IMP

Process View

Mus musculus

8 genes annotated in mouse

regulation of dna dependent dna replication

Any process that modulates the rate, frequency, or extent of DNA-dependent DNA replication, the process in which new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of dna dependent dna replication"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of dna dependent dna replication" (in gray)

Name	Description	Probability	Func Analog Organism
Mapk14	mitogen-activated protein kinase 14	0.950	Yeast
Mecp2	methyl CpG binding protein 2	0.735
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.725
Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)	0.528
Atf2	activating transcription factor 2	0.486
Ccna2	cyclin A2	0.459
Atm	ataxia telangiectasia mutated homolog (human)	0.377
Foxc1	forkhead box C1	0.339
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.309
Prc1	protein regulator of cytokinesis 1	0.262
Brca1	breast cancer 1	0.241
Kif11	kinesin family member 11	0.205
Zic3	zinc finger protein of the cerebellum 3	0.174
Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.169
Stag2	stromal antigen 2	0.167	Human
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.158
Cdk4	cyclin-dependent kinase 4	0.154
Ncaph	non-SMC condensin I complex, subunit H	0.143
Mapkapk2	MAP kinase-activated protein kinase 2	0.137
Pola1	polymerase (DNA directed), alpha 1	0.107
Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)	0.103
Mki67	antigen identified by monoclonal antibody Ki 67	0.100
Cdt1	chromatin licensing and DNA replication factor 1	0.099
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.097
Tcf19	transcription factor 19	0.095
Ccnb1	cyclin B1	0.094
Rad51ap1	RAD51 associated protein 1	0.092
Mapk11	mitogen-activated protein kinase 11	0.088	Yeast
Ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.086
Cdk1	cyclin-dependent kinase 1	0.079	Yeast Mouse
Cdca7l	cell division cycle associated 7 like	0.067
Cdca5	cell division cycle associated 5	0.065
Cdca8	cell division cycle associated 8	0.063
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.061
Bmp7	bone morphogenetic protein 7	0.060
Ctcf	CCCTC-binding factor	0.060
Rnf220	ring finger protein 220	0.058
Aurkb	aurora kinase B	0.053
Kdm5b	lysine (K)-specific demethylase 5B	0.053
Mdm2	transformed mouse 3T3 cell double minute 2	0.051
Ccnb2	cyclin B2	0.050
Suds3	suppressor of defective silencing 3 homolog (S. cerevisiae)	0.049
Ccne1	cyclin E1	0.048
Hells	helicase, lymphoid specific	0.045
Dtl	denticleless homolog (Drosophila)	0.043
Kif2a	kinesin family member 2A	0.043
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.039
Dna2	DNA replication helicase 2 homolog (yeast)	0.039
Mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.037
Timeless	timeless homolog (Drosophila)	0.037
Orc1	origin recognition complex, subunit 1	0.035
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.035
Rad50	RAD50 homolog (S. cerevisiae)	0.034
Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	0.033	Yeast
Mapk8	mitogen-activated protein kinase 8	0.032	Yeast
Rrm2	ribonucleotide reductase M2	0.032
Mapk1	mitogen-activated protein kinase 1	0.031
Hdac1	histone deacetylase 1	0.031
Rad51	RAD51 homolog (S. cerevisiae)	0.031
Pou5f1	POU domain, class 5, transcription factor 1	0.030
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.030
Cdca7	cell division cycle associated 7	0.030
Smc2	structural maintenance of chromosomes 2	0.029
Otx2	orthodenticle homolog 2 (Drosophila)	0.029
E2f8	E2F transcription factor 8	0.028
Atp11c	ATPase, class VI, type 11C	0.028
Kif22	kinesin family member 22	0.028
Plk4	polo-like kinase 4 (Drosophila)	0.025
Brca2	breast cancer 2	0.024
Msh2	mutS homolog 2 (E. coli)	0.024
Plk1	polo-like kinase 1 (Drosophila)	0.024
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.023
Ccnf	cyclin F	0.023
Pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.023
Rad21	RAD21 homolog (S. pombe)	0.023
Trp53	transformation related protein 53	0.022
Lig1	ligase I, DNA, ATP-dependent	0.022
Ttk	Ttk protein kinase	0.022
H2afx	H2A histone family, member X	0.022
Mis18bp1	MIS18 binding protein 1	0.021
Smc4	structural maintenance of chromosomes 4	0.020
Dyrk1a	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a	0.020
Chek1	checkpoint kinase 1 homolog (S. pombe)	0.020
Kif2c	kinesin family member 2C	0.019
Fmr1	fragile X mental retardation syndrome 1 homolog	0.019
Tk1	thymidine kinase 1	0.019
Rbl1	retinoblastoma-like 1 (p107)	0.018
Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.018
Trip13	thyroid hormone receptor interactor 13	0.018
Prkce	protein kinase C, epsilon	0.018
Lmnb1	lamin B1	0.017
Zfp644	zinc finger protein 644	0.017
Otud4	OTU domain containing 4	0.017
Kif23	kinesin family member 23	0.017
Mdm4	transformed mouse 3T3 cell double minute 4	0.016
Smc1a	structural maintenance of chromosomes 1A	0.016	Human
Sass6	spindle assembly 6 homolog (C. elegans)	0.016
Kif4	kinesin family member 4	0.015
Top2a	topoisomerase (DNA) II alpha	0.015	Yeast
Nbn	nibrin	0.015
Rrm1	ribonucleotide reductase M1	0.015
Prkd3	protein kinase D3	0.015
Meox2	mesenchyme homeobox 2	0.015
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.014
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.014
Pole	polymerase (DNA directed), epsilon	0.014
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.014
Klc1	kinesin light chain 1	0.014
Pten	phosphatase and tensin homolog	0.014
Stag1	stromal antigen 1	0.014
Smad2	MAD homolog 2 (Drosophila)	0.013
Sin3a	transcriptional regulator, SIN3A (yeast)	0.013	Yeast
Smc3	structural maintenace of chromosomes 3	0.013	Human
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.013
Stil	Scl/Tal1 interrupting locus	0.013
Cdc45	cell division cycle 45 homolog (S. cerevisiae)	0.013
Prim2	DNA primase, p58 subunit	0.013
E2f1	E2F transcription factor 1	0.012
Mybl2	myeloblastosis oncogene-like 2	0.011
Rmnd5a	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	0.011
Ccdc99	coiled-coil domain containing 99	0.011
Anln	anillin, actin binding protein	0.011
Cdk2	cyclin-dependent kinase 2	0.011
Ilf3	interleukin enhancer binding factor 3	0.011
Mms22l	MMS22-like, DNA repair protein	0.011
Ckap2	cytoskeleton associated protein 2	0.011
Ttc3	tetratricopeptide repeat domain 3	0.011
Nasp	nuclear autoantigenic sperm protein (histone-binding)	0.011
Racgap1	Rac GTPase-activating protein 1	0.010
Lims1	LIM and senescent cell antigen-like domains 1	0.010
Mta1	metastasis associated 1	0.010
Tmpo	thymopoietin	0.010
Chaf1b	chromatin assembly factor 1, subunit B (p60)	0.010
Hmbs	hydroxymethylbilane synthase	0.010
Sp1	trans-acting transcription factor 1	0.010
Birc5	baculoviral IAP repeat-containing 5	0.010
Rybp	RING1 and YY1 binding protein	0.010