IMP

Process View

Homo sapiens

18 genes annotated in human

regulation of myotube differentiation

Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.

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Known genes in the process in human Include functional analogs

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Gene Predictions

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Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of myotube differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	0.996	Human
NOTCH1	notch 1	0.982
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.974	Human
HDAC4	histone deacetylase 4	0.957
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.951
JAG1	jagged 1	0.942
TTN	titin	0.896
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.780
CEACAM5	carcinoembryonic antigen-related cell adhesion molecule 5	0.759
PSG9	pregnancy specific beta-1-glycoprotein 9	0.695	Human
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.511
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.504
TBX5	T-box 5	0.447	Human
PSG6	pregnancy specific beta-1-glycoprotein 6	0.296	Human
IL4R	interleukin 4 receptor	0.286	Mouse
MYH7B	myosin, heavy chain 7B, cardiac muscle, beta	0.270
ATF3	activating transcription factor 3	0.256
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.253
FSTL1	follistatin-like 1	0.240
NOTCH3	notch 3	0.222	Human
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.183
PARVA	parvin, alpha	0.175
BMPR1A	bone morphogenetic protein receptor, type IA	0.175
NCOR2	nuclear receptor corepressor 2	0.161
MEF2C	myocyte enhancer factor 2C	0.160
ENG	endoglin	0.157
BCL2L1	BCL2-like 1	0.154
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.152
BCL6	B-cell CLL/lymphoma 6	0.150
CEACAM7	carcinoembryonic antigen-related cell adhesion molecule 7	0.138	Human
DPP4	dipeptidyl-peptidase 4	0.132
MEF2A	myocyte enhancer factor 2A	0.118	Human
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.116
PSG4	pregnancy specific beta-1-glycoprotein 4	0.112
PTK2	PTK2 protein tyrosine kinase 2	0.107
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.089
ATXN1	ataxin 1	0.084
PTRF	polymerase I and transcript release factor	0.077
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.074
CNOT8	CCR4-NOT transcription complex, subunit 8	0.074
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.065
LIMS1	LIM and senescent cell antigen-like domains 1	0.064
TP53	tumor protein p53	0.060
FBLN1	fibulin 1	0.055
FN1	fibronectin 1	0.055
PRKD2	protein kinase D2	0.054
PSG5	pregnancy specific beta-1-glycoprotein 5	0.051	Human
IL2RG	interleukin 2 receptor, gamma	0.050
CXCL11	chemokine (C-X-C motif) ligand 11	0.049
NCOR1	nuclear receptor corepressor 1	0.049
COL1A2	collagen, type I, alpha 2	0.048
DLL1	delta-like 1 (Drosophila)	0.047
MAP2K3	mitogen-activated protein kinase kinase 3	0.046
IL4	interleukin 4	0.045	Mouse
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.043
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.040
PAX8	paired box 8	0.039
RARA	retinoic acid receptor, alpha	0.036
NOTCH2NL	notch 2 N-terminal like	0.034
PXN	paxillin	0.034	Fly
PSG3	pregnancy specific beta-1-glycoprotein 3	0.033
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.032	Human
IRS1	insulin receptor substrate 1	0.031
JUN	jun proto-oncogene	0.031
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.031
INO80B	INO80 complex subunit B	0.030
PLCG1	phospholipase C, gamma 1	0.030
PSG1	pregnancy specific beta-1-glycoprotein 1	0.030
PNRC1	proline-rich nuclear receptor coactivator 1	0.028
IGF2	insulin-like growth factor 2 (somatomedin A)	0.026
PML	promyelocytic leukemia	0.026
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.026
GATA4	GATA binding protein 4	0.026
DBP	D site of albumin promoter (albumin D-box) binding protein	0.026
VIM	vimentin	0.024
JAG2	jagged 2	0.024
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.024
H3F3C	H3 histone, family 3C	0.024
MAML1	mastermind-like 1 (Drosophila)	0.024
AR	androgen receptor	0.024
TGFB3	transforming growth factor, beta 3	0.023
ANKFY1	ankyrin repeat and FYVE domain containing 1	0.023
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.023
HSPG2	heparan sulfate proteoglycan 2	0.022
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.022
EP300	E1A binding protein p300	0.022
IQGAP1	IQ motif containing GTPase activating protein 1	0.021
MYL9	myosin, light chain 9, regulatory	0.021
BCAR1	breast cancer anti-estrogen resistance 1	0.021
HDAC9	histone deacetylase 9	0.020	Human Mouse
IGFBP4	insulin-like growth factor binding protein 4	0.020	Human
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.019
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.019
ADAM12	ADAM metallopeptidase domain 12	0.019
PSG7	pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)	0.018
TRIM43	tripartite motif containing 43	0.018
COL1A1	collagen, type I, alpha 1	0.018
EPAS1	endothelial PAS domain protein 1	0.017
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.017
TNS1	tensin 1	0.016
RPTOR	regulatory associated protein of MTOR, complex 1	0.016
UBD	ubiquitin D	0.016
BTG1	B-cell translocation gene 1, anti-proliferative	0.016
COL6A2	collagen, type VI, alpha 2	0.016
INVS	inversin	0.015
MKL1	megakaryoblastic leukemia (translocation) 1	0.015
ELSPBP1	epididymal sperm binding protein 1	0.015
NRP1	neuropilin 1	0.015
NCOA6	nuclear receptor coactivator 6	0.015
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.014
PSG2	pregnancy specific beta-1-glycoprotein 2	0.014
BTG2	BTG family, member 2	0.014	Human
FUNDC2	FUN14 domain containing 2	0.014
RB1	retinoblastoma 1	0.014
RHEB	Ras homolog enriched in brain	0.014
THBS1	thrombospondin 1	0.014
FST	follistatin	0.013
IGFBP5	insulin-like growth factor binding protein 5	0.013	Human
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.013
FOXP3	forkhead box P3	0.013
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.013
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.013
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.013
PHF21A	PHD finger protein 21A	0.013
MYOD1	myogenic differentiation 1	0.013
HES1	hairy and enhancer of split 1, (Drosophila)	0.012
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.012
TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.012
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.012
MYOG	myogenin (myogenic factor 4)	0.012	Human Mouse
BMP2	bone morphogenetic protein 2	0.012	Human
NBL1	neuroblastoma, suppression of tumorigenicity 1	0.011
SFN	stratifin	0.011
IGFBP6	insulin-like growth factor binding protein 6	0.011	Human
DUSP1	dual specificity phosphatase 1	0.011
RICTOR	RPTOR independent companion of MTOR, complex 2	0.011
CNOT6L	CCR4-NOT transcription complex, subunit 6-like	0.011
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.011
ZFYVE9	zinc finger, FYVE domain containing 9	0.010
BTF3	basic transcription factor 3	0.010
IGF1R	insulin-like growth factor 1 receptor	0.010
NCK2	NCK adaptor protein 2	0.010
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.010
GABPB2	GA binding protein transcription factor, beta subunit 2	0.010