Process View
The network for 'ventricular cardiac myofibril assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Hand2 | heart and neural crest derivatives expressed transcript 2 | 1.000 | |
Shh | sonic hedgehog | 1.000 | |
Fgf8 | fibroblast growth factor 8 | 1.000 | |
Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.999 | |
Pitx2 | paired-like homeodomain transcription factor 2 | 0.997 | |
Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.997 | |
Gata4 | GATA binding protein 4 | 0.993 | |
Tbx1 | T-box 1 | 0.992 | |
Sox9 | SRY-box containing gene 9 | 0.989 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.972 | |
Foxc1 | forkhead box C1 | 0.972 | |
Mesp1 | mesoderm posterior 1 | 0.970 | |
Foxc2 | forkhead box C2 | 0.966 | |
Tgfb2 | transforming growth factor, beta 2 | 0.953 | |
Ntf3 | neurotrophin 3 | 0.951 | |
Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.945 | |
Tbx5 | T-box 5 | 0.943 | |
Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.933 | |
Gata6 | GATA binding protein 6 | 0.921 | |
Pax3 | paired box gene 3 | 0.866 | |
Gsc | goosecoid homeobox | 0.865 | |
Vegfa | vascular endothelial growth factor A | 0.854 | |
Gja5 | gap junction protein, alpha 5 | 0.833 | |
Nkx6-1 | NK6 homeobox 1 | 0.793 | |
Rxra | retinoid X receptor alpha | 0.792 | |
Prrx1 | paired related homeobox 1 | 0.790 | |
Tcfap2a | transcription factor AP-2, alpha | 0.768 | |
Pitx1 | paired-like homeodomain transcription factor 1 | 0.749 | |
Bmp4 | bone morphogenetic protein 4 | 0.724 | |
Tbx3 | T-box 3 | 0.694 | |
Gli2 | GLI-Kruppel family member GLI2 | 0.692 | |
Msx1 | homeobox, msh-like 1 | 0.691 | |
Fgf10 | fibroblast growth factor 10 | 0.663 | |
Kcnj5 | potassium inwardly-rectifying channel, subfamily J, member 5 | 0.661 | |
Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.622 | |
Eya1 | eyes absent 1 homolog (Drosophila) | 0.601 | |
Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.583 | |
Nog | noggin | 0.572 | |
Hdac4 | histone deacetylase 4 | 0.571 | |
Six3 | sine oculis-related homeobox 3 homolog (Drosophila) | 0.569 | |
Ldb3 | LIM domain binding 3 | 0.520 | |
Rarb | retinoic acid receptor, beta | 0.518 | |
Nkx3-2 | NK3 homeobox 2 | 0.511 | |
Acvr1 | activin A receptor, type 1 | 0.505 | |
Nkx2-6 | NK2 transcription factor related, locus 6 (Drosophila) | 0.497 | |
Chrd | chordin | 0.480 | |
Hoxd13 | homeobox D13 | 0.476 | |
Lmx1b | LIM homeobox transcription factor 1 beta | 0.475 | |
Otp | orthopedia homolog (Drosophila) | 0.473 | |
Scn5a | sodium channel, voltage-gated, type V, alpha | 0.471 | |
Rarg | retinoic acid receptor, gamma | 0.460 | |
Pdx1 | pancreatic and duodenal homeobox 1 | 0.453 | |
Hdac5 | histone deacetylase 5 | 0.451 | |
Zfpm2 | zinc finger protein, multitype 2 | 0.450 | |
Hoxa1 | homeobox A1 | 0.447 | |
Hoxa13 | homeobox A13 | 0.434 | |
Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.434 | |
Jag1 | jagged 1 | 0.428 | |
Alx3 | aristaless-like homeobox 3 | 0.421 | |
Ednra | endothelin receptor type A | 0.419 | |
Kcnk3 | potassium channel, subfamily K, member 3 | 0.416 | |
Otx2 | orthodenticle homolog 2 (Drosophila) | 0.414 | |
Gata5 | GATA binding protein 5 | 0.391 | |
Col2a1 | collagen, type II, alpha 1 | 0.359 | |
Pax9 | paired box gene 9 | 0.351 | |
Tcf15 | transcription factor 15 | 0.348 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.328 | |
Foxa2 | forkhead box A2 | 0.321 | |
Vax1 | ventral anterior homeobox containing gene 1 | 0.313 | |
Hoxd3 | homeobox D3 | 0.312 | |
Fgf3 | fibroblast growth factor 3 | 0.294 | |
Alx4 | aristaless-like homeobox 4 | 0.293 | |
Efnb2 | ephrin B2 | 0.288 | |
Myl3 | myosin, light polypeptide 3 | 0.270 | |
Rara | retinoic acid receptor, alpha | 0.263 | |
Xirp1 | xin actin-binding repeat containing 1 | 0.261 | |
Tcf21 | transcription factor 21 | 0.260 | |
Hrc | histidine rich calcium binding protein | 0.258 | |
Hoxa3 | homeobox A3 | 0.256 | |
Fgfr1 | fibroblast growth factor receptor 1 | 0.248 | |
Krt15 | keratin 15 | 0.229 | |
Atoh7 | atonal homolog 7 (Drosophila) | 0.227 | |
Fgf17 | fibroblast growth factor 17 | 0.226 | |
Meox2 | mesenchyme homeobox 2 | 0.225 | |
Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.222 | |
Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.220 | |
Zeb1 | zinc finger E-box binding homeobox 1 | 0.217 | |
Dlx5 | distal-less homeobox 5 | 0.207 | |
Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.203 | |
Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.202 | |
Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.200 | |
Pitx3 | paired-like homeodomain transcription factor 3 | 0.197 | |
Hmx1 | H6 homeobox 1 | 0.190 | |
Pcdh12 | protocadherin 12 | 0.188 | |
Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.178 | |
Wnt3a | wingless-related MMTV integration site 3A | 0.177 | |
Kcnj11 | potassium inwardly rectifying channel, subfamily J, member 11 | 0.175 | |
Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.174 | |
Myh6 | myosin, heavy polypeptide 6, cardiac muscle, alpha | 0.165 | |
Foxg1 | forkhead box G1 | 0.165 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
vmhc | ventricular myosin heavy chain | 0.933 | |
ttnb | titin b | 0.909 | |
mylz2 | myosin, light polypeptide 2, skeletal muscle | 0.905 | |
myl7 | myosin, light polypeptide 7, regulatory | 0.810 | |
myl1 | myosin, light chain 1, alkali; skeletal, fast | 0.773 | |
ttna | titin a | 0.758 | |
tnnc2 | troponin C type 2 (fast) | 0.751 | |
tnnc1b | troponin C type 1b (slow) | 0.648 | |
actc1a | actin, alpha, cardiac muscle 1a | 0.607 | |
atp2a1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 0.547 | |
myl10 | myosin, light chain 10, regulatory | 0.499 | |
mylz3 | myosin, light polypeptide 3, skeletal muscle | 0.495 | |
zgc:165344 | zgc:165344 | 0.446 | |
zgc:66286 | zgc:66286 | 0.439 | |
actn3b | actinin alpha 3b | 0.429 | |
acta1a | actin, alpha 1a, skeletal muscle | 0.416 | |
desma | desmin a | 0.414 | |
actc1b | actin, alpha, cardiac muscle 1b | 0.414 | |
ckma | creatine kinase, muscle a | 0.410 | |
tpma | alpha-tropomyosin | 0.406 | |
tmem38a | transmembrane protein 38A | 0.310 | |
tnnt3b | troponin T3b, skeletal, fast | 0.304 | |
chrna1 | cholinergic receptor, nicotinic, alpha polypeptide 1 | 0.293 | |
tnni2a.4 | troponin I, skeletal, fast 2a.4 | 0.258 | |
ckmb | creatine kinase, muscle b | 0.254 | |
pvalb2 | parvalbumin 2 | 0.177 | |
aldoab | aldolase a, fructose-bisphosphate, b | 0.170 | |
casq2 | calsequestrin 2 | 0.146 | |
neb | nebulin | 0.145 | |
myog | myogenin | 0.124 | |
cav3 | caveolin 3 | 0.120 | |
kbtbd10b | kelch repeat and BTB (POZ) domain containing 10b | 0.118 | |
acta1b | actin, alpha 1b, skeletal muscle | 0.114 | |
ldb3b | LIM domain binding 3b | 0.111 | |
tnnt3a | troponin T3a, skeletal, fast | 0.102 | |
tnni1b | troponin I, skeletal, slow b | 0.097 | |
pabpc4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.093 | |
prox1 | prospero-related homeobox gene 1 | 0.084 | |
hsp90a.1 | heat shock protein 90-alpha 1 | 0.082 | |
pvalb4 | parvalbumin 4 | 0.079 | |
ns:zf-e68 | ns:zf-e68 | 0.077 | |
tnni2b.1 | troponin I, skeletal, fast 2b.1 | 0.074 | |
myhz2 | myosin, heavy polypeptide 2, fast muscle specific | 0.070 | |
mef2ca | myocyte enhancer factor 2ca | 0.070 | |
myh6 | myosin, heavy polypeptide 6, cardiac muscle, alpha | 0.067 | |
tgfb3 | transforming growth factor, beta 3 | 0.054 | |
rbfox1l | RNA binding protein, fox-1 homolog (C. elegans) 1-like | 0.053 | |
tnnc1a | troponin C type 1a (slow) | 0.053 | |
nexn | nexilin (F actin binding protein) | 0.048 | |
jam2a | junctional adhesion molecule 2a | 0.046 | |
smyd1b | SET and MYND domain containing 1b | 0.043 | |
scn12ab | sodium channel, voltage gated, type XII, alpha b | 0.040 | |
atp1b1b | ATPase, Na+/K+ transporting, beta 1b polypeptide | 0.038 | |
atp2a2a | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a | 0.038 | |
tnnt1 | troponin T1, skeletal, slow | 0.036 | |
slc8a1a | solute carrier family 8 (sodium/calcium exchanger), member 1a | 0.036 | |
srl | sarcalumenin | 0.035 | |
mef2d | myocyte enhancer factor 2d | 0.034 | |
myod1 | myogenic differentiation 1 | 0.033 | |
cdh5 | cadherin 5 | 0.032 | |
tnni1al | troponin I, skeletal, slow like | 0.032 | |
cmlc1 | cardiac myosin light chain-1 | 0.029 | |
rbm24b | RNA binding motif protein 24b | 0.028 | |
egr1 | early growth response 1 | 0.027 | |
smyhc1 | slow myosin heavy chain 1 | 0.027 | |
scn2b | sodium channel, voltage-gated, type II, beta | 0.027 | |
tbx5b | T-box 5b | 0.026 | |
tpm3 | tropomyosin 3 | 0.024 | |
tpm2 | tropomyosin 2 (beta) | 0.024 | |
pvalb1 | parvalbumin 1 | 0.023 | |
tcf21 | transcription factor 21 | 0.022 | |
nkx2.5 | NK2 transcription factor related 5 | 0.021 | |
myhz1.1 | myosin, heavy polypeptide 1.1, skeletal muscle | 0.021 | |
wu:fc31e07 | wu:fc31e07 | 0.020 | |
hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.020 | |
unc45b | unc-45 homolog B (C. elegans) | 0.019 | |
scn12aa | sodium channel, voltage gated, type XII, alpha a | 0.019 | |
lrrc10 | leucine rich repeat containing 10 | 0.019 | |
actn2 | actinin, alpha 2 | 0.018 | |
dpf3 | D4, zinc and double PHD fingers, family 3 | 0.018 | |
dedd1 | death effector domain-containing 1 | 0.018 | |
nr4a2b | nuclear receptor subfamily 4, group A, member 2b | 0.017 | |
synpo2lb | synaptopodin 2-like b | 0.017 | |
popdc2 | popeye domain containing 2 | 0.017 | |
ogg1 | 8-oxoguanine DNA glycosylase | 0.017 | |
nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.017 | |
wu:fb01h12 | wu:fb01h12 | 0.017 | |
sema3aa | semaphorin 3aa | 0.017 | |
tgfbr2 | transforming growth factor, beta receptor II | 0.016 | |
csrp3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.016 | |
ldb3a | LIM-domain binding factor 3a | 0.016 | |
smyhc2 | slow myosin heavy chain 2 | 0.015 | |
dusp5 | dual specificity phosphatase 5 | 0.015 | |
ret1 | receptor tyrosine kinase | 0.014 | |
slc25a4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 0.014 | |
mrrf | mitochondrial ribosome recycling factor | 0.013 | |
mbnl2 | muscleblind-like 2 (Drosophila) | 0.013 | |
phf2 | PHD finger protein 2 | 0.013 | |
mpp6a | membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6) | 0.012 | |
dub | duboraya | 0.012 |