin 1 | 0.159 | Mouse | |
| MPDZ | multiple PDZ domain protein | 0.155 | ||
| FLNB | filamin B, beta | 0.122 | ||
| NCK1 | NCK adaptor protein 1 | 0.107 | ||
| SNX9 | sorting nexin 9 | 0.107 | ||
| GAB1 | GRB2-associated binding protein 1 | 0.096 | ||
| APP | amyloid beta (A4) precursor protein | 0.092 | Mouse | |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.086 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.086 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.086 | Human | |
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.075 | ||
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.075 | ||
| PLCG1 | phospholipase C, gamma 1 | 0.071 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.070 | ||
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.066 | ||
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.060 | ||
| CD28 | CD28 molecule | 0.053 | ||
| DNM1 | dynamin 1 | 0.049 | ||
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.046 | ||
| DLG4 | discs, large homolog 4 (Drosophila) | 0.046 | ||
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.045 | ||
| SH3D19 | SH3 domain containing 19 | 0.037 | ||
| CPD | carboxypeptidase D | 0.036 | ||
| SNX33 | sorting nexin 33 | 0.030 | ||
| LAT | linker for activation of T cells | 0.030 | ||
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.028 | ||
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.028 | ||
| DKK1 | dickkopf homolog 1 (Xenopus laevis) | 0.027 | ||
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.027 | ||
| GRB10 | growth factor receptor-bound protein 10 | 0.026 | ||
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.026 | ||
| SOCS2 | suppressor of cytokine signaling 2 | 0.026 | Human | |
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.026 | Mouse | |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.026 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.025 | ||
| JAK2 | Janus kinase 2 | 0.025 | ||
| PRKCA | protein kinase C, alpha | 0.023 | ||
| SH3GL2 | SH3-domain GRB2-like 2 | 0.022 | ||
| MUC1 | mucin 1, cell surface associated | 0.022 | ||
| SORBS3 | sorbin and SH3 domain containing 3 | 0.022 | ||
| SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.022 | ||
| SOCS3 | suppressor of cytokine signaling 3 | 0.020 | Human | |
| ADORA2A | adenosine A2a receptor | 0.020 | ||
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.020 | ||
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.020 | ||
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) | 0.020 | ||
| PKP4 | plakophilin 4 | 0.018 | ||
| SH3PXD2A | SH3 and PX domains 2A | 0.018 | ||
| AHNAK | AHNAK nucleoprotein | 0.018 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.017 | ||
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.017 | ||
| CAPRIN2 | caprin family member 2 | 0.017 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.017 | ||
| EGF | epidermal growth factor | 0.017 | ||
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.017 | ||
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.016 | ||
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.016 | ||
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.015 | ||
| KCNA1 | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 0.015 | ||
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.015 | ||
| TNS4 | tensin 4 | 0.015 | ||
| CCDC6 | coiled-coil domain containing 6 | 0.015 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.015 | ||
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.014 | ||
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.014 | ||
| APOE | apolipoprotein E | 0.014 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.014 | ||
| TRAF4 | TNF receptor-associated factor 4 | 0.014 | ||
| PTEN | phosphatase and tensin homolog | 0.014 | ||
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.014 | ||
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.014 | ||
| CMTM8 | CKLF-like MARVEL transmembrane domain containing 8 | 0.014 | ||
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.014 | ||
| TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.014 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.013 | ||
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.013 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.013 | ||
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.013 | ||
| CAV2 | caveolin 2 | 0.013 | ||
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 | 0.013 | ||
| DEDD | death effector domain containing | 0.013 | ||
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.013 | ||
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.012 | ||
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 | 0.012 | ||
| SSTR3 | somatostatin receptor 3 | 0.012 | ||
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.012 | ||
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 0.012 | ||
| CRY1 | cryptochrome 1 (photolyase-like) | 0.012 | ||
| PTPRA | protein tyrosine phosphatase, receptor type, A | 0.012 | ||
| WASL | Wiskott-Aldrich syndrome-like | 0.012 | ||
| SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 0.012 | ||
| COMMD1 | copper metabolism (Murr1) domain containing 1 | 0.012 | ||
| ABL2 | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.012 | ||
| NCK2 | NCK adaptor protein 2 | 0.012 | ||
| IRS4 | insulin receptor substrate 4 | 0.011 | ||
| ADAM10 | ADAM metallopeptidase domain 10 | 0.011 | ||
| AP2A1 | adaptor-related protein complex 2, alpha 1 subunit | 0.011 | ||
| NCSTN | nicastrin | 0.011 | ||
| IL12RB2 | interleukin 12 receptor, beta 2 | 0.011 | ||
| WNT3A | wingless-type MMTV integration site family, member 3A | 0.011 | ||
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.011 | ||
| LRP1 | low density lipoprotein receptor-related protein 1 | 0.011 | Human | |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | 0.011 | ||
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.011 | ||
| GAB2 | GRB2-associated binding protein 2 | 0.011 | ||
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.011 | ||
| CISH | cytokine inducible SH2-containing protein | 0.011 | Human | |
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.010 | ||
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.010 | ||
| ANXA1 | annexin A1 | 0.010 | ||
| MAP1S | microtubule-associated protein 1S | 0.010 | ||
| LCK | lymphocyte-specific protein tyrosine kinase | 0.010 |