IMP
Process View
negative regulation of rho protein signal transduction
Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of rho protein signal transduction"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Lama5 | laminin, alpha 5 | 0.924 | ||
| Itgb3 | integrin beta 3 | 0.881 | Mouse | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.870 | ||
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.800 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.792 | ||
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.787 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.637 | ||
| Itga3 | integrin alpha 3 | 0.625 | ||
| Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.540 | Mouse | |
| Vegfa | vascular endothelial growth factor A | 0.534 | ||
| Braf | Braf transforming gene | 0.507 | ||
| Apc | adenomatosis polyposis coli | 0.397 | ||
| Eng | endoglin | 0.387 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.360 | ||
| Pten | phosphatase and tensin homolog | 0.330 | ||
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.247 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.231 | ||
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.229 | ||
| Ric8 | resistance to inhibitors of cholinesterase 8 homolog (C. elegans) | 0.223 | ||
| Cd151 | CD151 antigen | 0.220 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.219 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.204 | ||
| Selp | selectin, platelet | 0.190 | ||
| Myo1f | myosin IF | 0.177 | ||
| Dok2 | docking protein 2 | 0.170 | ||
| Cd22 | CD22 antigen | 0.166 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.147 | ||
| Acvrl1 | activin A receptor, type II-like 1 | 0.125 | ||
| Kit | kit oncogene | 0.108 | ||
| Pdgfb | platelet derived growth factor, B polypeptide | 0.092 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.087 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.084 | ||
| Pcdh12 | protocadherin 12 | 0.079 | ||
| Adcy4 | adenylate cyclase 4 | 0.074 | ||
| Itga6 | integrin alpha 6 | 0.071 | Mouse | |
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.069 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.068 | ||
| Bcar1 | breast cancer anti-estrogen resistance 1 | 0.062 | ||
| Itgal | integrin alpha L | 0.060 | Mouse | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.059 | ||
| Aplnr | apelin receptor | 0.059 | ||
| Itga5 | integrin alpha 5 (fibronectin receptor alpha) | 0.058 | Mouse | |
| Fas | Fas (TNF receptor superfamily member 6) | 0.057 | ||
| Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.056 | ||
| Tln1 | talin 1 | 0.053 | ||
| Itgam | integrin alpha M | 0.051 | Mouse | |
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.049 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.049 | ||
| Trp63 | transformation related protein 63 | 0.048 | ||
| Sema6d | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 0.046 | ||
| Hbegf | heparin-binding EGF-like growth factor | 0.046 | ||
| Tbx21 | T-box 21 | 0.045 | ||
| Ets1 | E26 avian leukemia oncogene 1, 5' domain | 0.044 | ||
| Hlx | H2.0-like homeobox | 0.044 | ||
| Gja1 | gap junction protein, alpha 1 | 0.043 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.043 | ||
| Bcl6b | B-cell CLL/lymphoma 6, member B | 0.043 | Mouse | |
| Smad4 | MAD homolog 4 (Drosophila) | 0.041 | ||
| Nf1 | neurofibromatosis 1 | 0.041 | ||
| Dok1 | docking protein 1 | 0.041 | ||
| Abl2 | v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) | 0.041 | ||
| Wt1 | Wilms tumor 1 homolog | 0.040 | ||
| Mmp9 | matrix metallopeptidase 9 | 0.040 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.039 | ||
| Hmha1 | histocompatibility (minor) HA-1 | 0.037 | ||
| Ins2 | insulin II | 0.035 | ||
| Kif3a | kinesin family member 3A | 0.035 | ||
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.034 | ||
| Spn | sialophorin | 0.034 | ||
| Cdon | cell adhesion molecule-related/down-regulated by oncogenes | 0.033 | ||
| C5ar1 | complement component 5a receptor 1 | 0.032 | ||
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.032 | ||
| Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.032 | ||
| Kitl | kit ligand | 0.032 | ||
| Runx1 | runt related transcription factor 1 | 0.031 | ||
| Ggta1 | glycoprotein galactosyltransferase alpha 1, 3 | 0.029 | ||
| Rock2 | Rho-associated coiled-coil containing protein kinase 2 | 0.028 | ||
| Wasl | Wiskott-Aldrich syndrome-like (human) | 0.028 | ||
| Col4a3 | collagen, type IV, alpha 3 | 0.027 | ||
| Cdh5 | cadherin 5 | 0.026 | ||
| Flt4 | FMS-like tyrosine kinase 4 | 0.025 | ||
| Usp9x | ubiquitin specific peptidase 9, X chromosome | 0.025 | ||
| Tcf21 | transcription factor 21 | 0.025 | ||
| P2rx7 | purinergic receptor P2X, ligand-gated ion channel, 7 | 0.024 | ||
| Il18rap | interleukin 18 receptor accessory protein | 0.023 | ||
| Prdm1 | PR domain containing 1, with ZNF domain | 0.023 | ||
| Dlg1 | discs, large homolog 1 (Drosophila) | 0.023 | ||
| Tgfbr1 | transforming growth factor, beta receptor I | 0.023 | ||
| S1pr4 | sphingosine-1-phosphate receptor 4 | 0.022 | ||
| Cnr2 | cannabinoid receptor 2 (macrophage) | 0.022 | ||
| Klrb1b | killer cell lectin-like receptor subfamily B member 1B | 0.022 | ||
| Nkx2-1 | NK2 homeobox 1 | 0.022 | ||
| Efnb2 | ephrin B2 | 0.021 | ||
| Plec | plectin | 0.021 | ||
| Tbxas1 | thromboxane A synthase 1, platelet | 0.020 | ||
| Pxn | paxillin | 0.020 | ||
| Ppard | peroxisome proliferator activator receptor delta | 0.020 | ||
| Prkci | protein kinase C, iota | 0.019 | ||
| Egfr | epidermal growth factor receptor | 0.019 | ||
| Csf3r | colony stimulating factor 3 receptor (granulocyte) | 0.019 | ||
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.019 | ||
| Gna15 | guanine nucleotide binding protein, alpha 15 | 0.018 | ||
| Lepr | leptin receptor | 0.018 | ||
| Il10ra | interleukin 10 receptor, alpha | 0.017 | ||
| Ear2 | eosinophil-associated, ribonuclease A family, member 2 | 0.017 | ||
| Lyst | lysosomal trafficking regulator | 0.017 | ||
| Mrc2 | mannose receptor, C type 2 | 0.017 | ||
| Col12a1 | collagen, type XII, alpha 1 | 0.017 | ||
| Cxcr3 | chemokine (C-X-C motif) receptor 3 | 0.017 | ||
| Batf | basic leucine zipper transcription factor, ATF-like | 0.016 | ||
| Def6 | differentially expressed in FDCP 6 | 0.016 | ||
| Prkar2a | protein kinase, cAMP dependent regulatory, type II alpha | 0.016 | ||
| Cdh6 | cadherin 6 | 0.016 | ||
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.016 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.015 | ||
| Spry4 | sprouty homolog 4 (Drosophila) | 0.015 | ||
| Fli1 | Friend leukemia integration 1 | 0.015 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.014 | ||
| Ret | ret proto-oncogene | 0.014 | ||
| Erbb2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.014 | ||
| Cd180 | CD180 antigen | 0.014 | ||
| Fermt2 | fermitin family homolog 2 (Drosophila) | 0.014 | ||
| Fgf2 | fibroblast growth factor 2 | 0.014 | ||
| Il27ra | interleukin 27 receptor, alpha | 0.014 | ||
| Lamc1 | laminin, gamma 1 | 0.014 | ||
| Nfe2 | nuclear factor, erythroid derived 2 | 0.014 | ||
| Apoe | apolipoprotein E | 0.013 | ||
| Rrm2b | ribonucleotide reductase M2 B (TP53 inducible) | 0.013 | ||
| Cd97 | CD97 antigen | 0.013 | ||
| Mcam | melanoma cell adhesion molecule | 0.013 | ||
| Gm14548 | predicted gene 14548 | 0.013 | ||
| Ushbp1 | Usher syndrome 1C binding protein 1 | 0.013 | ||
| Ncr1 | natural cytotoxicity triggering receptor 1 | 0.013 | ||
| Gcnt2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme | 0.013 | ||
| Impad1 | inositol monophosphatase domain containing 1 | 0.013 | ||
| Fgr | Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | 0.013 | ||
| Psen1 | presenilin 1 | 0.013 | ||
| Gp5 | glycoprotein 5 (platelet) | 0.013 | ||
| Pik3cg | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 0.012 | ||
| Gp9 | glycoprotein 9 (platelet) | 0.012 | ||
| S1pr3 | sphingosine-1-phosphate receptor 3 | 0.012 | ||
| Cd38 | CD38 antigen | 0.012 | ||
| Cd40 | CD40 antigen | 0.012 | ||
| Tnks1bp1 | tankyrase 1 binding protein 1 | 0.012 | ||
| Hic1 | hypermethylated in cancer 1 | 0.012 | ||
| Bmpr2 | bone morphogenic protein receptor, type II (serine/threonine kinase) | 0.012 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.012 | ||
| Bmi1 | Bmi1 polycomb ring finger oncogene | 0.012 | ||
| Lmna | lamin A | 0.012 | ||
| Lyl1 | lymphoblastomic leukemia 1 | 0.012 | ||
| Fgd3 | FYVE, RhoGEF and PH domain containing 3 | 0.012 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.012 | ||
| Nos2 | nitric oxide synthase 2, inducible | 0.012 | ||
| Map4k1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.012 | ||
| Fes | feline sarcoma oncogene | 0.012 | ||
| Dll1 | delta-like 1 (Drosophila) | 0.011 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.011 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.011 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.011 | ||
| Was | Wiskott-Aldrich syndrome homolog (human) | 0.011 | ||
| Pstpip1 | proline-serine-threonine phosphatase-interacting protein 1 | 0.011 | ||
| Bmp5 | bone morphogenetic protein 5 | 0.011 | ||
| Nckap1l | NCK associated protein 1 like | 0.011 | ||
| Xiap | X-linked inhibitor of apoptosis | 0.011 | ||
| Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.011 | ||
| Plcb3 | phospholipase C, beta 3 | 0.011 | ||
| Thbs1 | thrombospondin 1 | 0.011 | ||
| Sh3bp1 | SH3-domain binding protein 1 | 0.010 | ||
| Trp53 | transformation related protein 53 | 0.010 |