The network for 'otic vesicle morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

otic vesicle morphogenesis

The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.

Danio rerio
Name Description Probability Func Analog Organism
fgf3 fibroblast growth factor 3 1.000
bmp2b bone morphogenetic protein 2b 0.996
bmp4 bone morphogenetic protein 4 0.994
dlx4b distal-less homeobox gene 4b 0.993
foxi1 forkhead box I1 0.992
eya1 eyes absent homolog 1 0.990
msxc muscle segment homeobox C 0.979
flh floating head 0.967
dlx3b distal-less homeobox gene 3b 0.963
six4b sine oculis homeobox homolog 4b 0.953
osr1 odd-skipped related 1 (Drosophila) 0.934
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.931
tbx1 T-box 1 0.925
gata3 GATA-binding protein 3 0.922
jag2 jagged 2 0.922
fgf17 fibroblast growth factor 17 0.918
dlx2a distal-less homeobox gene 2a 0.910
hand2 heart and neural crest derivatives expressed transcript 2 0.909
tp63 tumor protein p63 0.906
fgf8a fibroblast growth factor 8 a 0.902
gata2a GATA-binding protein 2a 0.889
sox2 SRY-box containing gene 2 0.850
dlx4a distal-less homeobox gene 4a 0.820
fgf4 fibroblast growth factor 4 0.807
jag1b jagged 1b 0.795
atp1a1a.2 ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide 0.761
pax8 paired box gene 8 0.756
wnt4a wingless-type MMTV integration site family, member 4a 0.737
wnt3 wingless-type MMTV integration site family, member 3 0.722
shhb sonic hedgehog b 0.665
igfbp3 insulin-like growth factor binding protein 3 0.636
edn1 endothelin 1 0.627
bmp2a bone morphogenetic protein 2a 0.570
ncs1a neuronal calcium sensor 1a 0.558
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.550
dlx5a distal-less homeobox gene 5a 0.545
twist3 twist3 0.528
fsta follistatin a 0.518
pitx2 paired-like homeodomain transcription factor 2 0.510
pax9 paired box gene 9 0.482
smad1 MAD homolog 1 (Drosophila) 0.481
fgfrl1b fibroblast growth factor receptor-like 1b 0.475
crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.472
hnf1ba HNF1 homeobox Ba 0.463
nkx2.3 NK2 transcription factor related 3 0.462
raraa retinoic acid receptor, alpha a 0.430
dlx2b distal-less homeobox gene 2b 0.426
gbx2 gastrulation brain homeo box 2 0.422
mecom MDS1 and EVI1 complex locus 0.416
hoxb3a homeo box B3a 0.406
sox9a SRY-box containing gene 9a 0.398
atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide 0.384
dlx6a distal-less homeobox gene 6a 0.381
foxg1a forkhead box G1a 0.359
hmx4 H6 family homeobox 4 0.347
dla deltaA 0.335
gcm2 glial cells missing homolog 2 (Drosophila) 0.312
nkx2.5 NK2 transcription factor related 5 0.306
tgfb3 transforming growth factor, beta 3 0.303
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.296
foxj1a forkhead box J1a 0.290
vcanb versican b 0.277
neurod4 neurogenic differentiation 4 0.255
hapln3 hyaluronan and proteoglycan link protein 3 0.254
snai1b snail homolog 1b (Drosophila) 0.253
pax2a paired box gene 2a 0.250
sema3d semaphorin 3d 0.248
sfrp1a secreted frizzled-related protein 1a 0.228
prdm1a PR domain containing 1a, with ZNF domain 0.227
tfap2a transcription factor AP-2 alpha 0.226
gyltl1b glycosyltransferase-like 1b 0.225
cdx4 caudal type homeo box transcription factor 4 0.221
ephb4b eph receptor B4b 0.218
hhip hedgehog interacting protein 0.215
fgf8b fibroblast growth factor 8 b 0.212
six2a sine oculis-related homeobox 2a 0.205
hmx3 homeo box (H6 family) 3 0.203
rxrga retinoid x receptor, gamma a 0.200
tfap2c transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.200
emx3 empty spiracles homeobox 3 0.200
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.199
map2k4a mitogen-activated protein kinase kinase 4a 0.198
gpr126 G protein-coupled receptor 126 0.195
tfec transcription factor EC 0.195
foxa2 forkhead box A2 0.195
crestin crestin 0.192
tfeb transcription factor EB 0.190
sparc secreted acidic cysteine rich glycoprotein 0.180
cdh2 cadherin 2, neuronal 0.179
gbx1 gastrulation brain homeobox 1 0.176
runx2b runt-related transcription factor 2b 0.174
dacha dachshund a 0.174
dlx1a distal-less homeobox gene 1a 0.172
si:ch211-173o4.2 si:ch211-173o4.2 0.167
egr1 early growth response 1 0.167
nrg2a neuregulin 2a 0.165
six4a sine oculis homeobox homolog 4a 0.165
rel v-rel reticuloendotheliosis viral oncogene homolog 0.160
wnt1 wingless-type MMTV integration site family, member 1 0.159
msxd muscle segment homeobox D 0.158
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 0.999
Fgfr2 fibroblast growth factor receptor 2 0.993
Gli3 GLI-Kruppel family member GLI3 0.993
Eya1 eyes absent 1 homolog (Drosophila) 0.986
Fgf10 fibroblast growth factor 10 0.967
Tbx3 T-box 3 0.953
Pitx2 paired-like homeodomain transcription factor 2 0.951
Pax3 paired box gene 3 0.940
Foxg1 forkhead box G1 0.937
Bmp4 bone morphogenetic protein 4 0.914
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.903
Pax2 paired box gene 2 0.903
Otx2 orthodenticle homolog 2 (Drosophila) 0.900
Fgf8 fibroblast growth factor 8 0.894
Ednra endothelin receptor type A 0.786
Gbx2 gastrulation brain homeobox 2 0.750
Prrx1 paired related homeobox 1 0.740
Foxc1 forkhead box C1 0.674
Tbx1 T-box 1 0.648
Nog noggin 0.607
Tcfap2a transcription factor AP-2, alpha 0.597
Sox9 SRY-box containing gene 9 0.592
Sox2 SRY-box containing gene 2 0.567
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.541
Hes1 hairy and enhancer of split 1 (Drosophila) 0.507
Fgfr1 fibroblast growth factor receptor 1 0.493
Pitx1 paired-like homeodomain transcription factor 1 0.486
Hoxa1 homeobox A1 0.485
Dlx5 distal-less homeobox 5 0.471
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.427
Hand2 heart and neural crest derivatives expressed transcript 2 0.404
Chd7 chromodomain helicase DNA binding protein 7 0.379
Hoxd13 homeobox D13 0.366
Chrd chordin 0.330
Foxc2 forkhead box C2 0.327
Lmx1a LIM homeobox transcription factor 1 alpha 0.324
Jag1 jagged 1 0.323
Fgfr3 fibroblast growth factor receptor 3 0.304
Rarg retinoic acid receptor, gamma 0.268
Gata3 GATA binding protein 3 0.251
Gsc goosecoid homeobox 0.250
Rarb retinoic acid receptor, beta 0.227
Sox11 SRY-box containing gene 11 0.225
Hand1 heart and neural crest derivatives expressed transcript 1 0.210
Gli2 GLI-Kruppel family member GLI2 0.206
Twist2 twist homolog 2 (Drosophila) 0.203
Vangl2 vang-like 2 (van gogh, Drosophila) 0.180
Msx1 homeobox, msh-like 1 0.177
Isl1 ISL1 transcription factor, LIM/homeodomain 0.173
Bmp7 bone morphogenetic protein 7 0.158
Msx2 homeobox, msh-like 2 0.150
Tbx15 T-box 15 0.149
Hmx3 H6 homeobox 3 0.148
Hoxa13 homeobox A13 0.129
Fgf3 fibroblast growth factor 3 0.117
Zeb1 zinc finger E-box binding homeobox 1 0.110
Trp63 transformation related protein 63 0.095
Pax9 paired box gene 9 0.089
Nodal nodal 0.086
Foxf1a forkhead box F1a 0.080
Runx2 runt related transcription factor 2 0.078
Wnt3a wingless-related MMTV integration site 3A 0.077
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.076
Pou3f3 POU domain, class 3, transcription factor 3 0.074
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.069
Tgfb2 transforming growth factor, beta 2 0.069
Fgf9 fibroblast growth factor 9 0.066
Hoxa11 homeobox A11 0.066
Alx4 aristaless-like homeobox 4 0.066
Fstl1 follistatin-like 1 0.066
Hoxd11 homeobox D11 0.065
Hesx1 homeobox gene expressed in ES cells 0.065
Meox2 mesenchyme homeobox 2 0.063
Hes5 hairy and enhancer of split 5 (Drosophila) 0.057
Pax6 paired box gene 6 0.055
Tcf21 transcription factor 21 0.055
Sall4 sal-like 4 (Drosophila) 0.054
Nkx2-1 NK2 homeobox 1 0.052
Smad6 MAD homolog 6 (Drosophila) 0.052
Bdnf brain derived neurotrophic factor 0.052
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.052
Lhx3 LIM homeobox protein 3 0.052
Prrx2 paired related homeobox 2 0.050
Emx2 empty spiracles homolog 2 (Drosophila) 0.049
Vegfa vascular endothelial growth factor A 0.047
Btbd17 BTB (POZ) domain containing 17 0.046
Hoxd3 homeobox D3 0.043
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.039
Hoxa3 homeobox A3 0.038
Efnb2 ephrin B2 0.037
Ret ret proto-oncogene 0.036
Tlx3 T-cell leukemia, homeobox 3 0.036
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.035
Smo smoothened homolog (Drosophila) 0.034
Foxh1 forkhead box H1 0.033
Zic3 zinc finger protein of the cerebellum 3 0.033
Lhx1 LIM homeobox protein 1 0.033
She src homology 2 domain-containing transforming protein E 0.033
Phox2b paired-like homeobox 2b 0.032
Hoxb3 homeobox B3 0.032
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ifitm3 interferon induced transmembrane protein 3 0.011
Lgals3bp lectin, galactoside-binding, soluble, 3 binding protein 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism