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Process View

Danio rerio

12 genes annotated in zebrafish

syncytium formation

The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "syncytium formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "syncytium formation" (in gray)

Name	Description	Probability	Func Analog Organism
myod1	myogenic differentiation 1	0.768	Human Mouse
dcc	deleted in colorectal carcinoma	0.766
mef2ca	myocyte enhancer factor 2ca	0.457	Fly
jam2a	junctional adhesion molecule 2a	0.451
gpia	glucose phosphate isomerase a	0.421
kirrel3l	kin of IRRE like 3 like	0.355
btk	Bruton agammaglobulinemia tyrosine kinase	0.262
jam3b	junctional adhesion molecule 3b	0.255
hsp90a.1	heat shock protein 90-alpha 1	0.246
frmd6	FERM domain containing 6	0.176
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.161
aldocb	aldolase C, fructose-bisphosphate, b	0.151
dock1	dedicator of cytokinesis 1	0.131
rbfox1l	RNA binding protein, fox-1 homolog (C. elegans) 1-like	0.129
rogdi	rogdi homolog (Drosophila)	0.122
mef2d	myocyte enhancer factor 2d	0.114	Fly
atp6v1b2	ATPase, H+ transporting, lysosomal V1 subunit B2	0.112	Worm
llgl2	lethal giant larvae homolog 2 (Drosophila)	0.110
wu:fv91b12	wu:fv91b12	0.108
atp6v1ba	ATPase, H+ transporting, lysosomal, V1 subunit B, member a	0.099	Worm
wtip	Wilms tumor 1 interacting protein	0.095
vegfab	vascular endothelial growth factor Ab	0.094
foxo3b	forkhead box O3b	0.091	Fly
hoxa11a	homeo box A11a	0.090
flot1b	flotillin 1b	0.089
lrrc33	leucine rich repeat containing 33	0.089
spry4	sprouty (Drosophila) homolog 4	0.088
ndfip1	Nedd4 family interacting protein 1	0.085
ckbb	creatine kinase, brain b	0.084
pak2a	p21 (CDKN1A)-activated kinase 2a	0.080
ptk2.1	protein tyrosine kinase 2a	0.077
nphs1l	nephrosis 1, congenital, Finnish type (nephrin)-like	0.077	Mouse Fly
colec11	collectin sub-family member 11	0.076
mmp9	matrix metalloproteinase 9	0.076
si:dkey-27i16.2	si:dkey-27i16.2	0.075
jag2	jagged 2	0.072
atp6v1d	ATPase, H+ transporting, V1 subunit D and ATPase, H+ transporting, V1 subunit D	0.070
prrx1b	paired related homeobox 1b	0.068
ttna	titin a	0.068
wt1b	wilms tumor 1b	0.065
meox1	mesenchyme homeobox 1	0.063
desma	desmin a	0.060
LOC566969	similar to MOX-2 protein	0.059
boc	brother of CDO	0.056
stac3	SH3 and cysteine rich domain 3	0.054
lyz	lysozyme	0.054
insrb	insulin receptor b	0.054	Fly
isl1	islet1	0.053
f11r	F11 receptor	0.052	Zebrafish
efnb2a	ephrin B2a	0.051
plxnb2a	plexin b2a	0.051
atp6v1g1	ATPase, H+ transporting, V1 subunit G isoform 1	0.050
cxadr	coxsackie virus and adenovirus receptor	0.048
laptm4b	lysosomal associated protein transmembrane 4 beta	0.047
neurod	neurogenic differentiation	0.046
ldb1a	LIM-domain binding factor 1a	0.046
arfip2a	ADP-ribosylation factor interacting protein 2a	0.045
pfn1	profilin 1	0.044
lbx2	ladybird homeobox homolog 2 (Drosophila)	0.043	Fly
plce1	phospholipase C, epsilon 1	0.043
mxi1	max interacting protein	0.042
vgll2b	vestigial like 2b	0.041
tpm4	tropomyosin 4	0.041
gapdhs	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.040
csf3r	colony stimulating factor 3 receptor (granulocyte)	0.039
cdh1	cadherin 1, epithelial	0.039
vegfaa	vascular endothelial growth factor Aa	0.039
ptpra	protein tyrosine phosphatase, receptor type, A	0.039
dock5	dedicator of cytokinesis 5	0.038
ryr1b	ryanodine receptor 1b (skeletal)	0.037
jup	junction plakoglobin	0.037
spon1b	spondin 1b	0.036
myca	myelocytomatosis oncogene a	0.035
tpm3	tropomyosin 3	0.034
ldb2a	LIM-domain binding factor 2a	0.034
tcf12	transcription factor 12	0.034
bmp4	bone morphogenetic protein 4	0.033
spi1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.032
zbtb4	zinc finger and BTB domain containing 4	0.032
nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.031
coro1a	coronin, actin binding protein, 1A	0.031
atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	0.030
calm1b	calmodulin 1b	0.029
smyd1b	SET and MYND domain containing 1b	0.028
cyt1	type I cytokeratin, enveloping layer	0.028
efnb3b	ephrin B3b	0.027
olig4	oligodendrocyte transcription factor 4	0.026
rtn1a	reticulon 1a	0.026
camk2d2	calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2	0.026
zgc:55813	zgc:55813	0.026
zgc:112257	zgc:112257	0.025
fmr1	fragile X mental retardation 1	0.025
hhatla	hedgehog acyltransferase-like, a	0.025
atp6v1e1b	ATPase, H+ transporting, lysosomal, V1 subunit E isoform 1b	0.025
gmfg	glia maturation factor, gamma	0.024
si:dkey-204a24.9	si:dkey-204a24.9	0.024
crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.024
lhx9	LIM homeobox 9	0.024
flncb	filamin C, gamma b (actin binding protein 280)	0.024
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.023
myhc4	myosin heavy chain 4	0.023
atp6v0d1	ATPase, H+ transporting, V0 subunit D isoform 1	0.023
myog	myogenin	0.023	Mouse
tsc22d2	TSC22 domain family 2 and TSC22 domain family, member 2	0.023
mnx1	motor neuron and pancreas homeobox 1	0.022
antxr1	anthrax toxin receptor 1	0.022
prox1	prospero-related homeobox gene 1	0.022
mmp15a	matrix metallopeptidase 15a	0.022
zgc:112180	zgc:112180	0.022
cxcl12a	chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)	0.021	Mouse
st14a	suppression of tumorigenicity 14 (colon carcinoma) a	0.021
crip2	cysteine-rich protein 2	0.021
ctsc	cathepsin C	0.020
sept8a	septin 8a	0.020
fcer1gl	Fc receptor, IgE, high affinity I, gamma polypeptide like	0.020
aldoaa	aldolase a, fructose-bisphosphate, a	0.020
ndrg3b	N-myc downstream regulated family member 3b	0.020
ppap2c	phosphatidic acid phosphatase type 2C	0.020
sema3aa	semaphorin 3aa	0.020
zgc:101523	zgc:101523	0.020
atp6v1h	ATPase, H+ transporting, lysosomal, V1 subunit H	0.020
axin2	axin 2 (conductin, axil)	0.020
glcci1	glucocorticoid induced transcript 1	0.019
nolc1	nucleolar and coiled-body phosphoprotein 1	0.019
vdac3	voltage-dependent anion channel 3	0.019
bmp2k	BMP2 inducible kinase	0.018
pea3	ETS-domain transcription factor pea3	0.018
kirrelb	kin of IRRE like b	0.018	Fly
zgc:92429	zgc:92429	0.018
slc9a3r1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.018
sypl2a	synaptophysin-like 2a	0.018
mapk1	mitogen-activated protein kinase 1	0.017
agtr2	angiotensin II receptor, type 2	0.017
clstn1	calsyntenin 1	0.017
dusp6	dual specificity phosphatase 6	0.017
efemp2	EGF-containing fibulin-like extracellular matrix protein 2	0.017
ap2b1	adaptor-related protein complex 2, beta 1 subunit	0.017
emp2	epithelial membrane protein 2	0.017
hoxa13b	homeo box A13b	0.017
mpp1	membrane protein, palmitoylated 1	0.017
rictor	RPTOR independent companion of MTOR, complex 2	0.017
cdc42	cell division cycle 42	0.017
zgc:63663	zgc:63663	0.017
si:dkey-19f21.3	si:dkey-19f21.3	0.016
zgc:91930	zgc:91930	0.016
thsd7a	thrombospondin, type I, domain containing 7A	0.016
zgc:136894	zgc:136894	0.016
dlst	dihydrolipoamide S-succinyltransferase	0.016
podxl	podocalyxin-like	0.016
ccbe1	collagen and calcium binding EGF domains 1	0.016
zgc:56116	zgc:56116	0.016
caspa	caspase a	0.016
hoxb5b	homeo box B5b	0.016
oclna	occludin a	0.016
mmp13a	matrix metalloproteinase 13a	0.016
lamb2	laminin, beta 2 (laminin S)	0.015
cyyr1	cysteine and tyrosine-rich protein 1	0.015
xirp1	xin actin-binding repeat containing 1	0.015
sox6	SRY-box containing gene 6	0.015
LOC556160	guanine nucleotide-binding protein subunit alpha-14-like	0.015
ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.015
si:dkeyp-22b2.3	si:dkeyp-22b2.3	0.015
zfp36l1a	zinc finger protein 36, C3H type-like 1a	0.015
hoxa11b	homeo box A11b	0.015
sb:cb930	sb:cb930	0.015
pkm2a	pyruvate kinase, muscle, a	0.015
dag1	dystroglycan 1	0.015
etv2	ets variant gene 2	0.015
tnfrsfa	tumor necrosis factor receptor superfamily, member a	0.015
si:dkey-233h2.3	si:dkey-233h2.3	0.015
col6a6	collagen, type VI, alpha 6	0.015
cnn3a	calponin 3, acidic a	0.015
yrk	Yes-related kinase	0.014
lgmn	legumain	0.014
dync1h1	dynein, cytoplasmic 1, heavy chain 1	0.014
myom1a	myomesin 1a (skelemin)	0.014
mpzl2	myelin protein zero-like 2	0.014
twist3	twist3	0.014
six1b	sine oculis homeobox homolog 1b	0.014
synpo2lb	synaptopodin 2-like b	0.014
dkk2	dickkopf homolog 2 (Xenopus laevis)	0.014
tp73	tumor protein p73	0.014
taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto	0.014
si:ch211-89p1.1	si:ch211-89p1.1	0.014
cnn2	calponin 2	0.014
tmem161b	transmembrane protein 161B	0.014
arpc1b	actin related protein 2/3 complex, subunit 1B	0.014
cx39.9	connexin 39.9	0.014
zgc:63523	zgc:63523	0.014
ryr1a	ryanodine receptor 1a (skeletal)	0.014
chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1	0.014
myf6	myogenic factor 6	0.014
si:dkey-222f8.3	si:dkey-222f8.3	0.014
glula	glutamate-ammonia ligase (glutamine synthase) a	0.013
ptprc	protein tyrosine phosphatase, receptor type, C	0.013
unc45b	unc-45 homolog B (C. elegans)	0.013
zgc:55573	zgc:55573	0.013
suv420h2	suppressor of variegation 4-20 homolog 2 (Drosophila)	0.013
lsr	lipolysis stimulated lipoprotein receptor	0.013
mst1rb	macrophage stimulating 1 receptor (c-met-related tyrosine kinase), b	0.013
rfx6	regulatory factor X, 6	0.013
krml2.2	Kreisler (mouse) maf-related leucine zipper homolog 2.2	0.013
heg	heart of glass	0.013
cmlc1	cardiac myosin light chain-1	0.013
tm4sf4	transmembrane 4 L six family member 4	0.013
ctsf	cathepsin F	0.013
met	met proto-oncogene (hepatocyte growth factor receptor)	0.013
epas1b	endothelial PAS domain protein 1b	0.013
akt2	v-akt murine thymoma viral oncogene homolog 2	0.013	Fly
arhgef1	rho guanine nucleotide exchange factor (GEF) 1	0.013
mpll	myeloproliferative leukemia virus oncogene, like	0.013
mxra8b	matrix-remodelling associated 8b	0.012
sh3gl2	SH3-domain GRB2-like 2	0.012
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.012
nr1h5	nuclear receptor subfamily 1, group H, member 5	0.012
tnikb	TRAF2 and NCK interacting kinase b	0.012
cdh15	cadherin 15, M-cadherin (myotubule)	0.012
vmhc	ventricular myosin heavy chain	0.012
spag1	sperm associated antigen 1	0.012
msi2b	musashi homolog 2b (Drosophila)	0.012
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.012
jam3a	junctional adhesion molecule 3a	0.012
mecp2	methyl CpG binding protein 2	0.012
sulf2l	sulfatase 2, like	0.012
crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.012
sh3bgrl3	SH3 domain binding glutamic acid-rich protein like 3	0.012
runx1	runt-related transcription factor 1	0.012
sp9	sp9 transcription factor	0.012
dscam	Down syndrome cell adhesion molecule	0.012
nnt	nicotinamide nucleotide transhydrogenase	0.012
zgc:101724	zgc:101724	0.012
zmynd11	zinc finger, MYND domain containing 11	0.011
angpt1	angiopoietin 1	0.011
ppme1	protein phosphatase methylesterase 1	0.011
fgfr1a	fibroblast growth factor receptor 1a	0.011
ogt.2	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 2	0.011
plagx	pleiomorphic adenoma gene X	0.011
gli3	GLI-Kruppel family member GLI3	0.011
gnb1a	guanine nucleotide binding protein (G protein), beta polypeptide 1a	0.011
pgk1	phosphoglycerate kinase 1	0.011
fyna	FYN oncogene related to SRC, FGR, YES a	0.011
npc1	Niemann-Pick disease, type C1	0.011
foxn1	forkhead box N1	0.011
chn1	chimerin (chimaerin) 1	0.011
stau2	staufen, RNA binding protein, homolog 2 (Drosophila)	0.011
jam2b	junctional adhesion molecule 2b	0.011
zeb2a	zinc finger E-box binding homeobox 2a	0.011
sst2	somatostatin 2	0.011
musk	muscle, skeletal, receptor tyrosine kinase	0.011
skia	nuclear oncoprotein skia	0.011
rhoq	ras homolog gene family, member Q	0.011
grna	granulin a	0.011
mapk12	mitogen-activated protein kinase 12	0.010
myhz2	myosin, heavy polypeptide 2, fast muscle specific	0.010
apobec2a	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a	0.010
olfm2	olfactomedin 2	0.010
zgc:100829	zgc:100829	0.010
lamp2	lysosomal membrane glycoprotein 2	0.010
appl1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.010
hs3st3b1a	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1a	0.010