IMP

Process View

Mus musculus

15 genes annotated in mouse

negative regulation of transmembrane transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of transmembrane transport"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of transmembrane transport" (in gray)

Name	Description	Probability	Func Analog Organism
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.650
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.594
Neurod1	neurogenic differentiation 1	0.555	Mouse
Ldb3	LIM domain binding 3	0.399
Pax6	paired box gene 6	0.237
Otx2	orthodenticle homolog 2 (Drosophila)	0.216
Neurod4	neurogenic differentiation 4	0.208	Mouse
Kiss1	KiSS-1 metastasis-suppressor	0.135
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.127	Mouse
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.106
Shh	sonic hedgehog	0.101
Neurog3	neurogenin 3	0.091	Mouse
Lep	leptin	0.091
Neurog2	neurogenin 2	0.088	Mouse
Lhx3	LIM homeobox protein 3	0.085
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.083
Nos1	nitric oxide synthase 1, neuronal	0.080
Hand2	heart and neural crest derivatives expressed transcript 2	0.077	Mouse
Gnrh1	gonadotropin releasing hormone 1	0.077
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.076
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.063
Onecut1	one cut domain, family member 1	0.061
Isl1	ISL1 transcription factor, LIM/homeodomain	0.061
Gata1	GATA binding protein 1	0.060
Gpr50	G-protein-coupled receptor 50	0.055
Kcnk3	potassium channel, subfamily K, member 3	0.054
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.052
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.047
Emx1	empty spiracles homolog 1 (Drosophila)	0.045
Ptf1a	pancreas specific transcription factor, 1a	0.045	Mouse
Mecom	MDS1 and EVI1 complex locus	0.044
Ptgs2	prostaglandin-endoperoxide synthase 2	0.043
Gata4	GATA binding protein 4	0.042
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.041
Mybpc3	myosin binding protein C, cardiac	0.040
Ank1	ankyrin 1, erythroid	0.040
Ryr2	ryanodine receptor 2, cardiac	0.038
Nos3	nitric oxide synthase 3, endothelial cell	0.038
Hrc	histidine rich calcium binding protein	0.038
Dtna	dystrobrevin alpha	0.038
Pitx2	paired-like homeodomain transcription factor 2	0.037
En1	engrailed 1	0.034
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.034
Gjd3	gap junction protein, delta 3	0.033
Vegfa	vascular endothelial growth factor A	0.033
Actn2	actinin alpha 2	0.032	Human
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.031
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.030
Btk	Bruton agammaglobulinemia tyrosine kinase	0.030
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.030
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.029
Pnliprp2	pancreatic lipase-related protein 2	0.029
Crb1	crumbs homolog 1 (Drosophila)	0.029
Tgfbr1	transforming growth factor, beta receptor I	0.028
Pten	phosphatase and tensin homolog	0.028
Hes1	hairy and enhancer of split 1 (Drosophila)	0.028
Igh	immunoglobulin heavy chain complex	0.028
Nhlh2	nescient helix loop helix 2	0.028	Mouse
Ccm2	cerebral cavernous malformation 2 homolog (human)	0.027
Il6st	interleukin 6 signal transducer	0.026
Pax9	paired box gene 9	0.025
Cd40	CD40 antigen	0.025
Efna2	ephrin A2	0.025
Dmpk	dystrophia myotonica-protein kinase	0.025
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.025	Mouse
Tal1	T-cell acute lymphocytic leukemia 1	0.025	Mouse
Prkce	protein kinase C, epsilon	0.024
Tgfb1	transforming growth factor, beta 1	0.024
Xk	Kell blood group precursor (McLeod phenotype) homolog	0.024
Prox1	prospero-related homeobox 1	0.023
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.022
Mpl	myeloproliferative leukemia virus oncogene	0.022
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.022
Slc12a2	solute carrier family 12, member 2	0.022
Lhx5	LIM homeobox protein 5	0.022
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.022
Des	desmin	0.022
Hand1	heart and neural crest derivatives expressed transcript 1	0.022	Mouse
Ebf2	early B-cell factor 2	0.021
Myl3	myosin, light polypeptide 3	0.021
Irs2	insulin receptor substrate 2	0.021	Human
Plin4	perilipin 4	0.020
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.020
Sycn	syncollin	0.020
Zeb1	zinc finger E-box binding homeobox 1	0.020
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.020
Amhr2	anti-Mullerian hormone type 2 receptor	0.020
Lox	lysyl oxidase	0.019
Pkd1	polycystic kidney disease 1 homolog	0.019	Mouse
Add1	adducin 1 (alpha)	0.019
Nppa	natriuretic peptide type A	0.019
Myh7	myosin, heavy polypeptide 7, cardiac muscle, beta	0.019
Zfp592	zinc finger protein 592	0.019
Tcap	titin-cap	0.019
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.019
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.019
Atoh7	atonal homolog 7 (Drosophila)	0.019	Mouse
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.019
Tcf15	transcription factor 15	0.019	Mouse
Grb2	growth factor receptor bound protein 2	0.018
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.018
Insm1	insulinoma-associated 1	0.018
Pou4f2	POU domain, class 4, transcription factor 2	0.018
Abcc8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.018
Foxc1	forkhead box C1	0.018
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.017
Vdr	vitamin D receptor	0.017
Fgf18	fibroblast growth factor 18	0.017
Tgfbr2	transforming growth factor, beta receptor II	0.017
Igbp1	immunoglobulin (CD79A) binding protein 1	0.017
Clps	colipase, pancreatic	0.017
Apobec2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2	0.017
Lhx9	LIM homeobox protein 9	0.017
Lmo2	LIM domain only 2	0.017
Dmd	dystrophin, muscular dystrophy	0.016
Esrrb	estrogen related receptor, beta	0.016
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.016
Prx	periaxin	0.016
Hoxd13	homeobox D13	0.016
Smad3	MAD homolog 3 (Drosophila)	0.016
Plcg2	phospholipase C, gamma 2	0.016
Msx1	homeobox, msh-like 1	0.016
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.016
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.016
Tnnt3	troponin T3, skeletal, fast	0.016
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.016
Pik3r3	phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)	0.016
Cd44	CD44 antigen	0.016
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.016
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.016
Art5	ADP-ribosyltransferase 5	0.015
Cntn2	contactin 2	0.015
Clock	circadian locomotor output cycles kaput	0.015
Myom2	myomesin 2	0.015
Prlr	prolactin receptor	0.015
Edn3	endothelin 3	0.014
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.014
Casq2	calsequestrin 2	0.014
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.014
Pdx1	pancreatic and duodenal homeobox 1	0.014
Cox8b	cytochrome c oxidase, subunit VIIIb	0.014
Drd2	dopamine receptor D2	0.014	Human Rat
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.014
Prph	peripherin	0.014
Scn10a	sodium channel, voltage-gated, type X, alpha	0.014
Tg	thyroglobulin	0.014
Pou3f2	POU domain, class 3, transcription factor 2	0.014
Csnk1g2	casein kinase 1, gamma 2	0.014
Stim2	stromal interaction molecule 2	0.014
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.014
Bcl6	B-cell leukemia/lymphoma 6	0.014
Ckmt2	creatine kinase, mitochondrial 2	0.014
Prph2	peripherin 2	0.013
Ren1	renin 1 structural	0.013
Igfbpl1	insulin-like growth factor binding protein-like 1	0.013
Gdf11	growth differentiation factor 11	0.013
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.013
Alpk3	alpha-kinase 3	0.013
Prdx6	peroxiredoxin 6	0.013
Prkcd	protein kinase C, delta	0.013
Mapk12	mitogen-activated protein kinase 12	0.013
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.013
Wnk4	WNK lysine deficient protein kinase 4	0.013
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.013
Phox2b	paired-like homeobox 2b	0.013
Ankrd2	ankyrin repeat domain 2 (stretch responsive muscle)	0.013
Mks1	Meckel syndrome, type 1	0.013
Col22a1	collagen, type XXII, alpha 1	0.012
Pitx1	paired-like homeodomain transcription factor 1	0.012
St8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	0.012
Xiap	X-linked inhibitor of apoptosis	0.012
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.012
Tbx20	T-box 20	0.012
Prkcc	protein kinase C, gamma	0.012
Srrm4	serine/arginine repetitive matrix 4	0.012
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.012
Gata2	GATA binding protein 2	0.012
Lhx6	LIM homeobox protein 6	0.012
Tnnt2	troponin T2, cardiac	0.012
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.012
Bdkrb2	bradykinin receptor, beta 2	0.012
Foxc2	forkhead box C2	0.012
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.012
Srpk3	serine/arginine-rich protein specific kinase 3	0.011
Pygm	muscle glycogen phosphorylase	0.011
Notch2	Notch gene homolog 2 (Drosophila)	0.011
Fgf15	fibroblast growth factor 15	0.011
Rictor	RPTOR independent companion of MTOR, complex 2	0.011
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.011	Mouse
Foxh1	forkhead box H1	0.011
Myom1	myomesin 1	0.011
Hes2	hairy and enhancer of split 2 (Drosophila)	0.011
Xirp1	xin actin-binding repeat containing 1	0.011
Cbl	Casitas B-lineage lymphoma	0.011
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.011
Inpp5d	inositol polyphosphate-5-phosphatase D	0.011
Acvrl1	activin A receptor, type II-like 1	0.011
Arrb1	arrestin, beta 1	0.011
Fbn1	fibrillin 1	0.011
Cyp11b1	cytochrome P450, family 11, subfamily b, polypeptide 1	0.011
Fshr	follicle stimulating hormone receptor	0.011
Olfr70	olfactory receptor 70	0.011
Hoxb1	homeobox B1	0.011
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.011
Mark2	MAP/microtubule affinity-regulating kinase 2	0.011
Eps8	epidermal growth factor receptor pathway substrate 8	0.011
Hoxa1	homeobox A1	0.011
Tal2	T-cell acute lymphocytic leukemia 2	0.011	Mouse
Tnni3	troponin I, cardiac 3	0.011
Lyz2	lysozyme 2	0.010
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.010
Cox6a2	cytochrome c oxidase, subunit VI a, polypeptide 2	0.010
Rhag	Rhesus blood group-associated A glycoprotein	0.010
Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.010
Pgam2	phosphoglycerate mutase 2	0.010
Phkg1	phosphorylase kinase gamma 1	0.010
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.010
Smyd1	SET and MYND domain containing 1	0.010
Thra	thyroid hormone receptor alpha	0.010
Fgf6	fibroblast growth factor 6	0.010
Igfbp1	insulin-like growth factor binding protein 1	0.010
Gsc	goosecoid homeobox	0.010
Actc1	actin, alpha, cardiac muscle 1	0.010
Nrap	nebulin-related anchoring protein	0.010
Cox5a	cytochrome c oxidase, subunit Va	0.010