IMP

Process View

Mus musculus

3 genes annotated in mouse

Multi-species View

tricuspid valve development

GO:0003175

The progression of the tricuspid valve over time, from its formation to the mature structure.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "tricuspid valve development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "tricuspid valve development" (in gray)

Name	Description	Probability	Func Analog Organism
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	1.000
Pitx2	paired-like homeodomain transcription factor 2	0.999
Gata4	GATA binding protein 4	0.998
Hand2	heart and neural crest derivatives expressed transcript 2	0.998
Jag1	jagged 1	0.992
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.987
Foxc2	forkhead box C2	0.982
Tbx3	T-box 3	0.973	Mouse
Foxc1	forkhead box C1	0.933
Hoxa1	homeobox A1	0.928
Pax3	paired box gene 3	0.913
Shh	sonic hedgehog	0.911
Pax2	paired box gene 2	0.884
Scn5a	sodium channel, voltage-gated, type V, alpha	0.881
Fgf8	fibroblast growth factor 8	0.872
Hand1	heart and neural crest derivatives expressed transcript 1	0.853
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.840
Pitx1	paired-like homeodomain transcription factor 1	0.826
Fgfr2	fibroblast growth factor receptor 2	0.810
Efnb2	ephrin B2	0.800
Sox9	SRY-box containing gene 9	0.794
Tbx1	T-box 1	0.762	Mouse
Tgfb2	transforming growth factor, beta 2	0.724
Ntf3	neurotrophin 3	0.723
Prrx1	paired related homeobox 1	0.627
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.626
Chrd	chordin	0.593
Smad6	MAD homolog 6 (Drosophila)	0.554
Msx1	homeobox, msh-like 1	0.553
Tcfap2a	transcription factor AP-2, alpha	0.547
Foxg1	forkhead box G1	0.522
Bmp4	bone morphogenetic protein 4	0.491
Tbx5	T-box 5	0.444	Mouse
Gsc	goosecoid homeobox	0.388
Zfpm2	zinc finger protein, multitype 2	0.361	Mouse
Rxra	retinoid X receptor alpha	0.336
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.333
Tbx4	T-box 4	0.321	Mouse
Gata6	GATA binding protein 6	0.317
Gli3	GLI-Kruppel family member GLI3	0.294
Dlx5	distal-less homeobox 5	0.292
Isl1	ISL1 transcription factor, LIM/homeodomain	0.283
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.281
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.279	Mouse
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.249
Eya1	eyes absent 1 homolog (Drosophila)	0.239
Sall4	sal-like 4 (Drosophila)	0.228
Otx2	orthodenticle homolog 2 (Drosophila)	0.187
Lef1	lymphoid enhancer binding factor 1	0.185
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.180
Gja5	gap junction protein, alpha 5	0.176
Gata5	GATA binding protein 5	0.163
Alx1	ALX homeobox 1	0.148
Vangl2	vang-like 2 (van gogh, Drosophila)	0.148
Zeb1	zinc finger E-box binding homeobox 1	0.141
Runx2	runt related transcription factor 2	0.130
Ighmbp2	immunoglobulin mu binding protein 2	0.128
Mta1	metastasis associated 1	0.128
Gja1	gap junction protein, alpha 1	0.126
Col13a1	collagen, type XIII, alpha 1	0.125
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.123
Zic3	zinc finger protein of the cerebellum 3	0.120
Efna1	ephrin A1	0.120
Tbx20	T-box 20	0.098
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.094
Lrp6	low density lipoprotein receptor-related protein 6	0.093
Fgfr3	fibroblast growth factor receptor 3	0.088
Chd7	chromodomain helicase DNA binding protein 7	0.081
Bmp5	bone morphogenetic protein 5	0.078
Pax9	paired box gene 9	0.078
Klf3	Kruppel-like factor 3 (basic)	0.071
Bnc1	basonuclin 1	0.069
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.066
Gli2	GLI-Kruppel family member GLI2	0.066
Hoxa3	homeobox A3	0.066
Sox2	SRY-box containing gene 2	0.065
Bdnf	brain derived neurotrophic factor	0.056
Sox11	SRY-box containing gene 11	0.054
Msx2	homeobox, msh-like 2	0.053
Mesp1	mesoderm posterior 1	0.052
Dlx2	distal-less homeobox 2	0.051
Pou5f1	POU domain, class 5, transcription factor 1	0.050
Smo	smoothened homolog (Drosophila)	0.050
Nkx3-2	NK3 homeobox 2	0.049
Mn1	meningioma 1	0.049
Irx3	Iroquois related homeobox 3 (Drosophila)	0.047
Zic1	zinc finger protein of the cerebellum 1	0.047
Rarb	retinoic acid receptor, beta	0.046
Hoxd1	homeobox D1	0.045
Epha3	Eph receptor A3	0.045
Meox2	mesenchyme homeobox 2	0.043
Prrx2	paired related homeobox 2	0.043
Noto	notochord homolog (Xenopus laevis)	0.043
Gata1	GATA binding protein 1	0.042
Nanog	Nanog homeobox	0.041
Prdm6	PR domain containing 6	0.041
Wnt5a	wingless-related MMTV integration site 5A	0.040
Wnt3a	wingless-related MMTV integration site 3A	0.040
Tal1	T-cell acute lymphocytic leukemia 1	0.040
Cxadr	coxsackie virus and adenovirus receptor	0.038
Wt1	Wilms tumor 1 homolog	0.038
Hoxa2	homeobox A2	0.037
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.036
Mecom	MDS1 and EVI1 complex locus	0.036
Ryr2	ryanodine receptor 2, cardiac	0.035
Lrp5	low density lipoprotein receptor-related protein 5	0.035
Bmp7	bone morphogenetic protein 7	0.035
Foxf2	forkhead box F2	0.033
Myf5	myogenic factor 5	0.033
Foxi3	forkhead box I3	0.033
Lmx1a	LIM homeobox transcription factor 1 alpha	0.032
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.032
Shox2	short stature homeobox 2	0.031
Rnf2	ring finger protein 2	0.029
Twist2	twist homolog 2 (Drosophila)	0.029
Sall1	sal-like 1 (Drosophila)	0.029
Hrc	histidine rich calcium binding protein	0.029
Hoxa4	homeobox A4	0.027
Atoh8	atonal homolog 8 (Drosophila)	0.027
Gata2	GATA binding protein 2	0.026
Irx4	Iroquois related homeobox 4 (Drosophila)	0.026
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.026
Irx5	Iroquois related homeobox 5 (Drosophila)	0.025
Prdm1	PR domain containing 1, with ZNF domain	0.025
Heyl	hairy/enhancer-of-split related with YRPW motif-like	0.025	Mouse
Meox1	mesenchyme homeobox 1	0.024
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.023
Gata3	GATA binding protein 3	0.023
T	brachyury	0.023	Mouse
Snai1	snail homolog 1 (Drosophila)	0.023
Tbx2	T-box 2	0.023	Mouse
Ntf5	neurotrophin 5	0.022
Obsl1	obscurin-like 1	0.022
Hoxb2	homeobox B2	0.022
Zfp503	zinc finger protein 503	0.021
Cxcr7	chemokine (C-X-C motif) receptor 7	0.021
Hoxa10	homeobox A10	0.020
Wnt2	wingless-related MMTV integration site 2	0.020
Hes5	hairy and enhancer of split 5 (Drosophila)	0.020
Dnahc11	dynein, axonemal, heavy chain 11	0.020
Idua	iduronidase, alpha-L-	0.020
Nkd1	naked cuticle 1 homolog (Drosophila)	0.019
Gbx2	gastrulation brain homeobox 2	0.019
Bmp2	bone morphogenetic protein 2	0.019
Olig3	oligodendrocyte transcription factor 3	0.019
Cxcr4	chemokine (C-X-C motif) receptor 4	0.019
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.019
Hoxb4	homeobox B4	0.019
Ednra	endothelin receptor type A	0.018
Bves	blood vessel epicardial substance	0.018
Fbn2	fibrillin 2	0.018
Hoxb5	homeobox B5	0.018
Hoxd3	homeobox D3	0.018
Sos1	son of sevenless homolog 1 (Drosophila)	0.018
Vegfa	vascular endothelial growth factor A	0.018
Hoxb3	homeobox B3	0.018
Pax7	paired box gene 7	0.018
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.018
Ebf3	early B-cell factor 3	0.018
Sox7	SRY-box containing gene 7	0.018
Acvr1	activin A receptor, type 1	0.017
Nckap5l	NCK-associated protein 5-like	0.017
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.017
Ripply3	ripply3 homolog (zebrafish)	0.017
Fign	fidgetin	0.017
Capn6	calpain 6	0.017
Klf14	Kruppel-like factor 14	0.016
Hmga2	high mobility group AT-hook 2	0.016
Col2a1	collagen, type II, alpha 1	0.016
Hoxb6	homeobox B6	0.016
Dll4	delta-like 4 (Drosophila)	0.016
Tcf21	transcription factor 21	0.016
Sox17	SRY-box containing gene 17	0.015
Nrg1	neuregulin 1	0.015
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.015
Hhip	Hedgehog-interacting protein	0.015
Scube2	signal peptide, CUB domain, EGF-like 2	0.015
Xirp1	xin actin-binding repeat containing 1	0.015
Fgf18	fibroblast growth factor 18	0.014
Nkd2	naked cuticle 2 homolog (Drosophila)	0.014
Zbtb33	zinc finger and BTB domain containing 33	0.014
Dock1	dedicator of cytokinesis 1	0.014
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.014
Pou4f2	POU domain, class 4, transcription factor 2	0.014
Asb12	ankyrin repeat and SOCS box-containing 12	0.014
Foxa1	forkhead box A1	0.014
Hoxd8	homeobox D8	0.014
Cd274	CD274 antigen	0.013
Pcdh18	protocadherin 18	0.013
Myl7	myosin, light polypeptide 7, regulatory	0.013
Hoxc8	homeobox C8	0.013
Foxp2	forkhead box P2	0.013
Hoxa13	homeobox A13	0.013
Zbtb46	zinc finger and BTB domain containing 46	0.013
Zfhx4	zinc finger homeodomain 4	0.013
Otx1	orthodenticle homolog 1 (Drosophila)	0.013
Hapln1	hyaluronan and proteoglycan link protein 1	0.013
Cdx2	caudal type homeobox 2	0.013
Fgfr1	fibroblast growth factor receptor 1	0.013
Ebf2	early B-cell factor 2	0.013
Twist1	twist homolog 1 (Drosophila)	0.013
Asb10	ankyrin repeat and SOCS box-containing 10	0.012
Atp1b4	ATPase, (Na+)/K+ transporting, beta 4 polypeptide	0.012
Vstm2b	V-set and transmembrane domain containing 2B	0.012
Popdc3	popeye domain containing 3	0.012
Nfia	nuclear factor I/A	0.012
Tlx3	T-cell leukemia, homeobox 3	0.012
Cyp26c1	cytochrome P450, family 26, subfamily c, polypeptide 1	0.012
Notch3	Notch gene homolog 3 (Drosophila)	0.012
Alx4	aristaless-like homeobox 4	0.012
Mnx1	motor neuron and pancreas homeobox 1	0.012
En1	engrailed 1	0.012
Myocd	myocardin	0.012
She	src homology 2 domain-containing transforming protein E	0.012
Foxf1a	forkhead box F1a	0.012
Map4k2	mitogen-activated protein kinase kinase kinase kinase 2	0.012
Myl3	myosin, light polypeptide 3	0.012
Npr3	natriuretic peptide receptor 3	0.012
Gdnf	glial cell line derived neurotrophic factor	0.012
Axin2	axin2	0.012
Unc5c	unc-5 homolog C (C. elegans)	0.011
Tcf7	transcription factor 7, T-cell specific	0.011
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.011
Osr1	odd-skipped related 1 (Drosophila)	0.011
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.011
Dmrt3	doublesex and mab-3 related transcription factor 3	0.011
Hmx3	H6 homeobox 3	0.011
Thsd1	thrombospondin, type I, domain 1	0.011
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.011
Rybp	RING1 and YY1 binding protein	0.011
Fam89a	family with sequence similarity 89, member A	0.011
Nkg7	natural killer cell group 7 sequence	0.011
Hoxd9	homeobox D9	0.011
Arsb	arylsulfatase B	0.011
Nodal	nodal	0.011
Myoz2	myozenin 2	0.011
Adamts7	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7	0.011
Sp8	trans-acting transcription factor 8	0.011
Corin	corin	0.011
Kremen2	kringle containing transmembrane protein 2	0.010
Edar	ectodysplasin-A receptor	0.010
Wdr19	WD repeat domain 19	0.010
Wdr5	WD repeat domain 5	0.010
Gpc3	glypican 3	0.010
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.010
Rdh10	retinol dehydrogenase 10 (all-trans)	0.010
Vgll2	vestigial like 2 homolog (Drosophila)	0.010
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.010
Wnt5b	wingless-related MMTV integration site 5B	0.010