IMP

Process View

Mus musculus

15 genes annotated in mouse

Multi-species View

regulation of interleukin 1 secretion

GO:0050704

Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 from a cell.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interleukin 1 secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of interleukin 1 secretion" (in gray)

Name	Description	Probability	Func Analog Organism
Ccr2	chemokine (C-C motif) receptor 2	0.964	Mouse
Ccl2	chemokine (C-C motif) ligand 2	0.954
Gbp5	guanylate binding protein 5	0.912
Lyz2	lysozyme 2	0.902
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.878
Ccr1	chemokine (C-C motif) receptor 1	0.817	Mouse
Cd44	CD44 antigen	0.787
Ccr5	chemokine (C-C motif) receptor 5	0.771	Mouse
Pycard	PYD and CARD domain containing	0.718
Ccl3	chemokine (C-C motif) ligand 3	0.638
Tlr4	toll-like receptor 4	0.603
Casp1	caspase 1	0.432
Il1b	interleukin 1 beta	0.275
Socs1	suppressor of cytokine signaling 1	0.245
Ifngr1	interferon gamma receptor 1	0.234
Il1r1	interleukin 1 receptor, type I	0.177
Selp	selectin, platelet	0.157
Mmp9	matrix metallopeptidase 9	0.147
Sh2d2a	SH2 domain protein 2A	0.112
Ccl8	chemokine (C-C motif) ligand 8	0.112
Ccl4	chemokine (C-C motif) ligand 4	0.109	Mouse
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.109
C3ar1	complement component 3a receptor 1	0.108
Xcl1	chemokine (C motif) ligand 1	0.108	Mouse
Irf1	interferon regulatory factor 1	0.094
Cd7	CD7 antigen	0.090
Il27ra	interleukin 27 receptor, alpha	0.088
Nlrp3	NLR family, pyrin domain containing 3	0.086
Il18	interleukin 18	0.074
Gzmk	granzyme K	0.072
Gzmb	granzyme B	0.064
Fas	Fas (TNF receptor superfamily member 6)	0.061
Pax2	paired box gene 2	0.061
Ifng	interferon gamma	0.061
Gzma	granzyme A	0.060
Wnt4	wingless-related MMTV integration site 4	0.059	Mouse
Ccl22	chemokine (C-C motif) ligand 22	0.058
Cxcl9	chemokine (C-X-C motif) ligand 9	0.056
Ubd	ubiquitin D	0.052
Itgax	integrin alpha X	0.051
Ctsw	cathepsin W	0.051
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.050
Gpr132	G protein-coupled receptor 132	0.049
Cd40	CD40 antigen	0.049
Muc13	mucin 13, epithelial transmembrane	0.049
Folr2	folate receptor 2 (fetal)	0.049
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.043
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.043
Cxcl13	chemokine (C-X-C motif) ligand 13	0.042
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.042
Il2rg	interleukin 2 receptor, gamma chain	0.042
Mmp12	matrix metallopeptidase 12	0.041
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.041
Fasl	Fas ligand (TNF superfamily, member 6)	0.038
Il1a	interleukin 1 alpha	0.037
Cxcl2	chemokine (C-X-C motif) ligand 2	0.036
Ptgir	prostaglandin I receptor (IP)	0.036
Ciita	class II transactivator	0.036
Il6	interleukin 6	0.035
Tnf	tumor necrosis factor	0.034
Mndal	myeloid nuclear differentiation antigen like	0.033
Ager	advanced glycosylation end product-specific receptor	0.033
Pdcd1	programmed cell death 1	0.031
Il2rb	interleukin 2 receptor, beta chain	0.031
Ccl7	chemokine (C-C motif) ligand 7	0.031	Mouse
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.031
Foxp3	forkhead box P3	0.030
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.030
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.030
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.029
Myd88	myeloid differentiation primary response gene 88	0.028
Ncr1	natural cytotoxicity triggering receptor 1	0.028
Tlr7	toll-like receptor 7	0.027
Pax1	paired box gene 1	0.026
Cd14	CD14 antigen	0.026
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.025
Cd96	CD96 antigen	0.025
Ccr3	chemokine (C-C motif) receptor 3	0.025	Mouse
Fcgr1	Fc receptor, IgG, high affinity I	0.025
Il15	interleukin 15	0.024
Cx3cr1	chemokine (C-X3-C) receptor 1	0.024	Mouse
Wnt10a	wingless related MMTV integration site 10a	0.024
AI607873	expressed sequence AI607873	0.024
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.023
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.023
Itk	IL2-inducible T-cell kinase	0.023
Mybph	myosin binding protein H	0.022
Irg1	immunoresponsive gene 1	0.022
Il12rb2	interleukin 12 receptor, beta 2	0.022
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.021
Slamf8	SLAM family member 8	0.021
Batf	basic leucine zipper transcription factor, ATF-like	0.021
Mmp3	matrix metallopeptidase 3	0.021
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.021
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.021
Wisp2	WNT1 inducible signaling pathway protein 2	0.021
Spp1	secreted phosphoprotein 1	0.021
Nobox	NOBOX oogenesis homeobox	0.021
Ccl12	chemokine (C-C motif) ligand 12	0.020	Mouse
Il10	interleukin 10	0.019
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.019
Cxcl10	chemokine (C-X-C motif) ligand 10	0.019
Pcdh12	protocadherin 12	0.018
Shh	sonic hedgehog	0.018
Fadd	Fas (TNFRSF6)-associated via death domain	0.018
Il18r1	interleukin 18 receptor 1	0.018
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.018
Fzd10	frizzled homolog 10 (Drosophila)	0.018
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.017
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.017
Prdm1	PR domain containing 1, with ZNF domain	0.017
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.017
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.016
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.016
Oc90	otoconin 90	0.016
Amhr2	anti-Mullerian hormone type 2 receptor	0.016
Tlr2	toll-like receptor 2	0.016
Il1rn	interleukin 1 receptor antagonist	0.016
Ch25h	cholesterol 25-hydroxylase	0.016
T	brachyury	0.016
Ooep	oocyte expressed protein homolog (dog)	0.016
Tpsb2	tryptase beta 2	0.015
Lhx1	LIM homeobox protein 1	0.015
Itgb2	integrin beta 2	0.015
Il17a	interleukin 17A	0.015
Il18rap	interleukin 18 receptor accessory protein	0.015
Gimap7	GTPase, IMAP family member 7	0.015
Gpr50	G-protein-coupled receptor 50	0.015
Ccl5	chemokine (C-C motif) ligand 5	0.015	Mouse
Cxcl12	chemokine (C-X-C motif) ligand 12	0.015
Xcr1	chemokine (C motif) receptor 1	0.014	Mouse
Il5	interleukin 5	0.014
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.014
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.014
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.014
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.014
Fut7	fucosyltransferase 7	0.014
Il10ra	interleukin 10 receptor, alpha	0.014
Dock1	dedicator of cytokinesis 1	0.014
Nog	noggin	0.014
Porcn	porcupine homolog (Drosophila)	0.014
Wnt3a	wingless-related MMTV integration site 3A	0.014	Mouse
Nkg7	natural killer cell group 7 sequence	0.014
Fxyd2	FXYD domain-containing ion transport regulator 2	0.014
Il1rl1	interleukin 1 receptor-like 1	0.014
Cd70	CD70 antigen	0.013
Vax1	ventral anterior homeobox containing gene 1	0.013
Cd180	CD180 antigen	0.013
Cma1	chymase 1, mast cell	0.013
Nos2	nitric oxide synthase 2, inducible	0.013
Fgf21	fibroblast growth factor 21	0.013
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.013
Lag3	lymphocyte-activation gene 3	0.013
Anxa4	annexin A4	0.013
Icam1	intercellular adhesion molecule 1	0.013
Hoxc9	homeobox C9	0.013
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.013
Srms	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites	0.013
Retnla	resistin like alpha	0.013
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.013
Il12a	interleukin 12a	0.013
Mnda	myeloid cell nuclear differentiation antigen	0.013
Tbx21	T-box 21	0.012
Aim2	absent in melanoma 2	0.012
Lgals7	lectin, galactose binding, soluble 7	0.012
Sct	secretin	0.012
Krt86	keratin 86	0.012
Bmp10	bone morphogenetic protein 10	0.012
Gzmc	granzyme C	0.012
Wnt10b	wingless related MMTV integration site 10b	0.012	Mouse
Elk4	ELK4, member of ETS oncogene family	0.012
Havcr2	hepatitis A virus cellular receptor 2	0.011
Amh	anti-Mullerian hormone	0.011
Gdnf	glial cell line derived neurotrophic factor	0.011
Cd2	CD2 antigen	0.011
Ticam1	toll-like receptor adaptor molecule 1	0.011
Chad	chondroadherin	0.011
Efna1	ephrin A1	0.011
Tbxas1	thromboxane A synthase 1, platelet	0.011
Cdx1	caudal type homeobox 1	0.011
Cd244	CD244 natural killer cell receptor 2B4	0.011
Has1	hyaluronan synthase1	0.011
Sele	selectin, endothelial cell	0.011
Muc5ac	mucin 5, subtypes A and C, tracheobronchial/gastric	0.011
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.011
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.011
Adora2a	adenosine A2a receptor	0.011
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.011
Cd160	CD160 antigen	0.011
Pou3f3	POU domain, class 3, transcription factor 3	0.011
AW112010	expressed sequence AW112010	0.011
Sit1	suppression inducing transmembrane adaptor 1	0.011
Ly6d	lymphocyte antigen 6 complex, locus D	0.011
Il10rb	interleukin 10 receptor, beta	0.010	Mouse
Cd3e	CD3 antigen, epsilon polypeptide	0.010
Il15ra	interleukin 15 receptor, alpha chain	0.010
Cd8b1	CD8 antigen, beta chain 1	0.010
Fgf15	fibroblast growth factor 15	0.010
Lta	lymphotoxin A	0.010
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.010
Irf4	interferon regulatory factor 4	0.010
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.010
Gdf15	growth differentiation factor 15	0.010