IMP

Process View

Danio rerio

3 genes annotated in zebrafish

facial nerve development

The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "facial nerve development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "facial nerve development" (in gray)

Name	Description	Probability	Func Analog Organism
hoxb1a	homeo box B1a	0.984
sema3d	semaphorin 3d	0.963
dla	deltaA	0.956
hoxb2a	homeo box B2a	0.939	Zebrafish Mouse
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.872
nrp1a	neuropilin 1a	0.826	Mouse
egr2b	early growth response 2b	0.791	Mouse
hoxb3a	homeo box B3a	0.632
dld	deltaD	0.618
boc	brother of CDO	0.582
mib	mind bomb	0.578
lhx3	LIM homeobox 3	0.522
gli2a	GLI-Kruppel family member GLI2a	0.506	Zebrafish
hoxa2b	homeo box A2b	0.477	Zebrafish
hoxb6a	homeo box B6a	0.429
nrp1b	neuropilin 1b	0.423	Mouse
crestin	crestin	0.373
efnb3b	ephrin B3b	0.371
wu:fv91b12	wu:fv91b12	0.344
itga5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.311
irx3b	iroquois homeobox protein 3b	0.267
efnb1	ephrin B1	0.263
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.238
plxna3	plexin A3	0.236	Mouse
pcdh18b	protocadherin 18b	0.205
antxr1	anthrax toxin receptor 1	0.191
hoxa3a	homeo box A3a	0.191
sox10	SRY-box containing gene 10	0.187
foxd3	forkhead box D3	0.184
phox2a	paired-like homeobox 2a	0.181
disp1	dispatched homolog 1 (Drosophila)	0.177
scube2	signal peptide, CUB domain, EGF-like 2	0.174
dzip1	DAZ interacting protein 1	0.172
ntn1b	netrin 1b	0.168
btg2	B-cell translocation gene 2	0.159
rest	RE1-silencing transcription factor	0.156
wnt5b	wingless-type MMTV integration site family, member 5b	0.154
epha4a	eph receptor A4a	0.153
egr2a	early growth response 2a	0.151	Mouse
nrp2b	neuropilin 2b	0.145	Mouse
hoxb1b	homeo box B1b	0.132	Zebrafish Mouse
hoxd3a	homeo box D3a	0.130
egr1	early growth response 1	0.128
tbx24	T-box 24	0.126
flncb	filamin C, gamma b (actin binding protein 280)	0.123
twist1a	twist1a	0.117
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.108
efnb2a	ephrin B2a	0.107
efna2	ephrin A2	0.105
traf4a	tnf receptor-associated factor 4a	0.096
cntn2	contactin 2	0.095
hoxa5a	homeo box A5a	0.085
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.083
meis2.2	myeloid ecotropic viral integration site 2.2	0.079
gfra1a	gdnf family receptor alpha 1a	0.076
prickle1b	prickle homolog 1 (Drosophila) b	0.075
nav3	neuron navigator 3	0.073
esrrga	estrogen-related receptor gamma a	0.072
hsp90a.1	heat shock protein 90-alpha 1	0.072
twist1b	twist1b	0.068
hoxc1a	homeo box C1a	0.067	Zebrafish
fn1	fibronectin 1	0.066
hspa12b	heat shock protein 12B	0.064
nadl1.1	neural adhesion molecule L1.1	0.063
dusp5	dual specificity phosphatase 5	0.063
chrna4	cholinergic receptor, nicotinic, alpha 4	0.062
smad1	MAD homolog 1 (Drosophila)	0.062
nhsl1b	NHS-like 1b	0.057
dpysl2b	dihydropyrimidinase-like 2b	0.056
hapln1a	hyaluronan and proteoglycan link protein 1a	0.052
angpt1	angiopoietin 1	0.052
epb4.1l4	erythrocyte protein band 4.1-like 4	0.051
ephb3a	eph receptor B3a	0.051
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.049
insm1a	insulinoma-associated 1a	0.049
sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.048
vangl2	vang-like 2 (van gogh, Drosophila)	0.048
pax7b	paired box gene 7b	0.048
edn1	endothelin 1	0.048
ephb4a	eph receptor B4a	0.047
flt4	fms-related tyrosine kinase 4	0.046
gli1	GLI-Kruppel family member 1	0.046
onecutl	one cut domain, family member, like	0.046
pbx4	pre-B-cell leukemia transcription factor 4	0.045
plagl2	pleiomorphic adenoma gene-like 2	0.045
six1a	sine oculis homeobox homolog 1a	0.044	Mouse
lamb1a	laminin, beta 1a	0.044
ptch1	patched 1	0.042
pax7a	paired box gene 7a	0.042
notch1a	notch homolog 1a	0.041
vegfc	vascular endothelial growth factor c	0.041
meis4.1a	myeloid ecotropic viral integration site 4.1a	0.041
plxna4	plexin A4	0.041	Mouse
si:dkeyp-63d11.7	si:dkeyp-63d11.7	0.040
fstl1b	follistatin-like 1b	0.040
ndr2	nodal-related 2	0.040
jam2b	junctional adhesion molecule 2b	0.040
tnc	tenascin C	0.039
lmo4a	LIM domain only 4a	0.038
hoxb6b	homeo box B6b	0.038
epha7	eph receptor A7	0.036
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.035
skia	nuclear oncoprotein skia	0.034
irx5b	iroquois homeobox protein 5b	0.034
nrp2a	neuropilin 2a	0.033	Mouse
pdzrn3	PDZ domain containing RING finger 3 and PDZ domain containing ring finger 3	0.032
drd2l	dopamine receptor D2 like	0.031
six4b	sine oculis homeobox homolog 4b	0.030
ddx26b	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B	0.029
smoc1	SPARC related modular calcium binding 1	0.029
zic4	zic family member 4	0.028
hoxa1a	homeo box A1a	0.028	Zebrafish Mouse
wnt3a	wingless-type MMTV integration site family, member 3A	0.028
six4a	sine oculis homeobox homolog 4a	0.028
myf5	myogenic factor 5	0.028
tbx1	T-box 1	0.027
tlx2	T-cell leukemia, homeobox 2	0.027
efna5b	ephrin A5b	0.027
nr4a3	nuclear receptor subfamily 4, group A, member 3	0.026
par1	paraxis	0.026
sf3b1	splicing factor 3b, subunit 1	0.025
id:ibd2808	id:ibd2808	0.025
dmrta2	doublesex and mab-3 related transcription factor like family A2	0.024
vasp	vasodilator-stimulated phosphoprotein	0.024
sb:cb81	sb:cb81	0.024
dusp2	dual specificity phosphatase 2	0.024
sb:cb774	sb:cb774	0.024
irx7	iroquois homeobox protein 7	0.023
sema3c	semaphorin 3c	0.023
asb2b	ankyrin repeat and SOCS box-containing 2b	0.023
flot1	flotillin 1	0.023
zgc:85866	zgc:85866	0.022
meis3	myeloid ecotropic viral integration site 3	0.022
raraa	retinoic acid receptor, alpha a	0.022
myo15aa	myosin XVAa	0.022
arx	aristaless related homeobox	0.022
drd3	dopamine receptor D3	0.022
sema3aa	semaphorin 3aa	0.022	Mouse
esrrb	estrogen-related receptor beta	0.021
sema3gb	semaphorin 3gb	0.021
nkx3.2	NK3 homeobox 2	0.021
jag1a	jagged 1a	0.021
cart1	cartilage paired-class homeoprotein 1	0.021
mef2cb	myocyte enhancer factor 2cb	0.020
foxi1	forkhead box I1	0.020
six2a	sine oculis-related homeobox 2a	0.020
esrrgb	estrogen-related receptor gamma b	0.020
slit3	slit (Drosophila) homolog 3	0.020
nkx2.3	NK2 transcription factor related 3	0.020
rapsn	receptor-associated protein of the synapse, 43kD	0.020
mef2d	myocyte enhancer factor 2d	0.020
tbx16	T-box gene 16	0.019
pax3b	paired box gene 3b	0.019
zgc:85939	zgc:85939	0.019
nrg2a	neuregulin 2a	0.019
gfra1b	gdnf family receptor alpha 1b	0.019
alx4a	aristaless-like homeobox 4a	0.018
gli2b	GLI-Kruppel family member GLI2b	0.018
oep	one-eyed pinhead	0.018
mecom	MDS1 and EVI1 complex locus	0.018
nog2	noggin 2	0.018
zgc:110298	zgc:110298	0.018
zgc:136866	zgc:136866	0.018
hoxb8b	homeo box B8b	0.018
hdac4	histone deacetylase 4	0.018
zgc:92218	zgc:92218	0.018
phox2b	paired-like homeobox 2b	0.018
hoxa11a	homeo box A11a	0.018
irx1b	iroquois homeobox protein 1, b	0.018
gbx1	gastrulation brain homeobox 1	0.018
tbx18	T-box 18	0.018
znf536	zinc finger protein 536	0.017
nr4a2b	nuclear receptor subfamily 4, group A, member 2b	0.017
grhl2b	grainyhead-like 2b (Drosophila)	0.017
plekhh1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	0.017
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.017
chrnd	cholinergic receptor, nicotinic, delta polypeptide	0.017
sema3fb	semaphorin 3fb	0.017	Mouse
nova2	neuro-oncological ventral antigen 2	0.017
sox9a	SRY-box containing gene 9a	0.016
gsx1	GS homeobox 1	0.016
plod2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.016
ntn1a	netrin 1a	0.016
fstl1a	follistatin-like 1a	0.016
chst11	carbohydrate (chondroitin 4) sulfotransferase 11	0.016
lhx9	LIM homeobox 9	0.016
atoh1a	atonal homolog 1a	0.016
hic1	hypermethylated in cancer 1	0.016
ret1	receptor tyrosine kinase	0.016
prpf8	pre-mRNA processing factor 8	0.016
sema3ab	semaphorin 3ab	0.015	Mouse
pea3	ETS-domain transcription factor pea3	0.015
emx3	empty spiracles homeobox 3	0.015
szl	sizzled	0.015
ltk	leukocyte tyrosine kinase	0.015
zbtb16a	zinc finger and BTB domain containing 16a	0.015
hoxb5b	homeo box B5b	0.015
smyhc1l	slow myosin heavy chain 1, like	0.014
her8a	hairy-related 8a	0.014
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.014
p2rx3a	purinergic receptor P2X, ligand-gated ion channel, 3a	0.014
fgf5	fibroblast growth factor 5	0.014
fscn1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)	0.014
cyb5d1	cytochrome b5 domain containing 1	0.014
ache	acetylcholinesterase	0.014
im:7162646	im:7162646	0.014
zwi	zwilling	0.014
zgc:136894	zgc:136894	0.014
myf6	myogenic factor 6	0.014
rpl10a	ribosomal protein L10a	0.014
cdh10	cadherin 10, type 2 (T2-cadherin)	0.014
eng1b	engrailed 1b	0.013
pnx	posterior neuron-specific homeobox	0.013
nfasca	neurofascin homolog (chicken) a	0.013
dlc	deltaC	0.013
zgc:153061	zgc:153061	0.013
znf703	zinc finger protein 703	0.013
tmem2	transmembrane protein 2	0.013
cacnb3a	calcium channel, voltage-dependent, beta 3a	0.013
hoxc6a	homeo box C6a	0.013
cenph	centromere protein H	0.013
im:7138629	im:7138629	0.013
hoxb4a	homeo box B4a	0.013
LOC569779	Heavy chain, Unconventional Myosin family member (hum-6)-like	0.013
rb1	retinoblastoma 1	0.013
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.013
pax8	paired box gene 8	0.013
zgc:103545	zgc:103545	0.013
rfng	radical fringe homolog (Drosophila)	0.013
extl3	exostoses (multiple)-like 3	0.013
sulf1	sulfatase 1	0.012
hoxd4a	homeo box D4a	0.012
hlxb9lb	homeo box HB9 like b	0.012
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.012
hoxc10a	homeo box C10a and homeobox protein Hox-C10a-like	0.012
disc1	disrupted in schizophrenia 1	0.012
myst3	MYST histone acetyltransferase (monocytic leukemia) 3	0.012
hhip	hedgehog interacting protein	0.012
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.012
dbx1b	developing brain homeobox 1b	0.012
ptrfb	polymerase I and transcript release factor b	0.012
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.012
zeb2b	zinc finger E-box binding homeobox 2b	0.012
tfap2a	transcription factor AP-2 alpha	0.012
fzd9b	frizzled homolog 9b	0.012
kirrela	kin of IRRE like a	0.012
sox4b	SRY-box containing gene 4b	0.011
si:ch211-197h24.9	si:ch211-197h24.9	0.011
supt6h	suppressor of Ty 6 homolog	0.011
fli1b	friend leukemia integration 1b	0.011
mef2ca	myocyte enhancer factor 2ca	0.011
pcdh10a	protocadherin 10a	0.011
isl2a	islet2a	0.011
mcamb	melanoma cell adhesion molecule b	0.011
plod1a	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a	0.011
sim1a	single-minded homolog 1a (Drosophila)	0.011
ints6	integrator complex subunit 6	0.011
hand2	heart and neural crest derivatives expressed transcript 2	0.011
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.011
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.011
p2rx3b	purinergic receptor P2X, ligand-gated ion channel, 3b	0.011
zgc:162967	zgc:162967	0.010
zgc:112992	zgc:112992	0.010
fzd2	frizzled homolog 2	0.010
veph	ventricular zone expressed PH domain protein	0.010
col6a6	collagen, type VI, alpha 6	0.010
uncx4.1	Unc4.1 homeobox (C. elegans)	0.010
nrip1b	nuclear receptor interacting protein 1b	0.010