The network for 'multicellular organismal reproductive process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

multicellular organismal reproductive process

The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.

Name Description Probability Func Analog Organism
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.940
ESR1 estrogen receptor 1 0.914
CREBBP CREB binding protein 0.739
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.713
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.595
RB1 retinoblastoma 1 0.580
QKI quaking homolog, KH domain RNA binding (mouse) 0.530
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.523
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.522
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.507
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.462
UBC ubiquitin C 0.451
EP300 E1A binding protein p300 0.444
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.422
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.422
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.416
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.414
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.409
SMAD2 SMAD family member 2 0.393
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.389
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.355
TP53 tumor protein p53 0.340
SP1 Sp1 transcription factor 0.330
ATXN1 ataxin 1 0.325
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.322
CSNK2B casein kinase 2, beta polypeptide 0.320
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.315
EGFR epidermal growth factor receptor 0.294
SNRPF small nuclear ribonucleoprotein polypeptide F 0.289
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.277
ATF2 activating transcription factor 2 0.266
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.251
APC adenomatous polyposis coli 0.244
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.232
ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.232
TCP1 t-complex 1 0.226
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.223
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.222
SSB Sjogren syndrome antigen B (autoantigen La) 0.209
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.206
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.198
CDK2 cyclin-dependent kinase 2 0.195
RBM39 RNA binding motif protein 39 0.195
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.191
CCT7 chaperonin containing TCP1, subunit 7 (eta) 0.180
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.178
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.162
MTA1 metastasis associated 1 0.161
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.161
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 0.160
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.152
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.151
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.149
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.149
BRCA1 breast cancer 1, early onset 0.148
CAND1 cullin-associated and neddylation-dissociated 1 0.146
CUL2 cullin 2 0.137
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.136
EIF3H eukaryotic translation initiation factor 3, subunit H 0.135
NCOR2 nuclear receptor corepressor 2 0.134
CUL3 cullin 3 0.134
RHOA ras homolog gene family, member A 0.133
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.129
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.129
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.126
FLNA filamin A, alpha 0.121
CDC5L CDC5 cell division cycle 5-like (S. pombe) 0.121
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.118
SMAD3 SMAD family member 3 0.113
SRPK2 SRSF protein kinase 2 0.113
SEPT2 septin 2 0.112
SRSF1 serine/arginine-rich splicing factor 1 0.112
JAK2 Janus kinase 2 0.110
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.110
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.106
PABPC1 poly(A) binding protein, cytoplasmic 1 0.103
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.101
GRB10 growth factor receptor-bound protein 10 0.101
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.100
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.099
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.098
SMAD1 SMAD family member 1 0.097
LRRK2 leucine-rich repeat kinase 2 0.095
NCL nucleolin 0.095
EIF3A eukaryotic translation initiation factor 3, subunit A 0.094
CAV1 caveolin 1, caveolae protein, 22kDa 0.094
EIF3E eukaryotic translation initiation factor 3, subunit E 0.093
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.093
HMGA1 high mobility group AT-hook 1 0.092
RANBP2 RAN binding protein 2 0.090
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.089
CUL1 cullin 1 0.089
CREB1 cAMP responsive element binding protein 1 0.086
RBM10 RNA binding motif protein 10 0.086
SNRPE small nuclear ribonucleoprotein polypeptide E 0.085
GSK3B glycogen synthase kinase 3 beta 0.083
BRCA2 breast cancer 2, early onset 0.083
SKP2 S-phase kinase-associated protein 2 (p45) 0.083
INSR insulin receptor 0.082
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.081
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.983
pha-4 Protein PHA-4 0.972
hlh-2 Protein HLH-2 0.948
npp-1 Protein NPP-1 0.944
par-5 Protein PAR-5 0.940
vab-3 Protein VAB-3 0.932
egl-13 Protein EGL-13 0.930
mat-3 Protein MAT-3 0.907
lag-1 Protein LAG-1 0.904
ruvb-1 Protein RUVB-1 0.901
his-48 Protein HIS-48 0.888
cgh-1 Protein CGH-1 0.888
unc-53 Protein UNC-53 0.881
sma-6 Protein SMA-6 0.879
egl-30 Protein EGL-30 0.872
prp-8 Protein PRP-8 0.870
lin-29 Protein LIN-29 0.860
gex-3 Protein GEX-3 0.860
gpr-1 Protein GPR-1 0.859
rpl-3 Protein RPL-3 0.859
gld-1 Protein GLD-1 0.857
wrm-1 Protein WRM-1 0.854
egl-15 Protein EGL-15 0.847
his-47 Protein HIS-47 0.843
ceh-20 Protein CEH-20 0.841
unc-54 Protein UNC-54 0.837
sem-5 Protein SEM-5 0.837
taf-5 Protein TAF-5 0.832
goa-1 Protein GOA-1 0.831
his-5 Protein HIS-5 0.827
cbd-1 Protein CBD-1 0.826
CELE_C12D8.1 Protein C12D8.1 0.825
icd-1 Protein ICD-1 0.823
cye-1 Protein CYE-1 0.821
CELE_C16C10.4 Protein C16C10.4 0.821
rpa-1 Protein RPA-1 0.818
hpo-32 Protein HPO-32 0.815
his-62 Protein HIS-62 0.812
vha-8 Protein VHA-8 0.808
dao-5 Protein DAO-5 0.806
lec-1 Protein LEC-1 0.801
rol-6 Protein ROL-6 0.800
his-61 Protein HIS-61 0.796
gls-1 Protein GLS-1 0.795
hsp-1 Protein HSP-1 0.795
egg-1 Protein EGG-1 0.784
rpt-5 Protein RPT-5 0.784
rpa-2 Protein RPA-2 0.782
lin-53 Protein LIN-53 0.781
cdc-37 Protein CDC-37 0.775
mom-2 Protein MOM-2 0.768
tag-232 Protein TAG-232 0.760
scc-1 Protein SCC-1 0.757
eef-1A.1 Protein EEF-1A.1 0.753
cks-1 Protein CKS-1 0.750
unc-37 Protein UNC-37 0.747
mcm-2 Protein MCM-2 0.747
his-16 Protein HIS-16 0.743
ppp-1 Protein PPP-1 0.742
mex-6 Protein MEX-6 0.740
sma-3 Protein SMA-3 0.737
let-502 Protein LET-502 0.736
snr-4 Protein SNR-4 0.735
egl-36 Protein EGL-36 0.734
his-45 Protein HIS-45 0.732
rpl-7A Protein RPL-7A 0.731
pdfr-1 Protein PDFR-1 0.724
egg-6 Protein EGG-6 0.717
hda-1 Protein HDA-1 0.717
csn-5 Protein CSN-5 0.713
pos-1 Protein POS-1 0.713
his-64 Protein HIS-64 0.708
unc-60 Protein UNC-60 0.708
his-1 Protein HIS-1 0.707
let-716 Protein LET-716 0.703
ptc-1 Protein PTC-1 0.702
swsn-1 Protein SWSN-1 0.700
CELE_W02F12.3 Protein W02F12.3 0.698
nap-1 Protein NAP-1 0.697
fem-3 Protein FEM-3 0.696
his-68 Protein HIS-68 0.696
eif-6 Protein EIF-6 0.695
snr-6 Protein SNR-6 0.694
tba-1 Protein TBA-1 0.694
unc-9 Protein UNC-9 0.693
cir-1 Protein CIR-1 0.693
dre-1 Protein DRE-1 0.692
his-46 Protein HIS-46 0.684
zip-7 Protein ZIP-7 0.684
snr-1 Protein SNR-1 0.683
cin-4 Protein CIN-4 0.682
inx-5 Protein INX-5 0.682
nhr-67 Protein NHR-67 0.679
ztf-7 Protein ZTF-7 0.676
sel-9 Protein SEL-9 0.674
rsp-1 Protein RSP-1 0.673
T09B4.1 Protein T09B4.1 0.672
zif-1 Protein ZIF-1 0.672
tag-170 Protein TAG-170 0.670
unc-36 Protein UNC-36 0.668
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Danio rerio
Name Description Probability Func Analog Organism
prdm1a PR domain containing 1a, with ZNF domain 0.993
piwil1 piwi-like 1 (Drosophila) 0.947
gli1 GLI-Kruppel family member 1 0.828
sox9a SRY-box containing gene 9a 0.810
nanos3 nanos homolog 3 0.783
ptch2 patched 2 0.765
smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.706
myhz1.1 myosin, heavy polypeptide 1.1, skeletal muscle 0.663
pax2a paired box gene 2a 0.640
fancl Fanconi anemia, complementation group L 0.626
lamc1 laminin, gamma 1 0.625
bmp2b bone morphogenetic protein 2b 0.572
e2f5 E2F transcription factor 5 0.527
axin1 axin 1 0.483
ptch1 patched 1 0.470
dlc deltaC 0.462
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.424
gpr126 G protein-coupled receptor 126 0.408
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.404
gro1 groucho 1 0.387
pbx4 pre-B-cell leukemia transcription factor 4 0.360
tll1 tolloid-like 1 0.355
hhip hedgehog interacting protein 0.352
elk4 ELK4, ETS-domain protein 0.348
khdrbs1a KH domain containing, RNA binding, signal transduction associated 1a 0.346
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.339
tfap2a transcription factor AP-2 alpha 0.334
cyp19a1a cytochrome P450, family 19, subfamily A, polypeptide 1a 0.321
nkx2.2a NK2 transcription factor related 2a 0.321
dharma dharma 0.318
efnb2a ephrin B2a 0.313
gli2b GLI-Kruppel family member GLI2b 0.310
hsp90b1 heat shock protein 90, beta (grp94), member 1 0.296
musk muscle, skeletal, receptor tyrosine kinase 0.296
ccnb1 cyclin B1 0.295
robo3 roundabout homolog 3 0.279
eif4a3 eukaryotic translation initiation factor 4A, isoform 3 0.275
cxcr4b chemokine (C-X-C motif), receptor 4b 0.264
srf serum response factor 0.263
lhx1a LIM homeobox 1a 0.262
prickle1a prickle-like 1 (Drosophila) a 0.257
sox11b SRY-box containing gene 11b 0.253
sema3aa semaphorin 3aa 0.251
alcamb activated leukocyte cell adhesion molecule b 0.250
sox19a SRY-box containing gene 19a 0.249
wnt9a wingless-type MMTV integration site family, member 9A 0.245
cc2d2a coiled-coil and C2 domain containing 2A 0.242
brca2 breast cancer 2, early onset 0.236
mef2d myocyte enhancer factor 2d 0.230
pax7a paired box gene 7a 0.227
smyhc2 slow myosin heavy chain 2 0.225
cdc26 cell division cycle 26 homolog 0.212
uxs1 UDP-glucuronic acid decarboxylase 1 0.210
ihha Indian hedgehog homolog a 0.203
cyp11a1 cytochrome P450, subfamily XIA, polypeptide 1 0.203
per3 period homolog 3 (Drosophila) 0.203
tbpl2 TATA box binding protein like 2 0.202
dmrt3a doublesex and mab-3 related transcription factor 3a 0.195
actn2 actinin, alpha 2 0.193
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.192
egr1 early growth response 1 0.192
eng2a engrailed 2a 0.189
crabp2a cellular retinoic acid binding protein 2, a 0.189
neurod neurogenic differentiation 0.185
gata5 GATA-binding protein 5 0.184
gng3 guanine nucleotide binding protein (G protein), gamma 3 0.183
pdip5 protein disulfide isomerase-related protein (provisional) 0.183
paqr8 progestin and adipoQ receptor family member VIII 0.177
odc1 ornithine decarboxylase 1 0.176
zic3 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) 0.176
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.172
tagln2 transgelin 2 0.171
ntla no tail a 0.171
sox5 SRY-box containing gene 5 0.169
brd4 bromodomain containing 4 0.167
mycbp2 MYC binding protein 2 0.167
rag1 recombination activating gene 1 0.165
myf5 myogenic factor 5 0.165
sycp3l synaptonemal complex protein 3 like 0.164
chd chordin 0.161
bdnf brain-derived neurotrophic factor 0.159
myod1 myogenic differentiation 1 0.157
twist1a twist1a 0.156
hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.154
prp19 PRP19/PSO4 homolog (S. cerevisiae) 0.154
pcdh8 protocadherin 8 0.152
dhrs3a dehydrogenase/reductase (SDR family) member 3a 0.149
ass1 argininosuccinate synthetase 1 0.146
plcg1 phospholipase C, gamma 1 0.146
clock clock 0.145
snai1b snail homolog 1b (Drosophila) 0.145
actn3a actinin alpha 3a 0.145
etv5b ets variant 5b 0.142
tdrd1 tudor domain containing 1 0.142
foxo3b forkhead box O3b 0.141
her7 hairy and enhancer of split related-7 0.139
egr2b early growth response 2b 0.138
sox32 SRY-box containing gene 32 0.136
six1b sine oculis homeobox homolog 1b 0.134
lama4 laminin, alpha 4 0.134
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Trhr2 thyrotropin releasing hormone receptor 2 0.428
Gip gastric inhibitory polypeptide 0.372
Slc13a2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 0.289
Grin3a glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.263
Agtr2 angiotensin II receptor, type 2 0.255
Nefl neurofilament, light polypeptide 0.252
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.251
Scnn1g sodium channel, nonvoltage-gated 1, gamma 0.247
Trhr thyrotropin releasing hormone receptor 0.237
Mapk3 mitogen activated protein kinase 3 0.237
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.235
Pip prolactin induced protein 0.233
Ednrb endothelin receptor type B 0.225
Olr1078 olfactory receptor 1078 0.222
Canx calnexin 0.216
Ina internexin neuronal intermediate filament protein, alpha 0.215
Bcl2 B-cell CLL/lymphoma 2 0.214
Rorb RAR-related orphan receptor B 0.213
Snap25 synaptosomal-associated protein 25 0.209
Pfn1 profilin 1 0.198
Arf4 ADP-ribosylation factor 4 0.198
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.197
Plaur plasminogen activator, urokinase receptor 0.192
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.192
Oprl1 opiate receptor-like 1 0.188
Fth1 ferritin, heavy polypeptide 1 0.187
Rhoj ras homolog gene family, member J 0.179
Cdk2 cyclin dependent kinase 2 0.179
Ugt2b7 UDP glucuronosyltransferase 2 family, polypeptide B7 0.179
Cp ceruloplasmin 0.177
Itgb1 integrin, beta 1 0.175
Hcrtr1 hypocretin (orexin) receptor 1 0.173
Hcrtr2 hypocretin (orexin) receptor 2 0.170
Atxn3 ataxin 3 0.169
Cgm4 carcinoembryonic antigen gene family 4 0.166
Ccr1 chemokine (C-C motif) receptor 1 0.163
Ifitm3 interferon induced transmembrane protein 3 0.163
Pou2f3 POU class 2 homeobox 3 0.162
Tmpo thymopoietin 0.161
Adam17 ADAM metallopeptidase domain 17 0.161
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.160
Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 0.160
Nfia nuclear factor I/A 0.159
Eef2 eukaryotic translation elongation factor 2 0.159
Flt1 FMS-related tyrosine kinase 1 0.159
Actb actin, beta 0.159
Prpg1 proline-rich proteoglycan 1 0.158
Mak male germ cell-associated kinase 0.157
Fn1 fibronectin 1 0.155
Myh9 myosin, heavy chain 9, non-muscle 0.154
Bmpr1a bone morphogenetic protein receptor, type IA 0.154
Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.153
Il12b interleukin 12B 0.153
Cd14 CD14 molecule 0.153
Prl prolactin 0.152
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.148
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.148
Gabra5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 0.148
Efna5 ephrin A5 0.148
Akr1c18 aldo-keto reductase family 1, member C18 0.147
Cela2a chymotrypsin-like elastase family, member 2A 0.146
Gabra1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.146
Csn1s2a casein alpha s2-like A 0.145
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.144
LOC246267 resection-induced TPI (rs11) 0.143
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.141
Ptgs2 prostaglandin-endoperoxide synthase 2 0.140
Sycn syncollin 0.139
Utrn utrophin 0.138
Prl4a1 prolactin family 4, subfamily a, member 1 0.137
Smad3 SMAD family member 3 0.135
Lman1 lectin, mannose-binding, 1 0.135
Elavl4 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) 0.135
Cnbp CCHC-type zinc finger, nucleic acid binding protein 0.135
Tcof1 Treacher Collins-Franceschetti syndrome 1 homolog (human) 0.134
Slc16a8 solute carrier family 16, member 8 (monocarboxylic acid transporter 3) 0.133
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.133
Ptprc protein tyrosine phosphatase, receptor type, C 0.133
Olr1493 olfactory receptor gene Olr1493 0.133
Chrna2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 0.132
Cd44 Cd44 molecule 0.132
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.131
Cga glycoprotein hormones, alpha polypeptide 0.130
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.130
Efnb1 ephrin B1 0.130
Pebp1 phosphatidylethanolamine binding protein 1 0.129
Htr6 5-hydroxytryptamine (serotonin) receptor 6 0.127
Prkch protein kinase C, eta 0.127
Igfbp5 insulin-like growth factor binding protein 5 0.127
Gpx4 glutathione peroxidase 4 0.127
Smad7 SMAD family member 7 0.126
Drd3 dopamine receptor D3 0.126
Il1rn interleukin 1 receptor antagonist 0.124
Scnn1b sodium channel, nonvoltage-gated 1, beta 0.124
Anxa4 annexin A4 0.123
Cd80 Cd80 molecule 0.123
Add2 adducin 2 (beta) 0.123
Syt4 synaptotagmin IV 0.123
Irs1 insulin receptor substrate 1 0.122
Calu calumenin 0.122
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism