IMP

Process View

Drosophila melanogaster

15 genes annotated in fly

positive regulation of synaptic transmission

Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of synaptic transmission"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of synaptic transmission" (in gray)

Name	Description	Probability	Func Analog Organism
GluRIIA	Glutamate receptor IIA	0.976
brp	bruchpilot	0.771
Nrx-1	Neurexin 1	0.613
Ank2	Ankyrin 2	0.508
neuroligin	CG13772 gene product from transcript CG13772-RA	0.389	Mouse Rat
unc-104	CG8566 gene product from transcript CG8566-RB	0.361
nwk	nervous wreck	0.350
hiw	highwire	0.291
eag	ether a go-go	0.195
Nmdar1	NMDA receptor 1	0.195
dnc	dunce	0.191
fd85E	forkhead domain 85E	0.180
CG42629	CG42629 gene product from transcript CG42629-RB	0.167
KaiRIA	CG18039 gene product from transcript CG18039-RA	0.162	Fly
jeb	jelly belly	0.158
stnA	stoned A	0.156
Syx1A	Syntaxin 1A	0.153	Mouse Rat
dlg1	discs large 1	0.123	Rat
stnB	stoned B	0.118
CG32635	CG32635 gene product from transcript CG32635-RA	0.113
cac	cacophony	0.098	Rat
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.098	Rat
Syt1	Synaptotagmin 1	0.096	Mouse
stj	straightjacket	0.094
VGlut	Vesicular glutamate transporter	0.087
CG13253	CG13253 gene product from transcript CG13253-RB	0.083
rtGEF	rho-type guanine exchange factor	0.081
dys	dysfusion	0.074
Frq1	Frequenin 1	0.069
AdoR	Adenosine receptor	0.066
Frq2	Frequenin 2	0.060
kdn	knockdown	0.057
Snap	Soluble NSF attachment protein	0.056
Octbeta2R	CG33976 gene product from transcript CG33976-RA	0.053	Rat
fusl	fuseless	0.052
Dap160	Dynamin associated protein 160	0.051
GluRIIE	Glutamate receptor IIE	0.051	Fly
GluRIIB	Glutamate receptor IIB	0.050
CG11317	CG11317 gene product from transcript CG11317-RA	0.050
para	paralytic	0.049
Gad1	Glutamic acid decarboxylase 1	0.048
Snap25	Synapse protein 25	0.044	Mouse
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.044
wit	wishful thinking	0.043
unc-13	CG2999 gene product from transcript CG2999-RA	0.043	Mouse Rat
Pka-R1	cAMP-dependent protein kinase R1	0.043
so	sine oculis	0.042
mtg	mind the gap	0.040
n-syb	n-synaptobrevin	0.039
CG43073	CG43073 gene product from transcript CG43073-RF	0.037
Smg1	CG32743 gene product from transcript CG32743-RA	0.036
Dab	Disabled	0.036
Grip	Glutamate receptor binding protein	0.036
CdsA	CDP diglyceride synthetase	0.034
cpo	couch potato	0.034
CCKLR-17D1	CCK-like receptor at 17D1	0.033
myoglianin	CG1838 gene product from transcript CG1838-RD	0.032
rut	rutabaga	0.031
hdc	headcase	0.030
Bsg	Basigin	0.030
SoxN	SoxNeuro	0.029
cpx	complexin	0.028
mtt	mangetout	0.028
sev	sevenless	0.028
TyrR	Tyramine receptor	0.028
PIP5K59B	CG3682 gene product from transcript CG3682-RE	0.027
CG10260	CG10260 gene product from transcript CG10260-RB	0.026
GluRIIC	Glutamate receptor IIC	0.026	Fly
onecut	CG1922 gene product from transcript CG1922-RA	0.025
Actbeta	Activin-beta	0.025
Rab3	Rab-protein 3	0.024
CG34139	CG34139 gene product from transcript CG34139-RD	0.024	Rat
gl	glass	0.023
Rim	CG33547 gene product from transcript CG33547-RB	0.023
Nrt	Neurotactin	0.023
CanA1	Calcineurin A1	0.022
Khc-73	Kinesin-73	0.022
Mpk2	CG5475 gene product from transcript CG5475-RB	0.021
elav	embryonic lethal abnormal vision	0.021
CG31146	CG31146 gene product from transcript CG31146-RD	0.021	Rat
CG9339	CG9339 gene product from transcript CG9339-RG	0.021
Ric	Ras which interacts with Calmodulin	0.021
simj	simjang	0.021
VAChT	CG32848 gene product from transcript CG32848-RA	0.020
Caki	Calcium/calmodulin-dependent protein kinase	0.019
Amph	Amphiphysin	0.017
stmA	stambha A	0.017
HDAC6	CG6170 gene product from transcript CG6170-RA	0.017
rec	recombination-defective	0.017
Nf1	Neurofibromin 1	0.017
l(2)k16918	lethal (2) k16918	0.017
shi	shibire	0.017
Vmat	Vesicular monoamine transporter	0.017
ewg	erect wing	0.017
Dsk	Drosulfakinin	0.017
Jra	Jun-related antigen	0.016
dimm	dimmed	0.015
CG15765	CG15765 gene product from transcript CG15765-RA	0.015
CDase	Ceramidase	0.015
gig	gigas	0.015
Alk	CG8250 gene product from transcript CG8250-RA	0.015
mnb	minibrain	0.015
Cdc42	CG12530 gene product from transcript CG12530-RA	0.015
lap	like-AP180	0.015
Vha100-1	CG1709 gene product from transcript CG1709-RF	0.014
dpr10	CG32057 gene product from transcript CG32057-RB	0.014
CG17922	CG17922 gene product from transcript CG17922-RA	0.014
oa2	octopamine receptor 2	0.014	Rat
sif	still life	0.014
Calx	Na/Ca-exchange protein	0.014
SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	0.014
ple	pale	0.014
Act57B	Actin 57B	0.014
shep	alan shepard	0.013
Oli	Olig family	0.013
Trim9	CG31721 gene product from transcript CG31721-RB	0.013
Nmdar2	NMDA receptor 2	0.012
Vrp1	Verprolin 1	0.012
rdgC	retinal degeneration C	0.012
Yp2	Yolk protein 2	0.012
CG4660	CG4660 gene product from transcript CG4660-RA	0.012
CrebB-17A	Cyclic-AMP response element binding protein B at 17A	0.012
dnr1	defense repressor 1	0.011
trio	CG18214 gene product from transcript CG18214-RA	0.011
Ca-alpha1D	Ca[2+]-channel protein alpha[[1]] subunit D	0.011
slo	slowpoke	0.011
spas	spastin	0.011
spi	spitz	0.011
Ras85D	Ras oncogene at 85D	0.011
Pgk	Phosphoglycerate kinase	0.011
cv-c	crossveinless c	0.011
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.011
laza	lazaro	0.011
kay	kayak	0.011
t	tan	0.011
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.011
gogo	golden goal	0.011
rost	rolling stone	0.011
nompC	no mechanoreceptor potential C	0.011
CG13108	CG13108 gene product from transcript CG13108-RA	0.011
CG14234	CG14234 gene product from transcript CG14234-RA	0.011
CanA-14F	Calcineurin A at 14F	0.010
DmsR-2	Dromyosuppressin receptor 2	0.010
Sox100B	CG15552 gene product from transcript CG15552-RA	0.010
Task6	CG9637 gene product from transcript CG9637-RC	0.010
trpml	transient receptor potential mucolipin	0.010
hig	hikaru genki	0.010
Dh31-R1	Diuretic hormone 31 receptor 1	0.010
synj	synaptojanin	0.010	Worm
Eaat1	Excitatory amino acid transporter 1	0.010