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Mus musculus

2 genes annotated in mouse

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regulation of endodermal cell fate specification

GO:0042663

Any process that mediates the specification of a cell into an endoderm cell.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of endodermal cell fate specification"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of endodermal cell fate specification" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Fgfr2	fibroblast growth factor receptor 2	1.000
Foxc1	forkhead box C1	0.999
Hand2	heart and neural crest derivatives expressed transcript 2	0.999
Gli3	GLI-Kruppel family member GLI3	0.998
Hand1	heart and neural crest derivatives expressed transcript 1	0.998
Msx1	homeobox, msh-like 1	0.998
Foxc2	forkhead box C2	0.996
Prrx1	paired related homeobox 1	0.996
Smo	smoothened homolog (Drosophila)	0.995
Sox9	SRY-box containing gene 9	0.993
Tcfap2a	transcription factor AP-2, alpha	0.993
Pax3	paired box gene 3	0.989
Otx2	orthodenticle homolog 2 (Drosophila)	0.989
Pitx2	paired-like homeodomain transcription factor 2	0.987
Tgfb2	transforming growth factor, beta 2	0.979
Bmp4	bone morphogenetic protein 4	0.977	Zebrafish
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.971
Ctnnb1	catenin (cadherin associated protein), beta 1	0.970
Tbx1	T-box 1	0.968
Msx2	homeobox, msh-like 2	0.967
Bmp7	bone morphogenetic protein 7	0.966	Zebrafish
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.965
Dlx5	distal-less homeobox 5	0.964
Fgfr1	fibroblast growth factor receptor 1	0.964	Zebrafish
Fgfr3	fibroblast growth factor receptor 3	0.956
Hes1	hairy and enhancer of split 1 (Drosophila)	0.941
Chrd	chordin	0.936
Jag1	jagged 1	0.919
Alx4	aristaless-like homeobox 4	0.915
Prrx2	paired related homeobox 2	0.910
Chd7	chromodomain helicase DNA binding protein 7	0.910
Eya1	eyes absent 1 homolog (Drosophila)	0.904
Meox2	mesenchyme homeobox 2	0.904
Fgf8	fibroblast growth factor 8	0.897	Zebrafish
Ednra	endothelin receptor type A	0.883
Gli2	GLI-Kruppel family member GLI2	0.851
Foxg1	forkhead box G1	0.845
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.840
Acvr1	activin A receptor, type 1	0.826
Rarg	retinoic acid receptor, gamma	0.819
Gata4	GATA binding protein 4	0.808
Nodal	nodal	0.792
Gbx2	gastrulation brain homeobox 2	0.787
Gsc	goosecoid homeobox	0.785
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.769
Psen1	presenilin 1	0.753
Runx2	runt related transcription factor 2	0.735
Lrp6	low density lipoprotein receptor-related protein 6	0.710
Vangl2	vang-like 2 (van gogh, Drosophila)	0.683
Wnt3a	wingless-related MMTV integration site 3A	0.650
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.614
Dll1	delta-like 1 (Drosophila)	0.545
Ptch1	patched homolog 1	0.525
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.370
Vegfa	vascular endothelial growth factor A	0.359
En1	engrailed 1	0.346
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.332
Hoxa1	homeobox A1	0.323
Isl1	ISL1 transcription factor, LIM/homeodomain	0.283
Nkx3-2	NK3 homeobox 2	0.282
Lmx1b	LIM homeobox transcription factor 1 beta	0.271
Ece1	endothelin converting enzyme 1	0.260
Alx1	ALX homeobox 1	0.214
Notch2	Notch gene homolog 2 (Drosophila)	0.213
Tgfbr2	transforming growth factor, beta receptor II	0.204
Dlx6	distal-less homeobox 6	0.199
Gata6	GATA binding protein 6	0.197
Bmp2	bone morphogenetic protein 2	0.197	Zebrafish
Pkd1	polycystic kidney disease 1 homolog	0.196
Emx2	empty spiracles homolog 2 (Drosophila)	0.174
T	brachyury	0.167
Pitx1	paired-like homeodomain transcription factor 1	0.159
Zeb1	zinc finger E-box binding homeobox 1	0.158
Efnb2	ephrin B2	0.154
Mn1	meningioma 1	0.146
Nog	noggin	0.144	Zebrafish
Alx3	aristaless-like homeobox 3	0.108
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.099	Human
Sall4	sal-like 4 (Drosophila)	0.098
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.096
Rarb	retinoic acid receptor, beta	0.094
Mesp1	mesoderm posterior 1	0.091
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.082
Fgf15	fibroblast growth factor 15	0.077
Pax2	paired box gene 2	0.076
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.074
Smad6	MAD homolog 6 (Drosophila)	0.063
Sox2	SRY-box containing gene 2	0.062
Chuk	conserved helix-loop-helix ubiquitous kinase	0.061
Fgf3	fibroblast growth factor 3	0.059
Hhex	hematopoietically expressed homeobox	0.059
Lef1	lymphoid enhancer binding factor 1	0.058
Hoxa2	homeobox A2	0.058
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.058
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.057
Rxra	retinoid X receptor alpha	0.057
Pbx1	pre B-cell leukemia transcription factor 1	0.054
Kif3a	kinesin family member 3A	0.051
Foxe3	forkhead box E3	0.051
Emx1	empty spiracles homolog 1 (Drosophila)	0.051
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.048
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.047
Tcf15	transcription factor 15	0.047
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.047
Ihh	Indian hedgehog	0.047
Fgf17	fibroblast growth factor 17	0.045	Zebrafish
Pax6	paired box gene 6	0.045
Bmper	BMP-binding endothelial regulator	0.044
Pax9	paired box gene 9	0.044
Gja1	gap junction protein, alpha 1	0.044
Foxa2	forkhead box A2	0.044
Tbx3	T-box 3	0.043
Rdh10	retinol dehydrogenase 10 (all-trans)	0.042
Tbx15	T-box 15	0.042
Fgf10	fibroblast growth factor 10	0.041
En2	engrailed 2	0.039
Wnt1	wingless-related MMTV integration site 1	0.039
Wnt6	wingless-related MMTV integration site 6	0.039
Foxh1	forkhead box H1	0.038
Lrp2	low density lipoprotein receptor-related protein 2	0.038
Cldn6	claudin 6	0.037
Pou5f1	POU domain, class 5, transcription factor 1	0.037
Tcof1	Treacher Collins Franceschetti syndrome 1, homolog	0.035
Sp6	trans-acting transcription factor 6	0.035
Hoxd11	homeobox D11	0.033
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.033
Ptk7	PTK7 protein tyrosine kinase 7	0.033
Pkd2	polycystic kidney disease 2	0.032
Rara	retinoic acid receptor, alpha	0.032
Hesx1	homeobox gene expressed in ES cells	0.032
Disp1	dispatched homolog 1 (Drosophila)	0.032
Mks1	Meckel syndrome, type 1	0.032
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.031
Hnf1a	HNF1 homeobox A	0.031	Mouse
Hmx2	H6 homeobox 2	0.031
Sox11	SRY-box containing gene 11	0.031
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.031
Nkx2-1	NK2 homeobox 1	0.030
Etv2	ets variant gene 2	0.030
Rax	retina and anterior neural fold homeobox	0.030
Tbx2	T-box 2	0.029
Odf3	outer dense fiber of sperm tails 3	0.029
Rb1	retinoblastoma 1	0.028
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.028
Tcf21	transcription factor 21	0.028
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.027
Pyy	peptide YY	0.027
Foxb1	forkhead box B1	0.026
Gata3	GATA binding protein 3	0.026
Phlda2	pleckstrin homology-like domain, family A, member 2	0.026
Fgfrl1	fibroblast growth factor receptor-like 1	0.025
Yap1	yes-associated protein 1	0.025
Ldhc	lactate dehydrogenase C	0.025
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.025
Dusp9	dual specificity phosphatase 9	0.024
Lama1	laminin, alpha 1	0.024
Edn2	endothelin 2	0.024
Hes3	hairy and enhancer of split 3 (Drosophila)	0.023
Ager	advanced glycosylation end product-specific receptor	0.023
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.023
Col4a1	collagen, type IV, alpha 1	0.023
Cdx2	caudal type homeobox 2	0.022
Foxf1a	forkhead box F1a	0.022
Rhox6	reproductive homeobox 6	0.021
Hoxb13	homeobox B13	0.021
Hoxd12	homeobox D12	0.021
Wwc2	WW, C2 and coiled-coil domain containing 2	0.021
Neurog3	neurogenin 3	0.020
Sall3	sal-like 3 (Drosophila)	0.020
Hbb-bh1	hemoglobin Z, beta-like embryonic chain	0.020
Bmp5	bone morphogenetic protein 5	0.020
Foxd2	forkhead box D2	0.020
Ret	ret proto-oncogene	0.020
Sox3	SRY-box containing gene 3	0.019
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.019
Padi3	peptidyl arginine deiminase, type III	0.019
Apc	adenomatosis polyposis coli	0.019
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.019
Ext1	exostoses (multiple) 1	0.019
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.019
Fuz	fuzzy homolog (Drosophila)	0.018
Sct	secretin	0.018
Hoxa3	homeobox A3	0.018
Pou4f3	POU domain, class 4, transcription factor 3	0.018
Ptk2	PTK2 protein tyrosine kinase 2	0.018
Cdx1	caudal type homeobox 1	0.018
Dlx2	distal-less homeobox 2	0.017
Agrp	agouti related protein	0.017
Cfc1	cripto, FRL-1, cryptic family 1	0.017
Mecom	MDS1 and EVI1 complex locus	0.017
Adra2b	adrenergic receptor, alpha 2b	0.017
Gpc3	glypican 3	0.017
Umod	uromodulin	0.017
Jag2	jagged 2	0.017
Hist1h1t	histone cluster 1, H1t	0.017
Ntf3	neurotrophin 3	0.017
Sox7	SRY-box containing gene 7	0.017
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.016
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.016
Figla	folliculogenesis specific basic helix-loop-helix	0.016
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.016
Gip	gastric inhibitory polypeptide	0.016
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.016
Pax1	paired box gene 1	0.016
Rbp2	retinol binding protein 2, cellular	0.016
Hoxd13	homeobox D13	0.015
Zic3	zinc finger protein of the cerebellum 3	0.015
Apaf1	apoptotic peptidase activating factor 1	0.015
Gja8	gap junction protein, alpha 8	0.015
Tcfap2c	transcription factor AP-2, gamma	0.015
Hoxa13	homeobox A13	0.015
Art5	ADP-ribosyltransferase 5	0.015
Pga5	pepsinogen 5, group I	0.015
Col13a1	collagen, type XIII, alpha 1	0.015
Wnt5a	wingless-related MMTV integration site 5A	0.014
Lhx3	LIM homeobox protein 3	0.014
Pcdh12	protocadherin 12	0.014
Tmprss2	transmembrane protease, serine 2	0.014
Tshz1	teashirt zinc finger family member 1	0.014
Wnt5b	wingless-related MMTV integration site 5B	0.014
Hmx3	H6 homeobox 3	0.014
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.014
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.014
1700008P20Rik	RIKEN cDNA 1700008P20 gene	0.013
Barx1	BarH-like homeobox 1	0.013
Dll3	delta-like 3 (Drosophila)	0.013
Prm1	protamine 1	0.013
Aqp8	aquaporin 8	0.013
Cdh23	cadherin 23 (otocadherin)	0.013
Ribc2	RIB43A domain with coiled-coils 2	0.013
Gjb5	gap junction protein, beta 5	0.013
Gas1	growth arrest specific 1	0.013
Tnp2	transition protein 2	0.013
Dlx3	distal-less homeobox 3	0.013
Onecut3	one cut domain, family member 3	0.013
Tcam1	testicular cell adhesion molecule 1	0.013
Pla2g10	phospholipase A2, group X	0.012
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.012
Gata5	GATA binding protein 5	0.012
Sall1	sal-like 1 (Drosophila)	0.012
Bicc1	bicaudal C homolog 1 (Drosophila)	0.012
Hnf1b	HNF1 homeobox B	0.012
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.012
Folr1	folate receptor 1 (adult)	0.012
Evx1	even skipped homeotic gene 1 homolog	0.012
Rpl38	ribosomal protein L38	0.012
Ghrl	ghrelin	0.012
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.012
Pgap1	post-GPI attachment to proteins 1	0.012
Slc26a5	solute carrier family 26, member 5	0.012
Otp	orthopedia homolog (Drosophila)	0.012
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.012
Krtap3-3	keratin associated protein 3-3	0.012
Styxl1	serine/threonine/tyrosine interacting-like 1	0.012
Tbx6	T-box 6	0.011
Tulp2	tubby-like protein 2	0.011
Pax8	paired box gene 8	0.011
Snai1	snail homolog 1 (Drosophila)	0.011
Dpep3	dipeptidase 3	0.011
Fgf4	fibroblast growth factor 4	0.011
Ptch2	patched homolog 2	0.011
Hoxd4	homeobox D4	0.011
Col2a1	collagen, type II, alpha 1	0.011
Tead4	TEA domain family member 4	0.011
Fut7	fucosyltransferase 7	0.011
Gli1	GLI-Kruppel family member GLI1	0.011
Tal2	T-cell acute lymphocytic leukemia 2	0.011
Wap	whey acidic protein	0.011
Myl7	myosin, light polypeptide 7, regulatory	0.011
Otx1	orthodenticle homolog 1 (Drosophila)	0.011
Psen2	presenilin 2	0.011
BC051019	cDNA sequence BC051019	0.011
Krt34	keratin 34	0.011
Bmp8b	bone morphogenetic protein 8b	0.011
Phox2b	paired-like homeobox 2b	0.011
Prss32	protease, serine, 32	0.011
Sox1	SRY-box containing gene 1	0.011
Theg	testicular haploid expressed gene	0.011
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.010
Hhat	hedgehog acyltransferase	0.010
Cldn9	claudin 9	0.010
Defa-rs12	defensin, alpha, related sequence 12	0.010
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.010
Smad3	MAD homolog 3 (Drosophila)	0.010
Rhox5	reproductive homeobox 5	0.010
Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.010
Ptprb	protein tyrosine phosphatase, receptor type, B	0.010
Tek	endothelial-specific receptor tyrosine kinase	0.010
Syngr4	synaptogyrin 4	0.010
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.010