IMP
Process View
positive regulation of mitochondrial membrane permeability involved in apoptotic process
Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of mitochondrial membrane permeability involved in apoptotic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Bax | BCL2-associated X protein | 1.000 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 1.000 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 1.000 | Mouse | |
| Mcl1 | myeloid cell leukemia sequence 1 | 0.996 | Mouse | |
| Bak1 | BCL2-antagonist/killer 1 | 0.994 | Mouse | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.986 | ||
| Trp53 | transformation related protein 53 | 0.980 | ||
| Bcl2l1 | BCL2-like 1 | 0.971 | Mouse | |
| Pmaip1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.943 | ||
| Axin1 | axin 1 | 0.868 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.862 | ||
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.781 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.646 | ||
| Pdcd6ip | programmed cell death 6 interacting protein | 0.630 | ||
| Sharpin | SHANK-associated RH domain interacting protein | 0.617 | ||
| Ppp1cc | protein phosphatase 1, catalytic subunit, gamma isoform | 0.465 | ||
| Igh | immunoglobulin heavy chain complex | 0.458 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.434 | ||
| Kit | kit oncogene | 0.379 | ||
| Mta1 | metastasis associated 1 | 0.337 | ||
| Lyst | lysosomal trafficking regulator | 0.317 | ||
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.275 | ||
| Wt1 | Wilms tumor 1 homolog | 0.273 | ||
| Prrx1 | paired related homeobox 1 | 0.267 | ||
| Foxg1 | forkhead box G1 | 0.252 | ||
| Six2 | sine oculis-related homeobox 2 homolog (Drosophila) | 0.216 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.214 | ||
| Apc | adenomatosis polyposis coli | 0.165 | ||
| Bmf | BCL2 modifying factor | 0.162 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.150 | ||
| Bbc3 | BCL2 binding component 3 | 0.147 | ||
| Acadm | acyl-Coenzyme A dehydrogenase, medium chain | 0.138 | ||
| Atxn2 | ataxin 2 | 0.122 | ||
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.116 | ||
| Mtor | mechanistic target of rapamycin (serine/threonine kinase) | 0.116 | ||
| Pax2 | paired box gene 2 | 0.110 | ||
| Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.106 | ||
| Prkci | protein kinase C, iota | 0.105 | ||
| Mfn2 | mitofusin 2 | 0.090 | ||
| Ehd3 | EH-domain containing 3 | 0.088 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.088 | ||
| Mapk1 | mitogen-activated protein kinase 1 | 0.080 | ||
| Bid | BH3 interacting domain death agonist | 0.077 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.072 | ||
| Rara | retinoic acid receptor, alpha | 0.071 | ||
| Prrx2 | paired related homeobox 2 | 0.058 | ||
| Mapk9 | mitogen-activated protein kinase 9 | 0.054 | ||
| Galk1 | galactokinase 1 | 0.049 | ||
| Traf3ip2 | TRAF3 interacting protein 2 | 0.046 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.045 | ||
| Bach1 | BTB and CNC homology 1 | 0.044 | ||
| Pgam1 | phosphoglycerate mutase 1 | 0.043 | ||
| Ednra | endothelin receptor type A | 0.043 | ||
| Sox2 | SRY-box containing gene 2 | 0.043 | ||
| Ech1 | enoyl coenzyme A hydratase 1, peroxisomal | 0.043 | ||
| Klf6 | Kruppel-like factor 6 | 0.041 | ||
| Rps27l | ribosomal protein S27-like | 0.040 | ||
| 2700094K13Rik | RIKEN cDNA 2700094K13 gene | 0.040 | ||
| Atf3 | activating transcription factor 3 | 0.039 | ||
| Tbx1 | T-box 1 | 0.037 | ||
| Rpgrip1l | Rpgrip1-like | 0.037 | ||
| Mapk8 | mitogen-activated protein kinase 8 | 0.035 | ||
| Cd151 | CD151 antigen | 0.035 | ||
| Epn1 | epsin 1 | 0.034 | ||
| Alad | aminolevulinate, delta-, dehydratase | 0.034 | ||
| Mapk14 | mitogen-activated protein kinase 14 | 0.034 | ||
| Ern1 | endoplasmic reticulum (ER) to nucleus signalling 1 | 0.034 | ||
| Gsk3a | glycogen synthase kinase 3 alpha | 0.033 | ||
| Pgk1 | phosphoglycerate kinase 1 | 0.032 | ||
| Gdnf | glial cell line derived neurotrophic factor | 0.032 | ||
| Rarb | retinoic acid receptor, beta | 0.031 | ||
| Nr2c2 | nuclear receptor subfamily 2, group C, member 2 | 0.029 | ||
| Braf | Braf transforming gene | 0.029 | ||
| Dlx5 | distal-less homeobox 5 | 0.028 | ||
| Ccnd1 | cyclin D1 | 0.027 | ||
| Msx1 | homeobox, msh-like 1 | 0.026 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.025 | ||
| Tbx10 | T-box 10 | 0.025 | ||
| Hoxa3 | homeobox A3 | 0.024 | ||
| Rrm2b | ribonucleotide reductase M2 B (TP53 inducible) | 0.024 | ||
| Tax1bp3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.024 | ||
| Dusp1 | dual specificity phosphatase 1 | 0.024 | ||
| Gstz1 | glutathione transferase zeta 1 (maleylacetoacetate isomerase) | 0.023 | ||
| Usp9x | ubiquitin specific peptidase 9, X chromosome | 0.023 | ||
| Dach1 | dachshund 1 (Drosophila) | 0.023 | ||
| Dnm1 | dynamin 1 | 0.023 | ||
| Klf4 | Kruppel-like factor 4 (gut) | 0.022 | ||
| Lrrk2 | leucine-rich repeat kinase 2 | 0.022 | ||
| Arpc4 | actin related protein 2/3 complex, subunit 4 | 0.022 | ||
| Ep300 | E1A binding protein p300 | 0.022 | ||
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.021 | ||
| Rabep1 | rabaptin, RAB GTPase binding effector protein 1 | 0.021 | ||
| Hoxa2 | homeobox A2 | 0.021 | ||
| Casp3 | caspase 3 | 0.021 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.021 | ||
| Ehd4 | EH-domain containing 4 | 0.021 | ||
| Nans | N-acetylneuraminic acid synthase (sialic acid synthase) | 0.020 | ||
| Ppp1ca | protein phosphatase 1, catalytic subunit, alpha isoform | 0.020 | ||
| Dlx2 | distal-less homeobox 2 | 0.020 | ||
| Tcrd | T-cell receptor delta chain | 0.020 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.019 | ||
| Tomm20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.019 | ||
| Maff | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) | 0.019 | ||
| Acd | adrenocortical dysplasia | 0.019 | ||
| Tnfsf9 | tumor necrosis factor (ligand) superfamily, member 9 | 0.019 | ||
| Rnf111 | ring finger 111 | 0.019 | ||
| Skil | SKI-like | 0.018 | ||
| Ier2 | immediate early response 2 | 0.018 | ||
| Tcrb | T-cell receptor beta chain | 0.018 | ||
| Echs1 | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 0.018 | ||
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.018 | ||
| Mapk11 | mitogen-activated protein kinase 11 | 0.018 | ||
| Dlx1 | distal-less homeobox 1 | 0.017 | ||
| Kif1b | kinesin family member 1B | 0.017 | ||
| Sertad1 | SERTA domain containing 1 | 0.017 | ||
| Ret | ret proto-oncogene | 0.017 | ||
| Bcl2a1a | B-cell leukemia/lymphoma 2 related protein A1a | 0.017 | Mouse | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.016 | ||
| Wrn | Werner syndrome homolog (human) | 0.016 | ||
| Tecr | trans-2,3-enoyl-CoA reductase | 0.016 | ||
| Etfa | electron transferring flavoprotein, alpha polypeptide | 0.016 | ||
| Wdr26 | WD repeat domain 26 | 0.016 | ||
| Ikzf3 | IKAROS family zinc finger 3 | 0.016 | ||
| Rbck1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.016 | ||
| Nphp1 | nephronophthisis 1 (juvenile) homolog (human) | 0.015 | ||
| Hadha | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 0.015 | ||
| Foxi3 | forkhead box I3 | 0.015 | ||
| Btrc | beta-transducin repeat containing protein | 0.015 | ||
| Lef1 | lymphoid enhancer binding factor 1 | 0.015 | ||
| Hist1h1c | histone cluster 1, H1c | 0.015 | ||
| Atp5b | ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit | 0.015 | ||
| Rps6ka5 | ribosomal protein S6 kinase, polypeptide 5 | 0.014 | ||
| Tshz1 | teashirt zinc finger family member 1 | 0.013 | ||
| Nphs1 | nephrosis 1 homolog, nephrin (human) | 0.013 | ||
| Nubp1 | nucleotide binding protein 1 | 0.013 | ||
| Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.013 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.013 | ||
| Ugp2 | UDP-glucose pyrophosphorylase 2 | 0.013 | ||
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.013 | ||
| Pmm1 | phosphomannomutase 1 | 0.013 | ||
| Irf8 | interferon regulatory factor 8 | 0.013 | ||
| Prkar1a | protein kinase, cAMP dependent regulatory, type I, alpha | 0.013 | ||
| Midn | midnolin | 0.013 | ||
| Ccnd3 | cyclin D3 | 0.012 | ||
| Fos | FBJ osteosarcoma oncogene | 0.012 | ||
| Clybl | citrate lyase beta like | 0.012 | ||
| Atp5g3 | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) | 0.012 | ||
| Nampt | nicotinamide phosphoribosyltransferase | 0.012 | ||
| Cdk4 | cyclin-dependent kinase 4 | 0.012 | ||
| Xrn1 | 5'-3' exoribonuclease 1 | 0.012 | ||
| Nsd1 | nuclear receptor-binding SET-domain protein 1 | 0.012 | ||
| Id1 | inhibitor of DNA binding 1 | 0.011 | ||
| Dusp6 | dual specificity phosphatase 6 | 0.011 | ||
| Clic1 | chloride intracellular channel 1 | 0.011 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.011 | ||
| Nt5c | 5',3'-nucleotidase, cytosolic | 0.011 | ||
| Pxn | paxillin | 0.011 | ||
| Tjap1 | tight junction associated protein 1 | 0.011 | ||
| Ctnnd1 | catenin (cadherin associated protein), delta 1 | 0.011 | ||
| Tsc2 | tuberous sclerosis 2 | 0.010 | ||
| Becn1 | beclin 1, autophagy related | 0.010 | ||
| Pik3r2 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) | 0.010 | ||
| Dennd1a | DENN/MADD domain containing 1A | 0.010 | ||
| Nefl | neurofilament, light polypeptide | 0.010 | ||
| Mafk | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) | 0.010 |