IMP

Process View

Mus musculus

10 genes annotated in mouse

bronchus development

The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "bronchus development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "bronchus development" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.985
Gli2	GLI-Kruppel family member GLI2	0.982
Gli3	GLI-Kruppel family member GLI3	0.949
Fgfr2	fibroblast growth factor receptor 2	0.905
Pax2	paired box gene 2	0.904
Hoxb5	homeobox B5	0.860	Mouse
Rarg	retinoic acid receptor, gamma	0.755
Hoxa5	homeobox A5	0.723
Twist2	twist homolog 2 (Drosophila)	0.701
Hoxb6	homeobox B6	0.690	Mouse
Fgf8	fibroblast growth factor 8	0.678
Tcfap2a	transcription factor AP-2, alpha	0.661
Meox2	mesenchyme homeobox 2	0.649
Wnt4	wingless-related MMTV integration site 4	0.627	Mouse
Foxc1	forkhead box C1	0.619
Pax3	paired box gene 3	0.605
Smad4	MAD homolog 4 (Drosophila)	0.605
Lhx1	LIM homeobox protein 1	0.560
Rara	retinoic acid receptor, alpha	0.552
Gdnf	glial cell line derived neurotrophic factor	0.542
Hoxb3	homeobox B3	0.528
Rarb	retinoic acid receptor, beta	0.503
Tgfbr2	transforming growth factor, beta receptor II	0.474
Hoxd9	homeobox D9	0.456
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.453
Hoxa2	homeobox A2	0.449
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.429
Fgf10	fibroblast growth factor 10	0.424
Hoxc5	homeobox C5	0.417	Mouse
Hoxb4	homeobox B4	0.357	Mouse
Hoxc8	homeobox C8	0.346	Mouse
Sox9	SRY-box containing gene 9	0.341
Hoxa10	homeobox A10	0.336
Hoxd3	homeobox D3	0.305
Wnt6	wingless-related MMTV integration site 6	0.285	Mouse
Emx2	empty spiracles homolog 2 (Drosophila)	0.281
Bmp7	bone morphogenetic protein 7	0.265
Pbx1	pre B-cell leukemia transcription factor 1	0.261
Pax8	paired box gene 8	0.238
Otx2	orthodenticle homolog 2 (Drosophila)	0.231
Smo	smoothened homolog (Drosophila)	0.225
Hoxb9	homeobox B9	0.224
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.223
Hoxd13	homeobox D13	0.209
Wt1	Wilms tumor 1 homolog	0.201
Sox7	SRY-box containing gene 7	0.195	Mouse
Hoxa3	homeobox A3	0.190
Tbx2	T-box 2	0.179
Pou3f3	POU domain, class 3, transcription factor 3	0.175
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.174
Hoxc6	homeobox C6	0.170	Mouse
Hoxa9	homeobox A9	0.159
Hoxc4	homeobox C4	0.155	Mouse
Hoxb8	homeobox B8	0.154	Mouse
Apc	adenomatosis polyposis coli	0.150
Hoxa1	homeobox A1	0.147
Hoxd4	homeobox D4	0.139	Mouse
Gdf11	growth differentiation factor 11	0.136
Isl1	ISL1 transcription factor, LIM/homeodomain	0.135
Hhex	hematopoietically expressed homeobox	0.114
Hoxa4	homeobox A4	0.113	Mouse
Nog	noggin	0.110
Tcfap2c	transcription factor AP-2, gamma	0.104
Foxd2	forkhead box D2	0.099
Fgfr3	fibroblast growth factor receptor 3	0.098
Smad6	MAD homolog 6 (Drosophila)	0.096
Ret	ret proto-oncogene	0.092
Hoxd8	homeobox D8	0.089	Mouse
Gli1	GLI-Kruppel family member GLI1	0.088
Smad3	MAD homolog 3 (Drosophila)	0.084
Bnc1	basonuclin 1	0.082
Tcf21	transcription factor 21	0.079
Prrx2	paired related homeobox 2	0.078
Zfp503	zinc finger protein 503	0.076
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.075
Nodal	nodal	0.074
Hoxd11	homeobox D11	0.074
Cldn4	claudin 4	0.069
Fzd8	frizzled homolog 8 (Drosophila)	0.069
En1	engrailed 1	0.068
Bptf	bromodomain PHD finger transcription factor	0.067
Nkx2-1	NK2 homeobox 1	0.067
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.066
Hoxc9	homeobox C9	0.064
Nf1	neurofibromatosis 1	0.064
Hoxa7	homeobox A7	0.063	Mouse
Foxa2	forkhead box A2	0.062
Bmp4	bone morphogenetic protein 4	0.062	Human
Dhh	desert hedgehog	0.062
Hoxa11	homeobox A11	0.060
Tbx1	T-box 1	0.060
Hoxd10	homeobox D10	0.057
Rab25	RAB25, member RAS oncogene family	0.056
Gata4	GATA binding protein 4	0.055
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.054
Foxf1a	forkhead box F1a	0.054
Wnt3a	wingless-related MMTV integration site 3A	0.053	Mouse
Acvr1	activin A receptor, type 1	0.051	Mouse
Sox17	SRY-box containing gene 17	0.049	Mouse
Ebf3	early B-cell factor 3	0.049
Barx2	BarH-like homeobox 2	0.049
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.049	Mouse
Ephb2	Eph receptor B2	0.048
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.047
Hes1	hairy and enhancer of split 1 (Drosophila)	0.047
Hoxb2	homeobox B2	0.047
Bmper	BMP-binding endothelial regulator	0.046
Fzd1	frizzled homolog 1 (Drosophila)	0.045
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.044
Otx1	orthodenticle homolog 1 (Drosophila)	0.043
Dlx5	distal-less homeobox 5	0.043
Ihh	Indian hedgehog	0.043
Pthlh	parathyroid hormone-like peptide	0.042
Cldn8	claudin 8	0.042
Aplnr	apelin receptor	0.041
Krt14	keratin 14	0.041
Hand1	heart and neural crest derivatives expressed transcript 1	0.041
Gbx2	gastrulation brain homeobox 2	0.041
Pou5f1	POU domain, class 5, transcription factor 1	0.039
Foxp1	forkhead box P1	0.039
Socs1	suppressor of cytokine signaling 1	0.038
Gpc3	glypican 3	0.038
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.038
Edar	ectodysplasin-A receptor	0.038
Ptch1	patched homolog 1	0.038
T	brachyury	0.038
Oit1	oncoprotein induced transcript 1	0.037
Prrx1	paired related homeobox 1	0.037
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.036
Ctnnb1	catenin (cadherin associated protein), beta 1	0.036
Col2a1	collagen, type II, alpha 1	0.035
Lrp2	low density lipoprotein receptor-related protein 2	0.035
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.035
Alx3	aristaless-like homeobox 3	0.035
Lhx9	LIM homeobox protein 9	0.034
Gata6	GATA binding protein 6	0.034
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.034
Tgfbr1	transforming growth factor, beta receptor I	0.034	Mouse
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.033
Sall3	sal-like 3 (Drosophila)	0.032
Smad1	MAD homolog 1 (Drosophila)	0.032
Cdh16	cadherin 16	0.032
Lmx1a	LIM homeobox transcription factor 1 alpha	0.032
Srebf2	sterol regulatory element binding factor 2	0.031
Ar	androgen receptor	0.031
Eng	endoglin	0.030
Fgfr1	fibroblast growth factor receptor 1	0.030
Cdh5	cadherin 5	0.030
Wnt10b	wingless related MMTV integration site 10b	0.030	Mouse
Uncx	UNC homeobox	0.030
Ctf1	cardiotrophin 1	0.029
Foxd1	forkhead box D1	0.029
Cdh3	cadherin 3	0.028
Gata2	GATA binding protein 2	0.028
Wnt2b	wingless related MMTV integration site 2b	0.027	Mouse
Bmp2	bone morphogenetic protein 2	0.027
Chrd	chordin	0.026
Tbx10	T-box 10	0.026
She	src homology 2 domain-containing transforming protein E	0.026
Foxp2	forkhead box P2	0.026	Mouse
Fgf18	fibroblast growth factor 18	0.026
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.026	Mouse
Foxc2	forkhead box C2	0.025
Pou3f1	POU domain, class 3, transcription factor 1	0.025
Epha4	Eph receptor A4	0.025
Hoxb7	homeobox B7	0.024	Mouse
Emx1	empty spiracles homolog 1 (Drosophila)	0.024
Col13a1	collagen, type XIII, alpha 1	0.024
Fgf15	fibroblast growth factor 15	0.024
Zfp185	zinc finger protein 185	0.023
Sox2	SRY-box containing gene 2	0.023	Mouse
Vegfa	vascular endothelial growth factor A	0.023
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.022
Fgf3	fibroblast growth factor 3	0.021
Efna4	ephrin A4	0.021
Trp53	transformation related protein 53	0.021
Clic3	chloride intracellular channel 3	0.021
Sox3	SRY-box containing gene 3	0.021	Mouse
Wnt7a	wingless-related MMTV integration site 7A	0.021	Mouse
Nrtn	neurturin	0.020
Pitx1	paired-like homeodomain transcription factor 1	0.020
Wnt11	wingless-related MMTV integration site 11	0.020	Mouse
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.020
Eya1	eyes absent 1 homolog (Drosophila)	0.020
Hic1	hypermethylated in cancer 1	0.020
Itga3	integrin alpha 3	0.020
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.019
Rxra	retinoid X receptor alpha	0.019
Krt17	keratin 17	0.019
Edn3	endothelin 3	0.019
Elf3	E74-like factor 3	0.019	Mouse
Wnt3	wingless-related MMTV integration site 3	0.019	Mouse
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.019
Inhbb	inhibin beta-B	0.019
Gata3	GATA binding protein 3	0.019
Fzd4	frizzled homolog 4 (Drosophila)	0.018
Tead3	TEA domain family member 3	0.018
Amh	anti-Mullerian hormone	0.018
Lef1	lymphoid enhancer binding factor 1	0.018
Col22a1	collagen, type XXII, alpha 1	0.018
Fzd6	frizzled homolog 6 (Drosophila)	0.017
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.017
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.017
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.017
Fxyd2	FXYD domain-containing ion transport regulator 2	0.017
Fgf2	fibroblast growth factor 2	0.017
Bmp15	bone morphogenetic protein 15	0.017
Erbb2ip	Erbb2 interacting protein	0.017
Msx1	homeobox, msh-like 1	0.017
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.016
Des	desmin	0.016
Gas1	growth arrest specific 1	0.016
Ednra	endothelin receptor type A	0.016
Col11a1	collagen, type XI, alpha 1	0.016
1600029D21Rik	RIKEN cDNA 1600029D21 gene	0.016
Meox1	mesenchyme homeobox 1	0.016
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.016
Tgfbr3	transforming growth factor, beta receptor III	0.016
Cldn5	claudin 5	0.016
Fzd10	frizzled homolog 10 (Drosophila)	0.016
Foxf2	forkhead box F2	0.016
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.016
Nrk	Nik related kinase	0.016
Hes5	hairy and enhancer of split 5 (Drosophila)	0.015
Efna5	ephrin A5	0.015
Krt13	keratin 13	0.015
Hoxb13	homeobox B13	0.015
Twist1	twist homolog 1 (Drosophila)	0.015
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.014
Tmprss2	transmembrane protease, serine 2	0.014
Pitx2	paired-like homeodomain transcription factor 2	0.014
Emid2	EMI domain containing 2	0.014
Nos3	nitric oxide synthase 3, endothelial cell	0.014
Tgif2	TGFB-induced factor homeobox 2	0.013
Slurp1	secreted Ly6/Plaur domain containing 1	0.013
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.013
Zfp771	zinc finger protein 771	0.013
Zfp36l2	zinc finger protein 36, C3H type-like 2	0.013
Wnt9a	wingless-type MMTV integration site 9A	0.013	Mouse
Fam83g	family with sequence similarity 83, member G	0.013
Adra2a	adrenergic receptor, alpha 2a	0.013
Zfp703	zinc finger protein 703	0.012
Lama1	laminin, alpha 1	0.012
Rem1	rad and gem related GTP binding protein 1	0.012
Nfe2l3	nuclear factor, erythroid derived 2, like 3	0.012
Adra2c	adrenergic receptor, alpha 2c	0.012
Syt8	synaptotagmin VIII	0.012
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.012
Scx	scleraxis	0.012
Fgf4	fibroblast growth factor 4	0.012
Dll4	delta-like 4 (Drosophila)	0.012
Cldn3	claudin 3	0.012
Zbtb7a	zinc finger and BTB domain containing 7a	0.012
Smad7	MAD homolog 7 (Drosophila)	0.012
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.012
Smad5	MAD homolog 5 (Drosophila)	0.012
Acan	aggrecan	0.012
Rspo1	R-spondin homolog (Xenopus laevis)	0.011
Acvrl1	activin A receptor, type II-like 1	0.011	Mouse
Sim2	single-minded homolog 2 (Drosophila)	0.011
Aff1	AF4/FMR2 family, member 1	0.011
Sfn	stratifin	0.011
Muc4	mucin 4	0.011
Lgals7	lectin, galactose binding, soluble 7	0.011
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.011
Pofut1	protein O-fucosyltransferase 1	0.011
Creb1	cAMP responsive element binding protein 1	0.011
Col4a4	collagen, type IV, alpha 4	0.011
Upk3b	uroplakin 3B	0.011
Hmx3	H6 homeobox 3	0.010
Pgr	progesterone receptor	0.010
Meis1	Meis homeobox 1	0.010
Hand2	heart and neural crest derivatives expressed transcript 2	0.010
Ptrf	polymerase I and transcript release factor	0.010
Crlf1	cytokine receptor-like factor 1	0.010
Tbx3	T-box 3	0.010