The network for 'guanosine containing compound metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

guanosine containing compound metabolic process

The chemical reactions and pathways involving guanosine-containing compounds (guanosines).

Mus musculus
Name Description Probability Func Analog Organism
Epha4 Eph receptor A4 0.994
Grb2 growth factor receptor bound protein 2 0.993
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.993
Efnb2 ephrin B2 0.991
Rac1 RAS-related C3 botulinum substrate 1 0.981
Dnm1 dynamin 1 0.981
Drd2 dopamine receptor D2 0.949
Arrb2 arrestin, beta 2 0.944
Ephb2 Eph receptor B2 0.940
Kl klotho 0.938
Nf1 neurofibromatosis 1 0.937
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.931
Mtor mechanistic target of rapamycin (serine/threonine kinase) 0.927
Dlg4 discs, large homolog 4 (Drosophila) 0.915
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.908
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.902
Eea1 early endosome antigen 1 0.892
Rab5a RAB5A, member RAS oncogene family 0.884
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.881
Pxn paxillin 0.868
Plxna1 plexin A1 0.864
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.841
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.837
Stxbp3a syntaxin binding protein 3A 0.836
Bax BCL2-associated X protein 0.831
Akt1 thymoma viral proto-oncogene 1 0.820
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.817
Rab1 RAB1, member RAS oncogene family 0.814
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.813
Igtp interferon gamma induced GTPase 0.797
Tmem30a transmembrane protein 30A 0.790
Ntf3 neurotrophin 3 0.788
Plcg1 phospholipase C, gamma 1 0.786
Selplg selectin, platelet (p-selectin) ligand 0.767
Lrrk2 leucine-rich repeat kinase 2 0.738
Cbl Casitas B-lineage lymphoma 0.736
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.729
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.721
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.710
Src Rous sarcoma oncogene 0.703
Plxnb1 plexin B1 0.695
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.686
Arhgap30 Rho GTPase activating protein 30 0.673
Eef1a1 eukaryotic translation elongation factor 1 alpha 1 0.672
Mapkap1 mitogen-activated protein kinase associated protein 1 0.670
Spry2 sprouty homolog 2 (Drosophila) 0.653
Ltb lymphotoxin B 0.635
Sh3bp1 SH3-domain binding protein 1 0.631
Eps15 epidermal growth factor receptor pathway substrate 15 0.630
Uba3 ubiquitin-like modifier activating enzyme 3 0.621
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.620
Sos2 son of sevenless homolog 2 (Drosophila) 0.611
Rtkn rhotekin 0.610
Pde1b phosphodiesterase 1B, Ca2+-calmodulin dependent 0.607
Ptpn13 protein tyrosine phosphatase, non-receptor type 13 0.607
Strn3 striatin, calmodulin binding protein 3 0.603
Pik3cb phosphatidylinositol 3-kinase, catalytic, beta polypeptide 0.597
Rab11a RAB11a, member RAS oncogene family 0.592
Tgtp2 T-cell specific GTPase 2 0.587
Epb4.1l2 erythrocyte protein band 4.1-like 2 0.585
Rhob ras homolog gene family, member B 0.584
Braf Braf transforming gene 0.583
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.582
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.582
Fmnl1 formin-like 1 0.581
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.576
Dock1 dedicator of cytokinesis 1 0.566
Sox10 SRY-box containing gene 10 0.558
Hmha1 histocompatibility (minor) HA-1 0.558
Ccl2 chemokine (C-C motif) ligand 2 0.552
Serinc1 serine incorporator 1 0.551
Shc1 src homology 2 domain-containing transforming protein C1 0.537
Ret ret proto-oncogene 0.532
Gpsm3 G-protein signalling modulator 3 (AGS3-like, C. elegans) 0.527
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.500
Ly6h lymphocyte antigen 6 complex, locus H 0.498
Parva parvin, alpha 0.493
Epha1 Eph receptor A1 0.487
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.486
Bcr breakpoint cluster region 0.481
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.478
Iigp1 interferon inducible GTPase 1 0.476
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.472
Cpeb2 cytoplasmic polyadenylation element binding protein 2 0.468
Cd37 CD37 antigen 0.467
Fgfr3 fibroblast growth factor receptor 3 0.461
Klf7 Kruppel-like factor 7 (ubiquitous) 0.460
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.452
Mlf2 myeloid leukemia factor 2 0.451
Rapgef1 Rap guanine nucleotide exchange factor (GEF) 1 0.451
Ptp4a2 protein tyrosine phosphatase 4a2 0.449
Ifi47 interferon gamma inducible protein 47 0.445
Pnp2 purine-nucleoside phosphorylase 2 0.443
Arrdc1 arrestin domain containing 1 0.437
Stag2 stromal antigen 2 0.436
Ccdc64 coiled-coil domain containing 64 0.433
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.431
Plekho2 pleckstrin homology domain containing, family O member 2 0.431
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.431
Abl1 c-abl oncogene 1, non-receptor tyrosine kinase 0.429
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
goa-1 Protein GOA-1 0.993
let-60 Protein LET-60 0.719
sem-5 Protein SEM-5 0.654
sec-24.1 Protein SEC-24.1 0.470
CELE_F47G4.4 Protein F47G4.4 0.408
mig-2 Protein MIG-2 0.372
cdc-42 Protein CDC-42 0.361
snf-1 Protein SNF-1 0.284
etr-1 Protein ETR-1 0.283
rab-5 Protein RAB-5 0.274
lag-1 Protein LAG-1 0.272
T23F11.1 Protein T23F11.1 0.261
ykt-6 Protein YKT-6 0.256
gpr-2 Protein GPR-2 0.243
unc-26 Protein UNC-26 0.231
ina-1 Protein INA-1 0.227
lin-45 Protein LIN-45 0.220
ric-8 Protein RIC-8 0.220
daf-19 Protein DAF-19 0.214
unc-71 Protein UNC-71 0.210
spdl-1 Protein SPDL-1 0.195
osm-5 Protein OSM-5 0.190
csnk-1 Protein CSNK-1 0.188
abts-1 Protein ABTS-1 0.180
lst-4 Protein LST-4 0.163
gly-7 Protein GLY-7 0.154
mtm-3 Protein MTM-3 0.154
C18F10.7 Protein C18F10.7 0.151
cpn-1 Protein CPN-1 0.147
let-607 Protein LET-607 0.135
mpk-1 Protein MPK-1 0.135
T04F8.6 Protein T04F8.6 0.133
zfp-3 Protein ZFP-3 0.133
cyld-1 Protein CYLD-1 0.132
ced-10 Protein CED-10 0.127
plc-3 Protein PLC-3 0.126
dpf-3 Protein DPF-3 0.125
lin-10 Protein LIN-10 0.122
gpr-1 Protein GPR-1 0.119
C06A5.8 Protein C06A5.8 0.117
sax-3 Protein SAX-3 0.114
tat-1 Protein TAT-1 0.113
chc-1 Protein CHC-1 0.113
rsd-6 Protein RSD-6 0.112
rab-39 Protein RAB-39 0.106
Y71F9AL.17 Protein Y71F9AL.17 0.102
gei-18 Protein GEI-18 0.101
egl-30 Protein EGL-30 0.098
unc-54 Protein UNC-54 0.098
rars-2 Protein RARS-2 0.096
unc-32 Protein UNC-32 0.096
frm-3 Protein FRM-3 0.094
tpxl-1 Protein TPXL-1 0.092
gap-2 Protein GAP-2 0.089
atf-7 Protein ATF-7 0.088
ret-1 Protein RET-1 0.085
unc-79 Protein UNC-79 0.084
ptp-4 Protein PTP-4 0.084
ubr-1 Protein UBR-1 0.082
glo-4 Protein GLO-4 0.081
mrck-1 Protein MRCK-1 0.081
syp-1 Protein SYP-1 0.080
rme-1 Protein RME-1 0.079
dpm-1 Protein DPM-1 0.075
F09E5.11 Protein F09E5.11 0.075
rme-4 Protein RME-4 0.074
arx-5 Protein ARX-5 0.073
CELE_Y47G6A.18 Protein Y47G6A.18 0.073
F09A5.4 Protein F09A5.4 0.071
lmn-1 Protein LMN-1 0.071
cdk-1 Protein CDK-1 0.070
CELE_W07A8.2 Protein W07A8.2 0.070
sli-1 Protein SLI-1 0.070
rhgf-2 Protein RHGF-2 0.069
CELE_C56A3.8 Protein C56A3.8 0.069
kin-2 Protein KIN-2 0.069
kbp-3 Protein KBP-3 0.069
sma-6 Protein SMA-6 0.068
pkg-1 Protein PKG-1 0.068
eor-2 Protein EOR-2 0.067
pps-1 Protein PPS-1 0.066
egrh-1 Protein EGRH-1 0.065
zfp-1 Protein ZFP-1 0.065
CELE_Y53C10A.5 Protein Y53C10A.5 0.064
itr-1 Protein ITR-1 0.063
lin-7 Protein LIN-7 0.063
ttx-1 Protein TTX-1 0.063
rps-2 Protein RPS-2 0.063
skn-1 Protein SKN-1 0.063
unc-119 Protein UNC-119 0.063
zoo-1 Protein ZOO-1 0.062
ncs-2 Protein NCS-2 0.062
flh-2 Protein FLH-2 0.061
rab-1 Protein RAB-1 0.061
CELE_Y54E10BR.5 Protein Y54E10BR.5 0.061
erp-1 Protein ERP-1 0.060
unc-60 Protein UNC-60 0.059
CELE_Y60A3A.9 Protein Y60A3A.9 0.058
CELE_T04H1.2 Protein T04H1.2 0.058
ulp-2 Protein ULP-2 0.058
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Danio rerio
Name Description Probability Func Analog Organism
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.759
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.515
plxnb2a plexin b2a 0.481
si:ch211-232m7.1 si:ch211-232m7.1 0.461
bida BH3 interacting domain death agonist 0.413
arpc5a actin related protein 2/3 complex, subunit 5A 0.413
gsna gelsolin a 0.387
gro2 groucho 2 0.371
bcl2 B-cell leukemia/lymphoma 2 0.353
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.346
zbtb4 zinc finger and BTB domain containing 4 0.288
pak2a p21 (CDKN1A)-activated kinase 2a 0.284
rtcd1 RNA terminal phosphate cyclase domain 1 0.271
ef1a elongation factor 1-alpha 0.266
rab7 RAB7, member RAS oncogene family 0.253
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.241
lrrn1 leucine rich repeat neuronal 1 0.237
mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) 0.233
zgc:56085 zgc:56085 0.226
LOC567131 calcitonin gene-related peptide type 1 receptor-like 0.218
pvrl1b poliovirus receptor-related 1b 0.218
zgc:77517 zgc:77517 0.215
grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.204
gnat2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.204
pacsin3 protein kinase C and casein kinase substrate in neurons 3 0.197
gnao1a guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a 0.197
trpv4 transient receptor potential cation channel, subfamily V, member 4 0.196
cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.193
tpm4 tropomyosin 4 0.192
flot1 flotillin 1 0.192
arf5 ADP-ribosylation factor 5 0.192
ddx56 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 0.189
pob partial optokinetic response b 0.187
snx6 sorting nexin 6 0.174
cdkl1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 0.172
msna moesin a 0.172
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.164
gpia glucose phosphate isomerase a 0.163
card9 caspase recruitment domain family, member 9 0.162
zgc:136930 zgc:136930 0.162
trpa1b transient receptor potential cation channel, subfamily A, member 1b 0.161
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.160
nf1a neurofibromin 1a 0.160
gap43 growth associated protein 43 0.160
esyt3 extended synaptotagmin-like protein 3 0.156
gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.155
fgfr1b fibroblast growth factor receptor 1b 0.154
gnaia guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a 0.154
il11ra interleukin 11 receptor, alpha 0.152
vasp vasodilator-stimulated phosphoprotein 0.152
rhoaa ras homolog gene family, member Aa 0.152
olfm2 olfactomedin 2 0.149
zgc:92392 zgc:92392 0.147
efna1b ephrin A1b 0.146
gna14 guanine nucleotide binding protein (G protein), alpha 14 0.146
tm9sf2 transmembrane 9 superfamily member 2 0.141
acsl4a acyl-CoA synthetase long-chain family member 4a 0.140
rhoab ras homolog gene family, member Ab 0.140
stam signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.140
atp1b3a ATPase, Na+/K+ transporting, beta 3a polypeptide 0.139
mecp2 methyl CpG binding protein 2 0.137
arf2 ADP-ribosylation factor 2 0.137
ttyh2l tweety homolog 2, like 0.136
kif20bb kinesin family member 20Bb 0.136
ndel1a nudE nuclear distribution gene E homolog like 1 (A. nidulans) A 0.136
stau1 staufen, RNA binding protein, homolog 1 (Drosophila) 0.135
rargb retinoic acid receptor, gamma b 0.135
mga MAX gene associated 0.134
fmnl2a formin-like 2a 0.133
cpe carboxypeptidase E 0.133
snap25b synaptosome-associated protein 25b 0.130
dclk2 doublecortin-like kinase 2 0.130
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.130
scinlb scinderin like b 0.128
dync1h1 dynein, cytoplasmic 1, heavy chain 1 0.128
anxa13 annexin A13 0.128
nf1b neurofibromin 1b 0.127
disc1 disrupted in schizophrenia 1 0.126
zeb1 zinc finger E-box binding homeobox 1 0.126
zgc:114199 zgc:114199 0.124
zgc:91860 zgc:91860 0.124
junb jun B proto-oncogene 0.123
utp6 UTP6, small subunit (SSU) processome component, homolog (yeast) 0.123
srpr signal recognition particle receptor (docking protein) 0.122
cnn2 calponin 2 0.122
gna11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.122
sgce sarcoglycan, epsilon 0.122
ybx1 Y box binding protein 1 0.120
zgc:100942 zgc:100942 0.119
bactin2 bactin2 0.119
ivns1abpa influenza virus NS1A binding protein a 0.119
thy1 Thy-1 cell surface antigen 0.119
nxph1 neurexophilin 1 0.118
gnai2l guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like 0.118
pvrl1a poliovirus receptor-related 1a 0.118
arpc1a actin related protein 2/3 complex, subunit 1A 0.117
sept9b septin 9b 0.116
gria4b glutamate receptor, ionotropic, AMPA 4b 0.116
im:7150454 im:7150454 0.115
sox11b SRY-box containing gene 11b 0.114
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.944
Rac1 CG2248 gene product from transcript CG2248-RA 0.937
trio CG18214 gene product from transcript CG18214-RA 0.820
Rheb CG1081 gene product from transcript CG1081-RA 0.812
arm armadillo 0.709
Pten CG5671 gene product from transcript CG5671-RB 0.651
Pkn Protein kinase related to protein kinase N 0.614
drk downstream of receptor kinase 0.601
ben bendless 0.595
Rab7 Rab-protein 7 0.590
mbc myoblast city 0.583
rok Rho-kinase 0.491
Rho1 CG8416 gene product from transcript CG8416-RB 0.464
drpr draper 0.462
ttk tramtrack 0.461
Ras85D Ras oncogene at 85D 0.459
mbt mushroom bodies tiny 0.449
Tl Toll 0.446
Stat92E Signal-transducer and activator of transcription protein at 92E 0.415
Mtl Mig-2-like 0.413
Pk61C Protein kinase 61C 0.412
Abi Abelson interacting protein 0.408
cno canoe 0.398
lgs legless 0.385
baz bazooka 0.365
dm diminutive 0.359
Moe Moesin 0.357
pod1 CG4532 gene product from transcript CG4532-RF 0.352
Vps16A Vacuolar protein sorting 16A 0.347
chic chickadee 0.330
dys dysfusion 0.319
Sbf SET domain binding factor 0.313
Gyc-89Db Guanylyl cyclase at 89Db 0.300
Wnk CG7177 gene product from transcript CG7177-RA 0.295
Mad Mothers against dpp 0.273
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.254
Pak PAK-kinase 0.242
yata CG1973 gene product from transcript CG1973-RA 0.241
sqh spaghetti squash 0.233
Jra Jun-related antigen 0.231
egl egalitarian 0.231
gek genghis khan 0.229
Pak3 CG14895 gene product from transcript CG14895-RA 0.229
RpL15 Ribosomal protein L15 0.224
rl rolled 0.224
Ephrin CG1862 gene product from transcript CG1862-RA 0.223
dos daughter of sevenless 0.220
cher cheerio 0.219
G-ialpha65A G protein alphai subunit 65A 0.207
Rala Ras-related protein 0.205
NaCP60E Na channel protein 60E 0.199
RhoGAPp190 CG32555 gene product from transcript CG32555-RB 0.194
Pli Pellino 0.184
dnc dunce 0.180
plexB plexin B 0.174
Eip63E Ecdysone-induced protein 63E 0.174
CG3573 CG3573 gene product from transcript CG3573-RA 0.171
Drp1 Dynamin related protein 1 0.171
su(s) suppressor of sable 0.163
CG7158 CG7158 gene product from transcript CG7158-RA 0.161
LIMK1 LIM-kinase1 0.159
p130CAS CG1212 gene product from transcript CG1212-RA 0.157
RhoGEF2 CG9635 gene product from transcript CG9635-RF 0.156
stumps CG31317 gene product from transcript CG31317-RC 0.156
Flo-2 flotillin 2 0.151
didum dilute class unconventional myosin 0.150
Rtnl1 CG33113 gene product from transcript CG33113-RF 0.150
Tsc1 CG6147 gene product from transcript CG6147-RA 0.146
raps rapsynoid 0.144
garz gartenzwerg 0.143
mav maverick 0.142
pgant3 polypeptide GalNAc transferase 3 0.141
synj synaptojanin 0.139
Sos Son of sevenless 0.136
Khc-73 Kinesin-73 0.134
unc-104 CG8566 gene product from transcript CG8566-RB 0.131
Caki Calcium/calmodulin-dependent protein kinase 0.129
Rab14 Rab-protein 14 0.127
ninaC neither inactivation nor afterpotential C 0.124
Shc SHC-adaptor protein 0.121
CG6509 CG6509 gene product from transcript CG6509-RB 0.121
Syx7 Syntaxin 7 0.120
l(3)05822 lethal (3) 05822 0.119
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.119
mago mago nashi 0.117
Ras64B Ras oncogene at 64B 0.116
trbl tribbles 0.115
klar klarsicht 0.114
cenG1A centaurin gamma 1A 0.112
Dhc64C Dynein heavy chain 64C 0.110
EndoGI Endonuclease G inhibitor 0.109
Gyc-89Da Guanylyl cyclase at 89Da 0.108
ken ken and barbie 0.105
pbl pebble 0.103
Aats-tyr Tyrosyl-tRNA synthetase 0.101
Vps35 Vacuolar protein sorting 35 0.101
TSG101 tumor suppressor protein 101 0.100
stai stathmin 0.100
Rab11 Rab-protein 11 0.100
CG10627 CG10627 gene product from transcript CG10627-RA 0.099
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
SFN stratifin 1.000
EGFR epidermal growth factor receptor 1.000
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.999
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.999
SH3KBP1 SH3-domain kinase binding protein 1 0.998
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.995
ARRB1 arrestin, beta 1 0.993
PTK2 PTK2 protein tyrosine kinase 2 0.992
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog 0.991
S100A6 S100 calcium binding protein A6 0.989
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.989
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.989
RAB5A RAB5A, member RAS oncogene family 0.988
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.987
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.986
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.986
ITSN1 intersectin 1 (SH3 domain protein) 0.983
GRB7 growth factor receptor-bound protein 7 0.981
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.978
RHOA ras homolog gene family, member A 0.978
BBS10 Bardet-Biedl syndrome 10 0.977
SOS1 son of sevenless homolog 1 (Drosophila) 0.971
ABI1 abl-interactor 1 0.970
RAB1A RAB1A, member RAS oncogene family 0.968
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.957
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.952
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.943
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.942
GRB2 growth factor receptor-bound protein 2 0.940
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.937
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.933
NCK2 NCK adaptor protein 2 0.933
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.933
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.932
DNM1 dynamin 1 0.927
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.926
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.913
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.912
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.910
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.909
EXOSC3 exosome component 3 0.905
GDI2 GDP dissociation inhibitor 2 0.896
S100A8 S100 calcium binding protein A8 0.890
NCKAP1 NCK-associated protein 1 0.888
WDYHV1 WDYHV motif containing 1 0.887
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.882
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.874
LRRK2 leucine-rich repeat kinase 2 0.871
S100A11 S100 calcium binding protein A11 0.867
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.863
RHOG ras homolog gene family, member G (rho G) 0.860
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.859
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.857
EEA1 early endosome antigen 1 0.853
PKN3 protein kinase N3 0.851
ARL2 ADP-ribosylation factor-like 2 0.832
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.832
ILK integrin-linked kinase 0.830
ARRB2 arrestin, beta 2 0.828
VAV1 vav 1 guanine nucleotide exchange factor 0.827
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.810
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) 0.796
RABAC1 Rab acceptor 1 (prenylated) 0.786
CNKSR2 connector enhancer of kinase suppressor of Ras 2 0.780
CDK17 cyclin-dependent kinase 17 0.776
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.767
SH3BP2 SH3-domain binding protein 2 0.765
EXOSC2 exosome component 2 0.759
S100B S100 calcium binding protein B 0.753
TNK2 tyrosine kinase, non-receptor, 2 0.750
NCK1 NCK adaptor protein 1 0.748
HBXIP hepatitis B virus x interacting protein 0.744
FOS FBJ murine osteosarcoma viral oncogene homolog 0.743
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.741
UNC119 unc-119 homolog (C. elegans) 0.735
RGS2 regulator of G-protein signaling 2, 24kDa 0.734
HIPK2 homeodomain interacting protein kinase 2 0.733
CCR5 chemokine (C-C motif) receptor 5 0.728
EEF1G eukaryotic translation elongation factor 1 gamma 0.726
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.720
TRAF5 TNF receptor-associated factor 5 0.720
ZMYND11 zinc finger, MYND-type containing 11 0.712
GIMAP7 GTPase, IMAP family member 7 0.709
TSC2 tuberous sclerosis 2 0.709
RRAGA Ras-related GTP binding A 0.704
APC adenomatous polyposis coli 0.696
RHEB Ras homolog enriched in brain 0.695
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.688
TRAF1 TNF receptor-associated factor 1 0.688
S100A9 S100 calcium binding protein A9 0.679
STAT5A signal transducer and activator of transcription 5A 0.676
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.676
EXOSC10 exosome component 10 0.671
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.662
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.661
NCF2 neutrophil cytosolic factor 2 0.655
GABARAPL1 GABA(A) receptor-associated protein like 1 0.646
RAP1A RAP1A, member of RAS oncogene family 0.618
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Arl1 ADP-ribosylation factor-like 1 0.537
Pja2 praja 2, RING-H2 motif containing 0.435
Sumo1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.253
Epas1 endothelial PAS domain protein 1 0.228
Tgfbr2 transforming growth factor, beta receptor II 0.224
Amph amphiphysin 0.206
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.199
Pls3 plastin 3 (T-isoform) 0.196
Gria2 glutamate receptor, ionotropic, AMPA 2 0.176
Nckap1 NCK-associated protein 1 0.169
Jtb jumping translocation breakpoint 0.167
Gdi2 GDP dissociation inhibitor 2 0.149
Pfn1 profilin 1 0.149
Sh3gl2 SH3-domain GRB2-like 2 0.146
Pdcl phosducin-like 0.144
Rab1 RAB1, member RAS oncogene family 0.136
Sdc3 syndecan 3 0.135
Snap25 synaptosomal-associated protein 25 0.134
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.132
Arpc1b actin related protein 2/3 complex, subunit 1B 0.131
Cdk7 cyclin-dependent kinase 7 0.129
Homer1 homer homolog 1 (Drosophila) 0.125
Tek TEK tyrosine kinase, endothelial 0.125
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.124
Csk c-src tyrosine kinase 0.123
Eif4e2 eukaryotic translation initiation factor 4E family member 2 0.120
Nptn neuroplastin 0.119
Dnm1 dynamin 1 0.115
Hk1 hexokinase 1 0.113
Hr hairless 0.111
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.108
Copb2 coatomer protein complex, subunit beta 2 (beta prime) 0.104
Svop SV2 related protein 0.101
Dlg3 discs, large homolog 3 (Drosophila) 0.101
Itpr1 inositol 1,4,5-triphosphate receptor, type 1 0.100
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.098
Arpc2 actin related protein 2/3 complex, subunit 2 0.098
Lcp2 lymphocyte cytosolic protein 2 0.097
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.095
Sh2b3 SH2B adaptor protein 3 0.091
Rab5a RAB5A, member RAS oncogene family 0.089
Pum1 pumilio homolog 1 (Drosophila) 0.088
Vsnl1 visinin-like 1 0.088
Camk4 calcium/calmodulin-dependent protein kinase IV 0.087
Sh3bgrl3 SH3 domain binding glutamic acid-rich protein-like 3 0.087
Ctnnd2 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) 0.085
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.085
Mertk c-mer proto-oncogene tyrosine kinase 0.085
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.083
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.081
Psma5 proteasome (prosome, macropain) subunit, alpha type 5 0.081
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.080
Rap1b RAP1B, member of RAS oncogene family 0.080
Pdcd10 programmed cell death 10 0.080
Mbnl2 muscleblind-like 2 0.079
Scn8a sodium channel, voltage gated, type VIII, alpha subunit 0.079
Rab11a RAB11a, member RAS oncogene family 0.078
Dock9 dedicator of cytokinesis 9 0.075
Ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.074
Zfp260 zinc finger protein 260 0.074
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.073
Copb1 coatomer protein complex, subunit beta 1 0.071
Stxbp1 syntaxin binding protein 1 0.071
Sept10 septin 10 0.070
Prkch protein kinase C, eta 0.070
Cfl1 cofilin 1, non-muscle 0.070
Dbc1 deleted in bladder cancer 1 (human) 0.069
Chn1 chimerin (chimaerin) 1 0.069
Scg5 secretogranin V 0.068
Sox17 SRY (sex determining region Y)-box 17 0.067
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.067
St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 0.067
Ndrg4 N-myc downstream regulated gene 4 0.067
Sstr1 somatostatin receptor 1 0.066
Robo2 roundabout homolog 2 (Drosophila) 0.065
Adrbk1 adrenergic, beta, receptor kinase 1 0.065
RT1-DMa RT1 class II, locus DMa 0.065
Sorbs2 sorbin and SH3 domain containing 2 0.064
Stk39 serine/threonine kinase 39, STE20/SPS1 homolog (yeast) 0.064
Pi4ka phosphatidylinositol 4-kinase, catalytic, alpha 0.063
Gabra4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 0.063
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.062
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.062
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.062
Coro1a coronin, actin binding protein 1A 0.061
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.061
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.060
Cap2 CAP, adenylate cyclase-associated protein, 2 (yeast) 0.060
S1pr2 sphingosine-1-phosphate receptor 2 0.060
Ptpn18 protein tyrosine phosphatase, non-receptor type 18 0.060
Mapk3 mitogen activated protein kinase 3 0.060
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.059
Stxbp5 syntaxin binding protein 5 (tomosyn) 0.059
Itgam integrin, alpha M 0.059
Elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.059
Fkbp1a FK506 binding protein 1a 0.059
Mtpn myotrophin 0.058
Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) 0.057
Ddn dendrin 0.056
Gnb5 guanine nucleotide binding protein (G protein), beta 5 0.056
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GYL1 Gyl1p 0.643
YIP3 Yip3p 0.628
ROM2 Rom2p 0.594
RHO1 Rho1p 0.568
GDI1 Gdi1p 0.486
YPT52 Ypt52p 0.473
MKK1 Mkk1p 0.463
STE5 Ste5p 0.426
TRS65 Trs65p 0.417
VPS15 Vps15p 0.386
YPT6 Ypt6p 0.364
YPT1 Ypt1p 0.352
RAS2 Ras2p 0.333
SEC16 Sec16p 0.322
STE4 Ste4p 0.316
SPA2 Spa2p 0.286
ACK1 Ack1p 0.268
GCD6 Gcd6p 0.265
YPT53 Ypt53p 0.256
YPT10 Ypt10p 0.255
CDC42 Cdc42p 0.239
SEC24 Sec24p 0.201
KEL1 Kel1p 0.191
VPS21 Vps21p 0.175
SEC4 Sec4p 0.161
SUI3 Sui3p 0.157
YPT7 Ypt7p 0.149
FYV8 Fyv8p 0.146
NOP13 Nop13p 0.142
GCD7 Gcd7p 0.138
PEA2 Pea2p 0.137
VPS60 Vps60p 0.136
CDC25 Cdc25p 0.135
YME1 Yme1p 0.132
AKL1 Akl1p 0.131
BET3 Bet3p 0.130
SEC2 Sec2p 0.129
CDC24 Cdc24p 0.115
GIC2 Gic2p 0.113
SLM2 Slm2p 0.107
IRA1 Ira1p 0.107
SER2 Ser2p 0.103
VPH2 Vph2p 0.095
RGD1 Rgd1p 0.089
KOG1 Kog1p 0.089
TCA17 Tca17p 0.088
BEM3 Bem3p 0.088
VPS17 Vps17p 0.086
FKH1 Fkh1p 0.083
STT4 Stt4p 0.081
IOC3 Ioc3p 0.078
RAS1 Ras1p 0.076
VPS38 Vps38p 0.076
ERB1 Erb1p 0.075
FAR1 Far1p 0.074
ATG14 Atg14p 0.074
BEM2 Bem2p 0.074
PEP5 Pep5p 0.074
ATG26 Atg26p 0.072
SEC3 Sec3p 0.071
FMS1 Fms1p 0.071
YLR257W hypothetical protein 0.071
NYV1 Nyv1p 0.070
PIS1 Pis1p 0.069
FIR1 Fir1p 0.069
PPE1 Ppe1p 0.068
GPB2 Gpb2p 0.068
TRX1 Trx1p 0.067
URA4 Ura4p 0.066
BFR1 Bfr1p 0.066
SUI2 Sui2p 0.065
LSG1 Lsg1p 0.064
URA6 Ura6p 0.064
GCD1 Gcd1p 0.063
USO1 Uso1p 0.063
SED5 Sed5p 0.062
YGR012W hypothetical protein 0.061
TPM1 Tpm1p 0.061
RIM15 Rim15p 0.060
RGA1 Rga1p 0.060
BUL1 Bul1p 0.060
TOM1 Tom1p 0.059
YRB1 Yrb1p 0.059
STE20 Ste20p 0.059
AVO1 Avo1p 0.058
YNL010W hypothetical protein 0.057
YPP1 Ypp1p 0.057
BIT61 Bit61p 0.057
TRS31 Trs31p 0.056
NAT1 Nat1p 0.056
PRS2 Prs2p 0.055
RUD3 Rud3p 0.055
YIP1 Yip1p 0.055
DPH5 Dph5p 0.053
YIP4 Yip4p 0.053
APL4 Apl4p 0.053
SLM1 Slm1p 0.053
STB2 Stb2p 0.053
BUD8 Bud8p 0.051
MST1 Mst1p 0.051