IMP
Process View
The network for 'negative regulation of ripoptosome assembly involved in necroptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of ripoptosome assembly involved in necroptotic process
Any process that stops, prevents or reduces the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ikbkg | inhibitor of kappaB kinase gamma | 0.999 | |
| Ikbkb | inhibitor of kappaB kinase beta | 0.963 | |
| Traf6 | TNF receptor-associated factor 6 | 0.923 | |
| Traf2 | TNF receptor-associated factor 2 | 0.882 | |
| Chuk | conserved helix-loop-helix ubiquitous kinase | 0.872 | |
| Tgfbr1 | transforming growth factor, beta receptor I | 0.859 | |
| Hccs | holocytochrome c synthetase | 0.759 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.677 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.635 | |
| Tab2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.572 | |
| Tlr4 | toll-like receptor 4 | 0.484 | |
| Skil | SKI-like | 0.462 | |
| Pik3c2a | phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide | 0.279 | |
| Smad5 | MAD homolog 5 (Drosophila) | 0.204 | |
| Smad1 | MAD homolog 1 (Drosophila) | 0.191 | |
| Diablo | diablo homolog (Drosophila) | 0.189 | |
| Casp8 | caspase 8 | 0.187 | |
| Map3k2 | mitogen-activated protein kinase kinase kinase 2 | 0.187 | |
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.179 | |
| Cd40 | CD40 antigen | 0.150 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.133 | |
| Apobec1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 | 0.119 | |
| Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.115 | |
| Foxp3 | forkhead box P3 | 0.114 | |
| Ahr | aryl-hydrocarbon receptor | 0.114 | |
| Naip2 | NLR family, apoptosis inhibitory protein 2 | 0.112 | |
| Map2k4 | mitogen-activated protein kinase kinase 4 | 0.106 | |
| Pten | phosphatase and tensin homolog | 0.094 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.077 | |
| Map3k1 | mitogen-activated protein kinase kinase kinase 1 | 0.076 | |
| Tab1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | 0.075 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.072 | |
| Naip5 | NLR family, apoptosis inhibitory protein 5 | 0.067 | |
| Malt1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.064 | |
| Irak1 | interleukin-1 receptor-associated kinase 1 | 0.061 | |
| Birc3 | baculoviral IAP repeat-containing 3 | 0.060 | |
| Card11 | caspase recruitment domain family, member 11 | 0.052 | |
| Cytip | cytohesin 1 interacting protein | 0.052 | |
| Naip6 | NLR family, apoptosis inhibitory protein 6 | 0.051 | |
| A230046K03Rik | RIKEN cDNA A230046K03 gene | 0.050 | |
| Zufsp | zinc finger with UFM1-specific peptidase domain | 0.048 | |
| Il10 | interleukin 10 | 0.046 | |
| Tax1bp1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.042 | |
| Tfrc | transferrin receptor | 0.041 | |
| Trp53 | transformation related protein 53 | 0.041 | |
| Htra2 | HtrA serine peptidase 2 | 0.038 | |
| Chd2 | chromodomain helicase DNA binding protein 2 | 0.038 | |
| Stk3 | serine/threonine kinase 3 (Ste20, yeast homolog) | 0.037 | |
| Pikfyve | phosphoinositide kinase, FYVE finger containing | 0.036 | |
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.035 | |
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.032 | |
| Mx1 | myxovirus (influenza virus) resistance 1 | 0.032 | |
| Lair1 | leukocyte-associated Ig-like receptor 1 | 0.030 | |
| Cyld | cylindromatosis (turban tumor syndrome) | 0.030 | |
| Tbce | tubulin-specific chaperone E | 0.027 | |
| Casp1 | caspase 1 | 0.027 | |
| Atp7a | ATPase, Cu++ transporting, alpha polypeptide | 0.027 | |
| Itch | itchy, E3 ubiquitin protein ligase | 0.026 | |
| Nlrc5 | NLR family, CARD domain containing 5 | 0.025 | |
| Nfkbiz | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.025 | |
| Ly96 | lymphocyte antigen 96 | 0.025 | |
| Braf | Braf transforming gene | 0.024 | |
| Pyhin1 | pyrin and HIN domain family, member 1 | 0.024 | |
| Nr2c2 | nuclear receptor subfamily 2, group C, member 2 | 0.022 | |
| Il6st | interleukin 6 signal transducer | 0.022 | |
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.021 | |
| Hspa1b | heat shock protein 1B | 0.021 | |
| Ate1 | arginyltransferase 1 | 0.020 | |
| Cd33 | CD33 antigen | 0.020 | |
| Lpxn | leupaxin | 0.020 | |
| Kif5b | kinesin family member 5B | 0.019 | |
| Bcl10 | B-cell leukemia/lymphoma 10 | 0.019 | |
| Tlr2 | toll-like receptor 2 | 0.019 | |
| Klra9 | killer cell lectin-like receptor subfamily A, member 9 | 0.019 | |
| Slc35a3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3 | 0.019 | |
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.019 | |
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.019 | |
| Frk | fyn-related kinase | 0.018 | |
| Snx13 | sorting nexin 13 | 0.018 | |
| Ms4a6b | membrane-spanning 4-domains, subfamily A, member 6B | 0.018 | |
| Lcor | ligand dependent nuclear receptor corepressor | 0.018 | |
| Jag1 | jagged 1 | 0.018 | |
| Atp11c | ATPase, class VI, type 11C | 0.018 | |
| Tbk1 | TANK-binding kinase 1 | 0.018 | |
| Fpr2 | formyl peptide receptor 2 | 0.018 | |
| Abcb4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 | 0.017 | |
| Klhl24 | kelch-like 24 (Drosophila) | 0.017 | |
| Zcchc6 | zinc finger, CCHC domain containing 6 | 0.017 | |
| Usp12 | ubiquitin specific peptidase 12 | 0.017 | |
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.016 | |
| Cd84 | CD84 antigen | 0.016 | |
| Cd86 | CD86 antigen | 0.016 | |
| Atrx | alpha thalassemia/mental retardation syndrome X-linked homolog (human) | 0.016 | |
| Adamdec1 | ADAM-like, decysin 1 | 0.016 | |
| Zfp40 | zinc finger protein 40 | 0.016 | |
| Xrn1 | 5'-3' exoribonuclease 1 | 0.016 | |
| Stk17b | serine/threonine kinase 17b (apoptosis-inducing) | 0.016 | |
| BC006779 | cDNA sequence BC006779 | 0.016 | |
| Cflar | CASP8 and FADD-like apoptosis regulator | 0.015 | |
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.015 |
