The network for 'regulation of multicellular organismal development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of multicellular organismal development

Any process that modulates the frequency, rate or extent of multicellular organismal development.

Danio rerio
Name Description Probability Func Analog Organism
kdrl kinase insert domain receptor like 0.999
flh floating head 0.998
bmp2b bone morphogenetic protein 2b 0.998
bmp4 bone morphogenetic protein 4 0.996
gli1 GLI-Kruppel family member 1 0.995
runx1 runt-related transcription factor 1 0.994
ndr2 nodal-related 2 0.993
tbx20 T-box 20 0.991
pax2a paired box gene 2a 0.989
gdf6a growth differentiation factor 6a 0.988
tal1 T-cell acute lymphocytic leukemia 1 0.987
gata6 GATA-binding protein 6 0.983
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.981
six3b sine oculis homeobox homolog 3b 0.981
fgf8a fibroblast growth factor 8 a 0.979
fn1 fibronectin 1 0.976
dlc deltaC 0.975
notch3 notch homolog 3 0.974
pitx3 paired-like homeodomain transcription factor 3 0.972
efnb2a ephrin B2a 0.971
ascl1a achaete-scute complex-like 1a (Drosophila) 0.969
fgf3 fibroblast growth factor 3 0.967
egr2b early growth response 2b 0.966
foxa2 forkhead box A2 0.965
gata2a GATA-binding protein 2a 0.964
etv2 ets variant gene 2 0.962
hnf1ba HNF1 homeobox Ba 0.949
crabp2a cellular retinoic acid binding protein 2, a 0.944
lft1 lefty1 0.944
cdh2 cadherin 2, neuronal 0.943
flt4 fms-related tyrosine kinase 4 0.940
nanos3 nanos homolog 3 0.939
dld deltaD 0.938
phox2a paired-like homeobox 2a 0.936
foxi1 forkhead box I1 0.936
gata3 GATA-binding protein 3 0.934
dharma dharma 0.930
pkd2 polycystic kidney disease 2 0.923
foxd3 forkhead box D3 0.919
cdh1 cadherin 1, epithelial 0.917
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.917
her7 hairy and enhancer of split related-7 0.915
cmyb transcription factor cmyb 0.912
tbx2b T-box 2b 0.910
rarab retinoic acid receptor, alpha b 0.905
gro2 groucho 2 0.904
tbx16 T-box gene 16 0.903
bmp2a bone morphogenetic protein 2a 0.901
pax8 paired box gene 8 0.899
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.895
olig2 oligodendrocyte lineage transcription factor 2 0.887
vent ventral expressed homeobox 0.885
tuba1l tubulin, alpha 1, like 0.876
lhx1a LIM homeobox 1a 0.863
jag2 jagged 2 0.860
tbx6 T-box gene 6 0.858
tbx18 T-box 18 0.858
vsx1 visual system homeobox 1 homolog, chx10-like 0.852
hand2 heart and neural crest derivatives expressed transcript 2 0.846
slc17a6b solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b 0.842
tp53 tumor protein p53 0.842
smad7 MAD, mothers against decapentaplegic homolog 7 (Drosophila) 0.841
tbx1 T-box 1 0.836
smad9 MAD homolog 9 (Drosophila) 0.832
eve1 even-skipped-like1 0.832
gli2a GLI-Kruppel family member GLI2a 0.831
ntla no tail a 0.827
fezf2 FEZ family zinc finger 2 0.827
ptch2 patched 2 0.824
dcc deleted in colorectal carcinoma 0.821
wu:fv91b12 wu:fv91b12 0.821
sox9b SRY-box containing gene 9b 0.820
rx3 retinal homeobox gene 3 0.820
hoxb3a homeo box B3a 0.820
notch1a notch homolog 1a 0.818
isl1 islet1 0.815
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.814
chd chordin 0.812
cxcr4b chemokine (C-X-C motif), receptor 4b 0.810
atoh8 atonal homolog 8 0.807
wnt11r wingless-type MMTV integration site family, member 11, related 0.802
hoxc6a homeo box C6a 0.797
alcamb activated leukocyte cell adhesion molecule b 0.796
fstl1b follistatin-like 1b 0.794
pax6b paired box gene 6b 0.787
cdh5 cadherin 5 0.785
cyp26a1 cytochrome P450, subfamily XXVIA, polypeptide 1 0.781
igfbp3 insulin-like growth factor binding protein 3 0.774
sox32 SRY-box containing gene 32 0.771
nkx2.2a NK2 transcription factor related 2a 0.764
jun jun proto-oncogene 0.761
pax7a paired box gene 7a 0.749
spry4 sprouty (Drosophila) homolog 4 0.747
robo2 roundabout homolog 2 0.746
fgfr4 fibroblast growth factor receptor 4 0.742
robo1 roundabout homolog 1 0.739
vasa vasa homolog 0.738
shha sonic hedgehog a 0.729
fzd7a frizzled homolog 7a 0.726
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.725
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.971
pha-4 Protein PHA-4 0.961
hlh-2 Protein HLH-2 0.947
egl-8 Protein EGL-8 0.790
vab-3 Protein VAB-3 0.781
unc-42 Protein UNC-42 0.750
ten-1 Protein TEN-1 0.735
npp-4 Protein NPP-4 0.697
unc-73 Protein UNC-73 0.682
egl-44 Protein EGL-44 0.677
mep-1 Protein MEP-1 0.661
egl-46 Protein EGL-46 0.650
pry-1 Protein PRY-1 0.643
pbrm-1 Protein PBRM-1 0.640
hlh-1 Protein HLH-1 0.640
npp-1 Protein NPP-1 0.638
elt-6 Protein ELT-6 0.631
lntl-1 Protein LNTL-1 0.604
ceh-20 Protein CEH-20 0.604
hbl-1 Protein HBL-1 0.603
mig-5 Protein MIG-5 0.567
egl-13 Protein EGL-13 0.567
syg-1 Protein SYG-1 0.565
sas-5 Protein SAS-5 0.553
exc-5 Protein EXC-5 0.544
sem-5 Protein SEM-5 0.529
egl-27 Protein EGL-27 0.524
T28F4.1 Protein T28F4.1 0.518
let-60 Protein LET-60 0.513
inx-3 Protein INX-3 0.512
mat-3 Protein MAT-3 0.503
nhr-67 Protein NHR-67 0.501
mel-28 Protein MEL-28 0.500
CELE_Y41E3.11 Protein Y41E3.11 0.500
eor-2 Protein EOR-2 0.499
fkh-2 Protein FKH-2 0.498
peb-1 Protein PEB-1 0.484
lin-12 Protein LIN-12 0.484
sur-2 Protein SUR-2 0.484
daf-11 Protein DAF-11 0.482
F21A10.2 Protein F21A10.2 0.481
snr-1 Protein SNR-1 0.477
mes-3 Protein MES-3 0.468
pxf-1 Protein PXF-1 0.465
nrde-3 Protein NRDE-3 0.455
C27F2.8 Protein C27F2.8 0.449
atg-2 Protein ATG-2 0.446
hnd-1 Protein HND-1 0.443
R10E12.2 Protein R10E12.2 0.440
daf-12 Protein DAF-12 0.434
bet-2 Protein BET-2 0.425
mys-1 Protein MYS-1 0.423
unc-40 Protein UNC-40 0.421
eat-16 Protein EAT-16 0.407
eor-1 Protein EOR-1 0.406
vav-1 Protein VAV-1 0.398
apx-1 Protein APX-1 0.395
fln-2 Protein FLN-2 0.392
mab-5 Protein MAB-5 0.391
hcp-3 Protein HCP-3 0.390
unc-62 Protein UNC-62 0.383
glp-1 Protein GLP-1 0.382
unc-115 Protein UNC-115 0.381
snr-4 Protein SNR-4 0.379
pac-1 Protein PAC-1 0.377
trr-1 Protein TRR-1 0.374
swan-2 Protein SWAN-2 0.373
ubc-12 Protein UBC-12 0.373
taf-9 Protein TAF-9 0.372
unc-43 Protein UNC-43 0.370
nhr-10 Protein NHR-10 0.368
npp-7 Protein NPP-7 0.366
rsp-5 Protein RSP-5 0.365
mig-2 Protein MIG-2 0.365
imb-2 Protein IMB-2 0.364
nhr-46 Protein NHR-46 0.361
epn-1 Protein EPN-1 0.360
mlk-1 Protein MLK-1 0.360
lmn-1 Protein LMN-1 0.357
dlk-1 Protein DLK-1 0.356
plc-1 Protein PLC-1 0.351
lin-59 Protein LIN-59 0.350
sas-4 Protein SAS-4 0.349
pkg-1 Protein PKG-1 0.349
pqn-62 Protein PQN-62 0.346
sop-2 Protein SOP-2 0.346
cdc-26 Protein CDC-26 0.345
CELE_F19F10.9 Protein F19F10.9 0.345
cam-1 Protein CAM-1 0.345
soc-2 Protein SOC-2 0.345
efa-6 Protein EFA-6 0.342
lsy-2 Protein LSY-2 0.342
let-19 Protein LET-19 0.337
ceh-27 Protein CEH-27 0.334
par-1 Protein PAR-1 0.334
bar-1 Protein BAR-1 0.332
tps-1 Protein TPS-1 0.330
odd-2 Protein ODD-2 0.329
mom-2 Protein MOM-2 0.327
dpy-22 Protein DPY-22 0.325
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Akt1 CG4006 gene product from transcript CG4006-RA 0.999
slmb supernumerary limbs 0.999
G-oalpha47A G protein oalpha 47A 0.999
brat brain tumor 0.998
wg wingless 0.998
lola longitudinals lacking 0.997
CycA Cyclin A 0.993
Mad Mothers against dpp 0.989
ovo CG6824 gene product from transcript CG6824-RE 0.989
ttv tout-velu 0.986
drk downstream of receptor kinase 0.984
shn schnurri 0.984
CaMKII Calcium/calmodulin-dependent protein kinase II 0.983
babo baboon 0.982
put punt 0.981
BicD Bicaudal D 0.976
mnb minibrain 0.975
pbl pebble 0.975
l(2)gl lethal (2) giant larvae 0.973
stan starry night 0.973
ik2 IkappaB kinase-like 2 0.969
robo roundabout 0.969
Appl beta amyloid protein precursor-like 0.968
caz cabeza 0.967
mbc myoblast city 0.966
tsr twinstar 0.964
fru fruitless 0.964
ttk tramtrack 0.963
tgo tango 0.962
htl heartless 0.962
phl pole hole 0.961
abd-A abdominal A 0.960
nmo nemo 0.959
dsh dishevelled 0.959
Ras85D Ras oncogene at 85D 0.953
Sos Son of sevenless 0.953
neuroligin CG13772 gene product from transcript CG13772-RA 0.953
Rac1 CG2248 gene product from transcript CG2248-RA 0.952
pnt pointed 0.945
bowl brother of odd with entrails limited 0.944
LanA Laminin A 0.942
rut rutabaga 0.942
Eps-15 Epidermal growth factor receptor pathway substrate clone 15 0.938
vvl ventral veins lacking 0.937
pros prospero 0.937
shot short stop 0.937
trio CG18214 gene product from transcript CG18214-RA 0.934
nej nejire 0.932
wls wntless 0.930
dos daughter of sevenless 0.927
dnc dunce 0.925
ab abrupt 0.925
TBPH CG10327 gene product from transcript CG10327-RC 0.919
dock dreadlocks 0.918
Dad Daughters against dpp 0.917
pum pumilio 0.916
hep hemipterous 0.915
wdb widerborst 0.914
cta concertina 0.914
neb nebbish 0.912
klu klumpfuss 0.912
Hsp83 Heat shock protein 83 0.909
Mob2 CG11711 gene product from transcript CG11711-RC 0.909
zfh1 Zn finger homeodomain 1 0.908
N Notch 0.907
ft fat 0.905
ena enabled 0.905
jeb jelly belly 0.904
dap dacapo 0.902
Acsl Acyl-CoA synthetase long-chain 0.899
WASp CG1520 gene product from transcript CG1520-RA 0.896
Btk29A Btk family kinase at 29A 0.891
hkb huckebein 0.888
spen split ends 0.886
zip zipper 0.884
shg shotgun 0.883
Egfr Epidermal growth factor receptor 0.883
Ets97D Ets at 97D 0.882
fz2 frizzled 2 0.882
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.880
numb CG3779 gene product from transcript CG3779-RB 0.879
rho rhomboid 0.878
gig gigas 0.876
hts hu li tai shao 0.875
Caki Calcium/calmodulin-dependent protein kinase 0.875
inaD inactivation no afterpotential D 0.874
E(spl) Enhancer of split 0.874
MED6 Mediator complex subunit 6 0.873
cup CG11181 gene product from transcript CG11181-RB 0.869
tkv thickveins 0.869
S6kII RPS6-protein kinase-II 0.867
Atpalpha Na pump alpha subunit 0.867
cutlet CG33122 gene product from transcript CG33122-RA 0.865
Sema-1a CG18405 gene product from transcript CG18405-RD 0.864
foxo forkhead box, sub-group O 0.863
Catsup Catecholamines up 0.859
Kr Kruppel 0.855
Dap160 Dynamin associated protein 160 0.852
ato atonal 0.850
fz frizzled 0.848
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Tgfbr2 transforming growth factor, beta receptor II 0.704
Nlgn2 neuroligin 2 0.666
Rara retinoic acid receptor, alpha 0.657
Fut1 fucosyltransferase 1 0.638
Cd4 Cd4 molecule 0.632
Egr1 early growth response 1 0.621
Calcrl calcitonin receptor-like 0.617
Met met proto-oncogene 0.598
Ifitm3 interferon induced transmembrane protein 3 0.559
Cd9 CD9 molecule 0.556
Vcan versican 0.552
Mmp10 matrix metallopeptidase 10 0.546
Uox urate oxidase 0.536
Fgfr2 fibroblast growth factor receptor 2 0.535
Sirpa signal-regulatory protein alpha 0.533
Sv2a synaptic vesicle glycoprotein 2a 0.528
Jak1 Janus kinase 1 0.523
Itgam integrin, alpha M 0.518
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.516
RGD1564664 similar to LOC387763 protein 0.509
Mmp12 matrix metallopeptidase 12 0.507
Jak2 Janus kinase 2 0.506
Accn2 amiloride-sensitive cation channel 2, neuronal 0.505
Prrx1 paired related homeobox 1 0.498
Bcl2 B-cell CLL/lymphoma 2 0.490
Cebpe CCAAT/enhancer binding protein (C/EBP), epsilon 0.489
Oprd1 opioid receptor, delta 1 0.488
Ptprs protein tyrosine phosphatase, receptor type, S 0.486
Foxs1 forkhead box S1 0.482
Rims1 regulating synaptic membrane exocytosis 1 0.479
Btg2 BTG family, member 2 0.478
Clps colipase, pancreatic 0.476
Neurog3 neurogenin 3 0.474
Adora2a adenosine A2a receptor 0.472
Apol3 apolipoprotein L, 3 0.470
Hspb1 heat shock protein 1 0.467
Robo1 roundabout homolog 1 (Drosophila) 0.466
Mgp matrix Gla protein 0.463
Dnm1 dynamin 1 0.457
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.454
Atp2b3 ATPase, Ca++ transporting, plasma membrane 3 0.448
Gria2 glutamate receptor, ionotropic, AMPA 2 0.446
Junb jun B proto-oncogene 0.445
Hes5 hairy and enhancer of split 5 (Drosophila) 0.444
Fgf5 fibroblast growth factor 5 0.444
Gucy2d guanylate cyclase 2d 0.438
Nfix nuclear factor I/X (CCAAT-binding transcription factor) 0.432
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.427
Foxj1 forkhead box J1 0.424
Galr3 galanin receptor 3 0.424
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.418
Apba1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.416
Slit3 slit homolog 3 (Drosophila) 0.416
Nfia nuclear factor I/A 0.415
Ms4a8a membrane-spanning 4-domains, subfamily A, member 8A 0.401
Pgc progastricsin (pepsinogen C) 0.400
Hes1 hairy and enhancer of split 1 (Drosophila) 0.399
Prap1 proline-rich acidic protein 1 0.397
Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.395
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.394
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.390
Cela2a chymotrypsin-like elastase family, member 2A 0.387
Klf6 Kruppel-like factor 6 0.387
Notch1 Notch homolog 1, translocation-associated (Drosophila) 0.386
Sfrp4 secreted frizzled-related protein 4 0.385
S100a6 S100 calcium binding protein A6 0.384
App amyloid beta (A4) precursor protein 0.383
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.380
Dusp1 dual specificity phosphatase 1 0.378
Musk muscle, skeletal, receptor tyrosine kinase 0.377
Gja1 gap junction protein, alpha 1 0.375
Id3 inhibitor of DNA binding 3 0.374
Tcfe2a transcription factor E2a 0.373
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.372
Hck hemopoietic cell kinase 0.366
Mpeg1 macrophage expressed 1 0.365
Oprm1 opioid receptor, mu 1 0.365
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.365
Cugbp2 CUG triplet repeat, RNA binding protein 2 0.362
Sept8 septin 8 0.360
Acvr1 activin A receptor, type I 0.358
Pecam1 platelet/endothelial cell adhesion molecule 1 0.355
Crygd crystallin, gamma D 0.349
Agtr1a angiotensin II receptor, type 1a 0.348
Lphn2 latrophilin 2 0.347
Cd200r1 CD200 receptor 1 0.344
Cfp complement factor properdin 0.342
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.341
Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase 0.341
Homer3 homer homolog 3 (Drosophila) 0.339
Sycn syncollin 0.338
Stxbp1 syntaxin binding protein 1 0.334
Map3k3 mitogen activated protein kinase kinase kinase 3 0.332
Dnase1l3 deoxyribonuclease 1-like 3 0.331
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.331
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.330
Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 0.330
Mgat3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 0.326
Opn1mw opsin 1 (cone pigments), medium-wave-sensitive 0.325
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.325
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism