IMP

Process View

Mus musculus

4 genes annotated in mouse

left lung development

The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "left lung development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "left lung development" (in gray)

Name	Description	Probability	Func Analog Organism
Bmp7	bone morphogenetic protein 7	1.000	Mouse
Gli3	GLI-Kruppel family member GLI3	1.000
Fgfr2	fibroblast growth factor receptor 2	1.000
Bmp4	bone morphogenetic protein 4	1.000
Shh	sonic hedgehog	0.999
Foxc1	forkhead box C1	0.998
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.983
Pitx2	paired-like homeodomain transcription factor 2	0.982
Hand1	heart and neural crest derivatives expressed transcript 1	0.974
Msx2	homeobox, msh-like 2	0.962
Sox9	SRY-box containing gene 9	0.959
Fgf8	fibroblast growth factor 8	0.947
Nodal	nodal	0.946
Foxh1	forkhead box H1	0.938
Fgfr3	fibroblast growth factor receptor 3	0.929
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.911
Msx1	homeobox, msh-like 1	0.882
Gli2	GLI-Kruppel family member GLI2	0.869
Prrx1	paired related homeobox 1	0.853
Foxc2	forkhead box C2	0.815
Smo	smoothened homolog (Drosophila)	0.802
Pax3	paired box gene 3	0.736
Runx2	runt related transcription factor 2	0.734
Hand2	heart and neural crest derivatives expressed transcript 2	0.705
Tbx15	T-box 15	0.670
Tbx3	T-box 3	0.635
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.619
Tgfb2	transforming growth factor, beta 2	0.567
Alx4	aristaless-like homeobox 4	0.554
Otx2	orthodenticle homolog 2 (Drosophila)	0.503
Tcfap2a	transcription factor AP-2, alpha	0.428
Gata4	GATA binding protein 4	0.419
Tbx1	T-box 1	0.412
Gata5	GATA binding protein 5	0.380
Lmx1b	LIM homeobox transcription factor 1 beta	0.357
Wnt5a	wingless-related MMTV integration site 5A	0.354
Hoxd13	homeobox D13	0.353
Meox2	mesenchyme homeobox 2	0.337
Lefty1	left right determination factor 1	0.314
Pitx1	paired-like homeodomain transcription factor 1	0.304	Mouse
Nog	noggin	0.297
Gsc	goosecoid homeobox	0.296
Gdf1	growth differentiation factor 1	0.295
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.256
Chrd	chordin	0.243
Zic3	zinc finger protein of the cerebellum 3	0.240
Col2a1	collagen, type II, alpha 1	0.205
Lhx1	LIM homeobox protein 1	0.198
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.192
Col13a1	collagen, type XIII, alpha 1	0.189
Pthlh	parathyroid hormone-like peptide	0.186
Tbx4	T-box 4	0.184
Zfp503	zinc finger protein 503	0.179
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.171
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.169
Eya1	eyes absent 1 homolog (Drosophila)	0.164
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.164
Prrx2	paired related homeobox 2	0.162
Zeb1	zinc finger E-box binding homeobox 1	0.162
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.158
Lrp2	low density lipoprotein receptor-related protein 2	0.154
Vangl2	vang-like 2 (van gogh, Drosophila)	0.152
Alx1	ALX homeobox 1	0.151
Gdf3	growth differentiation factor 3	0.144
Isl1	ISL1 transcription factor, LIM/homeodomain	0.143
Pax2	paired box gene 2	0.138
Gdf5	growth differentiation factor 5	0.136	Mouse
Dnahc5	dynein, axonemal, heavy chain 5	0.132
Dnahc11	dynein, axonemal, heavy chain 11	0.132
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.123
Hoxa13	homeobox A13	0.121
Npr3	natriuretic peptide receptor 3	0.119
Tcf21	transcription factor 21	0.117
Fgfr1	fibroblast growth factor receptor 1	0.113
En1	engrailed 1	0.113
Cldn6	claudin 6	0.113
Lrp6	low density lipoprotein receptor-related protein 6	0.113
Gas1	growth arrest specific 1	0.105
Bmp2	bone morphogenetic protein 2	0.096
Bmper	BMP-binding endothelial regulator	0.089
Twist2	twist homolog 2 (Drosophila)	0.086
Dlx5	distal-less homeobox 5	0.085
Itga8	integrin alpha 8	0.084
Bmp5	bone morphogenetic protein 5	0.079	Mouse
Mks1	Meckel syndrome, type 1	0.079
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.073
Rarb	retinoic acid receptor, beta	0.071
Smad6	MAD homolog 6 (Drosophila)	0.070
Alx3	aristaless-like homeobox 3	0.068
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.065
Megf8	multiple EGF-like-domains 8	0.063
Fgf10	fibroblast growth factor 10	0.063
Fgf9	fibroblast growth factor 9	0.061
Wnt3a	wingless-related MMTV integration site 3A	0.060
Itga3	integrin alpha 3	0.058
Gpc3	glypican 3	0.058
Foxf1a	forkhead box F1a	0.058
Gata6	GATA binding protein 6	0.057
Ctnnb1	catenin (cadherin associated protein), beta 1	0.057
Hoxb6	homeobox B6	0.056
Ptch1	patched homolog 1	0.052
Cfc1	cripto, FRL-1, cryptic family 1	0.052
Phlda2	pleckstrin homology-like domain, family A, member 2	0.049
Jag1	jagged 1	0.047
Rarg	retinoic acid receptor, gamma	0.046
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.046
Invs	inversin	0.046
Hesx1	homeobox gene expressed in ES cells	0.046
Hoxa2	homeobox A2	0.045
Mipol1	mirror-image polydactyly gene 1 homolog (human)	0.045
Hoxd9	homeobox D9	0.045
Pbx1	pre B-cell leukemia transcription factor 1	0.043
Padi3	peptidyl arginine deiminase, type III	0.042
Tmprss2	transmembrane protease, serine 2	0.042
Myod1	myogenic differentiation 1	0.041
Foxf2	forkhead box F2	0.041
Sox3	SRY-box containing gene 3	0.041
Hoxa10	homeobox A10	0.041
Cldn4	claudin 4	0.040
Gli1	GLI-Kruppel family member GLI1	0.040
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.037
Tbx2	T-box 2	0.037
Dyx1c1	dyslexia susceptibility 1 candidate 1 homolog (human)	0.037
T	brachyury	0.036
Sct	secretin	0.035
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.034
Mn1	meningioma 1	0.034
Efna4	ephrin A4	0.033
Sall4	sal-like 4 (Drosophila)	0.032
Foxa2	forkhead box A2	0.032
Cdx1	caudal type homeobox 1	0.032
Rab25	RAB25, member RAS oncogene family	0.032
Wnt6	wingless-related MMTV integration site 6	0.032
Il1f5	interleukin 1 family, member 5 (delta)	0.031
Tecta	tectorin alpha	0.031
Clcnka	chloride channel Ka	0.031
Sox7	SRY-box containing gene 7	0.031
Hoxa11	homeobox A11	0.030
Pnliprp2	pancreatic lipase-related protein 2	0.030
Ybx2	Y box protein 2	0.030
Edn3	endothelin 3	0.030
Wnt11	wingless-related MMTV integration site 11	0.030
Wnt3	wingless-related MMTV integration site 3	0.029
Osta	organic solute transporter alpha	0.029
Slc7a9	solute carrier family 7 (cationic amino acid transporter, y+ system), member 9	0.029
Gm13290	predicted gene 13290	0.029
Foxd2	forkhead box D2	0.028
Cilp2	cartilage intermediate layer protein 2	0.028
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.028
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.028
Hoxb3	homeobox B3	0.028
Pax9	paired box gene 9	0.027
Ihh	Indian hedgehog	0.027	Mouse
Barx1	BarH-like homeobox 1	0.027
Egfr	epidermal growth factor receptor	0.026
Capn9	calpain 9	0.026
Otx1	orthodenticle homolog 1 (Drosophila)	0.026
Tcfap2c	transcription factor AP-2, gamma	0.026
Folr1	folate receptor 1 (adult)	0.025
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.025
Foxd3	forkhead box D3	0.025
Gdf9	growth differentiation factor 9	0.025
Cldn7	claudin 7	0.025
Padi1	peptidyl arginine deiminase, type I	0.024
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.024
Col4a3	collagen, type IV, alpha 3	0.024
Fgf15	fibroblast growth factor 15	0.024
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.024
Upk3b	uroplakin 3B	0.023
Stc2	stanniocalcin 2	0.023
Hoxa9	homeobox A9	0.023
Cldn3	claudin 3	0.023
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.022
Nkx3-2	NK3 homeobox 2	0.022
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.022
Fmn1	formin 1	0.022
Amhr2	anti-Mullerian hormone type 2 receptor	0.021
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.021
Prop1	paired like homeodomain factor 1	0.021
Gjb3	gap junction protein, beta 3	0.021
Hoxa4	homeobox A4	0.020
Kcnk7	potassium channel, subfamily K, member 7	0.020
Slc5a11	solute carrier family 5 (sodium/glucose cotransporter), member 11	0.020
Tm4sf5	transmembrane 4 superfamily member 5	0.020
Smad3	MAD homolog 3 (Drosophila)	0.020
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.020
Dmrt1	doublesex and mab-3 related transcription factor 1	0.020
Ccdc39	coiled-coil domain containing 39	0.020
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.020
Dusp9	dual specificity phosphatase 9	0.020
Pla2g10	phospholipase A2, group X	0.020
Bnc1	basonuclin 1	0.020
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.019
Mybph	myosin binding protein H	0.019
En2	engrailed 2	0.019
Lefty2	left-right determination factor 2	0.019
Guca2b	guanylate cyclase activator 2b (retina)	0.019
Bdkrb2	bradykinin receptor, beta 2	0.019
Wt1	Wilms tumor 1 homolog	0.019
Des	desmin	0.019
Edn2	endothelin 2	0.019
Figla	folliculogenesis specific basic helix-loop-helix	0.019
Drd4	dopamine receptor D4	0.019
Slc6a20b	solute carrier family 6 (neurotransmitter transporter), member 20B	0.019
Etv2	ets variant gene 2	0.019
Fuz	fuzzy homolog (Drosophila)	0.018
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.018
Sox17	SRY-box containing gene 17	0.018
Art5	ADP-ribosyltransferase 5	0.018
Pax8	paired box gene 8	0.017
She	src homology 2 domain-containing transforming protein E	0.017
Gja1	gap junction protein, alpha 1	0.017
Hoxd8	homeobox D8	0.017
Dpep1	dipeptidase 1 (renal)	0.017
Irs3	insulin receptor substrate 3	0.017
Gja3	gap junction protein, alpha 3	0.016
Tead4	TEA domain family member 4	0.016
Col4a4	collagen, type IV, alpha 4	0.016
Stra6	stimulated by retinoic acid gene 6	0.016
6030429G01Rik	RIKEN cDNA 6030429G01 gene	0.016
Npn2	neoplastic progression 2	0.016
Pcdh12	protocadherin 12	0.016
Evx1	even skipped homeotic gene 1 homolog	0.015
Hoxd11	homeobox D11	0.015
Tcf15	transcription factor 15	0.015
Hes1	hairy and enhancer of split 1 (Drosophila)	0.015
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.015
Clic3	chloride intracellular channel 3	0.015
Fgf17	fibroblast growth factor 17	0.015
Aqp2	aquaporin 2	0.015
Ppl	periplakin	0.015
Btbd17	BTB (POZ) domain containing 17	0.015
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.015
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.015
Gjb4	gap junction protein, beta 4	0.014
Agrp	agouti related protein	0.014
Fgf18	fibroblast growth factor 18	0.014
Tcl1	T-cell lymphoma breakpoint 1	0.014
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.014
Npr2	natriuretic peptide receptor 2	0.014
Krt19	keratin 19	0.014
Fam83h	family with sequence similarity 83, member H	0.014
Lsmd1	LSM domain containing 1	0.014
Stra8	stimulated by retinoic acid gene 8	0.014
Wnt5b	wingless-related MMTV integration site 5B	0.014
Ptk7	PTK7 protein tyrosine kinase 7	0.014
Ggt1	gamma-glutamyltransferase 1	0.014
Lef1	lymphoid enhancer binding factor 1	0.014
Mapk12	mitogen-activated protein kinase 12	0.014
Wnt1	wingless-related MMTV integration site 1	0.014
Rem1	rad and gem related GTP binding protein 1	0.014
Bdkrb1	bradykinin receptor, beta 1	0.014
Nrtn	neurturin	0.014
Mylk	myosin, light polypeptide kinase	0.014
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.014
Dao	D-amino acid oxidase	0.014
Cryga	crystallin, gamma A	0.014
Cnga3	cyclic nucleotide gated channel alpha 3	0.014
Amh	anti-Mullerian hormone	0.013
Rhox6	reproductive homeobox 6	0.013
Slc23a3	solute carrier family 23 (nucleobase transporters), member 3	0.013
Vpreb1	pre-B lymphocyte gene 1	0.013
Gjb5	gap junction protein, beta 5	0.013
Trap1a	tumor rejection antigen P1A	0.013
Pkdcc	protein kinase domain containing, cytoplasmic	0.013
Pdlim3	PDZ and LIM domain 3	0.013
Olfr157	olfactory receptor 157	0.013
Pax1	paired box gene 1	0.013
Pkp3	plakophilin 3	0.013
Twist1	twist homolog 1 (Drosophila)	0.013
Dmc1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.013
Fxyd2	FXYD domain-containing ion transport regulator 2	0.013
Krt7	keratin 7	0.013
Upk2	uroplakin 2	0.012
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.012
Il13	interleukin 13	0.012
Uqcrh	ubiquinol-cytochrome c reductase hinge protein	0.012
Hoxd10	homeobox D10	0.012
Myog	myogenin	0.012
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.012
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.012
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.012
Ccdc85c	coiled-coil domain containing 85C	0.012
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.012
Fbp2	fructose bisphosphatase 2	0.012
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.012
Tgif2	TGFB-induced factor homeobox 2	0.012
D630037F22Rik	RIKEN cDNA D630037F22 gene	0.012
Prss8	protease, serine, 8 (prostasin)	0.012
Prss32	protease, serine, 32	0.012
Meox1	mesenchyme homeobox 1	0.012
Hoxb9	homeobox B9	0.012
Otog	otogelin	0.012
Hoxd4	homeobox D4	0.012
Krt84	keratin 84	0.012
Matn3	matrilin 3	0.012
Mafa	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)	0.012
Elf3	E74-like factor 3	0.012
Spry4	sprouty homolog 4 (Drosophila)	0.011
Gsx1	GS homeobox 1	0.011
Sycn	syncollin	0.011
Lama5	laminin, alpha 5	0.011
Cst8	cystatin 8 (cystatin-related epididymal spermatogenic)	0.011
Col10a1	collagen, type X, alpha 1	0.011
Crxos1	Crx opposite strand transcript 1	0.011
Fgf4	fibroblast growth factor 4	0.011
Otp	orthopedia homolog (Drosophila)	0.011
Crhr2	corticotropin releasing hormone receptor 2	0.011
Omp	olfactory marker protein	0.011
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.011
Eomes	eomesodermin homolog (Xenopus laevis)	0.011
Sod3	superoxide dismutase 3, extracellular	0.011
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.011
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.011
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.011
Gdf6	growth differentiation factor 6	0.011	Mouse
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.011
Mmp11	matrix metallopeptidase 11	0.011
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.011
Hes3	hairy and enhancer of split 3 (Drosophila)	0.011
Apob	apolipoprotein B	0.011
Smad2	MAD homolog 2 (Drosophila)	0.011
Amelx	amelogenin X chromosome	0.011
Cidec	cell death-inducing DFFA-like effector c	0.011
Fut2	fucosyltransferase 2	0.011
Krt72-ps	keratin 72, pseudogene	0.011
Cdh3	cadherin 3	0.011
Hmx1	H6 homeobox 1	0.011
Bik	BCL2-interacting killer	0.010
Kcnj15	potassium inwardly-rectifying channel, subfamily J, member 15	0.010
Plac1	placental specific protein 1	0.010
Ano1	anoctamin 1, calcium activated chloride channel	0.010
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.010
Spdef	SAM pointed domain containing ets transcription factor	0.010
Moxd2	monooxygenase, DBH-like 2	0.010
Trp63	transformation related protein 63	0.010
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.010
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.010
Mep1b	meprin 1 beta	0.010
Efnb2	ephrin B2	0.010
Hoxa5	homeobox A5	0.010
Cnn1	calponin 1	0.010
Pth1r	parathyroid hormone 1 receptor	0.010
Srcrb4d	scavenger receptor cysteine rich domain containing, group B (4 domains)	0.010