IMP

Process View

Homo sapiens

1 genes annotated in human

cochlea development

The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cochlea development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cochlea development" (in gray)

Name	Description	Probability	Func Analog Organism
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.881	Mouse
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.877	Mouse
CSNK1E	casein kinase 1, epsilon	0.860
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.854
BBS10	Bardet-Biedl syndrome 10	0.583
AXIN1	axin 1	0.462
CTNND1	catenin (cadherin-associated protein), delta 1	0.411
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.364
ZNF512B	zinc finger protein 512B	0.360
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.257
LRRK2	leucine-rich repeat kinase 2	0.229
CALCA	calcitonin-related polypeptide alpha	0.148
CEP164	centrosomal protein 164kDa	0.144
SH3RF3	SH3 domain containing ring finger 3	0.104
WT1	Wilms tumor 1	0.094
RHOA	ras homolog gene family, member A	0.089
PTK2	PTK2 protein tyrosine kinase 2	0.077
HES1	hairy and enhancer of split 1, (Drosophila)	0.076	Mouse
BAHD1	bromo adjacent homology domain containing 1	0.064
FGF1	fibroblast growth factor 1 (acidic)	0.063
LPXN	leupaxin	0.060
C9orf100	chromosome 9 open reading frame 100	0.059
DLG2	discs, large homolog 2 (Drosophila)	0.055
HOXA5	homeobox A5	0.051
TRIP6	thyroid hormone receptor interactor 6	0.049
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.047
ELF5	E74-like factor 5 (ets domain transcription factor)	0.045
EHF	ets homologous factor	0.045
CHN2	chimerin (chimaerin) 2	0.044
SH3RF1	SH3 domain containing ring finger 1	0.042
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.038
ATN1	atrophin 1	0.038
CSNK1D	casein kinase 1, delta	0.036
MCC	mutated in colorectal cancers	0.035
CTBP1	C-terminal binding protein 1	0.035
OCLN	occludin	0.034
JUP	junction plakoglobin	0.033
FAM110C	family with sequence similarity 110, member C	0.032
GLIS2	GLIS family zinc finger 2	0.032
PRKCA	protein kinase C, alpha	0.031
TAOK1	TAO kinase 1	0.030
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.030
MYST2	MYST histone acetyltransferase 2	0.030
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.029
C16orf48	chromosome 16 open reading frame 48	0.029
PRKCZ	protein kinase C, zeta	0.028
KRT8	keratin 8	0.028
RIPK4	receptor-interacting serine-threonine kinase 4	0.028
GTF3C1	general transcription factor IIIC, polypeptide 1, alpha 220kDa	0.025
BBS1	Bardet-Biedl syndrome 1	0.025
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.024
FAM110A	family with sequence similarity 110, member A	0.024
HOXA10	homeobox A10	0.023
PRPF3	PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)	0.023
FLNB	filamin B, beta	0.023
KLHL12	kelch-like 12 (Drosophila)	0.023
HOXA4	homeobox A4	0.022
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.022
TCF4	transcription factor 4	0.022
PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	0.022
PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	0.021
PSEN1	presenilin 1	0.021
TRAPPC6A	trafficking protein particle complex 6A	0.020
EYA2	eyes absent homolog 2 (Drosophila)	0.020
TIFA	TRAF-interacting protein with forkhead-associated domain	0.019
NKD2	naked cuticle homolog 2 (Drosophila)	0.019
PRNP	prion protein	0.019
SYN2	synapsin II	0.019
DPPA2	developmental pluripotency associated 2	0.019
HOXB6	homeobox B6	0.019
SIM2	single-minded homolog 2 (Drosophila)	0.019
CCNK	cyclin K	0.018
UNC5C	unc-5 homolog C (C. elegans)	0.018
CADM4	cell adhesion molecule 4	0.018
HOXB5	homeobox B5	0.018
PKNOX2	PBX/knotted 1 homeobox 2	0.018
PITX1	paired-like homeodomain 1	0.018
KLF5	Kruppel-like factor 5 (intestinal)	0.017
AP1M1	adaptor-related protein complex 1, mu 1 subunit	0.017
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.017
NCKIPSD	NCK interacting protein with SH3 domain	0.017
HOXA11	homeobox A11	0.017
HOXA7	homeobox A7	0.017
SNF8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.016
CCDC17	coiled-coil domain containing 17	0.016
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.016
EYA1	eyes absent homolog 1 (Drosophila)	0.016
ZMYND8	zinc finger, MYND-type containing 8	0.016
HOXD3	homeobox D3	0.016
RHOC	ras homolog gene family, member C	0.016
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.016
PTPRT	protein tyrosine phosphatase, receptor type, T	0.016
PAX3	paired box 3	0.015
MAP2K6	mitogen-activated protein kinase kinase 6	0.015
RIPK2	receptor-interacting serine-threonine kinase 2	0.015
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.015
PAX6	paired box 6	0.015
ARHGEF19	Rho guanine nucleotide exchange factor (GEF) 19	0.015
TNFAIP8L1	tumor necrosis factor, alpha-induced protein 8-like 1	0.015
HOXB7	homeobox B7	0.015
DAAM1	dishevelled associated activator of morphogenesis 1	0.015
PITX2	paired-like homeodomain 2	0.015
NRXN1	neurexin 1	0.014
GLP1R	glucagon-like peptide 1 receptor	0.014
INHBB	inhibin, beta B	0.014
MAP1B	microtubule-associated protein 1B	0.014
ARHGAP15	Rho GTPase activating protein 15	0.014
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.014
CHGB	chromogranin B (secretogranin 1)	0.014
PLEKHA7	pleckstrin homology domain containing, family A member 7	0.014
DDI1	DNA-damage inducible 1 homolog 1 (S. cerevisiae)	0.014
ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	0.014
ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	0.014
HOXB3	homeobox B3	0.014
PTPRF	protein tyrosine phosphatase, receptor type, F	0.014
LTK	leukocyte receptor tyrosine kinase	0.014
SOX11	SRY (sex determining region Y)-box 11	0.014
HOXC8	homeobox C8	0.014
NOTCH3	notch 3	0.013
ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	0.013
POU3F2	POU class 3 homeobox 2	0.013
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.013
SNTG2	syntrophin, gamma 2	0.013
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.013
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.013
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.013
SIX3	SIX homeobox 3	0.013
SEZ6L	seizure related 6 homolog (mouse)-like	0.013
TCEB3B	transcription elongation factor B polypeptide 3B (elongin A2)	0.013
RAB5B	RAB5B, member RAS oncogene family	0.013
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.013
FHOD1	formin homology 2 domain containing 1	0.013
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.013
GABRG3	gamma-aminobutyric acid (GABA) A receptor, gamma 3	0.013
HOXB9	homeobox B9	0.013
AQP1	aquaporin 1 (Colton blood group)	0.013
KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2	0.013
PNLIPRP1	pancreatic lipase-related protein 1	0.012
GRIA1	glutamate receptor, ionotropic, AMPA 1	0.012
JAG1	jagged 1	0.012
LEP	leptin	0.012
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.012
RGS6	regulator of G-protein signaling 6	0.012
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.012
NRG2	neuregulin 2	0.012
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.012
NEU4	sialidase 4	0.012
HOXA13	homeobox A13	0.012
CMTM8	CKLF-like MARVEL transmembrane domain containing 8	0.012
EMD	emerin	0.012
COL2A1	collagen, type II, alpha 1	0.012
FZD7	frizzled homolog 7 (Drosophila)	0.012
SORCS3	sortilin-related VPS10 domain containing receptor 3	0.012
SORBS3	sorbin and SH3 domain containing 3	0.012
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.012
FOXG1	forkhead box G1	0.012
SORBS2	sorbin and SH3 domain containing 2	0.012
BBS4	Bardet-Biedl syndrome 4	0.012
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.012
HAP1	huntingtin-associated protein 1	0.012
CAPN6	calpain 6	0.012
CTNNBIP1	catenin, beta interacting protein 1	0.012
ZNF165	zinc finger protein 165	0.012
HDAC6	histone deacetylase 6	0.012
PHKG1	phosphorylase kinase, gamma 1 (muscle)	0.012
ZNF408	zinc finger protein 408	0.012
OLIG2	oligodendrocyte lineage transcription factor 2	0.012
FAM83B	family with sequence similarity 83, member B	0.012
ACTL6B	actin-like 6B	0.012
PER1	period homolog 1 (Drosophila)	0.012
HMGA2	high mobility group AT-hook 2	0.012
FAM83H	family with sequence similarity 83, member H	0.012
LPHN3	latrophilin 3	0.012
CAMKV	CaM kinase-like vesicle-associated	0.012
CRIPAK	cysteine-rich PAK1 inhibitor	0.011
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.011
DBC1	deleted in bladder cancer 1	0.011
NOTCH1	notch 1	0.011
RET	ret proto-oncogene	0.011
HOXD10	homeobox D10	0.011
GAP43	growth associated protein 43	0.011
CA10	carbonic anhydrase X	0.011
PLSCR4	phospholipid scramblase 4	0.011
TRPC5	transient receptor potential cation channel, subfamily C, member 5	0.011
LRP4	low density lipoprotein receptor-related protein 4	0.011
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.011
NTF3	neurotrophin 3	0.011
LINGO1	leucine rich repeat and Ig domain containing 1	0.011
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.011
THAP11	THAP domain containing 11	0.011
CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.011
ZNF707	zinc finger protein 707	0.011
KRT17	keratin 17	0.011
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.011
GRIA3	glutamate receptor, ionotrophic, AMPA 3	0.011
UNKL	unkempt homolog (Drosophila)-like	0.011
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.011
CALCR	calcitonin receptor	0.011
GLDC	glycine dehydrogenase (decarboxylating)	0.011
HOXC9	homeobox C9	0.011
MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.011
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.011
DCX	doublecortin	0.011
CXADR	coxsackie virus and adenovirus receptor	0.011
TBX5	T-box 5	0.011
NDP	Norrie disease (pseudoglioma)	0.011
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.011
NGEF	neuronal guanine nucleotide exchange factor	0.011
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.011
FOXO3	forkhead box O3	0.011
SIX2	SIX homeobox 2	0.011
DIABLO	diablo, IAP-binding mitochondrial protein	0.011
FOXF2	forkhead box F2	0.011
ST8SIA3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.011
ARHGEF4	Rho guanine nucleotide exchange factor (GEF) 4	0.011
FOXD1	forkhead box D1	0.011
FAM124B	family with sequence similarity 124B	0.011
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.011
HOXA6	homeobox A6	0.011
MSX1	msh homeobox 1	0.011
PFN2	profilin 2	0.011
FNDC1	fibronectin type III domain containing 1	0.011
CDR1	cerebellar degeneration-related protein 1, 34kDa	0.011
MAGED1	melanoma antigen family D, 1	0.011
GPC4	glypican 4	0.011
ADCY8	adenylate cyclase 8 (brain)	0.011
CNTFR	ciliary neurotrophic factor receptor	0.011
PBX1	pre-B-cell leukemia homeobox 1	0.011
FGF9	fibroblast growth factor 9 (glia-activating factor)	0.011
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.011
OTX1	orthodenticle homeobox 1	0.011
EGF	epidermal growth factor	0.011
BMP7	bone morphogenetic protein 7	0.011
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.011
EMX1	empty spiracles homeobox 1	0.011
HOXC6	homeobox C6	0.011
COL12A1	collagen, type XII, alpha 1	0.010
ZNF331	zinc finger protein 331	0.010
PTK7	PTK7 protein tyrosine kinase 7	0.010	Mouse
AP3B2	adaptor-related protein complex 3, beta 2 subunit	0.010
COL11A1	collagen, type XI, alpha 1	0.010
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.010
FHL1	four and a half LIM domains 1	0.010
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.010
MAB21L1	mab-21-like 1 (C. elegans)	0.010
RGS2	regulator of G-protein signaling 2, 24kDa	0.010
DMRTB1	DMRT-like family B with proline-rich C-terminal, 1	0.010
MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	0.010
ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.010
AR	androgen receptor	0.010
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.010
APC2	adenomatosis polyposis coli 2	0.010
NXPH1	neurexophilin 1	0.010
BBS7	Bardet-Biedl syndrome 7	0.010
ESRP1	epithelial splicing regulatory protein 1	0.010
HSPB6	heat shock protein, alpha-crystallin-related, B6	0.010
PCDHA2	protocadherin alpha 2	0.010
PDZK1	PDZ domain containing 1	0.010
PPL	periplakin	0.010
RADIL	Ras association and DIL domains	0.010
PRKD1	protein kinase D1	0.010
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.010
FHOD3	formin homology 2 domain containing 3	0.010
HOXA2	homeobox A2	0.010	Human
ETV1	ets variant 1	0.010
HOXB4	homeobox B4	0.010
ADCY1	adenylate cyclase 1 (brain)	0.010
NTM	neurotrimin	0.010
HIC1	hypermethylated in cancer 1	0.010
PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	0.010
MEGF11	multiple EGF-like-domains 11	0.010
RYR2	ryanodine receptor 2 (cardiac)	0.010
FERMT2	fermitin family member 2	0.010
LHX2	LIM homeobox 2	0.010
STOX2	storkhead box 2	0.010
IRX5	iroquois homeobox 5	0.010
NELL1	NEL-like 1 (chicken)	0.010
TTC28	tetratricopeptide repeat domain 28	0.010
CDH19	cadherin 19, type 2	0.010
PCDHA9	protocadherin alpha 9	0.010
EN2	engrailed homeobox 2	0.010
ERC2	ELKS/RAB6-interacting/CAST family member 2	0.010
PMP2	peripheral myelin protein 2	0.010
SFRP1	secreted frizzled-related protein 1	0.010