IMP

Process View

Homo sapiens

22 genes annotated in human

Multi-species View

positive regulation of cell cell adhesion

GO:0022409

Any process that activates or increases the rate or extent of cell adhesion to another cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of cell cell adhesion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of cell cell adhesion" (in gray)

Name	Description	Probability	Func Analog Organism
TEK	TEK tyrosine kinase, endothelial	0.945
SMAD3	SMAD family member 3	0.923	Human
SMAD2	SMAD family member 2	0.908	Human
CCR5	chemokine (C-C motif) receptor 5	0.746
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.723
FGA	fibrinogen alpha chain	0.643
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.620
FGB	fibrinogen beta chain	0.582
IL8	interleukin 8	0.548
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.497
IL1R1	interleukin 1 receptor, type I	0.491
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.455
CCL2	chemokine (C-C motif) ligand 2	0.452	Human
SMAD1	SMAD family member 1	0.292	Human
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.263
SMAD7	SMAD family member 7	0.245
ICAM1	intercellular adhesion molecule 1	0.221
CCL4	chemokine (C-C motif) ligand 4	0.208	Human
ITGB5	integrin, beta 5	0.171
PTPRC	protein tyrosine phosphatase, receptor type, C	0.169
IL6	interleukin 6 (interferon, beta 2)	0.151
CXCL2	chemokine (C-X-C motif) ligand 2	0.141
CCL8	chemokine (C-C motif) ligand 8	0.141	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.135
INHBA	inhibin, beta A	0.129
SMAD5	SMAD family member 5	0.122	Human
VCAM1	vascular cell adhesion molecule 1	0.116
FGG	fibrinogen gamma chain	0.114
CXCL3	chemokine (C-X-C motif) ligand 3	0.109
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.106
BMP2	bone morphogenetic protein 2	0.105
PDIA3	protein disulfide isomerase family A, member 3	0.101
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.099
IL1B	interleukin 1, beta	0.093
CCL20	chemokine (C-C motif) ligand 20	0.092	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.091
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.090	Human
IDE	insulin-degrading enzyme	0.083
RNF11	ring finger protein 11	0.077
SMAD6	SMAD family member 6	0.070	Human
MSN	moesin	0.069
IFNG	interferon, gamma	0.065
FAS	Fas (TNF receptor superfamily, member 6)	0.063
PLAUR	plasminogen activator, urokinase receptor	0.063
BBS10	Bardet-Biedl syndrome 10	0.062
FN1	fibronectin 1	0.060
BMPR1B	bone morphogenetic protein receptor, type IB	0.057
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.055
TCF4	transcription factor 4	0.053
CFLAR	CASP8 and FADD-like apoptosis regulator	0.051
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.051
TGFB1	transforming growth factor, beta 1	0.049
IL1R2	interleukin 1 receptor, type II	0.048
CCL13	chemokine (C-C motif) ligand 13	0.045	Human
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.041
CRP	C-reactive protein, pentraxin-related	0.041
FBN1	fibrillin 1	0.040
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.039
CXCL10	chemokine (C-X-C motif) ligand 10	0.038
FBLN1	fibulin 1	0.033
CCR7	chemokine (C-C motif) receptor 7	0.032
SMAD4	SMAD family member 4	0.032	Human
BMPR1A	bone morphogenetic protein receptor, type IA	0.032
CCR1	chemokine (C-C motif) receptor 1	0.032
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.031	Human
TGFBR1	transforming growth factor, beta receptor 1	0.031
PLEK	pleckstrin	0.030
NIPSNAP3A	nipsnap homolog 3A (C. elegans)	0.030
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.029
BMP4	bone morphogenetic protein 4	0.029
LAPTM5	lysosomal protein transmembrane 5	0.028
SOD2	superoxide dismutase 2, mitochondrial	0.028
DARC	Duffy blood group, chemokine receptor	0.027
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.027
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.027
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.027
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.027
CXCL5	chemokine (C-X-C motif) ligand 5	0.027
ANGPT2	angiopoietin 2	0.026	Human
CXCL11	chemokine (C-X-C motif) ligand 11	0.026
HIC1	hypermethylated in cancer 1	0.025
CD14	CD14 molecule	0.025
FHL2	four and a half LIM domains 2	0.023
SELE	selectin E	0.023
BCL2A1	BCL2-related protein A1	0.023
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.023
CPE	carboxypeptidase E	0.023
CH25H	cholesterol 25-hydroxylase	0.022
CCL19	chemokine (C-C motif) ligand 19	0.022	Human
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.022
CCL3	chemokine (C-C motif) ligand 3	0.022	Human
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.022
ENG	endoglin	0.021
TFPI2	tissue factor pathway inhibitor 2	0.021
IL18RAP	interleukin 18 receptor accessory protein	0.020
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.020
PI3	peptidase inhibitor 3, skin-derived	0.020
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.020
FZD1	frizzled homolog 1 (Drosophila)	0.020
UBD	ubiquitin D	0.020
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.019
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.019
NOG	noggin	0.018
IL7R	interleukin 7 receptor	0.018
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.018
CD83	CD83 molecule	0.018
EZR	ezrin	0.017
DPP4	dipeptidyl-peptidase 4	0.017
CALML3	calmodulin-like 3	0.016
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.016
CCL22	chemokine (C-C motif) ligand 22	0.016
GLIS2	GLIS family zinc finger 2	0.016
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.016
OSMR	oncostatin M receptor	0.016
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.016
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.016
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.015
DPT	dermatopontin	0.015
CCR3	chemokine (C-C motif) receptor 3	0.015
IL10	interleukin 10	0.015
FNBP1	formin binding protein 1	0.015
CSF3	colony stimulating factor 3 (granulocyte)	0.014
MKL2	MKL/myocardin-like 2	0.014
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	0.014
IQGAP1	IQ motif containing GTPase activating protein 1	0.014
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.014
CCL7	chemokine (C-C motif) ligand 7	0.014	Human
CCL21	chemokine (C-C motif) ligand 21	0.014
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.014
LRP6	low density lipoprotein receptor-related protein 6	0.014
JUP	junction plakoglobin	0.014
TGFB3	transforming growth factor, beta 3	0.013
ALB	albumin	0.013
STC1	stanniocalcin 1	0.013
CXXC5	CXXC finger protein 5	0.013
NLK	nemo-like kinase	0.013
GPR109B	G protein-coupled receptor 109B	0.013
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.013
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.013
TREM1	triggering receptor expressed on myeloid cells 1	0.013
SOX7	SRY (sex determining region Y)-box 7	0.013
C1orf93	chromosome 1 open reading frame 93	0.013
KIF3A	kinesin family member 3A	0.012
TNC	tenascin C	0.012
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.012
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.012
NOV	nephroblastoma overexpressed gene	0.012
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.012
ACBD3	acyl-CoA binding domain containing 3	0.012
ARHGAP5	Rho GTPase activating protein 5	0.012
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.012
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.012
TRAF4	TNF receptor-associated factor 4	0.012
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.012
HBEGF	heparin-binding EGF-like growth factor	0.012
CCL11	chemokine (C-C motif) ligand 11	0.012	Human
ANGPT1	angiopoietin 1	0.011	Human
FRZB	frizzled-related protein	0.011
IL1A	interleukin 1, alpha	0.011	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.011	Mouse
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.011
COL13A1	collagen, type XIII, alpha 1	0.011
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.011
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.011
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.011	Human
RUNX3	runt-related transcription factor 3	0.011
NLRP3	NLR family, pyrin domain containing 3	0.011
SMN1	survival of motor neuron 1, telomeric	0.011
ZC3H12A	zinc finger CCCH-type containing 12A	0.011
FPR3	formyl peptide receptor 3	0.011
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.011
APC	adenomatous polyposis coli	0.011
ELN	elastin	0.011
ZEB2	zinc finger E-box binding homeobox 2	0.010
GPC1	glypican 1	0.010
YY1	YY1 transcription factor	0.010
F2	coagulation factor II (thrombin)	0.010
NRP1	neuropilin 1	0.010
CCL1	chemokine (C-C motif) ligand 1	0.010
LRRC32	leucine rich repeat containing 32	0.010
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.010
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.010
PRRX1	paired related homeobox 1	0.010
RNF111	ring finger protein 111	0.010
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.010
EP300	E1A binding protein p300	0.010
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.010