IMP

Process View

Mus musculus

1 genes annotated in mouse

Multi-species View

negative regulation of interleukin 8 production

GO:0032717

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of interleukin 8 production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of interleukin 8 production" (in gray)

Name	Description	Probability	Func Analog Organism
Cyld	cylindromatosis (turban tumor syndrome)	0.290
Arrb2	arrestin, beta 2	0.285
Socs3	suppressor of cytokine signaling 3	0.232
Il6st	interleukin 6 signal transducer	0.215
Mvp	major vault protein	0.166
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.130
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.124
Lgals3	lectin, galactose binding, soluble 3	0.122
Klf3	Kruppel-like factor 3 (basic)	0.120
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.120
Dysf	dysferlin	0.106
Cd44	CD44 antigen	0.097
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.084
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.077
Sit1	suppression inducing transmembrane adaptor 1	0.071
5830411N06Rik	RIKEN cDNA 5830411N06 gene	0.069	Mouse
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.067
Dync1h1	dynein cytoplasmic 1 heavy chain 1	0.067
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.060
Anxa3	annexin A3	0.055
Klf2	Kruppel-like factor 2 (lung)	0.050
Tnf	tumor necrosis factor	0.047
S100a6	S100 calcium binding protein A6 (calcyclin)	0.046
Klf6	Kruppel-like factor 6	0.045
Zap70	zeta-chain (TCR) associated protein kinase	0.044
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.043
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.043
Anxa2	annexin A2	0.040
Cd8a	CD8 antigen, alpha chain	0.037
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.037
Fos	FBJ osteosarcoma oncogene	0.035
Cd3e	CD3 antigen, epsilon polypeptide	0.033
Cd9	CD9 antigen	0.032
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.032
Icos	inducible T-cell co-stimulator	0.032
Ms4a15	membrane-spanning 4-domains, subfamily A, member 15	0.032
Pdcd1	programmed cell death 1	0.031
S100a10	S100 calcium binding protein A10 (calpactin)	0.031
S1pr4	sphingosine-1-phosphate receptor 4	0.030
Litaf	LPS-induced TN factor	0.029
Cenpj	centromere protein J	0.029
Nupr1	nuclear protein 1	0.029
Camp	cathelicidin antimicrobial peptide	0.029
Zfp36	zinc finger protein 36	0.028
Fiz1	Flt3 interacting zinc finger protein 1	0.028
Tmem89	transmembrane protein 89	0.027
Csf1	colony stimulating factor 1 (macrophage)	0.026
Anxa5	annexin A5	0.026
Slc36a3	solute carrier family 36 (proton/amino acid symporter), member 3	0.026
Pbx2	pre B-cell leukemia transcription factor 2	0.025
Gja1	gap junction protein, alpha 1	0.025
Ngp	neutrophilic granule protein	0.023
Osmr	oncostatin M receptor	0.023
Itk	IL2-inducible T-cell kinase	0.022
Mmp8	matrix metallopeptidase 8	0.022
Mpo	myeloperoxidase	0.022
Klf1	Kruppel-like factor 1 (erythroid)	0.021
Tff1	trefoil factor 1	0.021
2310007L24Rik	RIKEN cDNA 2310007L24 gene	0.020
Atf3	activating transcription factor 3	0.019
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.019
Add1	adducin 1 (alpha)	0.019
Cxcr3	chemokine (C-X-C motif) receptor 3	0.019
Prtn3	proteinase 3	0.018
Gfi1b	growth factor independent 1B	0.018
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.018
Serpinb6a	serine (or cysteine) peptidase inhibitor, clade B, member 6a	0.018
Jak3	Janus kinase 3	0.018
Igll1	immunoglobulin lambda-like polypeptide 1	0.018
Il2rb	interleukin 2 receptor, beta chain	0.017
Fcnb	ficolin B	0.017
Cela2a	chymotrypsin-like elastase family, member 2A	0.017
Olfr90	olfactory receptor 90	0.017
Ltb4r1	leukotriene B4 receptor 1	0.017
Ltf	lactotransferrin	0.017
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.017
Siglecg	sialic acid binding Ig-like lectin G	0.017
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.017
Pglyrp2	peptidoglycan recognition protein 2	0.017
Col11a2	collagen, type XI, alpha 2	0.017
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.017
Diap1	diaphanous homolog 1 (Drosophila)	0.016
Lta	lymphotoxin A	0.016
Dusp1	dual specificity phosphatase 1	0.016
S100a11	S100 calcium binding protein A11 (calgizzarin)	0.016
Tal1	T-cell acute lymphocytic leukemia 1	0.016
Gpr114	G protein-coupled receptor 114	0.016
Sos1	son of sevenless homolog 1 (Drosophila)	0.016
Blk	B lymphoid kinase	0.016
Rltpr	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing	0.016
Iqgap1	IQ motif containing GTPase activating protein 1	0.016
Jun	Jun oncogene	0.016
Btg2	B-cell translocation gene 2, anti-proliferative	0.015
Cd19	CD19 antigen	0.015
Dnase1l1	deoxyribonuclease 1-like 1	0.015
Fcna	ficolin A	0.015
Cd163l1	CD163 molecule-like 1	0.015	Mouse
Hp	haptoglobin	0.015
Junb	Jun-B oncogene	0.015
Wdr95	WD40 repeat domain 95	0.015
Cd5	CD5 antigen	0.015
Nap1l4	nucleosome assembly protein 1-like 4	0.015
Ctnnb1	catenin (cadherin associated protein), beta 1	0.015
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.015
Socs1	suppressor of cytokine signaling 1	0.015
Pkd1	polycystic kidney disease 1 homolog	0.015
Tmc6	transmembrane channel-like gene family 6	0.015
Sgpl1	sphingosine phosphate lyase 1	0.015
Ifngr1	interferon gamma receptor 1	0.014
Rgs14	regulator of G-protein signaling 14	0.014
Hbegf	heparin-binding EGF-like growth factor	0.014
Vwf	Von Willebrand factor homolog	0.014
Lyve1	lymphatic vessel endothelial hyaluronan receptor 1	0.014
E230025N22Rik	Riken cDNA E230025N22 gene	0.014
Ccr6	chemokine (C-C motif) receptor 6	0.014
Zbtb7b	zinc finger and BTB domain containing 7B	0.014
Grlf1	glucocorticoid receptor DNA binding factor 1	0.014
Icam1	intercellular adhesion molecule 1	0.014
Rhoh	ras homolog gene family, member H	0.014
Ctnna1	catenin (cadherin associated protein), alpha 1	0.014
Prkcd	protein kinase C, delta	0.014
Gch1	GTP cyclohydrolase 1	0.014
Il13ra1	interleukin 13 receptor, alpha 1	0.013
Batf	basic leucine zipper transcription factor, ATF-like	0.013
Ski	ski sarcoma viral oncogene homolog (avian)	0.013
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.013
Slpi	secretory leukocyte peptidase inhibitor	0.013
Ahnak	AHNAK nucleoprotein (desmoyokin)	0.013
Ggn	gametogenetin	0.013
Sqstm1	sequestosome 1	0.013
Cxcl1	chemokine (C-X-C motif) ligand 1	0.013
Prss27	protease, serine, 27	0.013
Gadd45b	growth arrest and DNA-damage-inducible 45 beta	0.013
Ctsw	cathepsin W	0.013
2410004A20Rik	RIKEN cDNA 2410004A20 gene	0.013
Ppp1r13l	protein phosphatase 1, regulatory (inhibitor) subunit 13 like	0.013
Zc3h12a	zinc finger CCCH type containing 12A	0.013
S100a4	S100 calcium binding protein A4	0.013
Cd27	CD27 antigen	0.013
Cldn13	claudin 13	0.013
Acbd3	acyl-Coenzyme A binding domain containing 3	0.013
Rab20	RAB20, member RAS oncogene family	0.013
Cerk	ceramide kinase	0.012
Rnh1	ribonuclease/angiogenin inhibitor 1	0.012
Dennd5a	DENN/MADD domain containing 5A	0.012
Folr4	folate receptor 4 (delta)	0.012
Ptgs1	prostaglandin-endoperoxide synthase 1	0.012
Il1r2	interleukin 1 receptor, type II	0.012
Aqp12	aquaporin 12	0.012
Trib3	tribbles homolog 3 (Drosophila)	0.012
Hif1a	hypoxia inducible factor 1, alpha subunit	0.012
Tnip1	TNFAIP3 interacting protein 1	0.012
Ier3	immediate early response 3	0.012
Ptprcap	protein tyrosine phosphatase, receptor type, C polypeptide-associated protein	0.012
Tsc2	tuberous sclerosis 2	0.012
Ager	advanced glycosylation end product-specific receptor	0.012
Chi3l3	chitinase 3-like 3	0.012
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.012
P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide	0.012
Rinl	Ras and Rab interactor-like	0.012
F2rl3	coagulation factor II (thrombin) receptor-like 3	0.012
Galntl2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2	0.012
Epo	erythropoietin	0.012
Prg2	proteoglycan 2, bone marrow	0.012
Vav1	vav 1 oncogene	0.012
Asah1	N-acylsphingosine amidohydrolase 1	0.011
H2-Oa	histocompatibility 2, O region alpha locus	0.011
Ubash3a	ubiquitin associated and SH3 domain containing, A	0.011
Rnase4	ribonuclease, RNase A family 4	0.011
Plaur	plasminogen activator, urokinase receptor	0.011
Thbd	thrombomodulin	0.011
Hhipl1	hedgehog interacting protein-like 1	0.011
Egln1	EGL nine homolog 1 (C. elegans)	0.011
Pabpc1l	poly(A) binding protein, cytoplasmic 1-like	0.011
D630042P16Rik	RIKEN cDNA D630042P16 gene	0.011
Sri	sorcin	0.011
Spn	sialophorin	0.011
Steap4	STEAP family member 4	0.011
Anxa7	annexin A7	0.011
Emp1	epithelial membrane protein 1	0.011
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.011
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.011
Nf2	neurofibromatosis 2	0.011
Egfr	epidermal growth factor receptor	0.011
Lce3b	late cornified envelope 3B	0.011
Thbs1	thrombospondin 1	0.011
Prss54	protease, serine, 54	0.011
Fbll1	fibrillarin-like 1	0.011
Spns3	spinster homolog 3 (Drosophila)	0.011
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.011
Stk40	serine/threonine kinase 40	0.011
Ltb	lymphotoxin B	0.011
Tspan32	tetraspanin 32	0.011
Itch	itchy, E3 ubiquitin protein ligase	0.011
Spaca4	sperm acrosome associated 4	0.011
Saa3	serum amyloid A 3	0.011
Gas2l2	growth arrest-specific 2 like 2	0.011
Cxcr7	chemokine (C-X-C motif) receptor 7	0.011
Ccl6	chemokine (C-C motif) ligand 6	0.011
P2rx4	purinergic receptor P2X, ligand-gated ion channel 4	0.010
Raf1	v-raf-leukemia viral oncogene 1	0.010
Cd3d	CD3 antigen, delta polypeptide	0.010
2310021H06Rik	RIKEN cDNA 2310021H06 gene	0.010
Ets2	E26 avian leukemia oncogene 2, 3' domain	0.010
Fbxo24	F-box protein 24	0.010
Fuca1	fucosidase, alpha-L- 1, tissue	0.010
1700020L24Rik	RIKEN cDNA 1700020L24 gene	0.010
Lat	linker for activation of T cells	0.010
Cd14	CD14 antigen	0.010
Mdfic	MyoD family inhibitor domain containing	0.010
Pim1	proviral integration site 1	0.010
2310061N02Rik	RIKEN cDNA 2310061N02 gene	0.010
Stom	stomatin	0.010
Myadm	myeloid-associated differentiation marker	0.010
AI607873	expressed sequence AI607873	0.010
Nfkbid	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta	0.010
Rya3	antimicrobial peptide RYA3	0.010
Rtn3	reticulon 3	0.010
Pros1	protein S (alpha)	0.010
Extl3	exostoses (multiple)-like 3	0.010
Ccr7	chemokine (C-C motif) receptor 7	0.010
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.010
Patl2	protein associated with topoisomerase II homolog 2 (yeast)	0.010