The network for 'positive regulation of leukocyte migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of leukocyte migration

Any process that activates or increases the frequency, rate, or extent of leukocyte migration.

Homo sapiens
Name Description Probability Func Analog Organism
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.970
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.967
CCR5 chemokine (C-C motif) receptor 5 0.950
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.928
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.927
CCL5 chemokine (C-C motif) ligand 5 0.926
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.895
IL8 interleukin 8 0.883
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.837
CXCL9 chemokine (C-X-C motif) ligand 9 0.833
S100A6 S100 calcium binding protein A6 0.821
CXCL3 chemokine (C-X-C motif) ligand 3 0.796
VEGFA vascular endothelial growth factor A 0.787
CCL4 chemokine (C-C motif) ligand 4 0.782
IL1B interleukin 1, beta 0.763
FYN FYN oncogene related to SRC, FGR, YES 0.730
PLAUR plasminogen activator, urokinase receptor 0.722
CCL8 chemokine (C-C motif) ligand 8 0.715
CXCL10 chemokine (C-X-C motif) ligand 10 0.703
CXCL2 chemokine (C-X-C motif) ligand 2 0.682
DPP4 dipeptidyl-peptidase 4 0.654
S100B S100 calcium binding protein B 0.647
S100A14 S100 calcium binding protein A14 0.639
CCL7 chemokine (C-C motif) ligand 7 0.617
FAS Fas (TNF receptor superfamily, member 6) 0.614
AXL AXL receptor tyrosine kinase 0.613
S100A16 S100 calcium binding protein A16 0.574
FN1 fibronectin 1 0.561
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.551
CXCL5 chemokine (C-X-C motif) ligand 5 0.544
IL6 interleukin 6 (interferon, beta 2) 0.537
CCL2 chemokine (C-C motif) ligand 2 0.525
S100A1 S100 calcium binding protein A1 0.480
CCL22 chemokine (C-C motif) ligand 22 0.462
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.462
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.449
IFNG interferon, gamma 0.448
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.444
CCR7 chemokine (C-C motif) receptor 7 0.433
NRP1 neuropilin 1 0.427
CCL20 chemokine (C-C motif) ligand 20 0.418
TIMP1 TIMP metallopeptidase inhibitor 1 0.405
CXCL11 chemokine (C-X-C motif) ligand 11 0.389
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.375
S100A4 S100 calcium binding protein A4 0.371
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.365
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.359
TLR2 toll-like receptor 2 0.355
IL10 interleukin 10 0.334
CCL13 chemokine (C-C motif) ligand 13 0.325
CCL19 chemokine (C-C motif) ligand 19 0.314
VCAM1 vascular cell adhesion molecule 1 0.310
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.307
CCR1 chemokine (C-C motif) receptor 1 0.297
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.291
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.288
ABI2 abl-interactor 2 0.279
PDIA3 protein disulfide isomerase family A, member 3 0.277
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.275
TRAF1 TNF receptor-associated factor 1 0.267
FLNA filamin A, alpha 0.260
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.246
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.246
S100A12 S100 calcium binding protein A12 0.242
EZR ezrin 0.236
CXCL13 chemokine (C-X-C motif) ligand 13 0.228
PLAU plasminogen activator, urokinase 0.227
ITGAV integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) 0.226
PLEK pleckstrin 0.225
TNF tumor necrosis factor 0.217
CCR4 chemokine (C-C motif) receptor 4 0.216
SELE selectin E 0.215
FASLG Fas ligand (TNF superfamily, member 6) 0.208
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.198
ENG endoglin 0.197
CCL3 chemokine (C-C motif) ligand 3 0.196
COL4A1 collagen, type IV, alpha 1 0.195
MEFV Mediterranean fever 0.187
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.187
COL1A1 collagen, type I, alpha 1 0.173
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.171
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.170
IL2RB interleukin 2 receptor, beta 0.165
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.162
AQP9 aquaporin 9 0.157
S100A9 S100 calcium binding protein A9 0.151
PTPRC protein tyrosine phosphatase, receptor type, C 0.150
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.149
PI3 peptidase inhibitor 3, skin-derived 0.140
TGIF1 TGFB-induced factor homeobox 1 0.140
CD2 CD2 molecule 0.125
IL1R2 interleukin 1 receptor, type II 0.123
TLN1 talin 1 0.120
PLAT plasminogen activator, tissue 0.118
CXCR4 chemokine (C-X-C motif) receptor 4 0.118
MICA MHC class I polypeptide-related sequence A 0.118
IRF4 interferon regulatory factor 4 0.114
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.114
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.113
DLG1 discs, large homolog 1 (Drosophila) 0.107
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
cdh5 cadherin 5 0.498
etv2 ets variant gene 2 0.408
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.351
kdrl kinase insert domain receptor like 0.310
sox7 SRY-box containing gene 7 0.261
tie1 endothelium-specific receptor tyrosine kinase 1 0.255
si:ch211-235f6.2 si:ch211-235f6.2 0.161
postn periostin, osteoblast specific factor 0.148
erg v-ets erythroblastosis virus E26 oncogene like (avian) 0.138
osr1 odd-skipped related 1 (Drosophila) 0.137
fli1a friend leukemia integration 1a 0.118
tie2 endothelium-specific receptor tyrosine kinase 2 0.109
si:ch211-212m21.5 si:ch211-212m21.5 0.099
calcrla calcitonin receptor-like a 0.097
mmp2 matrix metalloproteinase 2 0.089
cbfb core-binding factor, beta subunit 0.065
plxnd1 plexin D1 0.064
foxc1a forkhead box C1a 0.059
hnf1a HNF1 homeobox a 0.059
dll4 delta-like 4 (Drosophila) 0.058
si:dkey-261h17.1 si:dkey-261h17.1 0.056
cdc42 cell division cycle 42 0.054
agtr2 angiotensin II receptor, type 2 0.053
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.050
nphs1l nephrosis 1, congenital, Finnish type (nephrin)-like 0.049
esama endothelial cell adhesion molecule a 0.048
efnb2a ephrin B2a 0.047
yrk Yes-related kinase 0.044
sema3d semaphorin 3d 0.043
zgc:195154 zgc:195154 0.042
im:7154036 im:7154036 0.041
gpr182 G protein-coupled receptor 182 0.039
hbbe1.1 hemoglobin beta embryonic-1.1 0.037
epas1b endothelial PAS domain protein 1b 0.037
col5a1 procollagen, type V, alpha 1 0.037
cxcl12a chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) 0.036
mcamb melanoma cell adhesion molecule b 0.035
rarga retinoic acid receptor gamma a 0.033
lyz lysozyme 0.032
fn1 fibronectin 1 0.032
lum lumican 0.031
hspg2 heparan sulfate proteoglycan 2 0.030
cntn2 contactin 2 0.030
vegfaa vascular endothelial growth factor Aa 0.030
ltk leukocyte tyrosine kinase 0.030
sc:d812 sc:d812 0.030
sfrp2 secreted frizzled-related protein 2 0.029
col5a2l collagen, type V, alpha 2-like 0.029
mgp matrix Gla protein 0.028
bmper BMP binding endothelial regulator 0.028
foxc1b forkhead box C1b 0.027
cdc42l cell division cycle 42, like 0.027
twist1a twist1a 0.025
fras1 Fraser syndrome 1 0.025
emilin1a elastin microfibril interfacer 1a 0.025
f2r coagulation factor II (thrombin) receptor 0.025
ccbe1 collagen and calcium binding EGF domains 1 0.025
ncf1 neutrophil cytosolic factor 1 0.024
bnc2 basonuclin 2 0.024
cysltr1 cysteinyl leukotriene receptor 1 0.024
col12a1 collagen, type XII, alpha 1 0.024
myod1 myogenic differentiation 1 0.023
efemp2 EGF-containing fibulin-like extracellular matrix protein 2 0.023
atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide 0.023
sfrp1b secreted frizzled-related protein 1b 0.023
thy1 Thy-1 cell surface antigen 0.022
lta4h leukotriene A4 hydrolase 0.022
nrp2a neuropilin 2a 0.022
podxl podocalyxin-like 0.021
ccl25b chemokine (C-C motif) ligand 25b 0.021
kcnj13 potassium inwardly-rectifying channel, subfamily J, member 13 0.021
ippk inositol 1,3,4,5,6-pentakisphosphate 2-kinase 0.021
ntn4 netrin 4 0.021
jag1a jagged 1a 0.021
emp2 epithelial membrane protein 2 0.021
cyt1 type I cytokeratin, enveloping layer 0.020
masp2 mannan-binding lectin serine peptidase 2 0.020
mmp17a matrix metallopeptidase 17a 0.020
mmp13a matrix metalloproteinase 13a 0.019
twist2 twist2 0.019
aplnrb apelin receptor b 0.019
zgc:172284 zgc:172284 0.019
notch2 notch homolog 2 0.019
hspa12b heat shock protein 12B 0.019
vegfc vascular endothelial growth factor c 0.019
appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.019
stab2 stabilin 2 0.019
rhogb ras homolog gene family, member Gb 0.019
ptprsa protein tyrosine phosphatase, receptor type, s, a 0.019
wu:fj39b01 wu:fj39b01 0.019
adora2b adenosine A2b receptor 0.019
wu:fv91b12 wu:fv91b12 0.018
si:dkeyp-110g5.2 si:dkeyp-110g5.2 0.018
pmela premelanosome protein a 0.018
ca15a carbonic anhydrase XV a 0.018
tlr18 toll-like receptor 18 0.018
nrp1a neuropilin 1a 0.018
cd248a CD248 molecule, endosialin a 0.018
clec14a C-type lectin domain family 14, member A 0.017
itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.017
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ccl2 chemokine (C-C motif) ligand 2 0.895
Ccl4 chemokine (C-C motif) ligand 4 0.767
Cxcl10 chemokine (C-X-C motif) ligand 10 0.750
Il1b interleukin 1 beta 0.746
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.735
Cxcl2 chemokine (C-X-C motif) ligand 2 0.652
Il8rb interleukin 8 receptor, beta 0.623
Socs3 suppressor of cytokine signaling 3 0.582
Olr1500 olfactory receptor 1500 0.568
Cd4 Cd4 molecule 0.541
Il1a interleukin 1 alpha 0.496
Ccl3 chemokine (C-C motif) ligand 3 0.487
Hck hemopoietic cell kinase 0.404
Cd14 CD14 molecule 0.371
Il6 interleukin 6 0.364
Ccl7 chemokine (C-C motif) ligand 7 0.352
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.352
Thbd thrombomodulin 0.340
Mmp3 matrix metallopeptidase 3 0.335
Cybb cytochrome b-245, beta polypeptide 0.276
Icam1 intercellular adhesion molecule 1 0.270
Calcrl calcitonin receptor-like 0.237
Lamc1 laminin, gamma 1 0.234
Plau plasminogen activator, urokinase 0.231
Ccbp2 chemokine binding protein 2 0.224
Fosl1 fos-like antigen 1 0.221
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.190
Neurl3 neuralized homolog 3 (Drosophila) 0.178
Ednra endothelin receptor type A 0.161
Fgf2 fibroblast growth factor 2 0.155
Aqp8 aquaporin 8 0.154
Myl7 myosin, light chain 7, regulatory 0.147
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.146
RT1-Db1 RT1 class II, locus Db1 0.146
F2rl2 coagulation factor II (thrombin) receptor-like 2 0.145
Zbp1 Z-DNA binding protein 1 0.143
Mamdc4 MAM domain containing 4 0.143
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.140
Ccr5 chemokine (C-C motif) receptor 5 0.136
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.128
Mrgprf MAS-related GPR, member F 0.127
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.126
Reg3g regenerating islet-derived 3 gamma 0.124
Mmp10 matrix metallopeptidase 10 0.123
Kcna3 potassium voltage-gated channel, shaker-related subfamily, member 3 0.118
Ccr2 chemokine (C-C motif) receptor 2 0.114
Htr5b 5-hydroxytryptamine (serotonin) receptor 5B 0.111
Il2rb interleukin 2 receptor, beta 0.110
Hpgds hematopoietic prostaglandin D synthase 0.108
Csf1 colony stimulating factor 1 (macrophage) 0.105
RT1-Bb RT1 class II, locus Bb 0.103
Igsf6 immunoglobulin superfamily, member 6 0.102
Cd86 CD86 molecule 0.099
P2ry14 purinergic receptor P2Y, G-protein coupled, 14 0.098
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.098
Timp1 TIMP metallopeptidase inhibitor 1 0.098
Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 0.098
Psp parotid secretory protein 0.095
Olfml2b olfactomedin-like 2B 0.094
Il1rn interleukin 1 receptor antagonist 0.093
Ctsj cathepsin J 0.092
Olr1078 olfactory receptor 1078 0.092
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.087
Gzmk granzyme K 0.086
Ccl20 chemokine (C-C motif) ligand 20 0.084
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.081
Vip vasoactive intestinal peptide 0.079
Prkcg protein kinase C, gamma 0.079
Fcn1 ficolin (collagen/fibrinogen domain containing) 1 0.079
RGD1561143 similar to cell surface receptor FDFACT 0.079
LOC100360403 ATP-binding cassette, sub-family C, member 9-like 0.076
Ptafr platelet-activating factor receptor 0.072
RT1-Ba RT1 class II, locus Ba 0.070
Ngf nerve growth factor (beta polypeptide) 0.068
Il1r2 interleukin 1 receptor, type II 0.064
Atxn1 ataxin 1 0.064
Tyrobp Tyro protein tyrosine kinase binding protein 0.062
Sell selectin L 0.062
Casp1 caspase 1 0.059
Ier3 immediate early response 3 0.059
Gzmb granzyme B 0.058
Edn1 endothelin 1 0.058
Ereg epiregulin 0.057
Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 0.057
Napsa napsin A aspartic peptidase 0.055
Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.054
Htr2b 5-hydroxytryptamine (serotonin) receptor 2B 0.054
Efnb1 ephrin B1 0.052
Cd5 Cd5 molecule 0.051
Col12a1 collagen, type XII, alpha 1 0.051
Il12b interleukin 12B 0.051
Tgfbr2 transforming growth factor, beta receptor II 0.050
Dnase1l3 deoxyribonuclease 1-like 3 0.050
Tgfbr3 transforming growth factor, beta receptor III 0.050
Faslg Fas ligand (TNF superfamily, member 6) 0.049
Ucn urocortin 0.047
C5ar1 complement component 5a receptor 1 0.047
Mmp12 matrix metallopeptidase 12 0.047
Cga glycoprotein hormones, alpha polypeptide 0.046
Trh thyrotropin releasing hormone 0.044
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism