IMP

Process View

Homo sapiens

13 genes annotated in human

positive regulation of nf kappab import into nucleus

Any process that activates or increases the frequency, rate or extent of transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of nf kappab import into nucleus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of nf kappab import into nucleus" (in gray)

Name	Description	Probability	Func Analog Organism
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.995
MYD88	myeloid differentiation primary response gene (88)	0.943
IL1R1	interleukin 1 receptor, type I	0.908
IL8	interleukin 8	0.873
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.832
CCL4	chemokine (C-C motif) ligand 4	0.827	Human
FAS	Fas (TNF receptor superfamily, member 6)	0.819
CFLAR	CASP8 and FADD-like apoptosis regulator	0.799
IL1B	interleukin 1, beta	0.750
FADD	Fas (TNFRSF6)-associated via death domain	0.740
CCR5	chemokine (C-C motif) receptor 5	0.726
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.672
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.649
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.607
TRAF1	TNF receptor-associated factor 1	0.489
CXCL2	chemokine (C-X-C motif) ligand 2	0.489
CXCL3	chemokine (C-X-C motif) ligand 3	0.478
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.458
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.440
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.317
TNF	tumor necrosis factor	0.307
CCL8	chemokine (C-C motif) ligand 8	0.288	Human
IL1R2	interleukin 1 receptor, type II	0.283
BTRC	beta-transducin repeat containing	0.264	Fly
HIPK3	homeodomain interacting protein kinase 3	0.244
CCL20	chemokine (C-C motif) ligand 20	0.219	Human
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.208
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.191
CXCL9	chemokine (C-X-C motif) ligand 9	0.190
RNF31	ring finger protein 31	0.186
BIRC3	baculoviral IAP repeat containing 3	0.175
CCR1	chemokine (C-C motif) receptor 1	0.170
CCL2	chemokine (C-C motif) ligand 2	0.155	Human
FBXW2	F-box and WD repeat domain containing 2	0.150
TLR2	toll-like receptor 2	0.122
CXCL10	chemokine (C-X-C motif) ligand 10	0.115
FBXW11	F-box and WD repeat domain containing 11	0.113	Fly
IL6	interleukin 6 (interferon, beta 2)	0.104
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.092
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.088
ZNF529	zinc finger protein 529	0.081
SNAI1	snail homolog 1 (Drosophila)	0.079
RIPK2	receptor-interacting serine-threonine kinase 2	0.077
ZNF84	zinc finger protein 84	0.069
CCR7	chemokine (C-C motif) receptor 7	0.068
IRAK2	interleukin-1 receptor-associated kinase 2	0.067
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.066	Human
SKP1	S-phase kinase-associated protein 1	0.062
ZNF571	zinc finger protein 571	0.062
CCL13	chemokine (C-C motif) ligand 13	0.060	Human
IFNG	interferon, gamma	0.056
CCL22	chemokine (C-C motif) ligand 22	0.055	Human
CXCL5	chemokine (C-X-C motif) ligand 5	0.054
CXCL11	chemokine (C-X-C motif) ligand 11	0.054
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.049
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.044
CUL1	cullin 1	0.043
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.042
ITK	IL2-inducible T-cell kinase	0.041
CCR4	chemokine (C-C motif) receptor 4	0.038
IL10	interleukin 10	0.037
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.037
CCL3	chemokine (C-C motif) ligand 3	0.035	Human
CD83	CD83 molecule	0.033
DPP4	dipeptidyl-peptidase 4	0.032
ZNF260	zinc finger protein 260	0.032
CXCL13	chemokine (C-X-C motif) ligand 13	0.032
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.029
IL7R	interleukin 7 receptor	0.029
FYN	FYN oncogene related to SRC, FGR, YES	0.029
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.029
CCL5	chemokine (C-C motif) ligand 5	0.028	Human
CCL7	chemokine (C-C motif) ligand 7	0.027	Human
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.025
ZNF420	zinc finger protein 420	0.025
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.025
ZNF83	zinc finger protein 83	0.025
BCL2A1	BCL2-related protein A1	0.024
FPR3	formyl peptide receptor 3	0.024
CD2	CD2 molecule	0.024
TRIM21	tripartite motif containing 21	0.023
ZNF432	zinc finger protein 432	0.023
ACTN1	actinin, alpha 1	0.021
PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	0.021
FASLG	Fas ligand (TNF superfamily, member 6)	0.021	Human
HOXA9	homeobox A9	0.021
TREM1	triggering receptor expressed on myeloid cells 1	0.021
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.021
NLRC4	NLR family, CARD domain containing 4	0.020
FLNA	filamin A, alpha	0.020
TICAM2	toll-like receptor adaptor molecule 2	0.020
TRADD	TNFRSF1A-associated via death domain	0.019
YAP1	Yes-associated protein 1	0.018
TLR4	toll-like receptor 4	0.017
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.017
BTK	Bruton agammaglobulinemia tyrosine kinase	0.017
IL2RB	interleukin 2 receptor, beta	0.016
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.016
PLAUR	plasminogen activator, urokinase receptor	0.016
LAMP3	lysosomal-associated membrane protein 3	0.016
TRAF2	TNF receptor-associated factor 2	0.016
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.015
SELE	selectin E	0.015
ZNF585A	zinc finger protein 585A	0.015
IL1A	interleukin 1, alpha	0.015	Human
INHBA	inhibin, beta A	0.015
IL18RAP	interleukin 18 receptor accessory protein	0.014
ZNF140	zinc finger protein 140	0.014	Human
ZC3H12A	zinc finger CCCH-type containing 12A	0.013
CH25H	cholesterol 25-hydroxylase	0.013
VCAM1	vascular cell adhesion molecule 1	0.013
IDE	insulin-degrading enzyme	0.013
BCAR1	breast cancer anti-estrogen resistance 1	0.013
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.013
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.012
PI3	peptidase inhibitor 3, skin-derived	0.012
ZNF304	zinc finger protein 304	0.012
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.012
CCL11	chemokine (C-C motif) ligand 11	0.011	Human
IRF4	interferon regulatory factor 4	0.011
ADAMDEC1	ADAM-like, decysin 1	0.011
SLAMF7	SLAM family member 7	0.011
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.011	Rat
CXCR6	chemokine (C-X-C motif) receptor 6	0.011
FLNB	filamin B, beta	0.011
C1orf93	chromosome 1 open reading frame 93	0.011
TPM4	tropomyosin 4	0.011
STAT4	signal transducer and activator of transcription 4	0.011
RGS1	regulator of G-protein signaling 1	0.011
TFEC	transcription factor EC	0.010
AQP9	aquaporin 9	0.010
PYDC2	pyrin domain containing 2	0.010