The network for 'rhombomere formation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

rhombomere formation

The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.

Mus musculus
Name Description Probability Func Analog Organism
Pax2 paired box gene 2 0.998
Hoxa1 homeobox A1 0.995
Jag1 jagged 1 0.982
Chd7 chromodomain helicase DNA binding protein 7 0.911
Foxc1 forkhead box C1 0.909
Lmx1a LIM homeobox transcription factor 1 alpha 0.852
Tbx1 T-box 1 0.849
Gli3 GLI-Kruppel family member GLI3 0.832
Fgfr1 fibroblast growth factor receptor 1 0.813
Gata3 GATA binding protein 3 0.797
Vangl2 vang-like 2 (van gogh, Drosophila) 0.788
Gbx2 gastrulation brain homeobox 2 0.779
Foxc2 forkhead box C2 0.762
Nab2 Ngfi-A binding protein 2 0.720
Eya1 eyes absent 1 homolog (Drosophila) 0.718
Dll1 delta-like 1 (Drosophila) 0.709
Ntf3 neurotrophin 3 0.662
Shh sonic hedgehog 0.626
Notch1 Notch gene homolog 1 (Drosophila) 0.607
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.541
Gata4 GATA binding protein 4 0.530
Fos FBJ osteosarcoma oncogene 0.507
Foxg1 forkhead box G1 0.501
Foxo1 forkhead box O1 0.486
Isl1 ISL1 transcription factor, LIM/homeodomain 0.479
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.455
Fgf8 fibroblast growth factor 8 0.443
Fgfr2 fibroblast growth factor receptor 2 0.419
Emx2 empty spiracles homolog 2 (Drosophila) 0.415
Spry2 sprouty homolog 2 (Drosophila) 0.397
Efnb2 ephrin B2 0.383
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.378
Psen1 presenilin 1 0.367
Lhx1 LIM homeobox protein 1 0.366
Gdnf glial cell line derived neurotrophic factor 0.353
Smo smoothened homolog (Drosophila) 0.325
Egr1 early growth response 1 0.318
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.308
Notch2 Notch gene homolog 2 (Drosophila) 0.306
Hoxa2 homeobox A2 0.297
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.293
Fosb FBJ osteosarcoma oncogene B 0.265
Nog noggin 0.231
Hes1 hairy and enhancer of split 1 (Drosophila) 0.225
Jag2 jagged 2 0.223
Pax3 paired box gene 3 0.206
Pitx2 paired-like homeodomain transcription factor 2 0.189
Lhx9 LIM homeobox protein 9 0.188
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.186
Rxra retinoid X receptor alpha 0.185
Nos3 nitric oxide synthase 3, endothelial cell 0.185
Ret ret proto-oncogene 0.183
Epha4 Eph receptor A4 0.179
Bnc1 basonuclin 1 0.176
Tcfap2a transcription factor AP-2, alpha 0.156
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.152
Jun Jun oncogene 0.151
Egr2 early growth response 2 0.149
Otx2 orthodenticle homolog 2 (Drosophila) 0.147
Bcl2 B-cell leukemia/lymphoma 2 0.146
Ephb2 Eph receptor B2 0.141
Sox9 SRY-box containing gene 9 0.141
Msx1 homeobox, msh-like 1 0.127
Bmp4 bone morphogenetic protein 4 0.125
Tbx10 T-box 10 0.120
Hey1 hairy/enhancer-of-split related with YRPW motif 1 0.116
Sox2 SRY-box containing gene 2 0.112
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.110
Hand2 heart and neural crest derivatives expressed transcript 2 0.109
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.109
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.107
Dlx5 distal-less homeobox 5 0.101
Hmx3 H6 homeobox 3 0.099
Wiz widely-interspaced zinc finger motifs 0.098
Junb Jun-B oncogene 0.094
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.094
En1 engrailed 1 0.087
Socs3 suppressor of cytokine signaling 3 0.087
Ar androgen receptor 0.083
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.082
Efna2 ephrin A2 0.082
Zeb1 zinc finger E-box binding homeobox 1 0.081
Ptpn14 protein tyrosine phosphatase, non-receptor type 14 0.080
Efnb1 ephrin B1 0.076
Tgfb2 transforming growth factor, beta 2 0.075
Chrd chordin 0.075
Nrg1 neuregulin 1 0.074
Hoxb2 homeobox B2 0.068
Bdnf brain derived neurotrophic factor 0.067
Otx1 orthodenticle homolog 1 (Drosophila) 0.067
Gfra3 glial cell line derived neurotrophic factor family receptor alpha 3 0.063
Phox2b paired-like homeobox 2b 0.063
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.063
Zfp651 zinc finger protein 651 0.061
Tgif2 TGFB-induced factor homeobox 2 0.059
Ptgs2 prostaglandin-endoperoxide synthase 2 0.058
Hoxc8 homeobox C8 0.057
Fgf3 fibroblast growth factor 3 0.057
Hdac7 histone deacetylase 7 0.056
Hoxa11 homeobox A11 0.056
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
hoxb2a homeo box B2a 0.933
dlc deltaC 0.746
epha4a eph receptor A4a 0.736
efnb3b ephrin B3b 0.693
hoxb1a homeo box B1a 0.672
efna5a ephrin A5a 0.655
esrrga estrogen-related receptor gamma a 0.628
hoxd3a homeo box D3a 0.608
hnf1ba HNF1 homeobox Ba 0.596
egr2a early growth response 2a 0.568
hoxa2b homeo box A2b 0.537
gbx1 gastrulation brain homeobox 1 0.505
ephb4a eph receptor B4a 0.490
msxe muscle segment homeobox E 0.433
hoxb3a homeo box B3a 0.380
egr2b early growth response 2b 0.370
pax2a paired box gene 2a 0.364
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.348
epb4.1l4 erythrocyte protein band 4.1-like 4 0.343
atoh1a atonal homolog 1a 0.335
notch1a notch homolog 1a 0.331
pax8 paired box gene 8 0.327
hoxb1b homeo box B1b 0.322
dusp6 dual specificity phosphatase 6 0.318
her8a hairy-related 8a 0.316
mab21l2 mab-21-like 2 0.274
neurod4 neurogenic differentiation 4 0.255
dld deltaD 0.253
znf703 zinc finger protein 703 0.248
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.245
bmp4 bone morphogenetic protein 4 0.239
wnt3a wingless-type MMTV integration site family, member 3A 0.226
hoxb6a homeo box B6a 0.224
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.223
meis2.2 myeloid ecotropic viral integration site 2.2 0.206
osr2 odd-skipped related 2 (Drosophila) 0.206
ptf1a pancreas specific transcription factor, 1a 0.181
efnb2a ephrin B2a 0.171
znf503 zinc finger protein 503 0.169
znfl2a zinc finger-like gene 2a 0.144
pax6b paired box gene 6b 0.143
foxn4 forkhead box N4 0.142
cdh2 cadherin 2, neuronal 0.140
egr1 early growth response 1 0.135
boc brother of CDO 0.135
lhx1b LIM homeobox 1b 0.129
nkd1 naked cuticle homolog 1 (Drosophila) 0.120
btg2 B-cell translocation gene 2 0.117
onecutl one cut domain, family member, like 0.115
irx7 iroquois homeobox protein 7 0.115
prtga protogenin homolog a (Gallus gallus) 0.110
hoxb4a homeo box B4a 0.110
notch3 notch homolog 3 0.110
tbx16 T-box gene 16 0.108
hoxa3a homeo box A3a 0.106
hoxc6a homeo box C6a 0.104
efnb1 ephrin B1 0.104
smad1 MAD homolog 1 (Drosophila) 0.095
otx1a orthodenticle homolog 1a 0.094
etv2 ets variant gene 2 0.090
spry2 sprouty homolog 2 0.087
six4b sine oculis homeobox homolog 4b 0.086
nkx1.2la NK1 transcription factor related 2-like,a 0.080
elavl3 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) 0.079
crabp2a cellular retinoic acid binding protein 2, a 0.079
lmx1b.2 LIM homeobox transcription factor 1, beta 2 0.079
wnt1 wingless-type MMTV integration site family, member 1 0.078
zbtb16a zinc finger and BTB domain containing 16a 0.076
hnf1bb HNF1 homeobox Bb 0.075
sfrp5 secreted frizzled-related protein 5 0.075
fgf3 fibroblast growth factor 3 0.072
gli1 GLI-Kruppel family member 1 0.071
irx3b iroquois homeobox protein 3b 0.071
hoxa1a homeo box A1a 0.070
hoxc8a homeo box C8a 0.067
rx1 retinal homeobox gene 1 0.066
her12 hairy-related 12 0.066
fzd5 frizzled homolog 5 0.065
vegfaa vascular endothelial growth factor Aa 0.065
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.065
sema3d semaphorin 3d 0.064
tbx6 T-box gene 6 0.062
nkx2.1a NK2 homeobox 1a 0.062
fzd9b frizzled homolog 9b 0.060
msxc muscle segment homeobox C 0.060
gli2a GLI-Kruppel family member GLI2a 0.059
esrra estrogen-related receptor alpha 0.057
scube2 signal peptide, CUB domain, EGF-like 2 0.057
ephb3a eph receptor B3a 0.056
ptprk protein tyrosine phosphatase, receptor type, K 0.054
ncam1a neural cell adhesion molecule 1a 0.053
plagl2 pleiomorphic adenoma gene-like 2 0.052
gata5 GATA-binding protein 5 0.052
wnt8b wingless-type MMTV integration site family, member 8b 0.051
hoxd4a homeo box D4a 0.049
par1 paraxis 0.048
dla deltaA 0.048
hs6st2 heparan sulfate 6-O-sulfotransferase 2 0.047
nr2f5 nuclear receptor subfamily 2, group F, member 5 0.047
tbx5a T-box 5a 0.046
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism