The network for 'cerebellum development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cerebellum development

The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.

Mus musculus
Name Description Probability Func Analog Organism
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Gli3 GLI-Kruppel family member GLI3 1.000
Shh sonic hedgehog 0.999
Gli2 GLI-Kruppel family member GLI2 0.998
Emx1 empty spiracles homolog 1 (Drosophila) 0.998
En1 engrailed 1 0.998
Pax6 paired box gene 6 0.997
Pten phosphatase and tensin homolog 0.997
Fgfr1 fibroblast growth factor receptor 1 0.995
Lhx1 LIM homeobox protein 1 0.978
Smo smoothened homolog (Drosophila) 0.976
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.964
Pax2 paired box gene 2 0.955
Lmx1b LIM homeobox transcription factor 1 beta 0.955
Fgf8 fibroblast growth factor 8 0.954
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.953
Foxc1 forkhead box C1 0.953
Fgfr2 fibroblast growth factor receptor 2 0.940
Gbx2 gastrulation brain homeobox 2 0.933
Neurog2 neurogenin 2 0.928
Emx2 empty spiracles homolog 2 (Drosophila) 0.923
Prrx1 paired related homeobox 1 0.921
Dlx5 distal-less homeobox 5 0.915
Wnt3a wingless-related MMTV integration site 3A 0.909
Foxp2 forkhead box P2 0.891
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.890
Neurod1 neurogenic differentiation 1 0.885
Nfib nuclear factor I/B 0.882
Sox2 SRY-box containing gene 2 0.880
Chrd chordin 0.877
Dlg4 discs, large homolog 4 (Drosophila) 0.870
Ctnnb1 catenin (cadherin associated protein), beta 1 0.869
Pbx1 pre B-cell leukemia transcription factor 1 0.865
Bmp4 bone morphogenetic protein 4 0.860
Foxc2 forkhead box C2 0.851
Vangl2 vang-like 2 (van gogh, Drosophila) 0.835
Msx2 homeobox, msh-like 2 0.833
Pax3 paired box gene 3 0.829
Kiss1 KiSS-1 metastasis-suppressor 0.827
Eya1 eyes absent 1 homolog (Drosophila) 0.816
Rarg retinoic acid receptor, gamma 0.812
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.811
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.803
Phox2b paired-like homeobox 2b 0.794
Nog noggin 0.786
Pitx2 paired-like homeodomain transcription factor 2 0.781
Lhx5 LIM homeobox protein 5 0.779
Wnt6 wingless-related MMTV integration site 6 0.754
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.751
Nrxn1 neurexin I 0.750
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.750
Sez6 seizure related gene 6 0.749
Grid2 glutamate receptor, ionotropic, delta 2 0.748
Hand2 heart and neural crest derivatives expressed transcript 2 0.726
C1qa complement component 1, q subcomponent, alpha polypeptide 0.715
Tgfb2 transforming growth factor, beta 2 0.695
Tbx3 T-box 3 0.682
Apc adenomatosis polyposis coli 0.681
Nodal nodal 0.681
Sez6l seizure related 6 homolog like 0.679
Vegfa vascular endothelial growth factor A 0.672
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.658
Fzd8 frizzled homolog 8 (Drosophila) 0.653
Insm1 insulinoma-associated 1 0.653
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.651
Isl1 ISL1 transcription factor, LIM/homeodomain 0.649
Gpc3 glypican 3 0.648
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.638
Sox11 SRY-box containing gene 11 0.635
Bmp7 bone morphogenetic protein 7 0.629
Sqstm1 sequestosome 1 0.627
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.621
Ret ret proto-oncogene 0.614
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.605
Shox2 short stature homeobox 2 0.603
Bdnf brain derived neurotrophic factor 0.589
Zeb1 zinc finger E-box binding homeobox 1 0.585
Hes5 hairy and enhancer of split 5 (Drosophila) 0.584
Sox9 SRY-box containing gene 9 0.566
Gsk3b glycogen synthase kinase 3 beta 0.563
Lmx1a LIM homeobox transcription factor 1 alpha 0.562
Lhx9 LIM homeobox protein 9 0.554
Foxg1 forkhead box G1 0.554
App amyloid beta (A4) precursor protein 0.552
Pou3f2 POU domain, class 3, transcription factor 2 0.551
Ar androgen receptor 0.551
Zic1 zinc finger protein of the cerebellum 1 0.538
Gdnf glial cell line derived neurotrophic factor 0.533
Rarb retinoic acid receptor, beta 0.532
Gopc golgi associated PDZ and coiled-coil motif containing 0.524
Adra2a adrenergic receptor, alpha 2a 0.513
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.508
Msx1 homeobox, msh-like 1 0.507
Pou3f3 POU domain, class 3, transcription factor 3 0.498
Zic4 zinc finger protein of the cerebellum 4 0.497
Gas1 growth arrest specific 1 0.496
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.495
Braf Braf transforming gene 0.492
Fgf15 fibroblast growth factor 15 0.491
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.489
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
fgf8a fibroblast growth factor 8 a 0.856
hnf1ba HNF1 homeobox Ba 0.733
wnt1 wingless-type MMTV integration site family, member 1 0.659
shha sonic hedgehog a 0.595
dbx1a developing brain homeobox 1a 0.464
eng2a engrailed 2a 0.349
fgf3 fibroblast growth factor 3 0.331
wnt8b wingless-type MMTV integration site family, member 8b 0.266
ascl1a achaete-scute complex-like 1a (Drosophila) 0.227
gpia glucose phosphate isomerase a 0.210
foxa2 forkhead box A2 0.203
eng2b engrailed 2b 0.188
hmx4 H6 family homeobox 4 0.162
dld deltaD 0.140
wnt4a wingless-type MMTV integration site family, member 4a 0.133
sox10 SRY-box containing gene 10 0.133
gbx2 gastrulation brain homeo box 2 0.126
st8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.124
gli1 GLI-Kruppel family member 1 0.120
wnt2 wingless-type MMTV integration site family member 2 0.115
pax2a paired box gene 2a 0.111
cdh2 cadherin 2, neuronal 0.105
irx4a iroquois homeobox protein 4a 0.105
isl1 islet1 0.105
dkk1b dickkopf 1b 0.101
dab1b disabled homolog 1b (Drosophila) 0.099
atoh1a atonal homolog 1a 0.099
ptf1a pancreas specific transcription factor, 1a 0.086
tbx1 T-box 1 0.084
gata2a GATA-binding protein 2a 0.083
sox9b SRY-box containing gene 9b 0.077
chd chordin 0.075
nkx6.2 NK6 transcription factor related, locus 2 0.073
lef1 lymphocyte enhancer binding factor 1 0.071
ptch2 patched 2 0.069
hhip hedgehog interacting protein 0.069
her5 hairy-related 5 0.067
gbx1 gastrulation brain homeobox 1 0.064
ghrl ghrelin/obestatin preprohormone 0.061
egr2b early growth response 2b 0.061
neurog1 neurogenin 1 0.054
dharma dharma 0.051
slc9a3.2 solute carrier family 9 (sodium/hydrogen exchanger), member 3.2 0.046
map2k4a mitogen-activated protein kinase kinase 4a 0.046
zbtb4 zinc finger and BTB domain containing 4 0.045
neurod neurogenic differentiation 0.045
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.043
irx4b iroquois homeobox protein 4b 0.042
ncam1a neural cell adhesion molecule 1a 0.041
esrra estrogen-related receptor alpha 0.040
roraa RAR-related orphan receptor A, paralog a 0.039
limk2 LIM domain kinase 2 0.038
pou3f2 POU class 3 homeobox 2 0.037
spry2 sprouty homolog 2 0.036
otpb orthopedia homolog b 0.035
bhmt betaine-homocysteine methyltransferase 0.035
zfyve26 zinc finger, FYVE domain containing 26 0.034
zic3 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) 0.033
nkx2.2a NK2 transcription factor related 2a 0.033
aldob aldolase b, fructose-bisphosphate 0.032
dla deltaA 0.032
raraa retinoic acid receptor, alpha a 0.031
pdlim4 PDZ and LIM domain 4 0.031
gdnf glial cell derived neurotrophic factor 0.031
lmx1b.2 LIM homeobox transcription factor 1, beta 2 0.031
pdlim3a PDZ and LIM domain 3a 0.031
fzd5 frizzled homolog 5 0.031
dlx2a distal-less homeobox gene 2a 0.030
gcm2 glial cells missing homolog 2 (Drosophila) 0.030
si:ch211-173o4.2 si:ch211-173o4.2 0.029
fgf8b fibroblast growth factor 8 b 0.029
crabp2a cellular retinoic acid binding protein 2, a 0.028
dlx1a distal-less homeobox gene 1a 0.028
sox11a SRY-box containing gene 11a 0.027
irx7 iroquois homeobox protein 7 0.027
epha4b eph receptor A4b 0.027
cdx4 caudal type homeo box transcription factor 4 0.027
flh floating head 0.026
evx1 even-skipped homeobox 1 0.026
fezf2 FEZ family zinc finger 2 0.026
sox32 SRY-box containing gene 32 0.026
e2f5 E2F transcription factor 5 0.026
wnt5b wingless-type MMTV integration site family, member 5b 0.025
dlx6a distal-less homeobox gene 6a 0.025
pitx3 paired-like homeodomain transcription factor 3 0.025
gli2a GLI-Kruppel family member GLI2a 0.025
wnt3 wingless-type MMTV integration site family, member 3 0.025
sox2 SRY-box containing gene 2 0.025
bmi1b B lymphoma Mo-MLV insertion region 1b 0.025
olig4 oligodendrocyte transcription factor 4 0.024
tbx16 T-box gene 16 0.024
mtp microsomal triglyceride transfer protein 0.024
pax6b paired box gene 6b 0.024
otpa orthopedia homolog a 0.023
ar androgen receptor 0.023
sst1.1 somatostatin 1, tandem duplicate 1 0.023
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.023
brpf1 bromodomain and PHD finger containing, 1 0.023
ldb2b LIM-domain binding factor 2b 0.022
eve1 even-skipped-like1 0.022
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
ESR1 estrogen receptor 1 0.977
PDZD11 PDZ domain containing 11 0.810
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.756
SKI v-ski sarcoma viral oncogene homolog (avian) 0.731
RUNX1 runt-related transcription factor 1 0.695
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.688
PPP5C protein phosphatase 5, catalytic subunit 0.640
HIPK2 homeodomain interacting protein kinase 2 0.630
AR androgen receptor 0.617
MPDZ multiple PDZ domain protein 0.585
RPL18A ribosomal protein L18a 0.582
SESN2 sestrin 2 0.571
EP300 E1A binding protein p300 0.558
MAFA v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 0.547
CHDH choline dehydrogenase 0.512
SNTG2 syntrophin, gamma 2 0.498
PTCH1 patched 1 0.483
LMO4 LIM domain only 4 0.469
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 0.424
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.395
SETD8 SET domain containing (lysine methyltransferase) 8 0.373
ATG13 ATG13 autophagy related 13 homolog (S. cerevisiae) 0.365
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.335
NCOA1 nuclear receptor coactivator 1 0.322
COPB1 coatomer protein complex, subunit beta 1 0.296
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.259
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.256
DDX17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 0.251
NRXN1 neurexin 1 0.244
GATA2 GATA binding protein 2 0.241
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.239
HNF4A hepatocyte nuclear factor 4, alpha 0.225
MYLK2 myosin light chain kinase 2 0.206
MYOD1 myogenic differentiation 1 0.204
FGF3 fibroblast growth factor 3 0.197
NCOA3 nuclear receptor coactivator 3 0.191
HOXD12 homeobox D12 0.191
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.187
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.186
SOX1 SRY (sex determining region Y)-box 1 0.184
HYOU1 hypoxia up-regulated 1 0.180
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.169
KAT2B K(lysine) acetyltransferase 2B 0.168
ULK2 unc-51-like kinase 2 (C. elegans) 0.163
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.161
CALCA calcitonin-related polypeptide alpha 0.158
LHX3 LIM homeobox 3 0.156
DKK1 dickkopf homolog 1 (Xenopus laevis) 0.156
ARID1B AT rich interactive domain 1B (SWI1-like) 0.155
MYO16 myosin XVI 0.150
TCF12 transcription factor 12 0.143
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C 0.142
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.141
NDP Norrie disease (pseudoglioma) 0.140
LPL lipoprotein lipase 0.139
SSTR2 somatostatin receptor 2 0.139
NCOR1 nuclear receptor corepressor 1 0.139
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.139
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.126
APC adenomatous polyposis coli 0.126
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.125
LSAMP limbic system-associated membrane protein 0.125
POU4F3 POU class 4 homeobox 3 0.123
NEGR1 neuronal growth regulator 1 0.122
GATA4 GATA binding protein 4 0.119
LPHN1 latrophilin 1 0.117
SRRM4 serine/arginine repetitive matrix 4 0.116
RLIM ring finger protein, LIM domain interacting 0.114
CREBBP CREB binding protein 0.113
PTN pleiotrophin 0.113
TP73 tumor protein p73 0.112
HNF1A HNF1 homeobox A 0.111
DDX5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 0.107
SIX6 SIX homeobox 6 0.106
PBX1 pre-B-cell leukemia homeobox 1 0.105
MET met proto-oncogene (hepatocyte growth factor receptor) 0.104
KCNQ2 potassium voltage-gated channel, KQT-like subfamily, member 2 0.102
ACTL6B actin-like 6B 0.101
DLG2 discs, large homolog 2 (Drosophila) 0.101
NPAS1 neuronal PAS domain protein 1 0.099
SSTR3 somatostatin receptor 3 0.098
ZNF512B zinc finger protein 512B 0.098
DDX24 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 0.096
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 0.096
WNT3A wingless-type MMTV integration site family, member 3A 0.091
ALAS1 aminolevulinate, delta-, synthase 1 0.090
CTBP2 C-terminal binding protein 2 0.090
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 0.086
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.084
TRIM33 tripartite motif containing 33 0.084
FOXB1 forkhead box B1 0.083
ARHGAP22 Rho GTPase activating protein 22 0.083
COPG coatomer protein complex, subunit gamma 0.082
POU4F2 POU class 4 homeobox 2 0.082
ATXN1 ataxin 1 0.081
RAX retina and anterior neural fold homeobox 0.080
NFIB nuclear factor I/B 0.078
ZIC1 Zic family member 1 (odd-paired homolog, Drosophila) 0.078
CABLES1 Cdk5 and Abl enzyme substrate 1 0.077
LRRK2 leucine-rich repeat kinase 2 0.077
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Kcnk3 potassium channel, subfamily K, member 3 0.016
Aqp2 aquaporin 2 (collecting duct) 0.014
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.014
Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 0.013
Bcl2 B-cell CLL/lymphoma 2 0.013
Slc6a7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 0.013
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.012
Cntn3 contactin 3 (plasmacytoma associated) 0.012
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.012
ATP6 ATPase subunit 6 0.012
Galr3 galanin receptor 3 0.012
Tusc3 tumor suppressor candidate 3 0.012
Grm1 glutamate receptor, metabotropic 1 0.011
Nxph1 neurexophilin 1 0.011
Atp12a ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.011
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.011
Epor erythropoietin receptor 0.011
Gja1 gap junction protein, alpha 1 0.011
Gja6 gap junction protein, alpha 6 0.011
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.011
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.011
Cdh22 cadherin 22 0.011
Prlhr prolactin releasing hormone receptor 0.011
Snap91 synaptosomal-associated protein 91 0.011
Uhmk1 U2AF homology motif (UHM) kinase 1 0.011
Gad1 glutamate decarboxylase 1 0.011
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.011
Dll3 delta-like 3 (Drosophila) 0.010
Kcnc2 potassium voltage gated channel, Shaw-related subfamily, member 2 0.010
Svs1 seminal vesicle secretory protein 1 0.010
Sp3 Sp3 transcription factor 0.010
Glp1r glucagon-like peptide 1 receptor 0.010
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 0.010
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism