IMP
Process View
The network for 'clara cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
clara cell differentiation
The process in which a relatively unspecialized cell acquires specialized features of a Clara cell. A Clara cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Shh | sonic hedgehog | 1.000 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 1.000 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
| Jag1 | jagged 1 | 1.000 | |
| Tgfb2 | transforming growth factor, beta 2 | 1.000 | |
| Fgf8 | fibroblast growth factor 8 | 1.000 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 1.000 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 1.000 | |
| Rxra | retinoid X receptor alpha | 1.000 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 1.000 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.999 | |
| Bmp4 | bone morphogenetic protein 4 | 0.999 | |
| Sox9 | SRY-box containing gene 9 | 0.999 | |
| Zfpm2 | zinc finger protein, multitype 2 | 0.998 | |
| Vegfa | vascular endothelial growth factor A | 0.997 | |
| Tbx1 | T-box 1 | 0.996 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.994 | |
| Tbx3 | T-box 3 | 0.994 | |
| Mesp1 | mesoderm posterior 1 | 0.992 | |
| Foxc1 | forkhead box C1 | 0.991 | |
| Gata4 | GATA binding protein 4 | 0.990 | |
| Gata6 | GATA binding protein 6 | 0.989 | |
| Foxc2 | forkhead box C2 | 0.988 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.983 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.983 | |
| Pax3 | paired box gene 3 | 0.983 | |
| Klf3 | Kruppel-like factor 3 (basic) | 0.975 | |
| Pten | phosphatase and tensin homolog | 0.973 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.969 | |
| Pax2 | paired box gene 2 | 0.968 | |
| Fgf10 | fibroblast growth factor 10 | 0.966 | |
| Efnb2 | ephrin B2 | 0.964 | |
| Hoxa1 | homeobox A1 | 0.952 | |
| Tbx5 | T-box 5 | 0.950 | |
| Rarg | retinoic acid receptor, gamma | 0.948 | |
| Gata5 | GATA binding protein 5 | 0.924 | |
| Acvr1 | activin A receptor, type 1 | 0.923 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.922 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.922 | |
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.918 | |
| Thra | thyroid hormone receptor alpha | 0.916 | |
| Sox4 | SRY-box containing gene 4 | 0.895 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.893 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.840 | |
| Nfia | nuclear factor I/A | 0.834 | |
| Nfib | nuclear factor I/B | 0.832 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.825 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.822 | |
| Nfix | nuclear factor I/X | 0.804 | |
| Smo | smoothened homolog (Drosophila) | 0.795 | |
| Dll1 | delta-like 1 (Drosophila) | 0.784 | |
| Rarb | retinoic acid receptor, beta | 0.779 | |
| Fgf3 | fibroblast growth factor 3 | 0.776 | |
| Egfr | epidermal growth factor receptor | 0.774 | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.761 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.759 | |
| Sox2 | SRY-box containing gene 2 | 0.749 | |
| Ece1 | endothelin converting enzyme 1 | 0.739 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.736 | |
| Tcf21 | transcription factor 21 | 0.725 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.725 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.716 | |
| Chrd | chordin | 0.685 | |
| Nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.684 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.616 | |
| Efnb1 | ephrin B1 | 0.615 | |
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.614 | |
| Foxf1a | forkhead box F1a | 0.612 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.606 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.600 | |
| Rara | retinoic acid receptor, alpha | 0.599 | |
| Foxa2 | forkhead box A2 | 0.572 | |
| Nkx2-6 | NK2 transcription factor related, locus 6 (Drosophila) | 0.547 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.519 | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.499 | |
| Msx1 | homeobox, msh-like 1 | 0.494 | |
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.493 | |
| Ptf1a | pancreas specific transcription factor, 1a | 0.492 | |
| Meox2 | mesenchyme homeobox 2 | 0.490 | |
| Lhx3 | LIM homeobox protein 3 | 0.483 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.480 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.480 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.469 | |
| Prrx1 | paired related homeobox 1 | 0.465 | |
| Gsc | goosecoid homeobox | 0.462 | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.454 | |
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.446 | |
| Ednra | endothelin receptor type A | 0.423 | |
| Gja5 | gap junction protein, alpha 5 | 0.415 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.408 | |
| Hoxa13 | homeobox A13 | 0.408 | |
| Psen1 | presenilin 1 | 0.405 | |
| Nkx6-1 | NK6 homeobox 1 | 0.396 | |
| Foxg1 | forkhead box G1 | 0.357 | |
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.344 | |
| Nog | noggin | 0.335 | |
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.333 | |
| Hoxd13 | homeobox D13 | 0.331 | |
| Epha1 | Eph receptor A1 | 0.323 | |
| Pitx3 | paired-like homeodomain transcription factor 3 | 0.319 |
