IMP

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Homo sapiens

23 genes annotated in human

Multi-species View

negative regulation of viral transcription

GO:0032897

Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of viral transcription"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of viral transcription" (in gray)

Name	Description	Probability	Func Analog Organism
HDAC1	histone deacetylase 1	0.998
HDAC2	histone deacetylase 2	0.983	Human
IFITM1	interferon induced transmembrane protein 1 (9-27)	0.854	Human
JUN	jun proto-oncogene	0.847
CCL4	chemokine (C-C motif) ligand 4	0.736
IFITM2	interferon induced transmembrane protein 2 (1-8D)	0.706	Human
TRIM39	tripartite motif containing 39	0.702	Human
GFM1	G elongation factor, mitochondrial 1	0.701
CCR5	chemokine (C-C motif) receptor 5	0.648
SP1	Sp1 transcription factor	0.640
IFITM3	interferon induced transmembrane protein 3 (1-8U)	0.637
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.628
ATF3	activating transcription factor 3	0.626
MED15	mediator complex subunit 15	0.468
CXCL9	chemokine (C-X-C motif) ligand 9	0.384
SP110	SP110 nuclear body protein	0.360	Human
CCL5	chemokine (C-C motif) ligand 5	0.345
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.343
TRIM43	tripartite motif containing 43	0.328
IFI16	interferon, gamma-inducible protein 16	0.322
CCL2	chemokine (C-C motif) ligand 2	0.297	Human
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.249
PAX3	paired box 3	0.245
SOX10	SRY (sex determining region Y)-box 10	0.222
ESR1	estrogen receptor 1	0.206
FOXD3	forkhead box D3	0.134
CXCL10	chemokine (C-X-C motif) ligand 10	0.134
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.128
IFI44L	interferon-induced protein 44-like	0.126
CCL8	chemokine (C-C motif) ligand 8	0.123	Human
IER2	immediate early response 2	0.100
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.098
DPP4	dipeptidyl-peptidase 4	0.096
ZNF263	zinc finger protein 263	0.094
HCFC1	host cell factor C1 (VP16-accessory protein)	0.088
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.087
LIN28B	lin-28 homolog B (C. elegans)	0.086
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.086	Human
TRIM5	tripartite motif containing 5	0.080	Human
KDM6A	lysine (K)-specific demethylase 6A	0.079
SP100	SP100 nuclear antigen	0.078
DDIT3	DNA-damage-inducible transcript 3	0.078
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.074
CXCL11	chemokine (C-X-C motif) ligand 11	0.067
CCL22	chemokine (C-C motif) ligand 22	0.065	Human
TRIM21	tripartite motif containing 21	0.064
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.064
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.063
MX2	myxovirus (influenza virus) resistance 2 (mouse)	0.062
CCL3	chemokine (C-C motif) ligand 3	0.059
OCIAD1	OCIA domain containing 1	0.057
NCOR1	nuclear receptor corepressor 1	0.055
CCR7	chemokine (C-C motif) receptor 7	0.054
CCL7	chemokine (C-C motif) ligand 7	0.054	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.052
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.051
PML	promyelocytic leukemia	0.049
PLSCR1	phospholipid scramblase 1	0.046
CCL13	chemokine (C-C motif) ligand 13	0.045	Human
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.045
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.045
NAMPT	nicotinamide phosphoribosyltransferase	0.044
MAPK14	mitogen-activated protein kinase 14	0.044
RAB6A	RAB6A, member RAS oncogene family	0.044
IFNG	interferon, gamma	0.044
TRIM34	tripartite motif containing 34	0.043
DYDC1	DPY30 domain containing 1	0.042
IL1B	interleukin 1, beta	0.041
BST2	bone marrow stromal cell antigen 2	0.041
UBD	ubiquitin D	0.041
SOX2	SRY (sex determining region Y)-box 2	0.040
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.040
PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	0.039
ZNF473	zinc finger protein 473	0.038
TRIM22	tripartite motif containing 22	0.037	Human
RNF5	ring finger protein 5	0.037
TRIM63	tripartite motif containing 63	0.036	Human
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.035
CCR1	chemokine (C-C motif) receptor 1	0.035
SMAD4	SMAD family member 4	0.032
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.030
CCL19	chemokine (C-C motif) ligand 19	0.030	Human
RAB14	RAB14, member RAS oncogene family	0.029
NCL	nucleolin	0.029
IFI44	interferon-induced protein 44	0.028
VCAM1	vascular cell adhesion molecule 1	0.028
BCL6	B-cell CLL/lymphoma 6	0.028
SKIL	SKI-like oncogene	0.027
TRIM8	tripartite motif containing 8	0.027	Mouse
OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	0.026
TRIM38	tripartite motif containing 38	0.026	Human
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.026
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	0.026
GBP1	guanylate binding protein 1, interferon-inducible	0.026
MAGEA4	melanoma antigen family A, 4	0.024
XIAP	X-linked inhibitor of apoptosis	0.024
CCR4	chemokine (C-C motif) receptor 4	0.024
TOP1	topoisomerase (DNA) I	0.024
RBBP4	retinoblastoma binding protein 4	0.024
IL7R	interleukin 7 receptor	0.024
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.023
NMI	N-myc (and STAT) interactor	0.023
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.023
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.023
TRIM26	tripartite motif containing 26	0.022
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.022
SRGN	serglycin	0.022
BTN3A2	butyrophilin, subfamily 3, member A2	0.021
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.021
IL8	interleukin 8	0.020
TP53	tumor protein p53	0.020
TRIM17	tripartite motif containing 17	0.020	Human
IL10	interleukin 10	0.020
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.019
FPR3	formyl peptide receptor 3	0.019
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.019
CYorf15A	chromosome Y open reading frame 15A	0.019
TRIM52	tripartite motif containing 52	0.018
GBP2	guanylate binding protein 2, interferon-inducible	0.018
PHF11	PHD finger protein 11	0.018
RCOR1	REST corepressor 1	0.018
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.017
HLA-E	major histocompatibility complex, class I, E	0.017
C19orf66	chromosome 19 open reading frame 66	0.017
MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	0.016
RNF41	ring finger protein 41	0.015
HMOX2	heme oxygenase (decycling) 2	0.015
ELF1	E74-like factor 1 (ets domain transcription factor)	0.015
IL6	interleukin 6 (interferon, beta 2)	0.015
ICAM1	intercellular adhesion molecule 1	0.015
B2M	beta-2-microglobulin	0.015
TNF	tumor necrosis factor	0.015
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.015
TTN	titin	0.014
SMAD3	SMAD family member 3	0.014
CCL1	chemokine (C-C motif) ligand 1	0.014	Human
CD83	CD83 molecule	0.014
DZIP3	DAZ interacting protein 3, zinc finger	0.014
IL2RB	interleukin 2 receptor, beta	0.014
IDO1	indoleamine 2,3-dioxygenase 1	0.014
IL21R	interleukin 21 receptor	0.014
IRF2	interferon regulatory factor 2	0.014
JUND	jun D proto-oncogene	0.014	Human
DES	desmin	0.014
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.013
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.013
MCOLN1	mucolipin 1	0.013
IL15RA	interleukin 15 receptor, alpha	0.013
MYD88	myeloid differentiation primary response gene (88)	0.013
ABHD16A	abhydrolase domain containing 16A	0.013
RNF32	ring finger protein 32	0.013
IL2RG	interleukin 2 receptor, gamma	0.013
C1S	complement component 1, s subcomponent	0.013
IL1A	interleukin 1, alpha	0.013
LAMP3	lysosomal-associated membrane protein 3	0.013
BRAP	BRCA1 associated protein	0.013
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.013
RBBP7	retinoblastoma binding protein 7	0.013
GFI1B	growth factor independent 1B transcription repressor	0.013
HTT	huntingtin	0.013
MEOX2	mesenchyme homeobox 2	0.013
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.013
HMGA1	high mobility group AT-hook 1	0.012	Human
SP140L	SP140 nuclear body protein-like	0.012	Human
ADAMDEC1	ADAM-like, decysin 1	0.012
GLTPD1	glycolipid transfer protein domain containing 1	0.012
JDP2	Jun dimerization protein 2	0.012
SAMD9	sterile alpha motif domain containing 9	0.012
DDX3Y	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked	0.012
RNF126	ring finger protein 126	0.012
UTY	ubiquitously transcribed tetratricopeptide repeat gene, Y-linked	0.012
CREBZF	CREB/ATF bZIP transcription factor	0.012
FOSL1	FOS-like antigen 1	0.012
EBI3	Epstein-Barr virus induced 3	0.012
CLTC	clathrin, heavy chain (Hc)	0.011
NFYA	nuclear transcription factor Y, alpha	0.011
CH25H	cholesterol 25-hydroxylase	0.011
IRF2BP1	interferon regulatory factor 2 binding protein 1	0.011
RGS1	regulator of G-protein signaling 1	0.011
CCL17	chemokine (C-C motif) ligand 17	0.011	Human
SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	0.011
TRIM32	tripartite motif containing 32	0.011
STAT4	signal transducer and activator of transcription 4	0.011
SOX11	SRY (sex determining region Y)-box 11	0.011
FAS	Fas (TNF receptor superfamily, member 6)	0.011
PDE9A	phosphodiesterase 9A	0.010
BATF	basic leucine zipper transcription factor, ATF-like	0.010
RAB5A	RAB5A, member RAS oncogene family	0.010
IL1RN	interleukin 1 receptor antagonist	0.010
RNF181	ring finger protein 181	0.010
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.010
TRIM4	tripartite motif containing 4	0.010	Human