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Process View

Drosophila melanogaster

28 genes annotated in fly

metaphase anaphase transition of mitotic cell cycle

The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "metaphase anaphase transition of mitotic cell cycle"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "metaphase anaphase transition of mitotic cell cycle" (in gray)

Name	Description	Probability	Func Analog Organism
Dref	DNA replication-related element factor	0.438
Cdc37	CG12019 gene product from transcript CG12019-RA	0.382
ncd	non-claret disjunctional	0.364
BubR1	Bub1-related kinase	0.337
CycB	Cyclin B	0.310
cmet	CENP-meta	0.276
CycB3	Cyclin B3	0.222	Worm
Klp61F	Kinesin-like protein at 61F	0.204
Mcm10	Sensitized chromosome inheritance modifier 19	0.200
dup	double parked	0.196
Iswi	Imitation SWI	0.195
CycA	Cyclin A	0.179
gwl	greatwall	0.175
ida	imaginal discs arrested	0.164
tefu	telomere fusion	0.150	Human
fzy	fizzy	0.129
stg	string	0.119
Cenp-C	CG31258 gene product from transcript CG31258-RA	0.114
mars	CG17064 gene product from transcript CG17064-RB	0.114
Pp1-87B	Protein phosphatase 1 at 87B	0.099	Yeast
Sse	Separase	0.096
asp	abnormal spindle	0.095
pav	pavarotti	0.088
cid	centromere identifier	0.087
Cap-G	CG34438 gene product from transcript CG34438-RF	0.086
Rpd3	CG7471 gene product from transcript CG7471-RA	0.083
pie	pineapple eye	0.075
SMC2	CG10212 gene product from transcript CG10212-RA	0.074
RanGap	Ran GTPase activating protein	0.074
Orc2	Origin recognition complex subunit 2	0.068
polo	CG12306 gene product from transcript CG12306-RA	0.065	Human
cnn	centrosomin	0.065
nod	no distributive disjunction	0.063
thr	three rows	0.063
cav	caravaggio	0.062
hpo	hippo	0.056
pim	pimples	0.055
Kmn1	kinetochore Mis12-Ndc80 network component 1	0.055
shtd	shattered	0.054	Worm
Myb	Myb oncogene-like	0.052
Incenp	Inner centromere protein	0.051
borr	borealin-related	0.051
cdc16	CG6759 gene product from transcript CG6759-RA	0.050
ball	ballchen	0.049
Klp3A	Kinesin-like protein at 3A	0.049
SAK	Sak kinase	0.047
nbs	CG6754 gene product from transcript CG6754-RC	0.046
Spc105R	Spc105-related	0.046
larp	La related protein	0.046
kuk	kugelkern	0.045
Nuf2	CG8902 gene product from transcript CG8902-RA	0.043
msps	mini spindles	0.043
DNApol-alpha60	DNA polymerase alpha 60kD	0.042
CG9772	CG9772 gene product from transcript CG9772-RB	0.040
sle	slender lobes	0.040
cdc2	CG5363 gene product from transcript CG5363-RA	0.039
tum	tumbleweed	0.038
Cks30A	Cyclin-dependent kinase subunit 30A	0.038
CG7288	CG7288 gene product from transcript CG7288-RA	0.037
gammaTub37C	gamma-Tubulin at 37C	0.037
Cdc27	CG8610 gene product from transcript CG8610-RA	0.036	Human Worm
Su(H)	Suppressor of Hairless	0.035
brat	brain tumor	0.033
geminin	CG3183 gene product from transcript CG3183-RA	0.033
vtd	verthandi	0.032
asl	asterless	0.032
dap	dacapo	0.032
cdc23	CG2508 gene product from transcript CG2508-RA	0.031
Ndc80	CG9938 gene product from transcript CG9938-RA	0.030
Bj1	Bj1 protein	0.030
Det	Deterin	0.029
Klp10A	CG1453 gene product from transcript CG1453-RA	0.029
DNApol-alpha180	DNA polymerase alpha 180kD	0.028
Cks85A	Cyclin-dependent kinase subunit 85A	0.028
CycE	Cyclin E	0.027
gish	gilgamesh	0.027
mus304	mutagen-sensitive 304	0.026
flfl	falafel	0.024
mus101	mutagen-sensitive 101	0.024
dpa	disc proliferation abnormal	0.024
SMC1	CG6057 gene product from transcript CG6057-RA	0.024
Nek2	CG17256 gene product from transcript CG17256-RA	0.023
alphaTub67C	alpha-Tubulin at 67C	0.023
mus301	mutagen-sensitive 301	0.023
nej	nejire	0.022
mei-S332	meiotic from via Salaria 332	0.022
zwilch	CG18729 gene product from transcript CG18729-RA	0.021
rux	roughex	0.021
barr	barren	0.020
pita	CG3941 gene product from transcript CG3941-RA	0.020
pbl	pebble	0.020
dm	diminutive	0.020
CG4680	CG4680 gene product from transcript CG4680-RA	0.020
plu	plutonium	0.019
Klp67A	Kinesin-like protein at 67A	0.019
Acf1	ATP-dependent chromatin assembly factor large subunit	0.019
ttv	tout-velu	0.018
brm	brahma	0.018
rad50	CG6339 gene product from transcript CG6339-RD	0.018
cp309	CG33957 gene product from transcript CG33957-RB	0.018
CG2617	CG2617 gene product from transcript CG2617-RA	0.018
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.018
wisp	wispy	0.018
chb	chromosome bows	0.018
rod	rough deal	0.018
gammaTub23C	gamma-Tubulin at 23C	0.018
CG13089	CG13089 gene product from transcript CG13089-RA	0.018
msb1l	CG10364 gene product from transcript CG10364-RA	0.018
lds	lodestar	0.017
spn-D	spindle D	0.017
png	pan gu	0.017
hyd	hyperplastic discs	0.017
dhd	deadhead	0.017
pUf68	poly U binding factor 68kD	0.017
enok	enoki mushroom	0.017
Uch-L3	Ubiquitin C-terminal hydrolase	0.016
iHog	interference Hedgehog	0.016
Grip75	CG6176 gene product from transcript CG6176-RA	0.016
Trf4-1	CG11265 gene product from transcript CG11265-RE	0.016
jub	Ajuba LIM protein	0.016
NiPp1	Nuclear inhibitor of Protein phosphatase 1	0.016
KP78b	CG17216 gene product from transcript CG17216-RB	0.015
Sep2	Septin-2	0.015
CG6439	CG6439 gene product from transcript CG6439-RA	0.015
swa	swallow	0.015
Orc5	Origin recognition complex subunit 5	0.015
CG6425	CG6425 gene product from transcript CG6425-RA	0.015
Psf2	CG18013 gene product from transcript CG18013-RA	0.014
TfIIS	RNA polymerase II elongation factor	0.014
Rbf	Retinoblastoma-family protein	0.014
Fcp1	CG12252 gene product from transcript CG12252-RA	0.014
Grip163	CG5688 gene product from transcript CG5688-RA	0.014
CG13625	CG13625 gene product from transcript CG13625-RA	0.014
CG13742	CG13742 gene product from transcript CG13742-RB	0.013
Dcr-1	Dicer-1	0.013
east	enhanced adult sensory threshold	0.013
Mcm7	Minichromosome maintenance 7	0.013
qua	quail	0.013
dah	discontinuous actin hexagon	0.013
Mcm2	Minichromosome maintenance 2	0.013
Krn	Keren	0.013
Mis12	CG18156 gene product from transcript CG18156-RA	0.013
prod	proliferation disrupter	0.013
Uba2	Smt3 activating enzyme 2	0.013
Orc6	Origin recognition complex subunit 6	0.013
mei-38	meiotic 38	0.012
Bap55	Brahma associated protein 55kD	0.012
DNApol-alpha50	DNA polymerase alpha 50kD	0.012
CG10722	CG10722 gene product from transcript CG10722-RA	0.012
betaTub56D	beta-Tubulin at 56D	0.012
NELF-B	CG32721 gene product from transcript CG32721-RA	0.012
c(3)G	crossover suppressor on 3 of Gowen	0.012
Cul-5	Cullin-5	0.011
mi	minus	0.011
scra	scraps	0.011
dock	dreadlocks	0.011
CG10631	CG10631 gene product from transcript CG10631-RA	0.011
Cyp18a1	Cytochrome P450-18a1	0.011
Mcm5	Minichromosome maintenance 5	0.011
CG9986	CG9986 gene product from transcript CG9986-RA	0.011
orb	oo18 RNA-binding protein	0.011
CG6962	CG6962 gene product from transcript CG6962-RA	0.011
mus312	mutagen-sensitive 312	0.011
mei-41	meiotic 41	0.011
Z600	CG17962 gene product from transcript CG17962-RA	0.011
mus209	mutagen-sensitive 209	0.011
E(z)	Enhancer of zeste	0.011
Rel	Relish	0.011
Xpd	Xeroderma pigmentosum D	0.011
cort	cortex	0.011
CG13349	CG13349 gene product from transcript CG13349-RA	0.010
Taspase1	Taspase 1	0.010
CG42251	CG42251 gene product from transcript CG42251-RC	0.010
Aos1	CG12276 gene product from transcript CG12276-RA	0.010
DNApol-delta	DNA-polymerase-delta	0.010
Rpt3	CG16916 gene product from transcript CG16916-RA	0.010
Su(var)2-10	Suppressor of variegation 2-10	0.010
CG31650	CG31650 gene product from transcript CG31650-RF	0.010
nxf2	nuclear RNA export factor 2	0.010
Grip84	gamma-tubulin ring protein 84	0.010
pr-set7	CG3307 gene product from transcript CG3307-RC	0.010
CG1647	CG1647 gene product from transcript CG1647-RA	0.010
CG11071	CG11071 gene product from transcript CG11071-RA	0.010
pex1	peroxin 1	0.010
Sgt1	CG9617 gene product from transcript CG9617-RA	0.010