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Process View

Drosophila melanogaster

19 genes annotated in fly

reciprocal meiotic recombination

The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "reciprocal meiotic recombination"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "reciprocal meiotic recombination" (in gray)

Name	Description	Probability	Func Analog Organism
spn-A	spindle A	1.000	Yeast
spn-B	spindle B	1.000
mei-9	meiotic 9	1.000
lok	loki	0.989
c(3)G	crossover suppressor on 3 of Gowen	0.961
nod	no distributive disjunction	0.960
zwilch	CG18729 gene product from transcript CG18729-RA	0.960
mus312	mutagen-sensitive 312	0.958
mus301	mutagen-sensitive 301	0.952	Worm
mus101	mutagen-sensitive 101	0.946
spn-D	spindle D	0.944	Mouse
mei-41	meiotic 41	0.941
okr	okra	0.930
RecQ5	homolog of RecQ	0.920
ncd	non-claret disjunctional	0.828
cort	cortex	0.809
Brca2	Breast cancer 2, early onset homolog	0.749
Mcm5	Minichromosome maintenance 5	0.674
mei-218	meiotic 218	0.659
plu	plutonium	0.583
mus205	mutagen-sensitive 205	0.564
CG5524	CG5524 gene product from transcript CG5524-RA	0.509
mei-217	CG33935 gene product from transcript CG33935-RC	0.504
hdm	hold'em	0.466
Mcm3	Minichromosome maintenance 3	0.444
CG11403	CG11403 gene product from transcript CG11403-RA	0.418
sub	subito	0.410
zuc	zucchini	0.405
spn-E	spindle E	0.386
CG7928	CG7928 gene product from transcript CG7928-RA	0.375
mus304	mutagen-sensitive 304	0.373
twe	twine	0.371
Axs	Abnormal X segregation	0.359
CG2662	CG2662 gene product from transcript CG2662-RA	0.349
lds	lodestar	0.335
MAGE	CG10059 gene product from transcript CG10059-RA	0.305
mus201	mutagen-sensitive 201	0.291
CG18271	CG18271 gene product from transcript CG18271-RB	0.284
mei-W68	meiotic W68	0.278
CDC45L	CG3658 gene product from transcript CG3658-RA	0.266
asun	asunder	0.238
trem	trade embargo	0.237
CG11560	CG11560 gene product from transcript CG11560-RA	0.232
CG5199	CG5199 gene product from transcript CG5199-RA	0.229
Cks30A	Cyclin-dependent kinase subunit 30A	0.189
ord	orientation disruptor	0.184
Klp3A	Kinesin-like protein at 3A	0.174
CG2617	CG2617 gene product from transcript CG2617-RA	0.167
DNApol-eta	CG7143 gene product from transcript CG7143-RA	0.164
rad50	CG6339 gene product from transcript CG6339-RD	0.161
CG4424	CG4424 gene product from transcript CG4424-RA	0.158	Fly
Cap-D3	Chromosome associated protein D3	0.156
png	pan gu	0.155
Shc	SHC-adaptor protein	0.154
Grip84	gamma-tubulin ring protein 84	0.135
spn-F	CG12114 gene product from transcript CG12114-RA	0.128
ana2	anastral spindle 2	0.121
CG13367	CG13367 gene product from transcript CG13367-RA	0.111
CG11164	CG11164 gene product from transcript CG11164-RA	0.104
asp	abnormal spindle	0.103
grau	grauzone	0.103
CG11071	CG11071 gene product from transcript CG11071-RA	0.088
mei-P22	meiotic P22	0.085
Ercc1	CG10215 gene product from transcript CG10215-RA	0.082
cutlet	CG33122 gene product from transcript CG33122-RA	0.082	Mouse
mei-S332	meiotic from via Salaria 332	0.075
DNApol-alpha60	DNA polymerase alpha 60kD	0.074
CG14561	CG14561 gene product from transcript CG14561-RA	0.070
alph	alphabet	0.065
l(2)05714	lethal (2) 05714	0.062
Caf1-105	CG12892 gene product from transcript CG12892-RA	0.060
armi	armitage	0.056
CG2712	CG2712 gene product from transcript CG2712-RA	0.056
CG10336	CG10336 gene product from transcript CG10336-RC	0.055
CG8079	CG8079 gene product from transcript CG8079-RA	0.053
prod	proliferation disrupter	0.053
CG17361	CG17361 gene product from transcript CG17361-RA	0.049
CG17802	CG17802 gene product from transcript CG17802-RA	0.049
CG7239	CG7239 gene product from transcript CG7239-RA	0.048
CG7053	CG7053 gene product from transcript CG7053-RA	0.045
ranshi	CG9793 gene product from transcript CG9793-RA	0.045
mus308	mutagen-sensitive 308	0.043
CG14220	CG14220 gene product from transcript CG14220-RA	0.042
CG7183	CG7183 gene product from transcript CG7183-RA	0.041
nudE	CG8104 gene product from transcript CG8104-RB	0.040
can	cannonball	0.040
Smc5	CG32438 gene product from transcript CG32438-RE	0.039
c(2)M	crossover suppressor on 2 of Manheim	0.037
CG8478	CG8478 gene product from transcript CG8478-RD	0.036
CG15601	CG15601 gene product from transcript CG15601-RA	0.036
orb	oo18 RNA-binding protein	0.035
fs(1)Ya	female sterile (1) Young arrest	0.035
CycC	Cyclin C	0.034
dah	discontinuous actin hexagon	0.034
CG7824	CG7824 gene product from transcript CG7824-RC	0.033
gammaTub37C	gamma-Tubulin at 37C	0.032
az2	CG1605 gene product from transcript CG1605-RA	0.032
Mcm7	Minichromosome maintenance 7	0.031
CG7745	CG7745 gene product from transcript CG7745-RA	0.031
CG16734	CG16734 gene product from transcript CG16734-RD	0.031
CG14667	CG14667 gene product from transcript CG14667-RA	0.030
rasp	CG11495 gene product from transcript CG11495-RA	0.030
cuff	cutoff	0.029
Orc4	Origin recognition complex subunit 4	0.029
pie	pineapple eye	0.029
SA-2	Stromalin-2	0.029
phr	photorepair	0.029
CG10324	CG10324 gene product from transcript CG10324-RA	0.028
mus309	mutagen-sensitive 309	0.028
HP5	Heterochromatin protein 5	0.027
aly	always early	0.027
WDR79	WD repeat domain 79 homolog	0.026
AGO3	Argonaute 3	0.026
DMAP1	CG11132 gene product from transcript CG11132-RA	0.026
CG4854	CG4854 gene product from transcript CG4854-RA	0.025	Fly
Gsc	Goosecoid	0.025
CG7795	CG7795 gene product from transcript CG7795-RD	0.023
CG13322	CG13322 gene product from transcript CG13322-RA	0.023
gnu	giant nuclei	0.022
Sas-4	CG10061 gene product from transcript CG10061-RA	0.022
CG14965	CG14965 gene product from transcript CG14965-RA	0.022
CG15436	CG15436 gene product from transcript CG15436-RA	0.022
DNApol-delta	DNA-polymerase-delta	0.022
CG12253	CG12253 gene product from transcript CG12253-RA	0.022
CG4496	CG4496 gene product from transcript CG4496-RA	0.022
X11L	CG5675 gene product from transcript CG5675-RB	0.022
CG14303	CG14303 gene product from transcript CG14303-RA	0.021
CG14711	CG14711 gene product from transcript CG14711-RA	0.021	Fly
CG8569	CG8569 gene product from transcript CG8569-RA	0.020
CG1602	CG1602 gene product from transcript CG1602-RA	0.020
CG16863	CG16863 gene product from transcript CG16863-RA	0.019
CG11906	CG11906 gene product from transcript CG11906-RA	0.019
Es2	CG1474 gene product from transcript CG1474-RA	0.019
CG31251	CG31251 gene product from transcript CG31251-RA	0.019
Taf7	TBP-associated factor 7	0.019
Rev1	CG12189 gene product from transcript CG12189-RA	0.019
CG3032	CG3032 gene product from transcript CG3032-RA	0.018
CG14814	CG14814 gene product from transcript CG14814-RA	0.018
mei-38	meiotic 38	0.018
CG12717	CG12717 gene product from transcript CG12717-RA	0.018
xmas-1	CG32561 gene product from transcript CG32561-RA	0.017
Dsor1	Downstream of raf1	0.017
CG1663	CG1663 gene product from transcript CG1663-RA	0.017
CG6808	CG6808 gene product from transcript CG6808-RA	0.017	Fly
CG3975	CG3975 gene product from transcript CG3975-RA	0.016
CG6685	CG6685 gene product from transcript CG6685-RA	0.016
Mcm6	Minichromosome maintenance 6	0.016
tefu	telomere fusion	0.016
CG7341	CG7341 gene product from transcript CG7341-RB	0.016
CG10366	CG10366 gene product from transcript CG10366-RA	0.016
CG14074	CG14074 gene product from transcript CG14074-RA	0.016
CG8950	CG8950 gene product from transcript CG8950-RA	0.016
NiPp1	Nuclear inhibitor of Protein phosphatase 1	0.016
CG5877	CG5877 gene product from transcript CG5877-RA	0.016
BubR1	Bub1-related kinase	0.015
CG17806	CG17806 gene product from transcript CG17806-RA	0.015
CG4622	CG4622 gene product from transcript CG4622-RC	0.015
Ptp61F	Protein tyrosine phosphatase 61F	0.015
CG14102	CG14102 gene product from transcript CG14102-RA	0.015
CG17446	CG17446 gene product from transcript CG17446-RB	0.015
CG6927	CG6927 gene product from transcript CG6927-RA	0.014
Oseg6	CG11237 gene product from transcript CG11237-RA	0.014
CG42360	CG42360 gene product from transcript CG42360-RA	0.014
Tsp39D	Tetraspanin 39D	0.014
CG18262	CG18262 gene product from transcript CG18262-RA	0.014
CG17568	CG17568 gene product from transcript CG17568-RA	0.014
CG4813	CG4813 gene product from transcript CG4813-RA	0.014
lkb1	CG9374 gene product from transcript CG9374-RJ	0.014
Cp36	Chorion protein 36	0.014
Klp67A	Kinesin-like protein at 67A	0.013
CG14962	CG14962 gene product from transcript CG14962-RA	0.013
Oseg1	CG7161 gene product from transcript CG7161-RA	0.013
sofe	sister of feo	0.013
CG12010	CG12010 gene product from transcript CG12010-RA	0.013
CG7713	CG7713 gene product from transcript CG7713-RA	0.013
Fen1	Flap endonuclease 1	0.013
CG2129	CG2129 gene product from transcript CG2129-RA	0.013
CG5924	CG5924 gene product from transcript CG5924-RA	0.013
CG15914	CG15914 gene product from transcript CG15914-RA	0.013
Tgt	tRNA-guanine transglycosylase	0.013
CG3326	CG3326 gene product from transcript CG3326-RA	0.012
omd	oocyte maintenance defects	0.012
Bgb	Big brother	0.012
CG4788	CG4788 gene product from transcript CG4788-RA	0.012
CG6843	CG6843 gene product from transcript CG6843-RA	0.012
CG6683	CG6683 gene product from transcript CG6683-RA	0.012
RecQ4	CG7487 gene product from transcript CG7487-RA	0.012
Grip128	CG9201 gene product from transcript CG9201-RB	0.012
CG42554	CG42554 gene product from transcript CG42554-RA	0.012
CG9948	CG9948 gene product from transcript CG9948-RA	0.011
Nipped-B	CG17704 gene product from transcript CG17704-RI	0.011
dwg	deformed wings	0.011
CG8301	CG8301 gene product from transcript CG8301-RA	0.011
CG10722	CG10722 gene product from transcript CG10722-RA	0.011
achi	achintya	0.011
FLASH	FLASH ortholog	0.011
CG4294	CG4294 gene product from transcript CG4294-RB	0.011
NELF-B	CG32721 gene product from transcript CG32721-RA	0.011
CG31875	CG31875 gene product from transcript CG31875-RC	0.011
CG10209	CG10209 gene product from transcript CG10209-RA	0.011
wisp	wispy	0.010
Vps16B	Vacuolar protein sorting 16B	0.010
CG17328	CG17328 gene product from transcript CG17328-RA	0.010
Top3alpha	Topoisomerase 3alpha	0.010
A16	CG9933 gene product from transcript CG9933-RA	0.010
Smg6	CG6369 gene product from transcript CG6369-RA	0.010