IMP

Process View

Danio rerio

2 genes annotated in zebrafish

dopamine biosynthetic process

The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dopamine biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dopamine biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
mitfa	microphthalmia-associated transcription factor a	0.858
dct	dopachrome tautomerase	0.807	Zebrafish
th	tyrosine hydroxylase	0.728
slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.698
crh	corticotropin releasing hormone	0.554
cyp19a1b	cytochrome P450, family 19, subfamily A, polypeptide 1b	0.485
htr1aa	5-hydroxytryptamine (serotonin) receptor 1A a	0.362
ddc	dopa decarboxylase	0.286	Worm Fly
sox10	SRY-box containing gene 10	0.269
gch2	GTP cyclohydrolase 2	0.231	Worm
tyrp1	tyrosinase-related protein 1	0.226
ednrb1	endothelin receptor B	0.211
pnp4a	purine nucleoside phosphorylase 4a	0.184
LOC100006361	galanin-like	0.175
nr4a2b	nuclear receptor subfamily 4, group A, member 2b	0.169	Mouse
aox3	aldehyde oxidase 3	0.122
nos1	nitric oxide synthase 1 (neuronal)	0.117
grem2	gremlin 2, cysteine knot superfamily	0.106
pmela	premelanosome protein a	0.098
col9a2	procollagen, type IX, alpha 2	0.097
crhbp	corticotropin releasing hormone binding protein	0.094
coe2	coe2	0.083
dlx2a	distal-less homeobox gene 2a	0.081
csf1ra	colony stimulating factor 1 receptor, a	0.077
prom1b	prominin 1 b	0.074
lhx2b	LIM homeobox 2b	0.072
hbbe3	hemoglobin beta embryonic-3	0.070
dlx2b	distal-less homeobox gene 2b	0.068
tfec	transcription factor EC	0.067
crestin	crestin	0.065
barhl1.2	BarH-like 1.2	0.064
th2	tyrosine hydroxylase 2	0.056	Zebrafish Worm Fly
slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.055	Worm
tyrp1b	tyrosinase-related protein 1b	0.054	Zebrafish
ebf3	early B-cell factor 3	0.053
hcrt	hypocretin (orexin) neuropeptide precursor	0.052
si:dkey-24g18.2	si:dkey-24g18.2	0.050
zgc:91968	zgc:91968	0.049
fgf20b	fibroblast growth factor 20b	0.048
zgc:110784	zgc:110784	0.045
pax7a	paired box gene 7a	0.043
otpa	orthopedia homolog a	0.043
zgc:100919	zgc:100919	0.042
dlx4a	distal-less homeobox gene 4a	0.041
dlx5a	distal-less homeobox gene 5a	0.041
sst1.1	somatostatin 1, tandem duplicate 1	0.039
veph	ventricular zone expressed PH domain protein	0.038
hlx1	H2.0-like homeo box 1 (Drosophila)	0.038
sim1a	single-minded homolog 1a (Drosophila)	0.038
alx4b	aristaless-like homeobox 4b	0.038
adcyap1r1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	0.036
itgav	integrin, alpha V	0.036
phox2b	paired-like homeobox 2b	0.035
nme4	non-metastatic cells 4, protein expressed in	0.035
atp1a1a.2	ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide	0.034
tph2	tryptophan hydroxylase 2 (tryptophan 5-monooxygenase)	0.034	Zebrafish
cldng	claudin g	0.034
rgrb	retinal G protein coupled receptor b	0.033
foxi3b	forkhead box I3b	0.032
fev	FEV (ETS oncogene family)	0.032
myhz1.2	myosin, heavy polypeptide 1.2, skeletal muscle	0.031
opn4a	opsin 4a (melanopsin)	0.031
zgc:110789	zgc:110789	0.031
slc2a15b	solute carrier family 2 (facilitated glucose transporter), member 15b	0.031
uros	uroporphyrinogen III synthase	0.030
dera	2-deoxyribose-5-phosphate aldolase homolog (C. elegans)	0.030
barhl1.1	BarH-like 1.1	0.028
col5a3	collagen, type V, alpha 3	0.028
gstt1a	glutathione S-transferase theta 1a	0.027
dlx6a	distal-less homeobox gene 6a	0.025
oprd1b	opioid receptor, delta 1b	0.025
dbh	dopamine beta hydroxylase	0.025
nr4a3	nuclear receptor subfamily 4, group A, member 3	0.025
hoxa13b	homeo box A13b	0.024
prox1	prospero-related homeobox gene 1	0.023
grm5a	glutamate receptor, metabotropic 5a	0.023
ptf1a	pancreas specific transcription factor, 1a	0.023
fhl2a	four and a half LIM domains 2a	0.023
syngr1a	synaptogyrin 1a	0.022
lepr	leptin receptor	0.022
alas2	aminolevulinate, delta-, synthetase 2	0.022
dlx1a	distal-less homeobox gene 1a	0.021
kita	kit receptor a	0.021
myl1	myosin, light chain 1, alkali; skeletal, fast	0.021
gpr143	G protein-coupled receptor 143	0.021
slc45a2	solute carrier family 45, member 2	0.021
zgc:110124	zgc:110124	0.021
vps39	vacuolar protein sorting 39 homolog (S. cerevisiae)	0.020
msxa	muscle segment homeobox A	0.020
htr1bd	5-hydroxytryptamine (serotonin) receptor 1bd	0.020
slc6a4a	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4A	0.020
hcrtr2	hypocretin (orexin) receptor 2	0.020
roraa	RAR-related orphan receptor A, paralog a	0.020
tcf4	transcription factor 4	0.019
cadm4	cell adhesion molecule 4	0.019
htr1ab	5-hydroxytryptamine (serotonin) receptor 1A b	0.019
si:dkey-228g21.4	si:dkey-228g21.4	0.019
rxfp1	relaxin/insulin-like family peptide receptor 1	0.019
nrp1b	neuropilin 1b	0.019
tnnc1a	troponin C type 1a (slow)	0.019
hbaa1	hemoglobin alpha adult-1	0.018
slc6a4b	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4B	0.018
dtnbp1a	dystrobrevin binding protein 1a	0.018
prdx2	peroxiredoxin 2	0.018
esr1	estrogen receptor 1	0.018
sod1	superoxide dismutase 1, soluble	0.017
lhx6	LIM homeobox 6	0.017
foxp2	forkhead box P2	0.017
foxa1	forkhead box A1	0.017
sema3gb	semaphorin 3gb	0.017
urod	uroporphyrinogen decarboxylase	0.016
ghrl	ghrelin/obestatin preprohormone	0.016
ftcd	formiminotransferase cyclodeaminase	0.016
si:ch211-222e23.2	si:ch211-222e23.2	0.016
zgc:56136	zgc:56136	0.016
rdh5	retinol dehydrogenase 5 (11-cis/9-cis)	0.015
msi1	musashi homolog 1 (Drosophila)	0.015
nr5a2	nuclear receptor subfamily 5, group A, member 2	0.015
pttg1ipb	pituitary tumor-transforming 1 interacting protein b	0.015
gnrh3	gonadotropin-releasing hormone 3	0.015
cx41.8	connexin 41.8	0.015
st8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.015
cx32.3	connexin 32.3	0.014
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.014
fhl2b	four and a half LIM domains 2b	0.014
stmn4	stathmin-like 4	0.014
fgf19	fibroblast growth factor 19	0.014
cadm1b	cell adhesion molecule 1b	0.014
impdh1b	inosine 5'-phosphate dehydrogenase 1b	0.014
hbae3	hemoglobin alpha embryonic-3	0.014
gfra1b	gdnf family receptor alpha 1b	0.014
aldh6a1	aldehyde dehydrogenase 6 family, member A1	0.014
optc	opticin	0.014
rag1	recombination activating gene 1	0.013
pck2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	0.013
LOC570775	protein argonaute-1-like	0.013
hgd	homogentisate 1,2-dioxygenase	0.013
chrna6	cholinergic receptor, nicotinic, alpha 6	0.013
zgc:56231	zgc:56231	0.013
si:dkeyp-94b4.2	si:dkeyp-94b4.2	0.013
tbx5a	T-box 5a	0.013
cadm1a	cell adhesion molecule 1a	0.013
ucp1	uncoupling protein 1	0.013
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.013
pcdh17	protocadherin 17	0.012
si:ch211-209p5.2	si:ch211-209p5.2	0.012
rpe65a	retinal pigment epithelium-specific protein 65a	0.012
slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.012
mao	monoamine oxidase	0.012
erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog	0.012
phex	phosphate regulating gene with homologues to endopeptidases on the X chromosome	0.012
kal1a	Kallmann syndrome 1a sequence	0.011
kcnj13	potassium inwardly-rectifying channel, subfamily J, member 13	0.011
gpr182	G protein-coupled receptor 182	0.011
pmch	pro-melanin concentrating hormone	0.011
mest	mesoderm specific transcript	0.011
cpa2	carboxypeptidase A2 (pancreatic)	0.011
mmp13a	matrix metalloproteinase 13a	0.011
zgc:66484	zgc:66484	0.011
nfe2l1	nuclear factor, erythroid derived 2,-like 1	0.011
itgb3b	integrin beta 3b	0.011
prl	prolactin	0.011
dlg1	discs, large (Drosophila) homolog 1	0.011
mdh1a	malate dehydrogenase 1a, NAD (soluble)	0.011
flt4	fms-related tyrosine kinase 4	0.011
aldh7a1	aldehyde dehydrogenase 7 family, member A1	0.011
isoc2	isochorismatase domain containing 2	0.011
xgb	x globin	0.011
esr2b	estrogen receptor 2b	0.011
pcna	proliferating cell nuclear antigen	0.011
tac1	tachykinin 1	0.010
pax9	paired box gene 9	0.010
im:6903943	im:6903943	0.010
slc24a5	solute carrier family 24, member 5	0.010
cnr1	cannabinoid receptor 1	0.010
bmp16	bone morphogenetic protein 16	0.010
dync2i1	dynein, cytoplasmic 2, intermediate chain 1	0.010
spra	sepiapterin reductase a	0.010
zgc:56466	zgc:56466	0.010
emx2	empty spiracles homeobox 2	0.010
fah	fumarylacetoacetate hydrolase (fumarylacetoacetase)	0.010
acadl	acyl-Coenzyme A dehydrogenase, long chain	0.010
hbbe2	hemoglobin beta embryonic-2	0.010