IMP

Process View

Mus musculus

13 genes annotated in mouse

ganglion development

The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ganglion development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ganglion development" (in gray)

Name	Description	Probability	Func Analog Organism
Eya1	eyes absent 1 homolog (Drosophila)	0.934
Ednra	endothelin receptor type A	0.916
Prrx1	paired related homeobox 1	0.732	Mouse
Dlg4	discs, large homolog 4 (Drosophila)	0.559
Gopc	golgi associated PDZ and coiled-coil motif containing	0.552
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.522
Ret	ret proto-oncogene	0.389
Otx2	orthodenticle homolog 2 (Drosophila)	0.357
Msx2	homeobox, msh-like 2	0.347
Msx1	homeobox, msh-like 1	0.315
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.302
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.296
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.256
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.251
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.209
Acvr1	activin A receptor, type 1	0.189
Wnt5a	wingless-related MMTV integration site 5A	0.188
Isl1	ISL1 transcription factor, LIM/homeodomain	0.164
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.155
Hand2	heart and neural crest derivatives expressed transcript 2	0.152
Pbx1	pre B-cell leukemia transcription factor 1	0.140
Ednrb	endothelin receptor type B	0.138
Ece1	endothelin converting enzyme 1	0.130
Neurod1	neurogenic differentiation 1	0.129
Gli3	GLI-Kruppel family member GLI3	0.126
Fgfr2	fibroblast growth factor receptor 2	0.119
Plxna1	plexin A1	0.118
Sox9	SRY-box containing gene 9	0.116
Mid2	midline 2	0.114
Fzd1	frizzled homolog 1 (Drosophila)	0.110	Mouse
Grb10	growth factor receptor bound protein 10	0.106
Fzd8	frizzled homolog 8 (Drosophila)	0.105	Mouse
Pax3	paired box gene 3	0.103
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.102
Smad3	MAD homolog 3 (Drosophila)	0.095
Fgfr1	fibroblast growth factor receptor 1	0.095
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.094
Trim25	tripartite motif-containing 25	0.093
Phox2b	paired-like homeobox 2b	0.092
Nrtn	neurturin	0.091
Dlx5	distal-less homeobox 5	0.091
Foxc1	forkhead box C1	0.084
Unc93b1	unc-93 homolog B1 (C. elegans)	0.084
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.083
Bmp7	bone morphogenetic protein 7	0.083
Nrcam	neuron-glia-CAM-related cell adhesion molecule	0.081
Ebf3	early B-cell factor 3	0.080
Mrc2	mannose receptor, C type 2	0.080
Gdnf	glial cell line derived neurotrophic factor	0.076
Tcfap2a	transcription factor AP-2, alpha	0.075
Col9a1	collagen, type IX, alpha 1	0.074
Hes1	hairy and enhancer of split 1 (Drosophila)	0.073
Mgat3	mannoside acetylglucosaminyltransferase 3	0.070
Gsk3b	glycogen synthase kinase 3 beta	0.068
Neurog2	neurogenin 2	0.068
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.066
Cxadr	coxsackie virus and adenovirus receptor	0.065
Zfhx4	zinc finger homeodomain 4	0.065
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.065
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.061
Myf5	myogenic factor 5	0.057
Chrd	chordin	0.053
Bcar1	breast cancer anti-estrogen resistance 1	0.053
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.052
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.052
Neurod4	neurogenic differentiation 4	0.052
Msi1	Musashi homolog 1(Drosophila)	0.050
Fzd2	frizzled homolog 2 (Drosophila)	0.050	Mouse
Pax6	paired box gene 6	0.049
Efna2	ephrin A2	0.049
Gpc3	glypican 3	0.049
Fgf10	fibroblast growth factor 10	0.048
Hand1	heart and neural crest derivatives expressed transcript 1	0.047
Hoxa2	homeobox A2	0.045
Apc	adenomatosis polyposis coli	0.044
Fzd7	frizzled homolog 7 (Drosophila)	0.044	Mouse
Neurog1	neurogenin 1	0.043
Pcdh18	protocadherin 18	0.043
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.042	Mouse
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.041
Tpbg	trophoblast glycoprotein	0.040
Shh	sonic hedgehog	0.040
Zfp185	zinc finger protein 185	0.039
Tcfap2c	transcription factor AP-2, gamma	0.038
Gsc	goosecoid homeobox	0.038
Fbln1	fibulin 1	0.036
Col4a5	collagen, type IV, alpha 5	0.036
Flt1	FMS-like tyrosine kinase 1	0.035
Nes	nestin	0.034
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.033	Mouse
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.032
Smad6	MAD homolog 6 (Drosophila)	0.032
Dlg2	discs, large homolog 2 (Drosophila)	0.032
Foxd1	forkhead box D1	0.032
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.031
Aplnr	apelin receptor	0.030
Epha4	Eph receptor A4	0.030
Emp2	epithelial membrane protein 2	0.030
Hes2	hairy and enhancer of split 2 (Drosophila)	0.030
Ddr2	discoidin domain receptor family, member 2	0.029
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.029
Pcgf2	polycomb group ring finger 2	0.029
Ptprg	protein tyrosine phosphatase, receptor type, G	0.029
Gpr27	G protein-coupled receptor 27	0.029
Mtap1b	microtubule-associated protein 1B	0.029
Dach1	dachshund 1 (Drosophila)	0.029
Col12a1	collagen, type XII, alpha 1	0.029
Ntf3	neurotrophin 3	0.028
Hoxb1	homeobox B1	0.028
Cdh3	cadherin 3	0.028
Btbd3	BTB (POZ) domain containing 3	0.027
Tulp1	tubby like protein 1	0.027	Mouse
Cldn6	claudin 6	0.027
Nrg1	neuregulin 1	0.027
Ctf1	cardiotrophin 1	0.026
Sox2	SRY-box containing gene 2	0.026
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.026	Mouse
Notch3	Notch gene homolog 3 (Drosophila)	0.026
Ephb3	Eph receptor B3	0.026
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.025
Eya4	eyes absent 4 homolog (Drosophila)	0.025
Smad4	MAD homolog 4 (Drosophila)	0.024
Efs	embryonal Fyn-associated substrate	0.024
Ptpru	protein tyrosine phosphatase, receptor type, U	0.024
Nf1	neurofibromatosis 1	0.024
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.024
Ptk2	PTK2 protein tyrosine kinase 2	0.024
Prox1	prospero-related homeobox 1	0.024
Fign	fidgetin	0.024
Pou3f3	POU domain, class 3, transcription factor 3	0.023
Ephb4	Eph receptor B4	0.023
Nrp2	neuropilin 2	0.023
Fjx1	four jointed box 1 (Drosophila)	0.023
Tcf15	transcription factor 15	0.023
Foxd3	forkhead box D3	0.023
Gli2	GLI-Kruppel family member GLI2	0.023
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.022
Tgfb2	transforming growth factor, beta 2	0.021
Gas1	growth arrest specific 1	0.021
Gpr44	G protein-coupled receptor 44	0.021
Sox3	SRY-box containing gene 3	0.021
Lama5	laminin, alpha 5	0.021
Nynrin	NYN domain and retroviral integrase containing	0.021
Tbx3	T-box 3	0.021
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.020
Epha3	Eph receptor A3	0.020
Tspan12	tetraspanin 12	0.020
Rax	retina and anterior neural fold homeobox	0.020
Hoxd1	homeobox D1	0.020
Nkx6-1	NK6 homeobox 1	0.020
Tbx15	T-box 15	0.019
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.019
Galr2	galanin receptor 2	0.019
Myo10	myosin X	0.019
Cachd1	cache domain containing 1	0.019
Sh3rf1	SH3 domain containing ring finger 1	0.019
Zfp358	zinc finger protein 358	0.019
Tlx3	T-cell leukemia, homeobox 3	0.018
Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	0.018
Lpar4	lysophosphatidic acid receptor 4	0.018
Mdfi	MyoD family inhibitor	0.018
Tnks1bp1	tankyrase 1 binding protein 1	0.018
Slco5a1	solute carrier organic anion transporter family, member 5A1	0.018
Tgfbr3	transforming growth factor, beta receptor III	0.018
Ctnnal1	catenin (cadherin associated protein), alpha-like 1	0.017
Sfrp1	secreted frizzled-related protein 1	0.017
Elf3	E74-like factor 3	0.017
Ephb2	Eph receptor B2	0.017
Pde6g	phosphodiesterase 6G, cGMP-specific, rod, gamma	0.017
Fzd9	frizzled homolog 9 (Drosophila)	0.017	Mouse
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.017
Bmp2	bone morphogenetic protein 2	0.017
Nkain1	Na+/K+ transporting ATPase interacting 1	0.017
Hoxd9	homeobox D9	0.016
Matn4	matrilin 4	0.016
Smtn	smoothelin	0.016
Neo1	neogenin	0.016
Esrrb	estrogen related receptor, beta	0.016
Plxnd1	plexin D1	0.016
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.016
Capn6	calpain 6	0.016
Cdh13	cadherin 13	0.016
En1	engrailed 1	0.016
Vegfa	vascular endothelial growth factor A	0.016
Gbx2	gastrulation brain homeobox 2	0.016
Dtna	dystrobrevin alpha	0.016
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.016
Epas1	endothelial PAS domain protein 1	0.016
Zfhx3	zinc finger homeobox 3	0.016
Pdgfb	platelet derived growth factor, B polypeptide	0.016
Fgf8	fibroblast growth factor 8	0.016
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.015
Col8a1	collagen, type VIII, alpha 1	0.015
Peg10	paternally expressed 10	0.015
Dlx3	distal-less homeobox 3	0.015
Mmp16	matrix metallopeptidase 16	0.015
Fgf15	fibroblast growth factor 15	0.015
Crx	cone-rod homeobox containing gene	0.015
Smo	smoothened homolog (Drosophila)	0.015
Hoxd3	homeobox D3	0.015
Efna5	ephrin A5	0.015
Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.015
Tbx1	T-box 1	0.015
Ntf5	neurotrophin 5	0.015
Cdh4	cadherin 4	0.015
Sox1	SRY-box containing gene 1	0.015
Mmp15	matrix metallopeptidase 15	0.015
Ptk7	PTK7 protein tyrosine kinase 7	0.015
Aif1l	allograft inflammatory factor 1-like	0.015
Fgf18	fibroblast growth factor 18	0.014
Bcl6b	B-cell CLL/lymphoma 6, member B	0.014
Prrx2	paired related homeobox 2	0.014	Mouse
Fgfr4	fibroblast growth factor receptor 4	0.014
Myod1	myogenic differentiation 1	0.014
Parp12	poly (ADP-ribose) polymerase family, member 12	0.014
Twist1	twist homolog 1 (Drosophila)	0.014
Fzd6	frizzled homolog 6 (Drosophila)	0.014	Mouse
Utf1	undifferentiated embryonic cell transcription factor 1	0.014
Rtp4	receptor transporter protein 4	0.014
Utrn	utrophin	0.014
Pcdhb2	protocadherin beta 2	0.014
Samd9l	sterile alpha motif domain containing 9-like	0.014
Sox13	SRY-box containing gene 13	0.014
Rhox6	reproductive homeobox 6	0.014
Tead1	TEA domain family member 1	0.014
Axin2	axin2	0.014
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.014
Npnt	nephronectin	0.014
Vhl	von Hippel-Lindau tumor suppressor	0.013
Sox10	SRY-box containing gene 10	0.013
Fam109a	family with sequence similarity 109, member A	0.013
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.013
Plxna2	plexin A2	0.013
Angpt1	angiopoietin 1	0.013
Mfap2	microfibrillar-associated protein 2	0.013
Sorbs3	sorbin and SH3 domain containing 3	0.013
Sox11	SRY-box containing gene 11	0.013
Stra6	stimulated by retinoic acid gene 6	0.013
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.013
Zbp1	Z-DNA binding protein 1	0.013
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.013
Tbx2	T-box 2	0.013
Prx	periaxin	0.013
Kitl	kit ligand	0.013
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.013
Myog	myogenin	0.013
Ids	iduronate 2-sulfatase	0.012
Creb3l1	cAMP responsive element binding protein 3-like 1	0.012
Hoxd4	homeobox D4	0.012
Smad5	MAD homolog 5 (Drosophila)	0.012
Plekha7	pleckstrin homology domain containing, family A member 7	0.012
Gria4	glutamate receptor, ionotropic, AMPA4 (alpha 4)	0.012
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.012	Mouse
Bmp5	bone morphogenetic protein 5	0.012
Hapln1	hyaluronan and proteoglycan link protein 1	0.012
Nefm	neurofilament, medium polypeptide	0.012
Gab2	growth factor receptor bound protein 2-associated protein 2	0.012
Klf12	Kruppel-like factor 12	0.012
Per3	period homolog 3 (Drosophila)	0.012
Onecut1	one cut domain, family member 1	0.012
Etv2	ets variant gene 2	0.012
Ebf2	early B-cell factor 2	0.012
Sirpa	signal-regulatory protein alpha	0.012
Pxn	paxillin	0.012
Sema4b	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	0.012
Folr1	folate receptor 1 (adult)	0.011
Cib2	calcium and integrin binding family member 2	0.011
Hoxb6	homeobox B6	0.011
Tcfeb	transcription factor EB	0.011
Alpl	alkaline phosphatase, liver/bone/kidney	0.011
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.011
Cdk14	cyclin-dependent kinase 14	0.011
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.011
Bmp4	bone morphogenetic protein 4	0.011
Ehd2	EH-domain containing 2	0.011
Plxna4	plexin A4	0.011
Rarg	retinoic acid receptor, gamma	0.011
Hmx2	H6 homeobox 2	0.011
D14Ertd668e	DNA segment, Chr 14, ERATO Doi 668, expressed	0.011
Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	0.011
Nsd1	nuclear receptor-binding SET-domain protein 1	0.011
Phox2a	paired-like homeobox 2a	0.011	Mouse
Ltbp4	latent transforming growth factor beta binding protein 4	0.011
Lpar1	lysophosphatidic acid receptor 1	0.011
Wnt1	wingless-related MMTV integration site 1	0.011
Arhgef40	Rho guanine nucleotide exchange factor (GEF) 40	0.011
Nfib	nuclear factor I/B	0.011
Gjc1	gap junction protein, gamma 1	0.011
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.011	Mouse
Rnf135	ring finger protein 135	0.011
Sstr4	somatostatin receptor 4	0.011
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.011
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.011
Arhgef25	Rho guanine nucleotide exchange factor (GEF) 25	0.011
Srgap1	SLIT-ROBO Rho GTPase activating protein 1	0.011
Kcnj2	potassium inwardly-rectifying channel, subfamily J, member 2	0.011
Amhr2	anti-Mullerian hormone type 2 receptor	0.011
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.010
Shroom1	shroom family member 1	0.010
Ptrf	polymerase I and transcript release factor	0.010
Neurog3	neurogenin 3	0.010
Mtap2	microtubule-associated protein 2	0.010
Sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.010	Mouse
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.010
Cpd	carboxypeptidase D	0.010
Pcdh1	protocadherin 1	0.010
Ccm2	cerebral cavernous malformation 2 homolog (human)	0.010
Sox5	SRY-box containing gene 5	0.010
Dll3	delta-like 3 (Drosophila)	0.010