IMP

Process View

Drosophila melanogaster

14 genes annotated in fly

cellular response to reactive oxygen species

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in fly Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to reactive oxygen species"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to reactive oxygen species" (in gray)

Name	Description	Probability	Func Analog Organism
Sod	Superoxide dismutase	0.991
Rac1	CG2248 gene product from transcript CG2248-RA	0.844
Prx5	Peroxiredoxin 5	0.694	Human
Trx-2	thioredoxin-2	0.651
PHGPx	CG12013 gene product from transcript CG12013-RC	0.644
p38b	CG7393 gene product from transcript CG7393-RA	0.547
Mpk2	CG5475 gene product from transcript CG5475-RB	0.317
cindr	CIN85 and CD2AP orthologue	0.308
wupA	wings up A	0.258
MTF-1	Metal response element-binding Transcription Factor-1	0.255
Prx2540-2	Peroxiredoxin 2540	0.222
Thor	CG8846 gene product from transcript CG8846-RA	0.219
Pgk	Phosphoglycerate kinase	0.179
Aldh	Aldehyde dehydrogenase	0.160
chico	CG5686 gene product from transcript CG5686-RB	0.160
Jra	Jun-related antigen	0.141
CG6783	CG6783 gene product from transcript CG6783-RC	0.137
Pvr	PDGF- and VEGF-receptor related	0.136
SdhB	Succinate dehydrogenase B	0.121
klar	klarsicht	0.118
Cat	Catalase	0.111	Yeast Mouse
Pgam5	Phosphoglycerate mutase 5	0.109
CG6543	CG6543 gene product from transcript CG6543-RA	0.106
Mekk1	CG7717 gene product from transcript CG7717-RB	0.101
Df31	Decondensation factor 31	0.098
TwdlE	TweedleE	0.097
Tpi	Triose phosphate isomerase	0.093
Ric	Ras which interacts with Calmodulin	0.092
CG4390	CG4390 gene product from transcript CG4390-RB	0.088
Myo31DF	Myosin 31DF	0.087
NLaz	Neural Lazarillo	0.078
rl	rolled	0.076
up	upheld	0.067
ena	enabled	0.066
GLaz	Glial Lazarillo	0.062
CG13319	CG13319 gene product from transcript CG13319-RA	0.061
CG8709	CG8709 gene product from transcript CG8709-RK	0.058
p53	CG33336 gene product from transcript CG33336-RB	0.058
CG14715	CG14715 gene product from transcript CG14715-RA	0.057
CG12001	CG12001 gene product from transcript CG12001-RA	0.056
Trim9	CG31721 gene product from transcript CG31721-RB	0.053
janA	janus A	0.051
Trap1	CG3152 gene product from transcript CG3152-RA	0.050
CG7998	CG7998 gene product from transcript CG7998-RA	0.044
park	parkin	0.044
Zasp52	Z band alternatively spliced PDZ-motif protein 52	0.042
Atf-2	Activating transcription factor-2	0.041
gpp	grappa	0.041
awd	abnormal wing discs	0.040
CG30410	CG30410 gene product from transcript CG30410-RB	0.039
Fatp	Fatty acid (long chain) transport protein	0.039
Vps4	Vacuolar protein sorting 4	0.038
puc	puckered	0.038
Gga	CG3002 gene product from transcript CG3002-RB	0.036
DJ-1alpha	CG6646 gene product from transcript CG6646-RA	0.036
Rya-r44F	Ryanodine receptor 44F	0.035
fzy	fizzy	0.035
fh	frataxin homolog	0.033
kibra	kibra ortholog	0.032
InR	Insulin-like receptor	0.032
rin	rasputin	0.032
regucalcin	CG1803 gene product from transcript CG1803-RA	0.032
IP3K2	Inositol 1,4,5-triphosphate kinase 2	0.031
Zw	Zwischenferment	0.030
Rel	Relish	0.029
dys	dysfusion	0.029
CG6429	CG6429 gene product from transcript CG6429-RA	0.029
Khc-73	Kinesin-73	0.027
scny	scrawny	0.026
svp	seven up	0.025
CG9510	CG9510 gene product from transcript CG9510-RC	0.024
XNP	CG4548 gene product from transcript CG4548-RA	0.024
AnnX	Annexin X	0.024
Fkbp13	CG9847 gene product from transcript CG9847-RC	0.023
dj-1beta	CG1349 gene product from transcript CG1349-RA	0.022
Hsp68	Heat shock protein 68	0.022
kermit	CG11546 gene product from transcript CG11546-RB	0.021
Dsor1	Downstream of raf1	0.021
ash1	absent, small, or homeotic discs 1	0.021
imd	immune deficiency	0.020
dnr1	defense repressor 1	0.020
Cyp12d1-p	CG30489 gene product from transcript CG30489-RA	0.020
Cdc42	CG12530 gene product from transcript CG12530-RA	0.020
LamC	Lamin C	0.020
CG42813	CG42813 gene product from transcript CG42813-RA	0.019
CG6673	CG6673 gene product from transcript CG6673-RA	0.019
Tsp42Ef	Tetraspanin 42Ef	0.019
trpml	transient receptor potential mucolipin	0.018
Marf	Mitochondrial assembly regulatory factor	0.018
Prx2540-1	Peroxiredoxin 2540	0.018
CG12171	CG12171 gene product from transcript CG12171-RA	0.018
l(3)82Fd	CG32464 gene product from transcript CG32464-RR	0.018
Pink1	PTEN-induced putative kinase 1	0.018	Human
SuUR	Suppressor of Under-Replication	0.017
CG6576	CG6576 gene product from transcript CG6576-RA	0.017
Mt2	Methyltransferase 2	0.017
CG11033	CG11033 gene product from transcript CG11033-RB	0.017
Pepck	Phosphoenolpyruvate carboxykinase	0.017
slpr	slipper	0.017
SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	0.016
kl-5	male fertility factor kl5	0.016
sun	stunted	0.016
Ald	Aldolase	0.016
CG2862	CG2862 gene product from transcript CG2862-RA	0.016
Sod2	Superoxide dismutase 2 (Mn)	0.015	Mouse Worm
CG8446	CG8446 gene product from transcript CG8446-RC	0.015
Tsp42Ed	Tetraspanin 42Ed	0.015
CG13890	CG13890 gene product from transcript CG13890-RA	0.015
GluRIIA	Glutamate receptor IIA	0.015
Parg	Poly(ADP-ribose) glycohydrolase	0.014
Mkp3	Mitogen-activated protein kinase phosphatase 3	0.014
cyp33	cyclophilin-33	0.013
lea	leak	0.013
alph	alphabet	0.013
mip130	Myb-interacting protein 130	0.013
Eip71CD	Ecdysone-induced protein 28/29kD	0.013
Pcmt	Protein-L-isoaspartate (D-aspartate) O-methyltransferase	0.013
mth	methuselah	0.012
CG12753	CG12753 gene product from transcript CG12753-RB	0.012
Cyp6g1	CG8453 gene product from transcript CG8453-RA	0.012
mRpL44	mitochondrial ribosomal protein L44	0.012
Hnf4	Hepatocyte nuclear factor 4	0.012
CG15611	CG15611 gene product from transcript CG15611-RB	0.012
Rab30	CG9100 gene product from transcript CG9100-RB	0.012
Ser7	CG2045 gene product from transcript CG2045-RA	0.011
CG10103	CG10103 gene product from transcript CG10103-RA	0.011
CG11486	CG11486 gene product from transcript CG11486-RG	0.011
RanBPM	Ran-binding protein M	0.011
Crc	Calreticulin	0.011
TFAM	mitochondrial transcription factor A	0.011
nAcRbeta-21C	nicotinic acetylcholine receptor beta 21C	0.011
Ppt1	Palmitoyl-protein thioesterase 1	0.011
Spn27A	Serpin 27A	0.010
Fhos	CG42610 gene product from transcript CG42610-RC	0.010
e(y)3	enhancer of yellow 3	0.010
CG18522	CG18522 gene product from transcript CG18522-RA	0.010
CG3563	CG3563 gene product from transcript CG3563-RA	0.010
CG8790	CG8790 gene product from transcript CG8790-RB	0.010
cln3	CG5582 gene product from transcript CG5582-RA	0.010