IMP

Process View

Homo sapiens

1 genes annotated in human

b cell homeostasis

The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "b cell homeostasis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "b cell homeostasis" (in gray)

Name	Description	Probability	Func Analog Organism
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.968	Mouse
BCL2L1	BCL2-like 1	0.919
APAF1	apoptotic peptidase activating factor 1	0.854
BCL2	B-cell CLL/lymphoma 2	0.656	Mouse
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.625
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.564
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.405
CXCR4	chemokine (C-X-C motif) receptor 4	0.366
HDAC9	histone deacetylase 9	0.343
RIPK2	receptor-interacting serine-threonine kinase 2	0.279
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.264
MSN	moesin	0.243
HLA-DMA	major histocompatibility complex, class II, DM alpha	0.237
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.218
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.210
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.209
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.192
BAX	BCL2-associated X protein	0.179	Mouse
CARD11	caspase recruitment domain family, member 11	0.178
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.139
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.133
BAK1	BCL2-antagonist/killer 1	0.113
HLA-DMB	major histocompatibility complex, class II, DM beta	0.109
XIAP	X-linked inhibitor of apoptosis	0.104
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.101
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.100
ARNT	aryl hydrocarbon receptor nuclear translocator	0.098
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.092
BID	BH3 interacting domain death agonist	0.091
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.076	Mouse
BAD	BCL2-associated agonist of cell death	0.067
C9orf89	chromosome 9 open reading frame 89	0.064
EP300	E1A binding protein p300	0.062
NCOA6	nuclear receptor coactivator 6	0.057
LAT	linker for activation of T cells	0.056
TRAF6	TNF receptor-associated factor 6	0.055
HIPK2	homeodomain interacting protein kinase 2	0.053
RNF144B	ring finger protein 144B	0.053
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.050
PLCG1	phospholipase C, gamma 1	0.048
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.047
TNIP2	TNFAIP3 interacting protein 2	0.044
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.040
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.039
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.037	Mouse
MAPK12	mitogen-activated protein kinase 12	0.036
TNIP1	TNFAIP3 interacting protein 1	0.036
FGFR1	fibroblast growth factor receptor 1	0.035
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.035
MAPK14	mitogen-activated protein kinase 14	0.034
ZNF282	zinc finger protein 282	0.032
WASL	Wiskott-Aldrich syndrome-like	0.032
LAPTM5	lysosomal protein transmembrane 5	0.032
BCL10	B-cell CLL/lymphoma 10	0.030
NCOA2	nuclear receptor coactivator 2	0.030
NCOA3	nuclear receptor coactivator 3	0.025
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.025
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.025
TNF	tumor necrosis factor	0.025
RNR2	l-rRNA	0.024
GAB1	GRB2-associated binding protein 1	0.024
BCL2L2	BCL2-like 2	0.023
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.023	Mouse
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.023
BIRC3	baculoviral IAP repeat containing 3	0.023
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.022
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.022
EZR	ezrin	0.022
BIK	BCL2-interacting killer (apoptosis-inducing)	0.021
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.021
CASP6	caspase 6, apoptosis-related cysteine peptidase	0.021
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.021
DUSP6	dual specificity phosphatase 6	0.021
SPRR2D	small proline-rich protein 2D	0.020
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.019
KRT17	keratin 17	0.019
MAPK8	mitogen-activated protein kinase 8	0.019
FLNA	filamin A, alpha	0.019
BRAP	BRCA1 associated protein	0.018
KAT2B	K(lysine) acetyltransferase 2B	0.018
AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	0.018
EGLN1	egl nine homolog 1 (C. elegans)	0.018
GAB2	GRB2-associated binding protein 2	0.017
SQSTM1	sequestosome 1	0.016
MEF2A	myocyte enhancer factor 2A	0.016
CCDC85B	coiled-coil domain containing 85B	0.016
TCF4	transcription factor 4	0.016
VHL	von Hippel-Lindau tumor suppressor	0.016
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.016
AMBRA1	autophagy/beclin-1 regulator 1	0.016
INSR	insulin receptor	0.015
PURA	purine-rich element binding protein A	0.015
CUX1	cut-like homeobox 1	0.015
PYCARD	PYD and CARD domain containing	0.015
STK17B	serine/threonine kinase 17b	0.015
SLC7A11	solute carrier family 7, (cationic amino acid transporter, y+ system) member 11	0.014
CD83	CD83 molecule	0.014
AHR	aryl hydrocarbon receptor	0.014	Mouse
ADAM15	ADAM metallopeptidase domain 15	0.013
FKBP8	FK506 binding protein 8, 38kDa	0.013
BCL2A1	BCL2-related protein A1	0.013	Mouse
BIRC2	baculoviral IAP repeat containing 2	0.013
ATF2	activating transcription factor 2	0.012
IQGAP1	IQ motif containing GTPase activating protein 1	0.012
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.012
EPAS1	endothelial PAS domain protein 1	0.012
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.012
STK10	serine/threonine kinase 10	0.012
TRAF1	TNF receptor-associated factor 1	0.012
C19orf25	chromosome 19 open reading frame 25	0.012
DIABLO	diablo, IAP-binding mitochondrial protein	0.012
NEB	nebulin	0.012
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.012	Mouse
REPS2	RALBP1 associated Eps domain containing 2	0.012
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.012
VEGFB	vascular endothelial growth factor B	0.012
AXL	AXL receptor tyrosine kinase	0.011
IRF3	interferon regulatory factor 3	0.011
SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.011
CREB1	cAMP responsive element binding protein 1	0.011
ITSN2	intersectin 2	0.011
AIP	aryl hydrocarbon receptor interacting protein	0.011
RB1	retinoblastoma 1	0.011
EGLN3	egl nine homolog 3 (C. elegans)	0.011
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.011
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.010
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.010
MAVS	mitochondrial antiviral signaling protein	0.010
BBC3	BCL2 binding component 3	0.010
CCDC67	coiled-coil domain containing 67	0.010
TRAF2	TNF receptor-associated factor 2	0.010
ATM	ataxia telangiectasia mutated	0.010
TICAM1	toll-like receptor adaptor molecule 1	0.010
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.010
SPTBN1	spectrin, beta, non-erythrocytic 1	0.010