IMP

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Mus musculus

2 genes annotated in mouse

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regulation of hepatocyte differentiation

GO:0070366

Any process that modulates the frequency, rate or extent of hepatocyte differentiation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of hepatocyte differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of hepatocyte differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Tgfb2	transforming growth factor, beta 2	0.977
Fgfr2	fibroblast growth factor receptor 2	0.969
Gli3	GLI-Kruppel family member GLI3	0.921
Gopc	golgi associated PDZ and coiled-coil motif containing	0.658
Shh	sonic hedgehog	0.563
Pitx2	paired-like homeodomain transcription factor 2	0.517
Vegfa	vascular endothelial growth factor A	0.429
Ece1	endothelin converting enzyme 1	0.399
Foxc1	forkhead box C1	0.397
Hoxa1	homeobox A1	0.315
Rarg	retinoic acid receptor, gamma	0.283
Foxc2	forkhead box C2	0.252
Wnt5a	wingless-related MMTV integration site 5A	0.237
Smo	smoothened homolog (Drosophila)	0.219
Gpc3	glypican 3	0.217
Fgf8	fibroblast growth factor 8	0.215
Vangl2	vang-like 2 (van gogh, Drosophila)	0.158
Fzd8	frizzled homolog 8 (Drosophila)	0.140	Mouse
Smad6	MAD homolog 6 (Drosophila)	0.128
Pax3	paired box gene 3	0.111
Gata6	GATA binding protein 6	0.109
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.107
Acvr1	activin A receptor, type 1	0.107
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.102
Sox9	SRY-box containing gene 9	0.099
Meox2	mesenchyme homeobox 2	0.099
Fgfr1	fibroblast growth factor receptor 1	0.099
Gata4	GATA binding protein 4	0.095
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.092
Rxra	retinoid X receptor alpha	0.091
Eya1	eyes absent 1 homolog (Drosophila)	0.085
Fbln1	fibulin 1	0.082
Tbx1	T-box 1	0.079
Rarb	retinoic acid receptor, beta	0.078
Gas1	growth arrest specific 1	0.069
Rara	retinoic acid receptor, alpha	0.068
Tcfap2a	transcription factor AP-2, alpha	0.067
Mecom	MDS1 and EVI1 complex locus	0.064
Fgf10	fibroblast growth factor 10	0.057
Fzd2	frizzled homolog 2 (Drosophila)	0.055	Mouse
Bmp7	bone morphogenetic protein 7	0.052
Fzd7	frizzled homolog 7 (Drosophila)	0.052	Mouse
Fzd1	frizzled homolog 1 (Drosophila)	0.050	Mouse
Sox4	SRY-box containing gene 4	0.050
Grb10	growth factor receptor bound protein 10	0.049
Hoxa3	homeobox A3	0.047
Wnt3a	wingless-related MMTV integration site 3A	0.046
Hes1	hairy and enhancer of split 1 (Drosophila)	0.045
Hoxb3	homeobox B3	0.044
Otx2	orthodenticle homolog 2 (Drosophila)	0.043
Hoxd9	homeobox D9	0.043
Chrd	chordin	0.043
Gli2	GLI-Kruppel family member GLI2	0.043
Nodal	nodal	0.041
Tbx3	T-box 3	0.040
Isl1	ISL1 transcription factor, LIM/homeodomain	0.040
Sfrp2	secreted frizzled-related protein 2	0.039
Mrc2	mannose receptor, C type 2	0.039
Egfr	epidermal growth factor receptor	0.039
Msx2	homeobox, msh-like 2	0.037
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.037
Emp2	epithelial membrane protein 2	0.037
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.036
Zfp185	zinc finger protein 185	0.035
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.035
Lrp2	low density lipoprotein receptor-related protein 2	0.035
Sfrp1	secreted frizzled-related protein 1	0.034
Ctnnb1	catenin (cadherin associated protein), beta 1	0.034
Tead2	TEA domain family member 2	0.034
Hoxb6	homeobox B6	0.034
Tbx2	T-box 2	0.034
Bmp5	bone morphogenetic protein 5	0.033
Dll3	delta-like 3 (Drosophila)	0.033
Twist2	twist homolog 2 (Drosophila)	0.032
Itga8	integrin alpha 8	0.031
Tgfbr3	transforming growth factor, beta receptor III	0.031
Matn4	matrilin 4	0.031
Ednra	endothelin receptor type A	0.030
Nog	noggin	0.029
Fgfr3	fibroblast growth factor receptor 3	0.029
Npr3	natriuretic peptide receptor 3	0.029
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.029
Smad3	MAD homolog 3 (Drosophila)	0.028
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.027
Col4a5	collagen, type IV, alpha 5	0.027
Capn6	calpain 6	0.027
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.026
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.026
Tcf21	transcription factor 21	0.026
Ptk7	PTK7 protein tyrosine kinase 7	0.025
Pbx1	pre B-cell leukemia transcription factor 1	0.025
Zic3	zinc finger protein of the cerebellum 3	0.025
Hoxa2	homeobox A2	0.025
Efna4	ephrin A4	0.025
Gsc	goosecoid homeobox	0.024
Lhx1	LIM homeobox protein 1	0.024
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.023
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.022
Efnb1	ephrin B1	0.022
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.022
Dlg4	discs, large homolog 4 (Drosophila)	0.022
Fzd4	frizzled homolog 4 (Drosophila)	0.021	Mouse
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.021
Hand2	heart and neural crest derivatives expressed transcript 2	0.021
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.021
Efna2	ephrin A2	0.021
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.021
Foxf1a	forkhead box F1a	0.021
Hoxa9	homeobox A9	0.020
Ptprk	protein tyrosine phosphatase, receptor type, K	0.020
Dlx5	distal-less homeobox 5	0.019
Dlg2	discs, large homolog 2 (Drosophila)	0.019
Tspan12	tetraspanin 12	0.019
Jag1	jagged 1	0.019
Eda	ectodysplasin-A	0.019
Psen1	presenilin 1	0.019
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.019
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.019
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.018
Yap1	yes-associated protein 1	0.018
Cldn6	claudin 6	0.018
Rcn3	reticulocalbin 3, EF-hand calcium binding domain	0.018
Neo1	neogenin	0.018
Cldn8	claudin 8	0.018
Rhod	ras homolog gene family, member D	0.018
Cachd1	cache domain containing 1	0.018
Ptch2	patched homolog 2	0.017
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.017
Gdf10	growth differentiation factor 10	0.017
Hoxd8	homeobox D8	0.017
Sox2	SRY-box containing gene 2	0.017
Zfp503	zinc finger protein 503	0.016
Hoxa5	homeobox A5	0.016
Ctf1	cardiotrophin 1	0.016
Ddr2	discoidin domain receptor family, member 2	0.016
Ntn1	netrin 1	0.016
Hoxd3	homeobox D3	0.016
Prrx2	paired related homeobox 2	0.016
Irs1	insulin receptor substrate 1	0.016
Mmp11	matrix metallopeptidase 11	0.016
Zfhx4	zinc finger homeodomain 4	0.015
Gdnf	glial cell line derived neurotrophic factor	0.015
Pmel	premelanosome protein	0.015
Mia1	melanoma inhibitory activity 1	0.015
Sstr4	somatostatin receptor 4	0.015
Bmp6	bone morphogenetic protein 6	0.015
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.015
Cmtm8	CKLF-like MARVEL transmembrane domain containing 8	0.015
Hoxb5	homeobox B5	0.015
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.014
Fgfr4	fibroblast growth factor receptor 4	0.014
Fzd6	frizzled homolog 6 (Drosophila)	0.014	Mouse
Ephb3	Eph receptor B3	0.014
Plxna1	plexin A1	0.014
Thbs3	thrombospondin 3	0.014
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.014
Tgfa	transforming growth factor alpha	0.014
Ctnnal1	catenin (cadherin associated protein), alpha-like 1	0.014
Btbd3	BTB (POZ) domain containing 3	0.014
Ddah2	dimethylarginine dimethylaminohydrolase 2	0.014
Hoxa11	homeobox A11	0.014
Kdr	kinase insert domain protein receptor	0.014
Myl9	myosin, light polypeptide 9, regulatory	0.014
Tssk1	testis-specific serine kinase 1	0.013
Wfdc2	WAP four-disulfide core domain 2	0.013
Upk3b	uroplakin 3B	0.013
Igfbp2	insulin-like growth factor binding protein 2	0.013
Hoxd4	homeobox D4	0.013
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.013
Pax1	paired box gene 1	0.013
Pax2	paired box gene 2	0.013
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.013
Ift88	intraflagellar transport 88 homolog (Chlamydomonas)	0.013
Angpt1	angiopoietin 1	0.013
Foxg1	forkhead box G1	0.013
Meis2	Meis homeobox 2	0.013
Aplnr	apelin receptor	0.013
Twist1	twist homolog 1 (Drosophila)	0.013
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.013
Per3	period homolog 3 (Drosophila)	0.013
Tex19.1	testis expressed gene 19.1	0.013
Ptgfr	prostaglandin F receptor	0.013
Efs	embryonal Fyn-associated substrate	0.012
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.012
Gli1	GLI-Kruppel family member GLI1	0.012
Lama1	laminin, alpha 1	0.012
Sult5a1	sulfotransferase family 5A, member 1	0.012
Foxa2	forkhead box A2	0.012
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.012
Ppara	peroxisome proliferator activated receptor alpha	0.012
Tcf15	transcription factor 15	0.012
Evx2	even skipped homeotic gene 2 homolog	0.012
Col2a1	collagen, type II, alpha 1	0.012
Hoxd10	homeobox D10	0.012
Prkd1	protein kinase D1	0.012
Arhgap29	Rho GTPase activating protein 29	0.012
Foxj1	forkhead box J1	0.012
Gjc1	gap junction protein, gamma 1	0.012
Ptch1	patched homolog 1	0.011
Dnahc5	dynein, axonemal, heavy chain 5	0.011
S1pr3	sphingosine-1-phosphate receptor 3	0.011
Cfc1	cripto, FRL-1, cryptic family 1	0.011
Sh3d19	SH3 domain protein D19	0.011
Nrtn	neurturin	0.011
Ephb2	Eph receptor B2	0.011
Osr1	odd-skipped related 1 (Drosophila)	0.011
Dll1	delta-like 1 (Drosophila)	0.011
Bmper	BMP-binding endothelial regulator	0.011
Cdh6	cadherin 6	0.011
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.011
Pyy	peptide YY	0.011
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.011
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.011
Axin2	axin2	0.011
Bcam	basal cell adhesion molecule	0.011
Lrp6	low density lipoprotein receptor-related protein 6	0.011
Pcdh12	protocadherin 12	0.011
Ihh	Indian hedgehog	0.011
S1pr2	sphingosine-1-phosphate receptor 2	0.011
Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	0.011
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.011
Pax6	paired box gene 6	0.011
Wnt5b	wingless-related MMTV integration site 5B	0.011
Ptrf	polymerase I and transcript release factor	0.011
Smoc2	SPARC related modular calcium binding 2	0.011
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.010
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.010
Ptgfrn	prostaglandin F2 receptor negative regulator	0.010
Hmx1	H6 homeobox 1	0.010
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.010
Sox13	SRY-box containing gene 13	0.010
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.010
Col12a1	collagen, type XII, alpha 1	0.010
Nrcam	neuron-glia-CAM-related cell adhesion molecule	0.010
Acvr2b	activin receptor IIB	0.010
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.010
Tgfbr2	transforming growth factor, beta receptor II	0.010
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.010
Cldn3	claudin 3	0.010
Amotl2	angiomotin-like 2	0.010