IMP
Process View
ripoptosome assembly involved in necroptotic process
The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process.
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Click on a gene's description to view its network relationships with genes known to be involved in "ripoptosome assembly involved in necroptotic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ikbkg | inhibitor of kappaB kinase gamma | 1.000 | ||
| Traf6 | TNF receptor-associated factor 6 | 1.000 | ||
| Casp8 | caspase 8 | 0.999 | ||
| Traf2 | TNF receptor-associated factor 2 | 0.997 | ||
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.993 | ||
| Itch | itchy, E3 ubiquitin protein ligase | 0.981 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.980 | ||
| Myd88 | myeloid differentiation primary response gene 88 | 0.958 | ||
| Ikbkb | inhibitor of kappaB kinase beta | 0.874 | ||
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.737 | ||
| Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.668 | ||
| Tgfbr1 | transforming growth factor, beta receptor I | 0.541 | ||
| Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.522 | ||
| Cyld | cylindromatosis (turban tumor syndrome) | 0.464 | ||
| Tlr2 | toll-like receptor 2 | 0.382 | ||
| Tlr4 | toll-like receptor 4 | 0.285 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.246 | ||
| Il6st | interleukin 6 signal transducer | 0.239 | ||
| Hccs | holocytochrome c synthetase | 0.230 | ||
| Tuba1a | tubulin, alpha 1A | 0.202 | ||
| Tax1bp1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.171 | ||
| Naip6 | NLR family, apoptosis inhibitory protein 6 | 0.153 | Mouse | |
| Naip2 | NLR family, apoptosis inhibitory protein 2 | 0.133 | ||
| Chuk | conserved helix-loop-helix ubiquitous kinase | 0.133 | ||
| Naip5 | NLR family, apoptosis inhibitory protein 5 | 0.119 | Mouse | |
| Cd44 | CD44 antigen | 0.117 | ||
| Skil | SKI-like | 0.111 | ||
| Diablo | diablo homolog (Drosophila) | 0.098 | ||
| Map3k2 | mitogen-activated protein kinase kinase kinase 2 | 0.083 | ||
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.077 | ||
| Ripk3 | receptor-interacting serine-threonine kinase 3 | 0.071 | Mouse | |
| Cflar | CASP8 and FADD-like apoptosis regulator | 0.065 | ||
| Pten | phosphatase and tensin homolog | 0.060 | ||
| Trp53 | transformation related protein 53 | 0.058 | ||
| Ahr | aryl-hydrocarbon receptor | 0.056 | ||
| Fadd | Fas (TNFRSF6)-associated via death domain | 0.053 | ||
| Tcra | T-cell receptor alpha chain | 0.041 | ||
| Tex264 | testis expressed gene 264 | 0.040 | ||
| Pik3c2a | phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide | 0.038 | ||
| Zufsp | zinc finger with UFM1-specific peptidase domain | 0.036 | ||
| Tom1 | target of myb1 homolog (chicken) | 0.031 | ||
| Cd40 | CD40 antigen | 0.030 | ||
| Slfn2 | schlafen 2 | 0.030 | ||
| Stat4 | signal transducer and activator of transcription 4 | 0.030 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.028 | ||
| Irak3 | interleukin-1 receptor-associated kinase 3 | 0.028 | ||
| Ly96 | lymphocyte antigen 96 | 0.027 | ||
| Ubc | ubiquitin C | 0.026 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.025 | ||
| Cd86 | CD86 antigen | 0.025 | ||
| Kitl | kit ligand | 0.025 | ||
| Aldh2 | aldehyde dehydrogenase 2, mitochondrial | 0.024 | ||
| Rsph3b | radial spoke 3B homolog (Chlamydomonas) | 0.021 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.020 | ||
| Abcb4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 | 0.020 | ||
| Mlkl | mixed lineage kinase domain-like | 0.019 | ||
| Esrp1 | epithelial splicing regulatory protein 1 | 0.019 | ||
| Irak1 | interleukin-1 receptor-associated kinase 1 | 0.019 | ||
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.018 | ||
| Sqstm1 | sequestosome 1 | 0.017 | ||
| Ern1 | endoplasmic reticulum (ER) to nucleus signalling 1 | 0.017 | ||
| Il18rap | interleukin 18 receptor accessory protein | 0.017 | ||
| Bckdha | branched chain ketoacid dehydrogenase E1, alpha polypeptide | 0.016 | ||
| Hspa1b | heat shock protein 1B | 0.016 | ||
| Lpxn | leupaxin | 0.016 | ||
| Malt1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.015 | ||
| Pik3ap1 | phosphoinositide-3-kinase adaptor protein 1 | 0.015 | ||
| Foxp3 | forkhead box P3 | 0.015 | ||
| Map3k1 | mitogen-activated protein kinase kinase kinase 1 | 0.015 | ||
| Lcor | ligand dependent nuclear receptor corepressor | 0.015 | ||
| Ifnar1 | interferon (alpha and beta) receptor 1 | 0.015 | ||
| Nfkbiz | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.014 | ||
| Aim2 | absent in melanoma 2 | 0.014 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.013 | ||
| Dsg4 | desmoglein 4 | 0.013 | ||
| Rabac1 | Rab acceptor 1 (prenylated) | 0.013 | ||
| Birc3 | baculoviral IAP repeat-containing 3 | 0.013 | Mouse | |
| Sfn | stratifin | 0.012 | ||
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.012 | ||
| Tab1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | 0.012 | ||
| Tifa | TRAF-interacting protein with forkhead-associated domain | 0.012 | ||
| Irf6 | interferon regulatory factor 6 | 0.012 | ||
| Trim30d | tripartite motif-containing 30D | 0.011 | ||
| Cd38 | CD38 antigen | 0.011 | ||
| Dnajc4 | DnaJ (Hsp40) homolog, subfamily C, member 4 | 0.011 | ||
| Rnf31 | ring finger protein 31 | 0.011 | ||
| Rgs1 | regulator of G-protein signaling 1 | 0.011 | ||
| Smad1 | MAD homolog 1 (Drosophila) | 0.011 | ||
| Stx11 | syntaxin 11 | 0.010 | ||
| Slc37a4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.010 |