IMP

Process View

Homo sapiens

11 genes annotated in human

positive regulation of tyrosine phosphorylation of stat5 protein

Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat5 protein.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of tyrosine phosphorylation of stat5 protein"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of tyrosine phosphorylation of stat5 protein" (in gray)

Name	Description	Probability	Func Analog Organism
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	1.000	Human
EGFR	epidermal growth factor receptor	1.000	Human
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.997
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.987
GRB2	growth factor receptor-bound protein 2	0.985
LAT	linker for activation of T cells	0.973
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.961	Human
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.952	Human
GH1	growth hormone 1	0.946
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.819
ITGB1BP3	integrin beta 1 binding protein 3	0.779
SOS1	son of sevenless homolog 1 (Drosophila)	0.769
IGF1R	insulin-like growth factor 1 receptor	0.764
CSH1	chorionic somatomammotropin hormone 1 (placental lactogen)	0.762	Human
IL23A	interleukin 23, alpha subunit p19	0.758
INSR	insulin receptor	0.754
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.677
SYK	spleen tyrosine kinase	0.673
VEGFA	vascular endothelial growth factor A	0.669
GAB1	GRB2-associated binding protein 1	0.653
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.634	Human
CSHL1	chorionic somatomammotropin hormone-like 1	0.472	Human
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.436	Human
IL4R	interleukin 4 receptor	0.415
PLCG1	phospholipase C, gamma 1	0.398
CSH2	chorionic somatomammotropin hormone 2	0.352	Human
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.336
JAK2	Janus kinase 2	0.328	Mouse
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.324	Human
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.321
GHR	growth hormone receptor	0.286
GAB2	GRB2-associated binding protein 2	0.283
PTPRB	protein tyrosine phosphatase, receptor type, B	0.233
SOCS3	suppressor of cytokine signaling 3	0.230
FYN	FYN oncogene related to SRC, FGR, YES	0.216
CDH5	cadherin 5, type 2 (vascular endothelium)	0.208
IRS1	insulin receptor substrate 1	0.192
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.183
NRP1	neuropilin 1	0.137
GH2	growth hormone 2	0.136	Human
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.136
FGFR1	fibroblast growth factor receptor 1	0.134
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.133
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.132
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.129
EPOR	erythropoietin receptor	0.119
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.114
CMIP	c-Maf-inducing protein	0.106
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.100
PGF	placental growth factor	0.093
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.081
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.077
JAK1	Janus kinase 1	0.077
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.074	Human
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.071
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.067
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.065
VAV1	vav 1 guanine nucleotide exchange factor	0.054
SOCS1	suppressor of cytokine signaling 1	0.049
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.048
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.043
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.043
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.041
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.038
SH3BP2	SH3-domain binding protein 2	0.038
IGF2R	insulin-like growth factor 2 receptor	0.036
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.035
SLA	Src-like-adaptor	0.032
CNTF	ciliary neurotrophic factor	0.032
PDGFA	platelet-derived growth factor alpha polypeptide	0.031
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.029
KITLG	KIT ligand	0.028
SH3KBP1	SH3-domain kinase binding protein 1	0.026
FAF1	Fas (TNFRSF6) associated factor 1	0.026
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.025
UBASH3B	ubiquitin associated and SH3 domain containing B	0.025
PECAM1	platelet/endothelial cell adhesion molecule	0.024
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.023
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.021
CD28	CD28 molecule	0.020
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.020
STAT5A	signal transducer and activator of transcription 5A	0.020
DDR2	discoidin domain receptor tyrosine kinase 2	0.019
BCAR1	breast cancer anti-estrogen resistance 1	0.017
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.016
LDLR	low density lipoprotein receptor	0.016
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.016
CD247	CD247 molecule	0.015
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.014
PDGFC	platelet derived growth factor C	0.014
ITGB1BP1	integrin beta 1 binding protein 1	0.013
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.013
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.012
IL6R	interleukin 6 receptor	0.012
IL2RG	interleukin 2 receptor, gamma	0.012
JAK3	Janus kinase 3	0.012
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.011
HCK	hemopoietic cell kinase	0.011
TEK	TEK tyrosine kinase, endothelial	0.011
SOS2	son of sevenless homolog 2 (Drosophila)	0.011
IL13	interleukin 13	0.011
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.010
PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	0.010
RET	ret proto-oncogene	0.010
TLR3	toll-like receptor 3	0.010
CAV1	caveolin 1, caveolae protein, 22kDa	0.010
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.010
OSM	oncostatin M	0.010
STAT1	signal transducer and activator of transcription 1, 91kDa	0.010