IMP

Process View

Homo sapiens

15 genes annotated in human

nephron morphogenesis

GO:0072028

The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nephron morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "nephron morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	1.000
CUL3	cullin 3	0.969
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.909
FGFR1	fibroblast growth factor receptor 1	0.847
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.773
FGF10	fibroblast growth factor 10	0.764	Human
WNK4	WNK lysine deficient protein kinase 4	0.750
KLHL3	kelch-like 3 (Drosophila)	0.721
FGF1	fibroblast growth factor 1 (acidic)	0.682
FSTL1	follistatin-like 1	0.659
KLHL12	kelch-like 12 (Drosophila)	0.637	Human
BMPR1A	bone morphogenetic protein receptor, type IA	0.599
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.529
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.506
SMAD3	SMAD family member 3	0.497
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.440
MEIS1	Meis homeobox 1	0.408
MEIS2	Meis homeobox 2	0.398
NKX2-1	NK2 homeobox 1	0.340
PLCG1	phospholipase C, gamma 1	0.329
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.326
PAX8	paired box 8	0.318
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.285
NRP1	neuropilin 1	0.278
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.240
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.228
SOX2	SRY (sex determining region Y)-box 2	0.220
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.218
NOG	noggin	0.218	Mouse
DAPK1	death-associated protein kinase 1	0.214
MSN	moesin	0.211
TIMP3	TIMP metallopeptidase inhibitor 3	0.209
FGF8	fibroblast growth factor 8 (androgen-induced)	0.195
TSC22D4	TSC22 domain family, member 4	0.175
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.166
ADAM17	ADAM metallopeptidase domain 17	0.162
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.154
MEOX1	mesenchyme homeobox 1	0.152
FGF4	fibroblast growth factor 4	0.150	Human
MAGED2	melanoma antigen family D, 2	0.128
GLIS2	GLIS family zinc finger 2	0.125
KLHL2	kelch-like 2, Mayven (Drosophila)	0.119	Human
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.119
FGF18	fibroblast growth factor 18	0.114
WNT1	wingless-type MMTV integration site family, member 1	0.103	Human Mouse Fly
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.098
BCL2L1	BCL2-like 1	0.098
PAX2	paired box 2	0.080
CSNK1E	casein kinase 1, epsilon	0.074
COL2A1	collagen, type II, alpha 1	0.071
HOXB5	homeobox B5	0.068
BMP7	bone morphogenetic protein 7	0.067	Mouse
BMP2	bone morphogenetic protein 2	0.065	Human Mouse
BHLHE40	basic helix-loop-helix family, member e40	0.059
NGFR	nerve growth factor receptor	0.056
FGF3	fibroblast growth factor 3	0.055	Human
HOXA11	homeobox A11	0.052	Mouse
TGFBR1	transforming growth factor, beta receptor 1	0.051
PAX3	paired box 3	0.050
HMGA2	high mobility group AT-hook 2	0.049
HNF1A	HNF1 homeobox A	0.045
BMP4	bone morphogenetic protein 4	0.044
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.044
HOXA10	homeobox A10	0.043
ENG	endoglin	0.041
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.041
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.040
SOX1	SRY (sex determining region Y)-box 1	0.039
SNAI1	snail homolog 1 (Drosophila)	0.039
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.039
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.038
FOXA2	forkhead box A2	0.036
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.036
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.035
SIM2	single-minded homolog 2 (Drosophila)	0.034
LBX1	ladybird homeobox 1	0.033
FGF2	fibroblast growth factor 2 (basic)	0.033
PARVA	parvin, alpha	0.033
FGFR3	fibroblast growth factor receptor 3	0.031
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.031
HOXD13	homeobox D13	0.031
FGF7	fibroblast growth factor 7	0.030	Human
TAOK1	TAO kinase 1	0.030
LMO4	LIM domain only 4	0.029
TRPC1	transient receptor potential cation channel, subfamily C, member 1	0.029
CLDN4	claudin 4	0.029
INHBB	inhibin, beta B	0.028
FRS2	fibroblast growth factor receptor substrate 2	0.028
EZR	ezrin	0.028
DUSP6	dual specificity phosphatase 6	0.028
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.026
HES2	hairy and enhancer of split 2 (Drosophila)	0.026
PRMT6	protein arginine methyltransferase 6	0.026
WNT7A	wingless-type MMTV integration site family, member 7A	0.024	Human
PXN	paxillin	0.023
MED28	mediator complex subunit 28	0.023
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.023
TGFB3	transforming growth factor, beta 3	0.023
PAX7	paired box 7	0.023
TGFB2	transforming growth factor, beta 2	0.023
FOXN4	forkhead box N4	0.019
HOXD9	homeobox D9	0.019
SKIL	SKI-like oncogene	0.018
WNT10A	wingless-type MMTV integration site family, member 10A	0.018	Human
NPHP1	nephronophthisis 1 (juvenile)	0.018
MYOD1	myogenic differentiation 1	0.018
GAS1	growth arrest-specific 1	0.017
NOTCH1	notch 1	0.017
FOXD3	forkhead box D3	0.017
SFRP1	secreted frizzled-related protein 1	0.017
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	0.016
COIL	coilin	0.016
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.016
HOXB6	homeobox B6	0.016
BTRC	beta-transducin repeat containing	0.016
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.016
SOX9	SRY (sex determining region Y)-box 9	0.016	Mouse
THBS1	thrombospondin 1	0.015
DGCR14	DiGeorge syndrome critical region gene 14	0.015
GDNF	glial cell derived neurotrophic factor	0.015
HOXB9	homeobox B9	0.015
FOXL1	forkhead box L1	0.015
TAGLN2	transgelin 2	0.015
ATF7IP	activating transcription factor 7 interacting protein	0.015
IER2	immediate early response 2	0.015
OXSR1	oxidative-stress responsive 1	0.014
WT1	Wilms tumor 1	0.014
COL7A1	collagen, type VII, alpha 1	0.014
SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.013
RAX	retina and anterior neural fold homeobox	0.013
SOX11	SRY (sex determining region Y)-box 11	0.013
LAPTM5	lysosomal protein transmembrane 5	0.013
BBS1	Bardet-Biedl syndrome 1	0.013
FOXC1	forkhead box C1	0.013
PDGFA	platelet-derived growth factor alpha polypeptide	0.013
OTX2	orthodenticle homeobox 2	0.013
IHH	Indian hedgehog	0.013
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.013
HOXA5	homeobox A5	0.013
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.013
LIMS1	LIM and senescent cell antigen-like domains 1	0.012
NFE2L1	nuclear factor (erythroid-derived 2)-like 1	0.012
CALCA	calcitonin-related polypeptide alpha	0.012
PARVB	parvin, beta	0.012
OTP	orthopedia homeobox	0.012
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.012
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.012
CLDN1	claudin 1	0.011
MNX1	motor neuron and pancreas homeobox 1	0.011
NBR1	neighbor of BRCA1 gene 1	0.011
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.011
TP53	tumor protein p53	0.011
PDX1	pancreatic and duodenal homeobox 1	0.011
HOXB1	homeobox B1	0.011
ALX4	ALX homeobox 4	0.011
AMBRA1	autophagy/beclin-1 regulator 1	0.011
T	T, brachyury homolog (mouse)	0.011
VSX1	visual system homeobox 1	0.011
NEUROG2	neurogenin 2	0.011
ZNF331	zinc finger protein 331	0.011
EYA1	eyes absent homolog 1 (Drosophila)	0.011
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.011
WNT11	wingless-type MMTV integration site family, member 11	0.010
DLX4	distal-less homeobox 4	0.010
IRX5	iroquois homeobox 5	0.010
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.010
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.010
HOXC5	homeobox C5	0.010
EYA2	eyes absent homolog 2 (Drosophila)	0.010
GSK3B	glycogen synthase kinase 3 beta	0.010
CCNK	cyclin K	0.010
WNT3	wingless-type MMTV integration site family, member 3	0.010	Human