IMP

Process View

Drosophila melanogaster

13 genes annotated in fly

muscle contraction

A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "muscle contraction"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "muscle contraction" (in gray)

Name	Description	Probability	Func Analog Organism
Mhc	Myosin heavy chain	0.506
wupA	wings up A	0.424	Mouse
Act88F	Actin 88F	0.128
TER94	CG2331 gene product from transcript CG2331-RA	0.120
Itp-r83A	Inositol 1,4,5,-tris-phosphate receptor	0.115	Worm
slo	slowpoke	0.108	Human Mouse
Rya-r44F	Ryanodine receptor 44F	0.100
cpb	capping protein beta	0.100
Caki	Calcium/calmodulin-dependent protein kinase	0.088
sesB	stress-sensitive B	0.079
brp	bruchpilot	0.073
Tm2	Tropomyosin 2	0.072	Human Zebrafish Mouse Rat
tomosyn	CG17762 gene product from transcript CG17762-RB	0.068
Hsp27	Heat shock protein 27	0.060	Rat
pum	pumilio	0.059
Jafrac1	thioredoxin peroxidase 1	0.058
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.058
Octbeta2R	CG33976 gene product from transcript CG33976-RA	0.057
Nrx-1	Neurexin 1	0.057
hts	hu li tai shao	0.055
HLH106	Helix loop helix protein 106	0.055
Irk2	Inwardly rectifying potassium channel 2	0.054	Human Rat
Ca-P60A	Calcium ATPase at 60A	0.052	Human Zebrafish Rat
Rel	Relish	0.051
Hsp26	Heat shock protein 26	0.048	Rat
dys	dysfusion	0.048
hiw	highwire	0.046
RpS3	Ribosomal protein S3	0.046
up	upheld	0.044	Human Zebrafish Mouse Worm
t	tan	0.042
Prm	Paramyosin	0.039
Nmdar1	NMDA receptor 1	0.038
VAChT	CG32848 gene product from transcript CG32848-RA	0.036
stj	straightjacket	0.035
Mlc2	Myosin light chain 2	0.031
Ace	Acetylcholine esterase	0.030
KCNQ	KCNQ potassium channel	0.030
CG42629	CG42629 gene product from transcript CG42629-RB	0.030
TyrR	Tyramine receptor	0.028
Scgdelta	Sarcoglycan delta	0.028
Hsp23	Heat shock protein 23	0.027	Rat
Gad1	Glutamic acid decarboxylase 1	0.026
fng	fringe	0.026
mbc	myoblast city	0.026
Sod2	Superoxide dismutase 2 (Mn)	0.026
rtGEF	rho-type guanine exchange factor	0.026
Rdl	Resistant to dieldrin	0.025
Glut1	Glucose transporter 1	0.025
hig	hikaru genki	0.025
Actn	alpha actinin	0.025	Mouse
Irk3	Inwardly rectifying potassium channel 3	0.024	Human Rat
Act57B	Actin 57B	0.024
mtt	mangetout	0.024
Sh	Shaker	0.024
Cat	Catalase	0.023
Gpdh	Glycerol 3 phosphate dehydrogenase	0.022
Gr28b	Gustatory receptor 28b	0.022
Tom34	Translocase of outer membrane 34	0.022
Pgk	Phosphoglycerate kinase	0.022
Nrg	Neuroglian	0.022
Atg1	Autophagy-specific gene 1	0.022
rho	rhomboid	0.021
Sox15	Sox box protein 15	0.021
dpr5	CG5308 gene product from transcript CG5308-RA	0.021
CG11299	CG11299 gene product from transcript CG11299-RA	0.021
Hsp68	Heat shock protein 68	0.020
Pink1	PTEN-induced putative kinase 1	0.020
acj6	abnormal chemosensory jump 6	0.020
Csp	Cysteine string protein	0.020
Mlp84B	Muscle LIM protein at 84B	0.020	Mouse
trp	transient receptor potential	0.020
GluRIIA	Glutamate receptor IIA	0.020
Zasp66	Z band alternatively spliced PDZ-motif protein 66	0.019
psq	pipsqueak	0.019
BG4	CG12297 gene product from transcript CG12297-RA	0.019
nwk	nervous wreck	0.019
Ant2	Adenine nucleotide translocase 2	0.019
Myd88	CG2078 gene product from transcript CG2078-RA	0.018
Gbeta76C	G protein beta-subunit 76C	0.018
Marf	Mitochondrial assembly regulatory factor	0.018
hipk	homeodomain interacting protein kinase	0.018
CG31665	CG31665 gene product from transcript CG31665-RA	0.018
Roc1b	CG16988 gene product from transcript CG16988-RA	0.018
Cam	Calmodulin	0.017
RanBPM	Ran-binding protein M	0.017
CG34400	CG34400 gene product from transcript CG34400-RD	0.017
CG10750	CG10750 gene product from transcript CG10750-RA	0.017
CG3371	CG3371 gene product from transcript CG3371-RA	0.017
Krn	Keren	0.017
jeb	jelly belly	0.017
Spn77Ba	Serpin 77Ba	0.017
Rim	CG33547 gene product from transcript CG33547-RB	0.016
Cortactin	CG3637 gene product from transcript CG3637-RA	0.016
Pvf2	PDGF- and VEGF-related factor 2	0.016
Dab	Disabled	0.016
Nop60B	Nucleolar protein at 60B	0.016
amon	amontillado	0.016
mys	myospheroid	0.016	Worm
CG15199	CG15199 gene product from transcript CG15199-RA	0.015
dos	daughter of sevenless	0.015
Zasp52	Z band alternatively spliced PDZ-motif protein 52	0.015
cpo	couch potato	0.015
gbb	glass bottom boat	0.015
p38b	CG7393 gene product from transcript CG7393-RA	0.014
plx	pollux	0.014
Mf	Myofilin	0.014
mp	multiplexin	0.014
CG9063	CG9063 gene product from transcript CG9063-RA	0.014
Sox102F	CG11153 gene product from transcript CG11153-RB	0.014
zetaTry	zetaTrypsin	0.014
Optix	CG18455 gene product from transcript CG18455-RA	0.013
cher	cheerio	0.013
GstS1	Glutathione S transferase S1	0.013
daw	dawdle	0.013
repo	reversed polarity	0.013
CG14022	CG14022 gene product from transcript CG14022-RA	0.013
endoA	endophilin A	0.013
sals	sarcomere length short	0.013
CG12484	CG12484 gene product from transcript CG12484-RB	0.013
VGlut	Vesicular glutamate transporter	0.012
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.012
CG12239	CG12239 gene product from transcript CG12239-RA	0.012
Frq1	Frequenin 1	0.012
lap	like-AP180	0.012
CG5023	CG5023 gene product from transcript CG5023-RA	0.012
CG1909	CG1909 gene product from transcript CG1909-RA	0.012
kst	karst	0.012
igl	igloo	0.012
achi	achintya	0.012
Sod	Superoxide dismutase	0.012	Mouse
Gr64e	Gustatory receptor 64e	0.012
Act79B	Actin 79B	0.012
Sh3beta	CG8582 gene product from transcript CG8582-RD	0.011
spin	spinster	0.011
sax	saxophone	0.011
Lasp	CG3849 gene product from transcript CG3849-RB	0.011
Akap200	A kinase anchor protein 200	0.011
RpS15Aa	Ribosomal protein S15Aa	0.011
c11.1	CG12132 gene product from transcript CG12132-RA	0.011
ecd	ecdysoneless	0.011
Mlc1	Myosin alkali light chain 1	0.011
Dap160	Dynamin associated protein 160	0.011
egr	eiger	0.011
CG11656	CG11656 gene product from transcript CG11656-RA	0.011
Rtnl1	CG33113 gene product from transcript CG33113-RF	0.011
dome	domeless	0.011
king-tubby	king tubby	0.011
Pect	Phosphoethanolamine cytidylyltransferase	0.011
tna	tonalli	0.011
CG42369	CG42369 gene product from transcript CG42369-RA	0.010
eas	easily shocked	0.010
CG14109	CG14109 gene product from transcript CG14109-RA	0.010
Smr	Smrter	0.010
kermit	CG11546 gene product from transcript CG11546-RB	0.010
jar	jaguar	0.010
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.010
5-HT1A	Serotonin receptor 1A	0.010