The network for 'ventricular cardiac myofibril assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

ventricular cardiac myofibril assembly

The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.

Name Description Probability Func Analog Organism
Hand2 heart and neural crest derivatives expressed transcript 2 1.000
Shh sonic hedgehog 1.000
Fgf8 fibroblast growth factor 8 1.000
Hand1 heart and neural crest derivatives expressed transcript 1 0.999
Pitx2 paired-like homeodomain transcription factor 2 0.997
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.997
Gata4 GATA binding protein 4 0.993
Tbx1 T-box 1 0.992
Sox9 SRY-box containing gene 9 0.989
Fgfr2 fibroblast growth factor receptor 2 0.972
Foxc1 forkhead box C1 0.972
Mesp1 mesoderm posterior 1 0.970
Foxc2 forkhead box C2 0.966
Tgfb2 transforming growth factor, beta 2 0.953
Ntf3 neurotrophin 3 0.951
Isl1 ISL1 transcription factor, LIM/homeodomain 0.945
Tbx5 T-box 5 0.943
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.933
Gata6 GATA binding protein 6 0.921
Pax3 paired box gene 3 0.866
Gsc goosecoid homeobox 0.865
Vegfa vascular endothelial growth factor A 0.854
Gja5 gap junction protein, alpha 5 0.833
Nkx6-1 NK6 homeobox 1 0.793
Rxra retinoid X receptor alpha 0.792
Prrx1 paired related homeobox 1 0.790
Tcfap2a transcription factor AP-2, alpha 0.768
Pitx1 paired-like homeodomain transcription factor 1 0.749
Bmp4 bone morphogenetic protein 4 0.724
Tbx3 T-box 3 0.694
Gli2 GLI-Kruppel family member GLI2 0.692
Msx1 homeobox, msh-like 1 0.691
Fgf10 fibroblast growth factor 10 0.663
Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 0.661
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.622
Eya1 eyes absent 1 homolog (Drosophila) 0.601
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.583
Nog noggin 0.572
Hdac4 histone deacetylase 4 0.571
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.569
Ldb3 LIM domain binding 3 0.520
Rarb retinoic acid receptor, beta 0.518
Nkx3-2 NK3 homeobox 2 0.511
Acvr1 activin A receptor, type 1 0.505
Nkx2-6 NK2 transcription factor related, locus 6 (Drosophila) 0.497
Chrd chordin 0.480
Hoxd13 homeobox D13 0.476
Lmx1b LIM homeobox transcription factor 1 beta 0.475
Otp orthopedia homolog (Drosophila) 0.473
Scn5a sodium channel, voltage-gated, type V, alpha 0.471
Rarg retinoic acid receptor, gamma 0.460
Pdx1 pancreatic and duodenal homeobox 1 0.453
Hdac5 histone deacetylase 5 0.451
Zfpm2 zinc finger protein, multitype 2 0.450
Hoxa1 homeobox A1 0.447
Hoxa13 homeobox A13 0.434
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.434
Jag1 jagged 1 0.428
Alx3 aristaless-like homeobox 3 0.421
Ednra endothelin receptor type A 0.419
Kcnk3 potassium channel, subfamily K, member 3 0.416
Otx2 orthodenticle homolog 2 (Drosophila) 0.414
Gata5 GATA binding protein 5 0.391
Col2a1 collagen, type II, alpha 1 0.359
Pax9 paired box gene 9 0.351
Tcf15 transcription factor 15 0.348
Tgfbr2 transforming growth factor, beta receptor II 0.328
Foxa2 forkhead box A2 0.321
Vax1 ventral anterior homeobox containing gene 1 0.313
Hoxd3 homeobox D3 0.312
Fgf3 fibroblast growth factor 3 0.294
Alx4 aristaless-like homeobox 4 0.293
Efnb2 ephrin B2 0.288
Myl3 myosin, light polypeptide 3 0.270
Rara retinoic acid receptor, alpha 0.263
Xirp1 xin actin-binding repeat containing 1 0.261
Tcf21 transcription factor 21 0.260
Hrc histidine rich calcium binding protein 0.258
Hoxa3 homeobox A3 0.256
Fgfr1 fibroblast growth factor receptor 1 0.248
Krt15 keratin 15 0.229
Atoh7 atonal homolog 7 (Drosophila) 0.227
Fgf17 fibroblast growth factor 17 0.226
Meox2 mesenchyme homeobox 2 0.225
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.222
Bmpr1a bone morphogenetic protein receptor, type 1A 0.220
Zeb1 zinc finger E-box binding homeobox 1 0.217
Dlx5 distal-less homeobox 5 0.207
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.203
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.202
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.200
Pitx3 paired-like homeodomain transcription factor 3 0.197
Hmx1 H6 homeobox 1 0.190
Pcdh12 protocadherin 12 0.188
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.178
Wnt3a wingless-related MMTV integration site 3A 0.177
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.175
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.174
Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.165
Foxg1 forkhead box G1 0.165
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
vmhc ventricular myosin heavy chain 0.933
ttnb titin b 0.909
mylz2 myosin, light polypeptide 2, skeletal muscle 0.905
myl7 myosin, light polypeptide 7, regulatory 0.810
myl1 myosin, light chain 1, alkali; skeletal, fast 0.773
ttna titin a 0.758
tnnc2 troponin C type 2 (fast) 0.751
tnnc1b troponin C type 1b (slow) 0.648
actc1a actin, alpha, cardiac muscle 1a 0.607
atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.547
myl10 myosin, light chain 10, regulatory 0.499
mylz3 myosin, light polypeptide 3, skeletal muscle 0.495
zgc:165344 zgc:165344 0.446
zgc:66286 zgc:66286 0.439
actn3b actinin alpha 3b 0.429
acta1a actin, alpha 1a, skeletal muscle 0.416
desma desmin a 0.414
actc1b actin, alpha, cardiac muscle 1b 0.414
ckma creatine kinase, muscle a 0.410
tpma alpha-tropomyosin 0.406
tmem38a transmembrane protein 38A 0.310
tnnt3b troponin T3b, skeletal, fast 0.304
chrna1 cholinergic receptor, nicotinic, alpha polypeptide 1 0.293
tnni2a.4 troponin I, skeletal, fast 2a.4 0.258
ckmb creatine kinase, muscle b 0.254
pvalb2 parvalbumin 2 0.177
aldoab aldolase a, fructose-bisphosphate, b 0.170
casq2 calsequestrin 2 0.146
neb nebulin 0.145
myog myogenin 0.124
cav3 caveolin 3 0.120
kbtbd10b kelch repeat and BTB (POZ) domain containing 10b 0.118
acta1b actin, alpha 1b, skeletal muscle 0.114
ldb3b LIM domain binding 3b 0.111
tnnt3a troponin T3a, skeletal, fast 0.102
tnni1b troponin I, skeletal, slow b 0.097
pabpc4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.093
prox1 prospero-related homeobox gene 1 0.084
hsp90a.1 heat shock protein 90-alpha 1 0.082
pvalb4 parvalbumin 4 0.079
ns:zf-e68 ns:zf-e68 0.077
tnni2b.1 troponin I, skeletal, fast 2b.1 0.074
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.070
mef2ca myocyte enhancer factor 2ca 0.070
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.067
tgfb3 transforming growth factor, beta 3 0.054
rbfox1l RNA binding protein, fox-1 homolog (C. elegans) 1-like 0.053
tnnc1a troponin C type 1a (slow) 0.053
nexn nexilin (F actin binding protein) 0.048
jam2a junctional adhesion molecule 2a 0.046
smyd1b SET and MYND domain containing 1b 0.043
scn12ab sodium channel, voltage gated, type XII, alpha b 0.040
atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide 0.038
atp2a2a ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a 0.038
tnnt1 troponin T1, skeletal, slow 0.036
slc8a1a solute carrier family 8 (sodium/calcium exchanger), member 1a 0.036
srl sarcalumenin 0.035
mef2d myocyte enhancer factor 2d 0.034
myod1 myogenic differentiation 1 0.033
cdh5 cadherin 5 0.032
tnni1al troponin I, skeletal, slow like 0.032
cmlc1 cardiac myosin light chain-1 0.029
rbm24b RNA binding motif protein 24b 0.028
egr1 early growth response 1 0.027
smyhc1 slow myosin heavy chain 1 0.027
scn2b sodium channel, voltage-gated, type II, beta 0.027
tbx5b T-box 5b 0.026
tpm3 tropomyosin 3 0.024
tpm2 tropomyosin 2 (beta) 0.024
pvalb1 parvalbumin 1 0.023
tcf21 transcription factor 21 0.022
nkx2.5 NK2 transcription factor related 5 0.021
myhz1.1 myosin, heavy polypeptide 1.1, skeletal muscle 0.021
wu:fc31e07 wu:fc31e07 0.020
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.020
unc45b unc-45 homolog B (C. elegans) 0.019
scn12aa sodium channel, voltage gated, type XII, alpha a 0.019
lrrc10 leucine rich repeat containing 10 0.019
actn2 actinin, alpha 2 0.018
dpf3 D4, zinc and double PHD fingers, family 3 0.018
dedd1 death effector domain-containing 1 0.018
nr4a2b nuclear receptor subfamily 4, group A, member 2b 0.017
synpo2lb synaptopodin 2-like b 0.017
popdc2 popeye domain containing 2 0.017
ogg1 8-oxoguanine DNA glycosylase 0.017
nr2f2 nuclear receptor subfamily 2, group F, member 2 0.017
wu:fb01h12 wu:fb01h12 0.017
sema3aa semaphorin 3aa 0.017
tgfbr2 transforming growth factor, beta receptor II 0.016
csrp3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.016
ldb3a LIM-domain binding factor 3a 0.016
smyhc2 slow myosin heavy chain 2 0.015
dusp5 dual specificity phosphatase 5 0.015
ret1 receptor tyrosine kinase 0.014
slc25a4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.014
mrrf mitochondrial ribosome recycling factor 0.013
mbnl2 muscleblind-like 2 (Drosophila) 0.013
phf2 PHD finger protein 2 0.013
mpp6a membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6) 0.012
dub duboraya 0.012
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism