IMP

Process View

Mus musculus

1 genes annotated in mouse

regulation of neutrophil mediated killing of gram negative bacterium

Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of neutrophil mediated killing of gram negative bacterium"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of neutrophil mediated killing of gram negative bacterium" (in gray)

Name	Description	Probability	Func Analog Organism
Cxcl2	chemokine (C-X-C motif) ligand 2	0.974	Mouse
Il1rn	interleukin 1 receptor antagonist	0.961
Ccl2	chemokine (C-C motif) ligand 2	0.961
Cxcl1	chemokine (C-X-C motif) ligand 1	0.920	Mouse
Ccl7	chemokine (C-C motif) ligand 7	0.916
Il6	interleukin 6	0.747
Ccl12	chemokine (C-C motif) ligand 12	0.658
Saa3	serum amyloid A 3	0.653
Il1b	interleukin 1 beta	0.645
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.640
Irg1	immunoresponsive gene 1	0.553
Cxcl10	chemokine (C-X-C motif) ligand 10	0.535	Mouse
Clec4d	C-type lectin domain family 4, member d	0.461
Iigp1	interferon inducible GTPase 1	0.385
Ch25h	cholesterol 25-hydroxylase	0.375
Ccl3	chemokine (C-C motif) ligand 3	0.357
Isg15	ISG15 ubiquitin-like modifier	0.335
Cxcl5	chemokine (C-X-C motif) ligand 5	0.326
Mmp13	matrix metallopeptidase 13	0.287
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.269
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.268
Cd14	CD14 antigen	0.216
Ccl8	chemokine (C-C motif) ligand 8	0.210
Atf3	activating transcription factor 3	0.200
Slpi	secretory leukocyte peptidase inhibitor	0.168
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.163
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.157
Clec4e	C-type lectin domain family 4, member e	0.154
Plaur	plasminogen activator, urokinase receptor	0.152
Selp	selectin, platelet	0.151
Slfn4	schlafen 4	0.150
Rsad2	radical S-adenosyl methionine domain containing 2	0.128
Il1a	interleukin 1 alpha	0.128
Serpinb2	serine (or cysteine) peptidase inhibitor, clade B, member 2	0.113
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.106
Ccr1	chemokine (C-C motif) receptor 1	0.105
Usp18	ubiquitin specific peptidase 18	0.093
Ptgs2	prostaglandin-endoperoxide synthase 2	0.092
Ereg	epiregulin	0.090
Igtp	interferon gamma induced GTPase	0.088
Niacr1	niacin receptor 1	0.083
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.081
Bcl3	B-cell leukemia/lymphoma 3	0.080
Mmp12	matrix metallopeptidase 12	0.079
Mx2	myxovirus (influenza virus) resistance 2	0.078
Fpr2	formyl peptide receptor 2	0.069
Msr1	macrophage scavenger receptor 1	0.065
Gbp2	guanylate binding protein 2	0.064
Ifi47	interferon gamma inducible protein 47	0.060
Tgtp2	T-cell specific GTPase 2	0.060
Gbp3	guanylate binding protein 3	0.055
Mmp3	matrix metallopeptidase 3	0.053
Ccl4	chemokine (C-C motif) ligand 4	0.053
Lcn2	lipocalin 2	0.050
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.045
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.044
Il1r2	interleukin 1 receptor, type II	0.043
Timp1	tissue inhibitor of metalloproteinase 1	0.041
Irf7	interferon regulatory factor 7	0.040
Adam8	a disintegrin and metallopeptidase domain 8	0.038
Areg	amphiregulin	0.037
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.035
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.035
Junb	Jun-B oncogene	0.034
Fosl1	fos-like antigen 1	0.034
Ifng	interferon gamma	0.034
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.034
Irgm2	immunity-related GTPase family M member 2	0.032
Ifi44	interferon-induced protein 44	0.030
Chi3l3	chitinase 3-like 3	0.029
Il1rl1	interleukin 1 receptor-like 1	0.028
Ccl5	chemokine (C-C motif) ligand 5	0.028
Hmox1	heme oxygenase (decycling) 1	0.027
Gdf15	growth differentiation factor 15	0.027
Cxcl3	chemokine (C-X-C motif) ligand 3	0.027
Ifih1	interferon induced with helicase C domain 1	0.025
Osmr	oncostatin M receptor	0.025
Il1r1	interleukin 1 receptor, type I	0.025
Socs3	suppressor of cytokine signaling 3	0.025
Nlrp3	NLR family, pyrin domain containing 3	0.024
Fosb	FBJ osteosarcoma oncogene B	0.023
1600029D21Rik	RIKEN cDNA 1600029D21 gene	0.023
Tfpi2	tissue factor pathway inhibitor 2	0.023
Zbp1	Z-DNA binding protein 1	0.022
Irgm1	immunity-related GTPase family M member 1	0.022
Tnf	tumor necrosis factor	0.022
Sele	selectin, endothelial cell	0.022
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.021
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.021
Arid5a	AT rich interactive domain 5A (MRF1-like)	0.021
Il18rap	interleukin 18 receptor accessory protein	0.020
Slfn1	schlafen 1	0.020
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.020
Mx1	myxovirus (influenza virus) resistance 1	0.020
Ubd	ubiquitin D	0.020
Tlr2	toll-like receptor 2	0.019
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.019
Fcgr1	Fc receptor, IgG, high affinity I	0.019
Ppbp	pro-platelet basic protein	0.019
Gbp7	guanylate binding protein 7	0.018
C3ar1	complement component 3a receptor 1	0.017
F13a1	coagulation factor XIII, A1 subunit	0.017
Cdcp1	CUB domain containing protein 1	0.017
Cd274	CD274 antigen	0.017
Egr2	early growth response 2	0.017
Ifi202b	interferon activated gene 202B	0.016
Sprr1a	small proline-rich protein 1A	0.016
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.016
Plscr1	phospholipid scramblase 1	0.016
Rgs16	regulator of G-protein signaling 16	0.015
AI607873	expressed sequence AI607873	0.015
Ccl11	chemokine (C-C motif) ligand 11	0.015
Gbp6	guanylate binding protein 6	0.015
Ier3	immediate early response 3	0.015
Fos	FBJ osteosarcoma oncogene	0.014
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.014
Ccrl2	chemokine (C-C motif) receptor-like 2	0.014
Akr1b8	aldo-keto reductase family 1, member B8	0.014
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.014
Mmp8	matrix metallopeptidase 8	0.013
Chi3l1	chitinase 3-like 1	0.013
Afp	alpha fetoprotein	0.013
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.013
Zfp36	zinc finger protein 36	0.012
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.012
C2	complement component 2 (within H-2S)	0.012
Gbp1	guanylate binding protein 1	0.012
Cfb	complement factor B	0.012
Cxcl16	chemokine (C-X-C motif) ligand 16	0.012
Rgs1	regulator of G-protein signaling 1	0.011
Cdh1	cadherin 1	0.011
F10	coagulation factor X	0.011
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.011
C5ar1	complement component 5a receptor 1	0.011
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.011
Il18bp	interleukin 18 binding protein	0.011
Has2	hyaluronan synthase 2	0.011
Upp1	uridine phosphorylase 1	0.010
H2-Q8	histocompatibility 2, Q region locus 8	0.010
Gch1	GTP cyclohydrolase 1	0.010
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.010
Procr	protein C receptor, endothelial	0.010