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Mus musculus

19 genes annotated in mouse

synaptic vesicle recycling

The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "synaptic vesicle recycling"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "synaptic vesicle recycling" (in gray)

Name	Description	Probability	Func Analog Organism
Dlg4	discs, large homolog 4 (Drosophila)	1.000
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.998
Dnm1	dynamin 1	0.997	Fly
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.953
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.906	Fly
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.903
Grb2	growth factor receptor bound protein 2	0.776
Ap2a2	adaptor protein complex AP-2, alpha 2 subunit	0.730	Fly
Shc1	src homology 2 domain-containing transforming protein C1	0.589
Stx1a	syntaxin 1A (brain)	0.570
Nrxn1	neurexin I	0.524	Fly
Dlg2	discs, large homolog 2 (Drosophila)	0.493	Mouse
Eps15	epidermal growth factor receptor pathway substrate 15	0.473	Worm
Nrxn3	neurexin III	0.468	Fly
Sh3gl2	SH3-domain GRB2-like 2	0.450
Cltc	clathrin, heavy polypeptide (Hc)	0.431
Pip5k1c	phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma	0.417
Nrcam	neuron-glia-CAM-related cell adhesion molecule	0.367
Nrxn2	neurexin II	0.363	Fly
Snap25	synaptosomal-associated protein 25	0.320
Arhgap31	Rho GTPase activating protein 31	0.309
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.291
Pacsin1	protein kinase C and casein kinase substrate in neurons 1	0.290
Dlg1	discs, large homolog 1 (Drosophila)	0.238	Mouse
Sh3kbp1	SH3-domain kinase binding protein 1	0.186
Pdcd6ip	programmed cell death 6 interacting protein	0.177
Vamp2	vesicle-associated membrane protein 2	0.142
Nsf	N-ethylmaleimide sensitive fusion protein	0.140
Arc	activity regulated cytoskeletal-associated protein	0.139
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.116
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.112
Cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.099
Adam9	a disintegrin and metallopeptidase domain 9 (meltrin gamma)	0.091
Tubb4	tubulin, beta 4	0.083
Rph3a	rabphilin 3A	0.082
Cbl	Casitas B-lineage lymphoma	0.081
Scn8a	sodium channel, voltage-gated, type VIII, alpha	0.081
Cit	citron	0.075
Tmem123	transmembrane protein 123	0.072
Syt1	synaptotagmin I	0.072	Fly
Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	0.070
Syn1	synapsin I	0.068
App	amyloid beta (A4) precursor protein	0.068
Smad4	MAD homolog 4 (Drosophila)	0.066
Ptpn18	protein tyrosine phosphatase, non-receptor type 18	0.065
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.065
Atp6v0a1	ATPase, H+ transporting, lysosomal V0 subunit A1	0.064
Dlg3	discs, large homolog 3 (Drosophila)	0.062	Mouse
Shank2	SH3/ankyrin domain gene 2	0.060
Nostrin	nitric oxide synthase trafficker	0.058
Axin1	axin 1	0.057
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.056
Mta1	metastasis associated 1	0.055
Mtap2	microtubule-associated protein 2	0.054
Bsn	bassoon	0.053
Klc2	kinesin light chain 2	0.052
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.048
Syp	synaptophysin	0.047
Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	0.046
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.045
Gsk3b	glycogen synthase kinase 3 beta	0.045
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.043
Stxbp1	syntaxin binding protein 1	0.041
Abi1	abl-interactor 1	0.040
Dnm2	dynamin 2	0.040	Fly
Egfr	epidermal growth factor receptor	0.038
Syn2	synapsin II	0.038
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.037
Gng3	guanine nucleotide binding protein (G protein), gamma 3	0.035
Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1	0.035
Gria4	glutamate receptor, ionotropic, AMPA4 (alpha 4)	0.035
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.035
Grm1	glutamate receptor, metabotropic 1	0.034
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.033
Abcb9	ATP-binding cassette, sub-family B (MDR/TAP), member 9	0.032
Kif1a	kinesin family member 1A	0.032	Fly
Pik3r2	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)	0.030
Prkcc	protein kinase C, gamma	0.030
Homer1	homer homolog 1 (Drosophila)	0.030
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.030
Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	0.029
Smad3	MAD homolog 3 (Drosophila)	0.029
Pfn2	profilin 2	0.028
Tbk1	TANK-binding kinase 1	0.028
Rab5b	RAB5B, member RAS oncogene family	0.028	Fly
Cttn	cortactin	0.027
Lrp8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	0.027
Smad1	MAD homolog 1 (Drosophila)	0.027
Plcb1	phospholipase C, beta 1	0.026
Lin7b	lin-7 homolog B (C. elegans)	0.026
Kif5c	kinesin family member 5C	0.025
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.025
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.025
Hsp90b1	heat shock protein 90, beta (Grp94), member 1	0.025
Drd2	dopamine receptor D2	0.024
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.024
Amph	amphiphysin	0.023
Ina	internexin neuronal intermediate filament protein, alpha	0.023
Nek7	NIMA (never in mitosis gene a)-related expressed kinase 7	0.023
Kif3b	kinesin family member 3B	0.023
Ap2a1	adaptor protein complex AP-2, alpha 1 subunit	0.023	Fly
Ptprn	protein tyrosine phosphatase, receptor type, N	0.023
Lrp1	low density lipoprotein receptor-related protein 1	0.023
Vapa	vesicle-associated membrane protein, associated protein A	0.023
Bace1	beta-site APP cleaving enzyme 1	0.022
Kalrn	kalirin, RhoGEF kinase	0.022
Grik5	glutamate receptor, ionotropic, kainate 5 (gamma 2)	0.022
Prkar2b	protein kinase, cAMP dependent regulatory, type II beta	0.022
Atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	0.022
Gab1	growth factor receptor bound protein 2-associated protein 1	0.022
Mef2a	myocyte enhancer factor 2A	0.022
Mapk8ip2	mitogen-activated protein kinase 8 interacting protein 2	0.021
Mark4	MAP/microtubule affinity-regulating kinase 4	0.021
Pcdh10	protocadherin 10	0.021
Scn1a	sodium channel, voltage-gated, type I, alpha	0.021
Ids	iduronate 2-sulfatase	0.021
Snap91	synaptosomal-associated protein 91	0.021
Clip2	CAP-GLY domain containing linker protein 2	0.020
Jmjd1c	jumonji domain containing 1C	0.020
Inppl1	inositol polyphosphate phosphatase-like 1	0.020
Nefm	neurofilament, medium polypeptide	0.020
Kif3a	kinesin family member 3A	0.019
Fmn2	formin 2	0.019
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.019
Rit2	Ras-like without CAAX 2	0.019
Resp18	regulated endocrine-specific protein 18	0.019
Frs2	fibroblast growth factor receptor substrate 2	0.019
Shc2	SHC (Src homology 2 domain containing) transforming protein 2	0.019
Vsnl1	visinin-like 1	0.019
Lin7c	lin-7 homolog C (C. elegans)	0.018
Gfap	glial fibrillary acidic protein	0.018
Ap2b1	adaptor-related protein complex 2, beta 1 subunit	0.018	Rat
Ptpn9	protein tyrosine phosphatase, non-receptor type 9	0.018
Hspa12a	heat shock protein 12A	0.018
Gnao1	guanine nucleotide binding protein, alpha O	0.018
Stxbp3a	syntaxin binding protein 3A	0.018	Mouse
Kif5a	kinesin family member 5A	0.018
Cntnap1	contactin associated protein-like 1	0.017
Adam15	a disintegrin and metallopeptidase domain 15 (metargidin)	0.017
Nefl	neurofilament, light polypeptide	0.017
Cast	calpastatin	0.017
Lrp2	low density lipoprotein receptor-related protein 2	0.017
Hcn2	hyperpolarization-activated, cyclic nucleotide-gated K+ 2	0.017
Hivep3	human immunodeficiency virus type I enhancer binding protein 3	0.017
Atxn2	ataxin 2	0.017
Ckmt1	creatine kinase, mitochondrial 1, ubiquitous	0.016
Rasgrp1	RAS guanyl releasing protein 1	0.016
Dsg1a	desmoglein 1 alpha	0.016
Rab1	RAB1, member RAS oncogene family	0.016
Grid2	glutamate receptor, ionotropic, delta 2	0.016
Calb2	calbindin 2	0.016
Tmem30a	transmembrane protein 30A	0.016
Cbln1	cerebellin 1 precursor protein	0.016
Ccdc64b	coiled-coil domain containing 64B	0.016
Htt	huntingtin	0.016
Abca2	ATP-binding cassette, sub-family A (ABC1), member 2	0.016
Actl6b	actin-like 6B	0.016
Tjp1	tight junction protein 1	0.016
Usp32	ubiquitin specific peptidase 32	0.016
Pfkm	phosphofructokinase, muscle	0.015
Lgi1	leucine-rich repeat LGI family, member 1	0.015
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.015
St8sia5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5	0.015
Kcnip4	Kv channel interacting protein 4	0.015
Mapt	microtubule-associated protein tau	0.015
Lamp2	lysosomal-associated membrane protein 2	0.015
Fzd1	frizzled homolog 1 (Drosophila)	0.015
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.015
Praf2	PRA1 domain family 2	0.015
Cib2	calcium and integrin binding family member 2	0.015
Cntn1	contactin 1	0.015
Inpp5d	inositol polyphosphate-5-phosphatase D	0.015
Wdr26	WD repeat domain 26	0.015
Nrip3	nuclear receptor interacting protein 3	0.015
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.014
Napb	N-ethylmaleimide sensitive fusion protein attachment protein beta	0.014
Cdh20	cadherin 20	0.014
Lima1	LIM domain and actin binding 1	0.014
Hcn1	hyperpolarization-activated, cyclic nucleotide-gated K+ 1	0.014
Sacm1l	SAC1 (suppressor of actin mutations 1, homolog)-like (S. cerevisiae)	0.014
Dab2ip	disabled homolog 2 (Drosophila) interacting protein	0.014
Eml6	echinoderm microtubule associated protein like 6	0.014
Usp12	ubiquitin specific peptidase 12	0.014
Pcsk1n	proprotein convertase subtilisin/kexin type 1 inhibitor	0.013
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.013
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.013
Kcnab1	potassium voltage-gated channel, shaker-related subfamily, beta member 1	0.013
Epb4.1l1	erythrocyte protein band 4.1-like 1	0.013
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.013
Mapk3	mitogen-activated protein kinase 3	0.013
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.013
Dnalc4	dynein, axonemal, light chain 4	0.013
Krit1	KRIT1, ankyrin repeat containing	0.013
Sos2	son of sevenless homolog 2 (Drosophila)	0.013
Sos1	son of sevenless homolog 1 (Drosophila)	0.013
Wnk2	WNK lysine deficient protein kinase 2	0.013
Mgat3	mannoside acetylglucosaminyltransferase 3	0.013
Dtna	dystrobrevin alpha	0.013
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.013
Gnaz	guanine nucleotide binding protein, alpha z subunit	0.012
Atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.012
Ppp2r2b	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform	0.012
Rusc1	RUN and SH3 domain containing 1	0.012
Fzd7	frizzled homolog 7 (Drosophila)	0.012
Sult4a1	sulfotransferase family 4A, member 1	0.012
Reep2	receptor accessory protein 2	0.012
Cpeb4	cytoplasmic polyadenylation element binding protein 4	0.012
Eno2	enolase 2, gamma neuronal	0.012
Vldlr	very low density lipoprotein receptor	0.012
Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	0.012
Nptn	neuroplastin	0.012
Numb	numb gene homolog (Drosophila)	0.012
Mapk10	mitogen-activated protein kinase 10	0.012
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.012
Rps6kb2	ribosomal protein S6 kinase, polypeptide 2	0.012
Dennd1a	DENN/MADD domain containing 1A	0.011
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.011
Mknk1	MAP kinase-interacting serine/threonine kinase 1	0.011
Cpeb2	cytoplasmic polyadenylation element binding protein 2	0.011
Acsl4	acyl-CoA synthetase long-chain family member 4	0.011
Dapk1	death associated protein kinase 1	0.011
Rnf103	ring finger protein 103	0.011
Ppp6r2	protein phosphatase 6, regulatory subunit 2	0.011
Ache	acetylcholinesterase	0.011
Stt3a	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)	0.011
Pacrg	PARK2 co-regulated	0.011
Elmo2	engulfment and cell motility 2, ced-12 homolog (C. elegans)	0.011
Arhgap30	Rho GTPase activating protein 30	0.011
Syngr1	synaptogyrin 1	0.011
Abcc8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.011
Sdcbp	syndecan binding protein	0.011
Baiap2	brain-specific angiogenesis inhibitor 1-associated protein 2	0.011
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.011
Alas2	aminolevulinic acid synthase 2, erythroid	0.011
Arhgef5	Rho guanine nucleotide exchange factor (GEF) 5	0.011
Scg3	secretogranin III	0.011
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.011
Arl1	ADP-ribosylation factor-like 1	0.011
Elk1	ELK1, member of ETS oncogene family	0.011
Magt1	magnesium transporter 1	0.010
Cntnap2	contactin associated protein-like 2	0.010
Ppfia2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	0.010
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.010
Pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	0.010
Rap1a	RAS-related protein-1a	0.010
Mtmr7	myotubularin related protein 7	0.010
Scn1b	sodium channel, voltage-gated, type I, beta	0.010
Cend1	cell cycle exit and neuronal differentiation 1	0.010
Fgf12	fibroblast growth factor 12	0.010
Ttyh1	tweety homolog 1 (Drosophila)	0.010
Slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.010
Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3	0.010
6430548M08Rik	RIKEN cDNA 6430548M08 gene	0.010