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Mus musculus

0 genes annotated in mouse

aplastic anemia

DOID:12449

An anemia that is characterized by a deficiency of red blood cells, white blood cells and platelets produced by bone marrow.

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "aplastic anemia" (in gray)

Name	Description	Probability	Func Analog Organism
Brca1	breast cancer 1	0.991
Rps10	ribosomal protein S10	0.704
Hba-a2	hemoglobin alpha, adult chain 2	0.563
Brca2	breast cancer 2	0.552	Human
Fanci	Fanconi anemia, complementation group I	0.533
BC030867	cDNA sequence BC030867	0.376
Fancd2	Fanconi anemia, complementation group D2	0.353	Human
Mcm10	minichromosome maintenance deficient 10 (S. cerevisiae)	0.301
Pms2	postmeiotic segregation increased 2 (S. cerevisiae)	0.234
Atm	ataxia telangiectasia mutated homolog (human)	0.200
LOC100502825	60S ribosomal protein L37-like	0.194
Naca	nascent polypeptide-associated complex alpha polypeptide	0.192
Rpl36a	ribosomal protein L36A	0.157
Hbb-b2	hemoglobin, beta adult minor chain	0.153
Fancg	Fanconi anemia, complementation group G	0.149
Rpl21	ribosomal protein L21	0.139
Trp53	transformation related protein 53	0.134
Mphosph9	M-phase phosphoprotein 9	0.111
Eme1	essential meiotic endonuclease 1 homolog 1 (S. pombe)	0.103
Rpl26	ribosomal protein L26	0.091
Fam54a	family with sequence similarity 54, member A	0.090
Pask	PAS domain containing serine/threonine kinase	0.089
Rps21	ribosomal protein S21	0.088
Mdm2	transformed mouse 3T3 cell double minute 2	0.084
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.082
Cenpm	centromere protein M	0.067
Nbn	nibrin	0.060	Human
Rps15a	ribosomal protein S15A	0.060
Dtl	denticleless homolog (Drosophila)	0.058
Cenpf	centromere protein F	0.057
Rps7	ribosomal protein S7	0.057
Rplp2	ribosomal protein, large P2	0.056
5730590G19Rik	RIKEN cDNA 5730590G19 gene	0.055
Rps12	ribosomal protein S12	0.051
Rpl13a	ribosomal protein L13A	0.050
Rpl27	ribosomal protein L27	0.049
Rad51	RAD51 homolog (S. cerevisiae)	0.047
Ankle1	ankyrin repeat and LEM domain containing 1	0.047
Mybl2	myeloblastosis oncogene-like 2	0.045
Rpl22	ribosomal protein L22	0.041
Pola2	polymerase (DNA directed), alpha 2	0.041
Gm10166	predicted pseudogene 10166	0.039
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.038
Apc	adenomatosis polyposis coli	0.037
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.037
Gm9846	predicted gene 9846	0.037
H2afx	H2A histone family, member X	0.035
Gins3	GINS complex subunit 3 (Psf3 homolog)	0.035
Tonsl	tonsoku-like, DNA repair protein	0.035
Rttn	rotatin	0.035
Rpl22l1	ribosomal protein L22 like 1	0.034
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.034
Palb2	partner and localizer of BRCA2	0.034
Tube1	epsilon-tubulin 1	0.034
Dclre1a	DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)	0.034
Mms22l	MMS22-like, DNA repair protein	0.033
4930427A07Rik	RIKEN cDNA 4930427A07 gene	0.033
Mis18bp1	MIS18 binding protein 1	0.031
Blm	Bloom syndrome, RecQ helicase-like	0.031
Lats1	large tumor suppressor	0.030
Exo1	exonuclease 1	0.029
Recql4	RecQ protein-like 4	0.028
Amhr2	anti-Mullerian hormone type 2 receptor	0.028
Rad54l	RAD54 like (S. cerevisiae)	0.028
Neil3	nei like 3 (E. coli)	0.028
Cwf19l1	CWF19-like 1, cell cycle control (S. pombe)	0.028
Hsf2	heat shock factor 2	0.027
Rb1	retinoblastoma 1	0.026
Lrr1	leucine rich repeat protein 1	0.026
Rpl34	ribosomal protein L34	0.026
Rpl11	ribosomal protein L11	0.025
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.025
Aspm	asp (abnormal spindle)-like, microcephaly associated (Drosophila)	0.024
Gen1	Gen homolog 1, endonuclease (Drosophila)	0.024
Mastl	microtubule associated serine/threonine kinase-like	0.024
Cntrob	centrobin, centrosomal BRCA2 interacting protein	0.023
Ahsp	alpha hemoglobin stabilizing protein	0.022
Ribc1	RIB43A domain with coiled-coils 1	0.022
2610021K21Rik	RIKEN cDNA 2610021K21 gene	0.021
Cenpn	centromere protein N	0.021
Orc1	origin recognition complex, subunit 1	0.021
E2f1	E2F transcription factor 1	0.021
Casc5	cancer susceptibility candidate 5	0.021
Kif24	kinesin family member 24	0.021
Atr	ataxia telangiectasia and Rad3 related	0.021
Beta-s	hemoglobin subunit beta-1-like	0.020
Tmem194	transmembrane protein 194	0.020
Fancm	Fanconi anemia, complementation group M	0.020	Human
Lig4	ligase IV, DNA, ATP-dependent	0.020
Ccdc77	coiled-coil domain containing 77	0.020
Mre11a	meiotic recombination 11 homolog A (S. cerevisiae)	0.019
Rad18	RAD18 homolog (S. cerevisiae)	0.019
Use1	unconventional SNARE in the ER 1 homolog (S. cerevisiae)	0.019
Rps27a	ribosomal protein S27A	0.019
C2cd3	C2 calcium-dependent domain containing 3	0.018
Ankrd52	ankyrin repeat domain 52	0.018
Mcm8	minichromosome maintenance deficient 8 (S. cerevisiae)	0.018
Ddx11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)	0.018
Dhfr	dihydrofolate reductase	0.018
Wdr67	WD repeat domain 67	0.018
Mcph1	microcephaly, primary autosomal recessive 1	0.018
Mlf1ip	myeloid leukemia factor 1 interacting protein	0.017
Lrdd	leucine-rich and death domain containing	0.017
Rps11	ribosomal protein S11	0.017
Ankrd26	ankyrin repeat domain 26	0.017
Cep135	centrosomal protein 135	0.017
Cdca7l	cell division cycle associated 7 like	0.017
Rps28	ribosomal protein S28	0.016
Rtel1	regulator of telomere elongation helicase 1	0.016
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.016
Eef1b2	eukaryotic translation elongation factor 1 beta 2	0.016
Rpl14	ribosomal protein L14	0.016
Mnd1	meiotic nuclear divisions 1 homolog (S. cerevisiae)	0.016
E2f4	E2F transcription factor 4	0.015
Cdk5rap2	CDK5 regulatory subunit associated protein 2	0.015
Chtf18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.015
C230052I12Rik	RIKEN cDNA C230052I12 gene	0.015
Wdr90	WD repeat domain 90	0.015
Chek2	CHK2 checkpoint homolog (S. pombe)	0.015
4930534B04Rik	RIKEN cDNA 4930534B04 gene	0.015
Rps15	ribosomal protein S15	0.014
Rad51l1	RAD51-like 1 (S. cerevisiae)	0.014
Gm10063	predicted gene 10063	0.014
Ska1	spindle and kinetochore associated complex subunit 1	0.014
Mns1	meiosis-specific nuclear structural protein 1	0.014
Lsm7	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.014
Tsga14	testis specific gene A14	0.014
Cep57l1	centrosomal protein 57-like 1	0.014
Recql5	RecQ protein-like 5	0.014
Cep78	centrosomal protein 78	0.014
Rad51c	RAD51 homolog c (S. cerevisiae)	0.014	Human
Helq	helicase, POLQ-like	0.013
Sgol1	shugoshin-like 1 (S. pombe)	0.013
Rpl5	ribosomal protein L5	0.013
Skiv2l2	superkiller viralicidic activity 2-like 2 (S. cerevisiae)	0.013
Ttll5	tubulin tyrosine ligase-like family, member 5	0.013
Hbb-b1	hemoglobin, beta adult major chain	0.013
Fanca	Fanconi anemia, complementation group A	0.013	Human
Cenpk	centromere protein K	0.013
Wwox	WW domain-containing oxidoreductase	0.013
Fam72a	family with sequence similarity 72, member A	0.013
Naa40	N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)	0.013
Mtbp	Mdm2, transformed 3T3 cell double minute p53 binding protein	0.013
2310079F23Rik	RIKEN cDNA 2310079F23 gene	0.013
Clspn	claspin homolog (Xenopus laevis)	0.013
2210009G21Rik	RIKEN cDNA 2210009G21 gene	0.013
Gm5805	predicted gene 5805	0.013
Mlh3	mutL homolog 3 (E coli)	0.012
Msh2	mutS homolog 2 (E. coli)	0.012
2610002D18Rik	RIKEN cDNA 2610002D18 gene	0.012
Rabggta	Rab geranylgeranyl transferase, a subunit	0.012
Trappc2l	trafficking protein particle complex 2-like	0.012
Cep152	centrosomal protein 152	0.012
Snx15	sorting nexin 15	0.012
Kif14	kinesin family member 14	0.012
Zranb3	zinc finger, RAN-binding domain containing 3	0.011
Rccd1	RCC1 domain containing 1	0.011
Tmem81	transmembrane protein 81	0.011
Tubd1	tubulin, delta 1	0.011
Rps9	ribosomal protein S9	0.011
Gtf2h3	general transcription factor IIH, polypeptide 3	0.011
Strada	STE20-related kinase adaptor alpha	0.011
Mdc1	mediator of DNA damage checkpoint 1	0.011
Zfp940	zinc finger protein 940	0.011
Nat9	N-acetyltransferase 9 (GCN5-related, putative)	0.011
Gm10294	predicted pseudogene 10294	0.011
Ercc8	excision repaiross-complementing rodent repair deficiency, complementation group 8	0.011
Foxm1	forkhead box M1	0.011
Iqcc	IQ motif containing C	0.011
Zfp169	zinc finger protein 169	0.011
Pms1	postmeiotic segregation increased 1 (S. cerevisiae)	0.011
Stil	Scl/Tal1 interrupting locus	0.011
1600002H07Rik	RIKEN cDNA 1600002H07 gene	0.011
Rps25	ribosomal protein S25	0.011
Rpl24	ribosomal protein L24	0.011
Snupn	snurportin 1	0.011
Dsn1	DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)	0.010
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.010
Psenen	presenilin enhancer 2 homolog (C. elegans)	0.010
Ccdc18	coiled-coil domain containing 18	0.010
Rad50	RAD50 homolog (S. cerevisiae)	0.010
2410089E03Rik	RIKEN cDNA 2410089E03 gene	0.010
Dync2h1	dynein cytoplasmic 2 heavy chain 1	0.010
Pmf1	polyamine-modulated factor 1	0.010
Zfp35	zinc finger protein 35	0.010
Aqr	aquarius	0.010
Ckap2l	cytoskeleton associated protein 2-like	0.010
Pot1b	protection of telomeres 1B	0.010
Kif15	kinesin family member 15	0.010
Kif18b	kinesin family member 18B	0.010
Rnf219	ring finger protein 219	0.010