IMP

Process View

Mus musculus

15 genes annotated in mouse

regulation of oxidoreductase activity

Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of oxidoreductase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of oxidoreductase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Lepr	leptin receptor	0.432
Pten	phosphatase and tensin homolog	0.336
Nos3	nitric oxide synthase 3, endothelial cell	0.319
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.179
Lyz2	lysozyme 2	0.138
Trp53	transformation related protein 53	0.123
Tgfbr1	transforming growth factor, beta receptor I	0.104
Tnf	tumor necrosis factor	0.102
Ctnnb1	catenin (cadherin associated protein), beta 1	0.089
Tgfbr2	transforming growth factor, beta receptor II	0.085
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.073
Fas	Fas (TNF receptor superfamily member 6)	0.061
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.060
Cd44	CD44 antigen	0.059
Tlr4	toll-like receptor 4	0.059
Notch2	Notch gene homolog 2 (Drosophila)	0.053
Vegfa	vascular endothelial growth factor A	0.050
Src	Rous sarcoma oncogene	0.049
Pparg	peroxisome proliferator activated receptor gamma	0.048	Mouse
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.048
Pycard	PYD and CARD domain containing	0.047
Apoe	apolipoprotein E	0.047	Human
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.042
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.042
Casp1	caspase 1	0.042
Rxra	retinoid X receptor alpha	0.042
Tlr2	toll-like receptor 2	0.042
Tgfb1	transforming growth factor, beta 1	0.041
Traf6	TNF receptor-associated factor 6	0.040
Ptgs2	prostaglandin-endoperoxide synthase 2	0.037
Plau	plasminogen activator, urokinase	0.035
Il1r1	interleukin 1 receptor, type I	0.035
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.033
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.033
Wt1	Wilms tumor 1 homolog	0.031
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.031
Hif1a	hypoxia inducible factor 1, alpha subunit	0.030
Agtr1a	angiotensin II receptor, type 1a	0.029	Mouse
Pcdh12	protocadherin 12	0.028
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.028
Smad4	MAD homolog 4 (Drosophila)	0.026
Lep	leptin	0.025
Nos1	nitric oxide synthase 1, neuronal	0.024
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.024
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.024
Nos2	nitric oxide synthase 2, inducible	0.023
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.023
Lox	lysyl oxidase	0.023
Csf1	colony stimulating factor 1 (macrophage)	0.022
Bdkrb2	bradykinin receptor, beta 2	0.022	Mouse
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.021
Agtrap	angiotensin II, type I receptor-associated protein	0.021
Ptrf	polymerase I and transcript release factor	0.020
Casp8	caspase 8	0.020
Acvrl1	activin A receptor, type II-like 1	0.020
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.020
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.019
Ren1	renin 1 structural	0.018
Hsd17b10	hydroxysteroid (17-beta) dehydrogenase 10	0.018
Ifng	interferon gamma	0.018
Ldlr	low density lipoprotein receptor	0.017
Bcar1	breast cancer anti-estrogen resistance 1	0.016
Cd40	CD40 antigen	0.016
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.016
Egfr	epidermal growth factor receptor	0.016
Insr	insulin receptor	0.015
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.015
Npy1r	neuropeptide Y receptor Y1	0.015
Apoa1	apolipoprotein A-I	0.015
Myd88	myeloid differentiation primary response gene 88	0.015
Col1a1	collagen, type I, alpha 1	0.015
Lrp1	low density lipoprotein receptor-related protein 1	0.015
Mstn	myostatin	0.015
Dll4	delta-like 4 (Drosophila)	0.014
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.014
Dmd	dystrophin, muscular dystrophy	0.014
Cav1	caveolin 1, caveolae protein	0.014
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.014
Clcn5	chloride channel 5	0.014
Fbn1	fibrillin 1	0.013
Plin1	perilipin 1	0.013
Grhpr	glyoxylate reductase/hydroxypyruvate reductase	0.013
Gna11	guanine nucleotide binding protein, alpha 11	0.013
Il1a	interleukin 1 alpha	0.013
En1	engrailed 1	0.012
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.012
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.012
Smad2	MAD homolog 2 (Drosophila)	0.012
Lif	leukemia inhibitory factor	0.012
Megf8	multiple EGF-like-domains 8	0.012
Ces1d	carboxylesterase 1D	0.012
Adcy4	adenylate cyclase 4	0.012
Rag1	recombination activating gene 1	0.012
Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	0.012
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.012
Esr1	estrogen receptor 1 (alpha)	0.011	Human
Il22	interleukin 22	0.011
Gm3776	predicted gene 3776	0.011
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.011
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.011
Apc	adenomatosis polyposis coli	0.011
Psen1	presenilin 1	0.011
Ly6d	lymphocyte antigen 6 complex, locus D	0.011
Vhl	von Hippel-Lindau tumor suppressor	0.011
Ednrb	endothelin receptor type B	0.011
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.011
Il4ra	interleukin 4 receptor, alpha	0.011
Nr3c2	nuclear receptor subfamily 3, group C, member 2	0.011
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.011
Itgb1bp2	integrin beta 1 binding protein 2	0.011
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.010
Mmp9	matrix metallopeptidase 9	0.010
Ooep	oocyte expressed protein homolog (dog)	0.010
Ret	ret proto-oncogene	0.010
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.010
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.010
Gstm1	glutathione S-transferase, mu 1	0.010